Water activated ionic conduction in cross-linked polyelectrolytes

The electrical properties of polyelectrolytes depend on the water concentration of the environment. The behaviour of both conductance and capacitance caused by variations in relative humidity and temperature was investigated by impedance spectroscopy for humidity sensors based on an interpenetrated network of a polymer and a polyelectrolyte. The results were interpreted on the base of the Langmuir and Kelvin equations and two different sensing mechanisms were highlighted for low and high water content

"Solid state charge trapping": Examples of polymer systems showing memory effect

The paper reports on a characteristic property of electroactive materials bearing an electron-rich and an electron-poor moiety, known as charge trapping. As examples of materials that exhibit this phenomenon, films of poly(4,4"-dipentoxy-4\u27-(2,2\u27-dicyano)ethenyl-2,2\u27:5\u27,2"-terthiophene), poly(2,3-dihexylthieno[3,4-b]pyrazine) and a blend between a fulleropyrrolidine derivative and poly(3-hexylthiophene) were investigated by cyclic voltammetry, spectroelectrochemistry and electrochemical quartz crystal microbalance. In the cyclic voltammetry, the reduction processes show the reverse oxidation potential about 1 V higher than the expected value, indicating a strong stabilization of the corresponding anion species. The mechanism leading to the stabilisation of the anions is discussed and the results indicate that the investigated materials exhibit a remarkable and quite stable memory effect

Morphology of the submerged Ferdinandea Island, the ‘Neverland’ of the Sicily Channel (central Mediterranean Sea)

We present the bathy-morphological map at a scale of 1: 50,000 of the area around the submerged Ferdinandea Island, the ‘Neverland’ of the Sicily Channel (central Mediterranean Sea). We investigate an area of 100 km2, between 10 and 350 m, which is part of a triangular morphological high, 360 km2 wide, representing the SE-wards prolongation of the Adventure Bank. The study is based on the morphometric analysis based on high resolution multibeam, and sub-bottom CHIRP profiles collected in 2015. The area around the remains of Ferdinandea Island is morphologically shaped by the interplay between volcanic, tectonic, fluid seepage, and oceanographic processes. Since the study area is considered a hot spot of biodiversity affected by maritime traffic (especially in Ferdinandea Channel) and hosting communication pipelines, this map provides insights both for habitat mapping purposes and preliminary marine geohazard assessment due to the occurrence of historically active submarine volcanoes, pockmarks, and mass transport deposits

An Integrated Multiscale Method for the Characterisation of Active Faults in Offshore Areas. The Case of Sant\u2019Eufemia Gulf (Offshore Calabria, Italy)

Diagnostic morphological features (e.g., rectilinear seafloor scarps) and lateral offsets of the Upper Quaternary deposits are used to infer active faults in offshore areas. Although they deform a significant seafloor region, the active faults are not necessarily capable of producing large earthquakes as they correspond to shallow structures formed in response to local stresses. We present a multiscale approach to reconstruct the structural pattern in offshore areas and distinguish between shallow, non-seismogenic, active faults, and deep blind faults, potentially associated with large seismic moment release. The approach is based on the interpretation of marine seismic reflection data and quantitative morphometric analysis of multibeam bathymetry, and tested on the Sant\u2019Eufemia Gulf (southeastern Tyrrhenian Sea). Data highlights the occurrence of three major tectonic events since the Late Miocene. The first extensional or transtensional phase occurred during the Late Miocene. Since the Early Pliocene, a right-lateral transpressional tectonic event caused the positive inversion of deep (>3 km) tectonic features, and the formation of NE-SW faults in the central sector of the gulf. Also, NNE-SSW to NE-SW trending anticlines (e.g., Maida Ridge) developed in the eastern part of the area. Since the Early Pleistocene (Calabrian), shallow (<1.5 km) NNE-SSW oriented structures formed in a left-lateral transtensional regime. The new results integrated with previous literature indicates that the Late Miocene to Recent transpressional/transtensional structures developed in an 3cE-W oriented main displacement zone that extends from the Sant\u2019Eufemia Gulf to the Squillace Basin (Ionian offshore), and likely represents the upper plate response to a tear fault of the lower plate. The quantitative morphometric analysis of the study area and the bathymetric analysis of the Angitola Canyon indicate that NNE-SSW to NE-SW trending anticlines were negatively reactivated during the last tectonic phase. We also suggest that the deep structure below the Maida Ridge may correspond to the seismogenic source of the large magnitude earthquake that struck the western Calabrian region in 1905. The multiscale approach contributes to understanding the tectonic imprint of active faults from different hierarchical orders and the geometry of seismogenic faults developed in a lithospheric strike-slip zone orthogonal to the Calabrian Arc

