Magnetic control of superconducting vortices. Control magnético de vórtices superconductores

Tesis inédita de la Universidad Complutense de Madrid, Facultad de Ciencias Físicas, Departamento de Física de Materiales, leída el 30/09/2013Depto. de Física de MaterialesFac. de Ciencias FísicasTRUEunpu

Active core rewarming avoids bioelectrical impedance changes in postanesthetic patients

<p>Abstract</p> <p>Background</p> <p>Postoperative hypothermia is a common cause of complications in patients who underwent laparoscopic cholecystectomy. Hypothermia is known to elicit electrophysiological, biochemical, and cellular alterations thus leading to changes in the active and passive membrane properties. These changes might influence the bioelectrical impedance (BI). Our aim was to determine whether the BI depends on the core temperature.</p> <p>Methods</p> <p>We studied 60 patients (52 female and 8 male) age 40 to 80 years with an ASA I-II classification that had undergone laparoscopic cholecystectomy under balanced inhalation anesthesia. The experimental group (<it>n </it>= 30) received active core rewarming during the transanesthetic and postanesthesic periods. The control group (<it>n </it>= 30) received passive external rewarming. The BI was recorded by using a 4-contact electrode system to collect dual sets of measurements in the deltoid muscle. The body temperature, hemodynamic variables, respiratory rate, blood-gas levels, biochemical parameters, and shivering were also measured. The Mann-Whitney unpaired <it>t</it>-test was used to determine the differences in shivering between each group at each measurement period. Measurements of body temperature, hemodynamics variables, respiratory rate, and BI were analyzed using the two-way repeated-measures ANOVA.</p> <p>Results</p> <p>The gradual decrease in the body temperature was followed by the BI increase over time. The highest BI values (95 ± 11 Ω) appeared when the lowest values of the temperature (35.5 ± 0.5°C) were reached. The active core rewarming kept the body temperature within the physiological range (over 36.5°C). This effect was accompanied by low stable values (68 ± 3 Ω) of BI. A significant decrease over time in the hemodynamic values, respiratory rate, and shivering was seen in the active core-rewarming group when compared with the controls. The temporal course of shivering was different from those of body temperatue and BI. The control patients showed a significant increase in the serum-potassium levels, which were not seen in the active-core rewarming group.</p> <p>Conclusions</p> <p>The BI analysis changed as a function of the changes of core temperature and independently of the shivering. In addition, our results support the beneficial use of active core rewarming to prevent accidental hypothermia.</p

Analysis and performance of lumped-element kinetic inductance detectors for W-band

Lumped-element superconducting resonators are a promising technology for their use in millimeter-wave observations and quantum computing applications that require large arrays of extremely sensitive detectors. Among them, lumped-element kinetic inductance detectors (LEKIDs) have shown good performance in the submillimeter band in several earth-based telescopes. In this work, LEKIDs for their use as millimeter-wave receivers of astronomical applications are presented. LEKID arrays using a thin bilayer of superconducting titanium/aluminum (Ti/Al), deposited on the silicon substrate, have been designed and fabricated. The design of a dual-polarization LEKID with the goal of detection at the W -band for two orthogonal polarizations is described and a fabricated array has demonstrated absorption at ambient temperature. Also, an approximate design methodology of the coupling parameter for LEKIDs' readout, essential for dynamic range optimization of the detector under millimeter-wave radiation, is proposed. In addition, the resonance characteristics and coupling factor of the fabricated superconducting resonators using high-quality internal factor Qi under cryogenic temperatures have been analyzed. The design guidelines in this work are applicable to other LEKID arrays, and the presented superconducting Ti/Al thin-film LEKIDs can be used in future receiver arrays in the millimeter bands.This work was supported by Ministry of Science, Innovation and Universities under Grants ESP2017-83921-C2-2-R, ESP2017-86582-C4-1-R, ESP2017-86582-C4-3-R, ESP2017-92706-EXP, AYA2017-92153-EXP, “Severo Ochoa” Programme for Centres of Excellence in R&D (MINECO, Grant SEV-2016-0686). By Comunidad de Madrid under Grant P2018/NMT-4291. D.G. and A.G also acknowledge Grant DEFROST N62909-19-1-2053 from ONRGlobal. A.G. acknowledges IJCI-2017-33991

