Root ABA and H+-ATPase are key players in the root and shoot growth-promoting action of humic acids

Although the ability of humic (HA) and fulvic acids (FA) to improve plant growth has been demonstrated, knowledge about the mechanisms responsible for the direct effects of HA and FA on the promotion of plant growth is scarce and fragmentary. Our study investigated the causal role of both root PM H+-ATPase activity and ABA in the SHA-promoting action on both root and shoot growth. The involvement of these processes in the regulation of shoot cytokinin concentration and activity was also studied. Our aim was to integrate such plant responses for providing new insights to the current model on the mode of action of HA for promoting root and shoot growth. Experiments employing specific inhibitors and using Cucumis sativus L. plants show that both the root PM H+-ATPase activity and root ABA play a crucial role in the root growth-promoting action of SHA. With regard to the HA-promoting effects on shoot growth, two pathways of events triggered by the interaction of SHA with plant roots are essential for the increase in root PM H+-ATPase activity-which also mediates an increase in cytokinin concentration and action in the shoot-and the ABA-mediated increase in hydraulic conductivity (Lp(r))

DLT 4-411. Scale : the development of the typical speech

1 archivo PDF (18 páginas). fhundequinquagintaLas características de una escala cuyo propósito consiste en determinar fidedignamente el nivel del desarrollo del lenguaje típico en niños de edad preescolar se describen en este artículo. La escala referida evalúa el desarrollo del proceso para adquirir la fonología, morfología, sintaxis y pragmática de niños hablantes del español cuyas edades se hallen delimitadas por 4 años y 4 años 11 meses. Abstract The characteristics and the process of developing a scale that aims at determining the level of typical language development in children of pre school age are described in this article. The scale assesses the above mentioned development of phonology, morphology, syntax and pragmatics of children whose ages are between four and four years eleven months. PALABRAS CLAVE: adquisición, evaluación, lenguaje, escala. KEY WORDS: acquisition, assessment, language, leve

First Latin American clinical practice guidelines for the treatment of systemic lupus erythematosus: Latin American Group for the Study of Lupus (GLADEL, Grupo Latino Americano de Estudio del Lupus)-Pan-American League of Associations of Rheumatology (PANLAR)

Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents a significant challenge for both diagnosis and treatment. Patients with SLE in Latin America face special problems that should be considered when therapeutic guidelines are developed. The objective of the study is to develop clinical practice guidelines for Latin American patients with lupus. Two independent teams (rheumatologists with experience in lupus management and methodologists) had an initial meeting in Panama City, Panama, in April 2016. They selected a list of questions for the clinical problems most commonly seen in Latin American patients with SLE. These were addressed with the best available evidence and summarised in a standardised format following the Grading of Recommendations Assessment, Development and Evaluation approach. All preliminary findings were discussed in a second face-to-face meeting in Washington, DC, in November 2016. As a result, nine organ/system sections are presented with the main findings; an 'overarching' treatment approach was added. Special emphasis was made on regional implementation issues. Best pharmacologic options were examined for musculoskeletal, mucocutaneous, kidney, cardiac, pulmonary, neuropsychiatric, haematological manifestations and the antiphospholipid syndrome. The roles of main therapeutic options (ie, glucocorticoids, antimalarials, immunosuppressant agents, therapeutic plasma exchange, belimumab, rituximab, abatacept, low-dose aspirin and anticoagulants) were summarised in each section. In all cases, benefits and harms, certainty of the evidence, values and preferences, feasibility, acceptability and equity issues were considered to produce a recommendation with special focus on ethnic and socioeconomic aspects. Guidelines for Latin American patients with lupus have been developed and could be used in similar settings.Fil: Pons Estel, Bernardo A.. Centro Regional de Enfermedades Autoinmunes y Reumáticas; ArgentinaFil: Bonfa, Eloisa. Universidade de Sao Paulo; BrasilFil: Soriano, Enrique R.. Instituto Universitario Hospital Italiano de Buenos Aires. Rectorado.; ArgentinaFil: Cardiel, Mario H.. Centro de Investigación Clínica de Morelia; MéxicoFil: Izcovich, Ariel. Hospital Alemán; ArgentinaFil: Popoff, Federico. Hospital Aleman; ArgentinaFil: Criniti, Juan M.. Hospital Alemán; ArgentinaFil: Vásquez, Gloria. Universidad de Antioquia; ColombiaFil: Massardo, Loreto. Universidad San Sebastián; ChileFil: Duarte, Margarita. Hospital de Clínicas; ParaguayFil: Barile Fabris, Leonor A.. Hospital Angeles del Pedregal; MéxicoFil: García, Mercedes A.. Universidad de Buenos Aires. Facultad de Medicina. Hospital de Clínicas General San Martín; ArgentinaFil: Amigo, Mary Carmen. Centro Médico Abc; MéxicoFil: Espada, Graciela. Gobierno de la Ciudad de Buenos Aires. Hospital General de Niños "Ricardo Gutiérrez"; ArgentinaFil: Catoggio, Luis J.. Hospital Italiano. Instituto Universitario. Escuela de Medicina; ArgentinaFil: Sato, Emilia Inoue. Universidade Federal de Sao Paulo; BrasilFil: Levy, Roger A.. Universidade do Estado de Rio do Janeiro; BrasilFil: Acevedo Vásquez, Eduardo M.. Universidad Nacional Mayor de San Marcos; PerúFil: Chacón Díaz, Rosa. Policlínica Méndez Gimón; VenezuelaFil: Galarza Maldonado, Claudio M.. Corporación Médica Monte Sinaí; EcuadorFil: Iglesias Gamarra, Antonio J.. Universidad Nacional de Colombia; ColombiaFil: Molina, José Fernando. Centro Integral de Reumatología; ColombiaFil: Neira, Oscar. Universidad de Chile; ChileFil: Silva, Clóvis A.. Universidade de Sao Paulo; BrasilFil: Vargas Peña, Andrea. Hospital Pasteur Montevideo; UruguayFil: Gómez Puerta, José A.. Hospital Clinic Barcelona; EspañaFil: Scolnik, Marina. Instituto Universitario Hospital Italiano de Buenos Aires. Rectorado.; ArgentinaFil: Pons Estel, Guillermo J.. Centro Regional de Enfermedades Autoinmunes y Reumáticas; Argentina. Hospital Provincial de Rosario; ArgentinaFil: Ugolini Lopes, Michelle R.. Universidade de Sao Paulo; BrasilFil: Savio, Verónica. Instituto Universitario Hospital Italiano de Buenos Aires. Rectorado.; ArgentinaFil: Drenkard, Cristina. University of Emory; Estados UnidosFil: Alvarellos, Alejandro J.. Hospital Privado Universitario de Córdoba; ArgentinaFil: Ugarte Gil, Manuel F.. Universidad Cientifica del Sur; Perú. Hospital Nacional Guillermo Almenara Irigoyen; PerúFil: Babini, Alejandra. Instituto Universitario Hospital Italiano de Buenos Aires. Rectorado.; ArgentinaFil: Cavalcanti, André. Universidade Federal de Pernambuco; BrasilFil: Cardoso Linhares, Fernanda Athayde. Hospital Pasteur Montevideo; UruguayFil: Haye Salinas, Maria Jezabel. Hospital Privado Universitario de Córdoba; ArgentinaFil: Fuentes Silva, Yurilis J.. Universidad de Oriente - Núcleo Bolívar; VenezuelaFil: Montandon De Oliveira E Silva, Ana Carolina. Universidade Federal de Goiás; BrasilFil: Eraso Garnica, Ruth M.. Universidad de Antioquia; ColombiaFil: Herrera Uribe, Sebastián. Hospital General de Medellin Luz Castro de Gutiérrez; ColombiaFil: Gómez Martín, DIana. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Robaina Sevrini, Ricardo. Universidad de la República; UruguayFil: Quintana, Rosana M.. Hospital Provincial de Rosario; Argentina. Centro Regional de Enfermedades Autoinmunes y Reumáticas; ArgentinaFil: Gordon, Sergio. Hospital Interzonal General de Agudos Dr Oscar Alende. Unidad de Reumatología y Enfermedades Autoinmunes Sistémicas; ArgentinaFil: Fragoso Loyo, Hilda. Instituto Nacional de la Nutrición Salvador Zubiran; MéxicoFil: Rosario, Violeta. Hospital Docente Padre Billini; República DominicanaFil: Saurit, Verónica. Hospital Privado Universitario de Córdoba; ArgentinaFil: Appenzeller, Simone. Universidade Estadual de Campinas; BrasilFil: Dos Reis Neto, Edgard Torres. Universidade Federal de Sao Paulo; BrasilFil: Cieza, Jorge. Hospital Nacional Edgardo Rebagliati Martins; PerúFil: González Naranjo, Luis A.. Universidad de Antioquia; ColombiaFil: González Bello, Yelitza C.. Ceibac; MéxicoFil: Collado, María Victoria. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Sarano, Judith. Universidad de Buenos Aires. Facultad de Medicina. Instituto de Investigaciones Médicas; ArgentinaFil: Retamozo, Maria Soledad. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto de Investigaciones en Ciencias de la Salud. Universidad Nacional de Córdoba. Instituto de Investigaciones en Ciencias de la Salud; ArgentinaFil: Sattler, María E.. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Gamboa Cárdenas, Rocio V.. Hospital Nacional Guillermo Almenara Irigoyen; PerúFil: Cairoli, Ernesto. Universidad de la República; UruguayFil: Conti, Silvana M.. Hospital Provincial de Rosario; ArgentinaFil: Amezcua Guerra, Luis M.. Instituto Nacional de Cardiologia Ignacio Chavez; MéxicoFil: Silveira, Luis H.. Instituto Nacional de Cardiologia Ignacio Chavez; MéxicoFil: Borba, Eduardo F.. Universidade de Sao Paulo; BrasilFil: Pera, Mariana A.. Hospital Interzonal General de Agudos General San Martín; ArgentinaFil: Alba Moreyra, Paula B.. Universidad Nacional de Córdoba. Facultad de Medicina; ArgentinaFil: Arturi, Valeria. Hospital Interzonal General de Agudos General San Martín; ArgentinaFil: Berbotto, Guillermo A.. Provincia de Buenos Aires. Ministerio de Salud. Hospital Interzonal de Agudos "Eva Perón"; ArgentinaFil: Gerling, Cristian. Hospital Interzonal General de Agudos Dr Oscar Alende. Unidad de Reumatología y Enfermedades Autoinmunes Sistémicas; ArgentinaFil: Gobbi, Carla Andrea. Universidad Nacional de Córdoba. Facultad de Medicina; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Gervasoni, Viviana L.. Hospital Provincial de Rosario; ArgentinaFil: Scherbarth, Hugo R.. Hospital Interzonal General de Agudos Dr Oscar Alende. Unidad de Reumatología y Enfermedades Autoinmunes Sistémicas; ArgentinaFil: Brenol, João C. Tavares. Hospital de Clinicas de Porto Alegre; BrasilFil: Cavalcanti, Fernando. Universidade Federal de Pernambuco; BrasilFil: Costallat, Lilian T. Lavras. Universidade Estadual de Campinas; BrasilFil: Da Silva, Nilzio A.. Universidade Federal de Goiás; BrasilFil: Monticielo, Odirlei A.. Hospital de Clinicas de Porto Alegre; BrasilFil: Seguro, Luciana Parente Costa. Universidade de Sao Paulo; BrasilFil: Xavier, Ricardo M.. Hospital de Clinicas de Porto Alegre; BrasilFil: Llanos, Carolina. Universidad Católica de Chile; ChileFil: Montúfar Guardado, Rubén A.. Instituto Salvadoreño de la Seguridad Social; El SalvadorFil: Garcia De La Torre, Ignacio. Hospital General de Occidente; MéxicoFil: Pineda, Carlos. Instituto Nacional de Rehabilitación; MéxicoFil: Portela Hernández, Margarita. Umae Hospital de Especialidades Centro Medico Nacional Siglo Xxi; MéxicoFil: Danza, Alvaro. Hospital Pasteur Montevideo; UruguayFil: Guibert Toledano, Marlene. Medical-surgical Research Center; CubaFil: Reyes, Gil Llerena. Medical-surgical Research Center; CubaFil: Acosta Colman, Maria Isabel. Hospital de Clínicas; ParaguayFil: Aquino, Alicia M.. Hospital de Clínicas; ParaguayFil: Mora Trujillo, Claudia S.. Hospital Nacional Edgardo Rebagliati Martins; PerúFil: Muñoz Louis, Roberto. Hospital Docente Padre Billini; República DominicanaFil: García Valladares, Ignacio. Centro de Estudios de Investigación Básica y Clínica; MéxicoFil: Orozco, María Celeste. Instituto de Rehabilitación Psicofísica; ArgentinaFil: Burgos, Paula I.. Pontificia Universidad Católica de Chile; ChileFil: Betancur, Graciela V.. Instituto de Rehabilitación Psicofísica; ArgentinaFil: Alarcón, Graciela S.. Universidad Peruana Cayetano Heredia; Perú. University of Alabama at Birmingahm; Estados Unido

