18 research outputs found
Restriction fragment length polymorphisms among the flagellar genes of the Lior heat-labile serogroup reference strains and field strains of Campylobacter jejuni and C. coli
Several typing systems have been described for Campylobacter jejuni and C. coli, to assess the complex epidemiology of these important enteric pathogens. In the present study two typing methods, slide agglutination according to the Lior scheme, and the demonstration of restriction-fragment length polymorphisms (RFLP) of flagellar genes, have been used in parallel on a set of 194 strains. This set comprised 118 sero-reference strains of C. jejuni and C. coli of the Lior scheme, as well as 76 clinical isolates. All isolates were serotyped and subjected to PCR for amplification of flagellar genes, and the PCR product was restricted with Alu I. Flagellar genes could be amplified in 152 strains. Among 85 seroreference strains, 74 different RFLP patterns were observed, and among 67 clinical isolates, there were 36 patterns. There was only limited correlation between flagellar RFLP and the Lior serogroup, and the variability of patterns in serogroups HL2 and HL4 were as marked as the variability between serogroups. Flagellar gene RFLP patterns are shown to be stable, highly discriminatory epidemiologic marker
Alginate-regulating genes are identified in the clinical cystic fibrosis isolate of Pseudomonas aeruginosa PA2192
Diffusive and Ballistic Transport in Ultra-thin InSb Nanowire Devices Using a Few-layer-Graphene-AlOx Gate
Quantum devices based on InSb nanowires (NWs) are a prime candidate system
for realizing and exploring topologically-protected quantum states and for
electrically-controlled spin-based qubits. The influence of disorder on
achieving reliable topological regimes has been studied theoretically,
highlighting the importance of optimizing both growth and nanofabrication. In
this work we investigate both aspects. We developed InSb nanowires with
ultra-thin diameters, as well as a new gating approach, involving few-layer
graphene (FLG) and Atomic Layer Deposition (ALD)-grown AlOx. Low-temperature
electronic transport measurements of these devices reveal conductance plateaus
and Fabry-P\'erot interference, evidencing phase-coherent transport in the
regime of few quantum modes. The approaches developed in this work could help
mitigate the role of material and fabrication-induced disorder in
semiconductor-based quantum devices.Comment: 14 pages, 5 figure
Restriction fragment length polymorphisms among the flagellar genes of the Lior heat-labile serogroup reference strains and field strains of Campylobacter jejuni and C. coli.
Several typing systems have been described for Campylobacter jejuni and C. coli, to assess the complex epidemiology of these important enteric pathogens. In the present study two typing methods, slide agglutination according to the Lior scheme, and the demonstration of restriction-fragment length polymorphisms (RFLP) of flagellar genes, have been used in parallel on a set of 194 strains. This set comprised 118 sero-reference strains of C. jejuni and C. coli of the Lior scheme, as well as 76 clinical isolates. All isolates were serotyped and subjected to PCR for amplification of flagellar genes, and the PCR product was restricted with Alu I. Flagellar genes could be amplified in 152 strains. Among 85 seroreference strains, 74 different RFLP patterns were observed, and among 67 clinical isolates, there were 36 patterns. There was only limited correlation between flagellar RFLP and the Lior serogroup, and the variability of patterns in serogroups HL2 and HL4 were as marked as the variability between serogroups. Flagellar gene RFLP patterns are shown to be stable, highly discriminatory epidemiologic markers
Alginate-regulating genes are identified in the clinical cystic fibrosis isolate of Pseudomonas aeruginosa PA2192
Understanding and Promoting Molecular Interactions and Charge Transfer in Dye-Mediated Hybrid Photovoltaic Materials
The performances of hybrid organic–inorganic
photovoltaics
composed of conjugated polymers and metal oxides are generally limited
by poor electronic coupling at hybrid interfaces. In this study, physicochemical
interactions and bonding at the organic–inorganic interfaces
are promoted by incorporating organoruthenium dye molecules into self-assembled
mesostructured conjugated polymer–titania composites. These
materials are synthesized from solution in the presence of surfactant
structure-directing agents (SDA) that solubilize and direct the nanoscale
compositions and structures of the conjugated polymer, dye, and inorganic
precursor species. Judicious selection of the SDA and dye species,
in particular, exploits interactions that direct the dye species to
the inorganic–organic interfaces, leading to significantly
enhanced electronic coupling, as well as increased photoabsorption
efficiency. This is demonstrated for the hydrophilic organoruthenium
dye N3, used in conjunction with alkyleneoxide triblock copolymer
SDA, polythiophene conjugated polymer, and titania species, in which
the N3 dye species are localized in molecular proximity to and interact
strongly with the titania framework, as established by solid-state
NMR spectroscopy. In contrast, a closely related but more hydrophobic
organoruthenium dye, Z907, is shown to interact more weakly with the
titania framework, yielding significantly lower photocurrent generation.
The strong SDA-directed N3-TiO<sub><i>x</i></sub> interactions
result in a significant reduction of the lifetime of the photoexcited
state and enhanced macroscopic photocurrent generation in photovoltaic
devices. This study demonstrates that multicomponent self-assembly
can be harnessed for the fabrication of hierarchical materials and
devices with nanoscale control of chemical compositions and surface
interactions to improve photovoltaic properties
Diffusive and ballistic transport in thin InSb nanowire devices using a few-layer-graphene-AlO x gate
Quantum devices based on InSb nanowires (NWs) are a prime candidate system for realizing and exploring topologically-protected quantum states and for electrically-controlled spin-based qubits. The influence of disorder on achieving reliable quantum transport regimes has been studied theoretically, highlighting the importance of optimizing both growth and nanofabrication. In this work, we consider both aspects. We developed InSb NW with thin diameters, as well as a novel gating approach, involving few-layer graphene and atomic layer deposition-grown AlO _x . Low-temperature electronic transport measurements of these devices reveal conductance plateaus and Fabry–Pérot interference, evidencing phase-coherent transport in the regime of few quantum modes. The approaches developed in this work could help mitigate the role of material and fabrication-induced disorder in semiconductor-based quantum devices