Remanence enhancement for stray field-based applications in arrays of crystalline nanomagnets

With the aim of achieving stable, substantial remanences adequate for exploitation in stray field-based applications, we report on the hysteresis behavior occurring in arrays of single-crystal Fe motifs, a-beam lithographed into prisms with triangular bases and different orientations of their magnetocrystalline axes with respect to the morphological symmetry axes. From both experimental and simulational analyses we recognize the fact that the magnetization reversal processes of our samples were mediated by motif-sized vortices. Their nucleation and annihilation fields and sites within the motifs, and their field-induced displacements, are discussed in terms of the magnetocrystalline and configurational anisotropies and inter-motif dipolar interactions. From our data, we conclude that reduced remanences as large as 0.85 (sufficient for the application requirements), protected by nucleation fields of several tens of Oe, can be produced in arrays where magnetocrystalline easy axes reinforce and partly compensate the easiest and hardest configurational ones, respectively. The angular dependence of the reduced remanence associated with interplay of these anisotropies corresponds to a symmetry reduction from the triaxial one linked to the triangular morphology down to an effective uniaxial one. We also identify, for the particular case of inter-nanoprism distances that are short in comparison with the dimensions of the motif base, a contribution to the remanence enhancement originating from the dipolar interactions

Radical scavenging and cellular antioxidant activity of the cocoa shell phenolic compounds after simulated digestion

The cocoa industry generates a considerable quantity of cocoa shell, a by-product with high levels of methylxanthines and phenolic compounds. Nevertheless, the digestion process can extensively modify these compounds’ bioaccessibility, bioavailability, and bioactivity as a consequence of their transformation. Hence, this work’s objective was to assess the influence of simulated gastrointestinal digestion on the concentration of phenolic compounds found in the cocoa shell flour (CSF) and the cocoa shell extract (CSE), as well as to investigate their radical scavenging capacity and antioxidant activity in both intestinal epithelial (IEC-6) and hepatic (HepG2) cells. The CSF and the CSE exhibited a high amount of methylxanthines (theobromine and caffeine) and phenolic compounds, mainly gallic acid and (+)-catechin, which persisted through the course of the simulated digestion. Gastrointestinal digestion increased the antioxidant capacity of the CSF and the CSE, which also displayed free radical scavenging capacity during the simulated digestion. Neither the CSF nor the CSE exhibited cytotoxicity in intestinal epithelial (IEC-6) or hepatic (HepG2) cells. Moreover, they effectively counteracted oxidative stress triggered by tert-butyl hydroperoxide (t-BHP) while preventing the decline of glutathione, thiol groups, superoxide dismutase, and catalase activities in both cell lines. Our study suggests that the cocoa shell may serve as a functional food ingredient for promoting health, owing to its rich concentration of antioxidant compounds that could support combating the cellular oxidative stress associated with chronic disease developmentThis research was funded by the COCARDIOLAC project from the Spanish Ministry of Science and Innovation (RTI 2018-097504-B-I00) and the Excellence Line for University Teaching Staff within the Multiannual Agreement between the Community of Madrid and the UAM (2019–2023). M. Rebollo-Hernanz received funding from the FPU program of the Ministry of Universities for his predoctoral fellowship (FPU15/04238) and a grant for the requalification of the Spanish university system (CA1/RSUE/2021-00656

Layer-dependence of macroscopic and atomic magnetic correlations in Co/Pd multilayers