Ultralight vector dark matter search using data from the KAGRA O3GK run

Among the various candidates for dark matter (DM), ultralight vector DM can be probed by laser interferometric gravitational wave detectors through the measurement of oscillating length changes in the arm cavities. In this context, KAGRA has a unique feature due to differing compositions of its mirrors, enhancing the signal of vector DM in the length change in the auxiliary channels. Here we present the result of a search for U(1)B−L gauge boson DM using the KAGRA data from auxiliary length channels during the first joint observation run together with GEO600. By applying our search pipeline, which takes into account the stochastic nature of ultralight DM, upper bounds on the coupling strength between the U(1)B−L gauge boson and ordinary matter are obtained for a range of DM masses. While our constraints are less stringent than those derived from previous experiments, this study demonstrates the applicability of our method to the lower-mass vector DM search, which is made difficult in this measurement by the short observation time compared to the auto-correlation time scale of DM

Tolerancia del tomate (Lycopersicon esculentum Mill.) a aplicaciones post trasplante del herbicida halosulfurón-metil.

Durante la temporada 1998/99 en el Centro Regional de Investigación La Platina del Instituto de Investigaciones Agropecuarias (INIA) (33º34¿ lat. Sur, 70º38¿ long. Oeste, 625 m.s.n.m.), en un suelo franco-arcilloso, se realizaron ensayos para determinar la tolerancia de tomate (Lycopersicon esculentum Mill.) de los cultivares industriales H-993, P-76, APT-127, APT-410 y cultivares de consumo fresco Cal Ace y XPH-12221 a aplicaciones de post trasplante de halosulfurón-metil (Sempra® 75 WG) en la dosis recomendada 75 g ha-1 y en sobredosis de 150 y 300 g ha-1. En todas las dosis halosulfurón-metil no produjo síntomas adversos importantes sobre el follaje. Los mayores niveles de decoloración foliar se observaron en la sobredosis 300 g ha-1 en el cv. P-76 siete días después de la aplicación (DDA). Esta fitotoxicidad fue temporal, restringida a 7-15 DDA, desapareciendo casi completamente 21 DDA. No hubo reducciones en alto y ancho de las plantas 30 DDA, a excepción del ancho del cv. P-76 a 300 g ha-1. 0El rendimiento individual y total de frutos en los cvs. Cal Ace, XPH-12221, H-993, APT-127 y APT-410 no fueron afectados por las aplicaciones de halosulfurón-metil. Ninguna dosis produjo efectos adversos en el diámetro ecuatorial y polar de los frutos. El híbrido industrial P-76 tuvo una baja significativa en rendimiento y número de frutos planta-1 a 150 y 300 g ha-1, pero no con la dosis de 75 g ha-1. Las plantas de tomate fueron tolerantes a aplicaciones tempranas de post trasplante en la dosis máxima recomendada de halosulfurón-metil

INVESTIGACIÓN - TOLERANCIA DEL TOMATE (Lycopersicon esculentum Mill.) A APLICACIONES POST TRASPLANTE DEL HERBICIDA HALOSULFURÓN-METIL (Tomato (Lycopersicon esculentum Mill.) tolerance to post transplant applications of the herbicide halosulfuron-methyl)