Mid-to-late Holocene upper slope contourite deposits off Capo Vaticano (Mediterranean Sea): High-resolution record of contourite cyclicity, bottom current variability and sandy facies

none13noThe upper continental slope offshore Capo Vaticano (southern Tyrrhenian Sea) is characterized by a contourite depositional system with well-developed elongated sediment drifts. This system is related to a northward paleo-bottom current, similar to the present-day modified-Levantine Intermediate Water (modified-LIW) flowing from the Messina Strait. In this work, we show results from an integrated analysis of descriptive oceanography, high-resolution seismic profiles and core data (i.e., grain size, foraminiferal assemblages, tephrostratigraphy and AMS radiocarbon dating) collected from the crest and moat sectors of drift deposits. The studied succession formed since the mid Holocene, under the action of the modified-LIW and the stratigraphic architecture indicates an upslope migration of the moat and rather stable position of the crest sector. Grain-size features recorded from two sediment cores indicate the occurrence of a succession of complete bi-gradational sand-rich contourite sequences. Sandy facies were observed both as lag deposits formed in active moat channel and as coarser intervals of bi-gradational sequences forming drift deposits close to its crest. Their occurrence would highlight that upper slope environments impacted by intermediate water masses and proximal to sandy sources may represent favorable settings for accumulation of sandy sediment. The moat sector is characterized by a more complex stratigraphic record, where either moat sedimentation or lateral deposition of finer sediment occur, suggesting that further investigation is required to better understand this complex element of contourite systems. Based on available age information, some of the bi-gradational sequences probably formed during the Dark Age Cold Period, providing example of a small-scale cyclicity of contourite deposition, likely related to short-term (possibly multicentennial scale) fluctuations of the paleo modified-LIW. According to age constraints and analysis of foraminiferal assemblages, these fluctuations were likely governed by climate variations, with a weaker activity during warmer periods and faster currents during colder events.openMartorelli E., Bosman A., Casalbore D., Chiocci F., Conte A.M., Di Bella L., Ercilla G., Falcini F., Falco P., Frezza V., Gaglianone G., Giaccio B., Mancini M.Martorelli, E.; Bosman, A.; Casalbore, D.; Chiocci, F.; Conte, A. M.; Di Bella, L.; Ercilla, G.; Falcini, F.; Falco, P.; Frezza, V.; Gaglianone, G.; Giaccio, B.; Mancini, M

Human Olfactory Bulb Neural Stem Cells (Hu-OBNSCs) Can Be Loaded with Paclitaxel and Used to Inhibit Glioblastoma Cell Growth

Exploitation of the potential ability of human olfactory bulb (hOB) cells to carry, release, and deliver an effective, targeted anticancer therapy within the central nervous system (CNS) milieu remains elusive. Previous studies have demonstrated the marked ability of several types of stem cells (such as mesenchymal stem cells (MSCs) to carry and release different anti-cancer agents such as paclitaxel (PTX). Herein we investigate the ability of human olfactory bulb neural stem cells (Hu-OBNSCs) to carry and release paclitaxel, producing effective cytotoxic effects against cancer cells. We isolated Hu-OBNSCs from the hOB, uploaded them with PTX, and studied their potential cytotoxic effects against cancer cells in vitro. Interestingly, the Hu-OBNSCs displayed a five-fold increase in their resistance to the cytotoxicity of PTX, and the PTX-uploaded Hu-OBNSCs were able to inhibit proliferation and invasion, and to trigger marked cytotoxic effects on glioblastoma multiforme (GBM) cancer cells, and Human Caucasian fetal pancreatic adenocarcinoma 1 (CFPAC-1) in vitro. Despite their ability to resist the cytotoxic activity of PTX, the mechanism by which Hu-OBNSCs acquire resistance to PTX is not yet explained. Collectively our data indicate the ability of the Hu-OBNSCs to resist PTX, and to trigger effective cytotoxic effects against GBM cancer cells and CFPAC-1. This indicates their potential to be used as a carrier/vehicle for targeted anti-cancer therapy within the CNS

Geohazard features of the Tyrrhenian Calabria

This paper accompanies the Maps of Geohazard features of the Cilento and the Calabro-Tyrrhenian continental margin in the southern Tyrrhenian Sea (Italy). The main geohazard-related features were derived from extensive seafloor mapping through the collection of high-resolution multibeam data acquired during several oceanographic cruises. They encompass many fluids seepage features, fault scarps, landslides scars, gullies, channels, and canyons. Hazards related to coastal landslides and shelf-indenting canyons are very high in these sectors (especially in southern Calabria) due to active seismicity coupled with rapid uplift, high sedimentation rates and narrow or totally absent continental shelf, thus promoting a direct connection between steep slopes and coastal areas. In this setting, mass-wasting features can directly impact coastal or submarine infrastructures or indirectly create local tsunami waves, as observed in historical times. Moreover, this physiographic setting of the margin facilitates the transfer of marine litter toward deep-sea areas

