Short-Term Stocks, Long-Term Gains : Leveraging Implied Equity Duration in Portfolio Management

This thesis extends the literature on equity duration by analyzing stock market dynamics, particularly the short duration premium. Utilizing a robust dataset spanning from 1970 to 2022, our approach extends Weber’s (2018) work through various analytical frameworks, examining this phenomenon in depth. Significant findings include the identification of a short duration premium in the stock market, where stocks with shorter equity duration consistently outperform those with longer durations. This pattern, stable across various market conditions, challenges traditional asset pricing models, indicating a unique value in shorter-duration stocks. This thesis employed various factor models, from the CAPM to the Stambaugh-Yuan model. Each revealed insights but also significant unexplained returns in our SML-portfolio. This highlights the potential influence of market inefficiencies and behavioral aspects in asset pricing, suggesting new directions for future research in this area.nhhma

Unique thermal behavior of sphingomyelin species with nonhydroxy and 2-hydroxy very-long-chain (C28-C32) PUFAs

In rat germ cells and spermatozoa, sphingomyelin (SM) contains molecular species with nonhydroxy (n) and 2-hydroxy (h) very-long-chain polyunsaturated fatty acids (V), the most abundant being SMs with (n- and h-) 28:4n-6, 30:5n-6, and 32:5n-6 as acyl chains. The aim of this study was to gain information about their thermotropic behavior and interactions with other lipids. After isolation from rat testis, multilamellar and giant unilamellar vesicles from these SMs were examined using fluorescent probes. Only n-32:5 SM and h-32:5 SM displayed a gel-liquid transition temperature (Tt ≈ 21?22°C), the rest remaining in the liquid state in the 5°C?45°C range. The degree of order was larger in bilayers of any of the h-V SMs than in those of their chain-matched n-V SMs. Both, but n-V SM relatively more than h-V SM, decreased the Tt of dimyristoylphosphatidylcholine as their proportion increased in binary phosphatidylcholine:SM liposomes. In contrast to the established ability of 16:0 SM to form lateral cholesterol/SM-rich ordered domains in ternary dioleoylphosphatidylcholine:cholesterol:SM bilayers, neither n-V SM nor h-V SM showed a tendency to do so. Thus, these SMs are in the fluid state and are not involved in this type of domains in spermatozoa at physiological temperatures. However, this state could be altered at the very low temperatures at which these gametes are usually preserved.Fil: Peñalva, Daniel Alejandro. Consejo Nacional de Investigaciones Cientificas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Instituto de Investigaciones Bioquímicas Bahia Blanca (i); ArgentinaFil: Furland, Natalia Edith. Consejo Nacional de Investigaciones Cientificas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Instituto de Investigaciones Bioquímicas Bahia Blanca (i); ArgentinaFil: Lopez, Gustavo H.. Universidad Nacional del Sur. Departamento de Biología, Bioquímica y Farmacia; ArgentinaFil: Aveldaño, Marta Isabel. Consejo Nacional de Investigaciones Cientificas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Instituto de Investigaciones Bioquímicas Bahia Blanca (i); ArgentinaFil: Antollini, Silvia Susana. Consejo Nacional de Investigaciones Cientificas y Técnicas. Centro Científico Tecnológico Bahia Blanca. Instituto de Investigaciones Bioquímicas Bahia Blanca (i); Argentin

Biosynthesis of long-chain polyunsaturated fatty acids in marine fish: Characterization of an Elovl4-like elongase from cobia Rachycentron canadum and activation of the pathway during early life stages