Durante la temporada 1998/99 en el Centro Regional de Investigación La Platina del Instituto de Investigaciones Agropecuarias (INIA) (33o34' lat. Sur, 70o38' long. Oeste, 625 m.s.n.m.), en un suelo franco-arcilloso, se realizaron ensayos para determinar la tolerancia de tomate (Lycopersicon esculentum Mill.) de los cultivares industriales H-993, P-76, APT-127, APT-410 y cultivares de consumo fresco Cal Ace y XPH-12221 a aplicaciones de post trasplante de halosulfurón-metil (Sempra 75 WG) en la dosis recomendada 75 g ha-1 y en sobredosis de 150 y 300 g ha-1. En todas las dosis halosulfurón-metil no produjo síntomas adversos importantes sobre el follaje. Los mayores niveles de decoloración foliar se observaron en la sobredosis 300 g ha-1 en el cv. P-76 siete días después de la aplicación (DDA). Esta fitotoxicidad fue temporal, restringida a 7-15 DDA, desapareciendo casi completamente 21 DDA. No hubo reducciones en alto y ancho de las plantas 30 DDA, a excepción del ancho del cv. P-76 a 300 g ha-1. 0El rendimiento individual y total de frutos en los cvs. Cal Ace, XPH-12221, H-993, APT-127 y APT-410 no fueron afectados por las aplicaciones de halosulfurón-metil. Ninguna dosis produjo efectos adversos en el diámetro ecuatorial y polar de los frutos. El híbrido industrial P-76 tuvo una baja significativa en rendimiento y número de frutos planta-1 a 150 y 300 g ha-1, pero no con la dosis de 75 g ha-1. Las plantas de tomate fueron tolerantes a aplicaciones tempranas de post trasplante en la dosis máxima recomendada de halosulfurón-metil. Tomato (Lycopersicon esculentum Mill.) tolerance to post transplant applications of the herbicide halosulfuron-methyl. During the 1998/99 season at La Platina Research Regional Center of the National Agricultural Research Institute (INIA) (33o34' S lat, 70o38' W long, altitude 625 m.o.s.l.), on a loamy-clay soil, field trials were conducted to determine crop tolerance of tomatoes (Lycopersicon esculentum Mill.) of the industrial cultivars H-993, P-76, APT-127, APT-410, and fresh consumption cultivars Cal Ace, and XPH-12221, to post transplant applications of halosulfuron-methyl (Sempra? 75 WG) at the recommended rate 75 g ha-1 and at an overdose of 150 and 300 g ha-1. At all of the doses halosulfuron-methyl did not produce any significant adverse effects on the foliage. The greatest levels of foliar discoloration were observed on cv. P-76 at 300 g ha-1 seven days after treatment (DDA). This phytotoxicity was temporary, restricted to 7-15 DDA, disappearing almost completely at 21 DDA. There was no reduction in plant height and width to 30 DDA, except the width of cv. P-76 treated at 300 g ha-1. Single plant and total tomato yield of the varieties Cal Ace, XPH-12221, H-993, APT-127 y APT-410 were not affected by any herbicide applications of halosulfuron-methyl. No dose produced adverse effects on the polar and equatorial fruit diameter. The industrial hybrid P-76 had a significant reduction in total fruit yield and number of fruit per plant at 150 and 300 g ha-1, but not at 75 g ha-1. Tomato plants were tolerant to early post transplant applications at the normal recommended rate of halosulfuron-methyl

Factors related to medication errors in the preparation and administration of intravenous medication in the hospital environment

Background Medication errors have long been associated with low-quality medical care services and significant additional medical costs. Objective The aim of this study was to culturally adapt and validate the questionnaire on knowledge, attitudes and behaviors in the administration of intravenous medication, as well as to explore these factors in a hospital setting. Methods The study was divided into two phases: 1) validation and cross-cultural adaptation, and 2) cross-sectional study. A total of 276 hospital-based nursing professionals participated in the study. Results A Cronbach’s alpha value of 0.849 was found, indicating good internal consistency. In the multivariate analysis, statistically significant differences were found between knowledge and attitudes, demonstrating that having greater suitable knowledge correlates with having a more positive attitude. It was also discovered that having a positive attitude as well as the necessary knowledge increases the possibility of engaging in adequate behaviors. Conclusions The knowledge, attitudes and behavior questionnaire has a satisfactory internal consistency in order to be applied to the Spanish context. Implications for nursing management: Knowledge acquisition and positive attitude are both factors which promote adequate behavior, which in turn seems to have an impact on medication errors prevention. Health institutions must encourage continuous education for their employees