The development of multilayered materials with engineered magnetic properties compels a deep knowledge of physical properties at the atomic scale. The magnetic anisotropy is a key property in these materials. This work accounts for the magnetic anisotropy energy and its correlation with atomic properties of Co/Pd multilayers with the number of Co/Pd repetitions. Magnetometry measurements confirm stronger perpendicular magnetic anisotropy energies as the number of repetitions increases up to 40. However, the intrinsic anisotropy, related to the Co-Pd orbital hybridization and spin-orbit coupling, saturates at 15 repetitions. This finding is supported by x-ray magnetic circular dichroism analysis that reveals a direct correlation of the atomic Co and Pd orbital magnetic moments and the effective anisotropy of the system. The proximity effect that accounts for the Pd induced magnetization, along with the increasing Co moment, provides a suitable mechanism for the observed anisotropy energy layer dependence

Bi-layer kinetic inductance detectors for W-band

An array of superconducting kinetic inductance detectors (KID) has been fabricated and it has demonstrated absorption at W-Band. The use of a bi-layer structure based on aluminum (AI) and titanium (Ti) shows a lower superconducting critical temperature (T c ), which allows the detection at W-band. A design methodology is presented taking into account the KID geometry in order to maximize the absorption and a dual-polarization KID has been designed using the proposed methodology. Two prototypes of KID on Silicon substrate have been fabricated showing a good agreement between measurement and simulation results. The measurements at room temperature from 65 to 110 GHz show the matching at the frequency band, while dark cryogenic characterization demonstrated the low frequency design.The authors acknowledge financial supports: Ministry of Science, Innovation and Universities Grants ESP2017-83921-C2-2-R, ESP2017-86582-C4-1-R, ESP2017-86582-C4-3-R, MAT2017-85617-R, ESP2017-92706-EXP, AYA2017-92153-EXP and from Comunidad de Madrid through Grant P2018/NMT-4291 TEC2-SPACE-CM. A.G. acknowledges IJCI-2017-33991; IMDEA Nanociencia acknowledges support from the “Severo Ochoa” Programme for Centres of Excellence in R&D (MINECO, Grant SEV-2016-0686). D.G. and A.G also acknowledge Grant DEFROST N62909-19-1-2053 from ONR-Global

Pathogen sensing device based on 2D MoS2/graphene heterostructure

In this work we propose a new methodology for selective and sensitive pathogen detection based on a 2D layered heterostructured biosensing platform. As a proof of concept, we have chosen SARS-CoV-2 virus because the availability of new methods to detect this virus is still a great deal of interest. The prepared platform is based on the covalent immobilization of molybdenum disulphide functionalized with a diazonium salt (f-MoS2) onto graphene screen-printed electrodes (GPH SPE) by electrografting of the diazonium salt. This chemistry-based method generates an improved heterostructured biosensing platform for aptamer immobilization and aptasensor development. Electrochemical impedance spectroscopy (EIS) is used to obtain the signal response of the device, proving the ability of the sensor platform to detect the virus. SARS-CoV-2 spike RBD recombinant protein (SARS-CoV-2 S1 protein) has been detected and quantified with a low detection limit of 2.10 fg/mL. The selectivity of the developed biosensor has been confirmed after detecting the S1 protein even in presence of other interfering proteins. Moreover, the ability of the device to detect SARS-CoV-2 S1 protein has been also tested in nasopharyngeal swab samplesThis work has been financially supported by the Spanish Ministry of Economy and Competitiveness (PID2020-116728RB-I00, PID2020- 116661RB-I00, CTQ2015-71955-REDT (ELECTROBIONET)) and Community of Madrid (TRANSNANOAVANSENS, S2018/NMT-4349, and PhotoArt P2018/NMT-4367). E. Enebral thank the financial support of “Nanotecnología para detección del SARS-CoV-2 y sus variantes. NANOCOV” project. IMDEA Nanociencia receives support from the “Severo Ochoa” Programme for Centres of Excellence in R&D (MINECO, Grant CEX2020-001039-S). We also thank the Spanish Ministry of Universities for supporting Laura Gutiérrez-Galvez with the Formación del Profesorado Universitario (FPU) grant (FPU19/06309