Marine fish, unlike freshwater species, have been generally considered to have a limited ability to biosynthesize long-chain polyunsaturated fatty acids (LC-PUFA) from C18 precursors due to apparent limited enzymatic activities involved in the pathway. Although LC-PUFA play important physiological roles throughout the entire life cycle, requirements for early life stages are especially high and provision of preformed LC-PUFA in egg lipids appears critical to support the formation of developing tissues where these compounds accumulate. No studies, however, have been conducted to explore the capability of marine fish embryos (here referring to life stages from zygote to the oesophagus opening) for de novo synthesis of the LC-PUFA required for normal growth and development. The present study aimed to investigate the activation of the LC-PUFA biosynthetic pathway during embryogenesis of the marine teleost cobia (Rachycentron canadum). First, a fatty acyl elongase with sequence similarity to mammalian elongase of very long-chain fatty acids 4 (Elovl4) was isolated, and its biochemical function characterized showing that it catalyzed the production of very long-chain fatty acids (VLC-FA) including both saturated and polyunsaturated fatty acids with chain lenghts ≥ 24 carbons. Notably, cobia Elovl4 was able to elongate 22:5n-3 to 24:5n-3 and thus could play a key role in the biosynthesis of docosahexaenoic acid (22:6n-3), a critical fatty acid in neural tissues. Subsequently, the fatty acid dynamics of embryos at different developmental stages and the temporal expression patterns of target genes including elovl4, and the formerly characterized elovl5 elongase and ∆6 fatty acyl desaturase, were analyzed in order to elucidate the overall activation of the LC-PUFA biosynthetic pathway in cobia embryos. Our results indicated that expression of the LC-PUFA biosynthetic pathway in cobia embryos is initiated at 12-18 hours post-fertilization

Dephosphorylated NSSR1 Is Induced by Androgen in Mouse Epididymis and Phosphorylated NSSR1 Is Increased during Sperm Maturation

NSSR1 (Neural salient serine/arginine rich protein 1, alternatively SRp38) is a newly identified RNA splicing factor and predominantly expressed in neural tissues. Here, by Western blot analysis and immunofluorescent staining, we showed that the expression of dephosphorylated NSSR1 increased significantly during development of the caput epididymis. In adult mice, phosphorylated NSSR1 was mainly expressed in the apical side of epithelial cells, and dephosphorylated NSSR1 in caput epididymis was upregulated in a testosterone dependent manner. In addition, subcellular immunoreactive distribution of NSSR1 varied in different regions of the epididymis. With respect to the sperm, phosphorylated NSSR1 was detected in the mid-piece of the tail as well as the acrosome. Furthermore, NSSR1 was released from the sperm head during the capacitation and acrosome reaction. These findings for the first time provide the evidence for the potential roles of NSSR1 in sperm maturation and fertilization

Ponderosa pine pre-commercial thinning project

2013 Annual Meeting Presentatio

No effect of acute and chronic dietary nitrate supplementation on muscle oxygen consumption-recovery following exercise

AIM: The purpose of this study was to investigate the effect of acute and chronic ingestion of BR on mVO2-recovery of the vastus lateralis following exercise. METHOD: Nine healthy recreationally active men participated in a double-blind, placebo control, cross over design study, and ingested either 2x70 ml BR (2 x 450-500 mg nitrate) or PL (2 x 0.7 – 2.52 mg nitrate) per day for six days. MuscleVO2-recovery was measured using near infrared spectroscopy (NIRS) on vastus lateralis and rapid repeated occlusions on the right thigh immediately after cycling bouts on LI- and HI-intensity. Muscle-VO2 values were fit to a mono-exponential curve in order to calculate a time-constant and look for changes between BR and PL. RESULTS: No effect was found on mVO2-recovery following a seven minute cycling bout on LI after acute and chronic ingestion of BR. No effect was found on BP, and on pVO2 and HR from end-exercise, after acute and chronic supplementation. Discussion: No analysis on mVO2-recovery after cycling on HI were done in this study. This was due to an unforeseen prolonged elevation of mVO2-values, not seen on LI, making it difficult to fit a mono exponential curve and calculate a TC. Further research is necessary to investigate mVO2-recovery on higher intensity whole body exercise. Effect of BR on mVO2-recovery might not be expected due to no effect found on pVO2, BP and HR. This study is one of the first investigate mVO2-recovery following a whole body exercise, the effect of BR is uncertain at the time