The Guadiaro-Baños contourite drifts (SW Mediterranean). A geotechnical approach to stability analysis

Two Quaternary plastered contourite drifts, with terraced and low-mounded morphologies, make up the continental slope and base-of-slope in the northwestern Alboran Sea, respectively, between the Guadiaro and Baños turbidite systems, close to the Strait of Gibraltar. Considering their significant lateral extent, the link between the contourite drift deposits and landslides may be particularly important for hazard assessment. The physical properties, composition and geometry of contourite drifts have been proposed as key factors in slope stability, although this relationship still needs to be better constrained. In this work, new in-situ geotechnical data (cone penetration tests; CPTu) has been combined with morphostratigraphic, sedimentological, and (laboratory) geotechnical properties to determine the stability of the Guadiaro-Baños drifts. For the depositional domains of both drifts, the resulting sedimentary and geotechnical model describes low-plasticity granular and silty sands on the erosive terraced domain that evolve seawards to silty and silty-clay deposits with a higher plasticity and uniform geomechanical properties. For the shallower coarse-grained contourite sediments, the cohesion (c') and internal friction angle (ϕ') values are 0–9 kPa and 46–30°, respectively, whereas for the distal fine contourites the undrained shear strength gradient (∇Su) is 2 kPa/m. These properties allow us to establish high factors of safety for all the scenarios considered, including seismic loading. Slope failure may be triggered in the unlikely event that there is seismic acceleration of PGA > 0.19, although no potential glide planes have been observed within the first 20 m below the seafloor. This suggests that the contourite drifts studied tend to resist failure better than others with similar sedimentary characteristics. The interplay of several processes is proposed to explain the enhanced undrained shear strength: 1) the geometry of the drifts, defined by an upper contouritic terrace and lower low-mounded shapes; 2) recurrent low-intensity earthquakes with insufficient energy to trigger landslides, favouring increased strength due to dynamic compaction; and 3) cyclic loading induced by solitons/internal waves acting on the sediment.En prens

Geohazard features of the north-western Sicily and Pantelleria

We present maps of geohazard features identified across north-western Sicily and Pantelleria in the framework of the Magic project (MArine Geohazard along Italian Coasts), which involved Italian marine geological researchers in 2007-2013. These seafloor features were recognized using high-resolution bathymetry data and rely on the morphological expression of the seafloor and shallow sub-surface processes. The north-western Sicily is a complex continental margin, affected by morphodynamic, depositional, and tectonic processes. The Egadi offshore is controlled by fault escarpments and alternating retreating and progradational processes. Ustica and Pantelleria submerged edifices show the effect of volcanic activity. The Ustica seafloor is interested in volcanic, tectonic, and gravitational instability processes, while the Pantelleria offshore underwent erosive-depositional processes and the effect of bottom currents. Two levels of interpretation are represented: the physiographic domain at a scale of 1:250.000 and the morphological units and morpho-bathymetric elements at a 1:100.000 scale

Integration of Remote Sensing and Offshore Geophysical Data for Monitoring the Short-Term Morphological Evolution of an Active Volcanic Flank: A Case Study from Stromboli Island

The Sciara del Fuoco (SdF) collapse scar at Stromboli is an active volcanic area affected by rapid morphological changes due to explosive/effusive eruptions and mass-wasting processes. The aim of this paper is to demonstrate the importance of an integrated analysis of multi-temporal remote sensing (photogrammetry, COSMO-SkyMed Synthetic Aperture Radar amplitude image) and marine geophysical data (multibeam and side scan sonar data) to characterize the main morphological, textural, and volumetric changes that occurred along the SdF slope in the 2020–2021 period. The analysis showed the marked erosive potential of the 19 May 2021 pyroclastic density current generated by a crater rim collapse, which mobilized a minimum volume of 44,000 m3 in the upper Sciara del Fuoco slope and eroded 350,000–400,000 m3 of material just considering the shallow-water setting. The analysis allowed us also to constrain the main factors controlling the emplacement of different lava flows and overflows during the monitored period. Despite the morphological continuity between the subaerial and submarine slope, textural variations in the SdF primarily depend on different processes and characteristics of the subaerial slope, the coastal area, the nearshore, and “deeper” marine areas