5,844 research outputs found

    Robust multi-fidelity design of a micro re-entry unmanned space vehicle

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    This article addresses the preliminary robust design of a small-scale re-entry unmanned space vehicle by means of a hybrid optimization technique. The approach, developed in this article, closely couples an evolutionary multi-objective algorithm with a direct transcription method for optimal control problems. The evolutionary part handles the shape parameters of the vehicle and the uncertain objective functions, while the direct transcription method generates an optimal control profile for the re-entry trajectory. Uncertainties on the aerodynamic forces and characteristics of the thermal protection material are incorporated into the vehicle model, and a Monte-Carlo sampling procedure is used to compute relevant statistical characteristics of the maximum heat flux and internal temperature. Then, the hybrid algorithm searches for geometries that minimize the mean value of the maximum heat flux, the mean value of the maximum internal temperature, and the weighted sum of their variance: the evolutionary part handles the shape parameters of the vehicle and the uncertain functions, while the direct transcription method generates the optimal control profile for the re-entry trajectory of each individual of the population. During the optimization process, artificial neural networks are utilized to approximate the aerodynamic forces required by the optimal control solver. The artificial neural networks are trained and updated by means of a multi-fidelity approach: initially a low-fidelity analytical model, fitted on a waverider type of vehicle, is used to train the neural networks, and through the evolution a mix of analytical and computational fluid dynamic, high-fidelity computations are used to update it. The data obtained by the high-fidelity model progressively become the main source of updates for the neural networks till, near the end of the optimization process, the influence of the data obtained by the analytical model is practically nullified. On the basis of preliminary results, the adopted technique is able to predict achievable performance of the small spacecraft and the requirements in terms of thermal protection materials

    Clustering data by inhomogeneous chaotic map lattices

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    A new approach to clustering, based on the physical properties of inhomogeneous coupled chaotic maps, is presented. A chaotic map is assigned to each data-point and short range couplings are introduced. The stationary regime of the system corresponds to a macroscopic attractor independent of the initial conditions. The mutual information between couples of maps serves to partition the data set in clusters, without prior assumptions about the structure of the underlying distribution of the data. Experiments on simulated and real data sets show the effectiveness of the proposed algorithm.Comment: 8 pages, 6 figures. Revised version accepted for publication on Physical Review Letter

    Non-Fermi liquid behavior and scaling of low frequency suppression in optical conductivity spectra of CaRuO3_3

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    Optical conductivity spectra σ1(ω)\sigma_1(\omega) of paramagnetic CaRuO3_3 are investigated at various temperatures. At T=10 K, it shows a non-Fermi liquid behavior of σ1(ω)1/ω12\sigma_1(\omega)\sim 1/{\omega}^{\frac 12}, similar to the case of a ferromagnet SrRuO3_3. As the temperature (TT) is increased, on the other hand, σ1(ω)\sigma_1(\omega) in the low frequency region is progressively suppressed, deviating from the 1/{\omega}^{\frac 12%}-dependence. Interestingly, the suppression of σ1(ω)\sigma_1(\omega) is found to scale with ω/T\omega /T at all temperatures. The origin of the % \omega /T scaling behavior coupled with the non-Fermi liquid behavior is discussed.Comment: 4 pages, 3 figure

    A Terrestrial Planet in a ~1 AU Orbit Around One Member of a ~15 AU Binary

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    We detect a cold, terrestrial planet in a binary-star system using gravitational microlensing. The planet has low mass (2 Earth masses) and lies projected at a,pha_{\perp,ph} ~ 0.8 astronomical units (AU) from its host star, similar to the Earth-Sun distance. However, the planet temperature is much lower, T<60 Kelvin, because the host star is only 0.10--0.15 solar masses and therefore more than 400 times less luminous than the Sun. The host is itself orbiting a slightly more massive companion with projected separation a,ch=a_{\perp,ch}=10--15 AU. Straightforward modification of current microlensing search strategies could increase their sensitivity to planets in binary systems. With more detections, such binary-star/planetary systems could place constraints on models of planet formation and evolution. This detection is consistent with such systems being very common.Comment: Published in Science, Main and supplementary material combine

    Multiple signals mediate proliferation, differentiation, and survival from the granulocyte colony-stimulating factor receptor in myeloid 32D cells

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    Granulocyte colony-stimulating factor (G-CSF) regulates neutrophil production through activation of its cognate receptor, the G-CSF-R. Previous studies with deletion mutants have shown that the membrane-proximal cytoplasmic domain of the receptor is sufficient for mitogenic signaling, whereas the membrane-distal domain is required for differentiation signaling. However, the function of the four cytoplasmic tyrosines of the G-CSF-R in the control of proliferation, differentiation, and survival has remained unclear. Here we investigated the role of these tyrosines by expressing a tyrosine 'null' mutant and single tyrosine 'add back' mutants in maturation-competent myeloid 32D cells. Clones expressing the null mutant showed only minimal proliferation and differentiation, with survival also reduced at low G-CSF concentrations. Analysis of clones expressing the add-back mutants revealed that multiple tyrosines contribute to proliferation, differentiation, and survival signals from the G-CSF-R. Analysis of signaling pathways downstream of these tyrosines suggested a positive role for STAT3 activation in both differentiation and survival signaling, whereas SHP-2, Grb2 and Shc appear important for proliferation signaling. In addition, we show that a tyrosine- independent 'differentiation domain' in the membrane-distal region of the G- CSF-R appears necessary but not sufficient for mediating neutrophilic differentiation in these cells

    Representing complex data using localized principal components with application to astronomical data

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    Often the relation between the variables constituting a multivariate data space might be characterized by one or more of the terms: ``nonlinear'', ``branched'', ``disconnected'', ``bended'', ``curved'', ``heterogeneous'', or, more general, ``complex''. In these cases, simple principal component analysis (PCA) as a tool for dimension reduction can fail badly. Of the many alternative approaches proposed so far, local approximations of PCA are among the most promising. This paper will give a short review of localized versions of PCA, focusing on local principal curves and local partitioning algorithms. Furthermore we discuss projections other than the local principal components. When performing local dimension reduction for regression or classification problems it is important to focus not only on the manifold structure of the covariates, but also on the response variable(s). Local principal components only achieve the former, whereas localized regression approaches concentrate on the latter. Local projection directions derived from the partial least squares (PLS) algorithm offer an interesting trade-off between these two objectives. We apply these methods to several real data sets. In particular, we consider simulated astrophysical data from the future Galactic survey mission Gaia.Comment: 25 pages. In "Principal Manifolds for Data Visualization and Dimension Reduction", A. Gorban, B. Kegl, D. Wunsch, and A. Zinovyev (eds), Lecture Notes in Computational Science and Engineering, Springer, 2007, pp. 180--204, http://www.springer.com/dal/home/generic/search/results?SGWID=1-40109-22-173750210-
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