507 research outputs found
How much are senior UK public health professionals taught about mental health?
Directors, consultants and specialists in public mental health play a major role in developing and implementing local and national mental health policy. This study focuses on what academic training they receive about mental health via Master of Public Health (MPH) programmes. If you are a clinical psychologist involved in teaching on a MPH course we would be interested in hearing about your experiences
Evidence for contact delocalization in atomic scale friction
We analyze an advanced two-spring model with an ultra-low effective tip mass
to predict nontrivial and physically rich 'fine structure' in the atomic
stick-slip motion in Friction Force Microscopy (FFM) experiments. We
demonstrate that this fine structure is present in recent, puzzling
experiments. This shows that the tip apex can be completely or partially
delocalized, thus shedding new light on what is measured in FFM and, possibly,
what can happen with the asperities that establish the contact between
macroscopic sliding bodies.Comment: 4 pages text and 3 figure
Designing for a Living? Income Determinants Among Firm Founders in the Dutch Design Sector
The geographical distribution of leadership in globalized clinical trials
Background Pharmaceutical trials are mainly initiated by sponsors and investigators in the United States, Western Europe and Japan. However, more and more patients are enrolled in Central and Eastern Europe, Latin America and Asia. The involvement of patients in new geographical settings raises questions about scientific and ethical integrity, especially when experience with those settings is lacking at the level of trial management. We therefore studied to what extent the geographical shift in patient enrolment is anticipated in the composition of trial management teams using the author nationalities on the primary outcome publication as an indicator of leadership. Methods and Findings We conducted a cohort-study among 1,445 registered trials in www.clinicaltrials.gov that could be matched with a primary outcome publication using clinical trial registry numbers listed in publications. The name of the sponsor and the enrolment countries were extracted from all registrations. The author-addresses of all authors were extracted from the publications. We searched the author-address of all publications to determine whether enrolment countries and sponsors listed on registrations also appeared on a matched publication. Of all sponsors, 80.1% were listed with an author-address on the publication. Of all enrolment countries, 50.3% appeared with an author-address on the publication. The listing of enrolment countries was especially low for industry-funded trials (39.9%) as compared to government (90.4%) and not-for-profit funding (93.7%). We found that listing of enrolment countries in industry-funded trials was higher for traditional research locations such as the United States (98.2%) and Japan (72.0%) as compared to nontraditional research locations such as Poland (27.3%) and Mexico (14.1%). Conclusions Despite patient enrolment efforts, the involvement of researchers from nontraditional locations in trial management as measured by their contribution to manuscript writing is modest. This division of labor has significant implications for the scientific and ethical integrity of global clinical research
Основні властивості джерел конституційного права України
Аналізуються проблеми системи джерел конституційного права України, висвітлюються особливості як системи джерел конституційного права України в цілому, так і окремих її складових. Підкреслюється необхідність наукового обґрунтування юридичної природи та системно-ієрархічних зв’язків між складовими системи джерел конституційного права.Аналтизуються проблемы системы источников конституционного права Украины, рассматриваются особенности системы источников конституционного права Украины в целом и отдельных её составляющих. Подчеркивается необходимость научного обоснования юридической природы и системно-иерархических взаимоотношений между осотавляющими системы конституционного права Украины.The author devoted to the study of selected problems of the system of sources of Ukrainian constitutional law, covers in detail the peculiarities of the system of sources of Ukrainian constitutional law as a whole and its components
Directed transient long-range transport in a slowly driven Hamiltonian system of interacting particles
We study the Hamiltonian dynamics of a one-dimensional chain of linearly
coupled particles in a spatially periodic potential which is subjected to a
time-periodic mono-frequency external field. The average over time and space of
the related force vanishes and hence, the system is effectively without bias
which excludes any ratchet effect. We pay special attention to the escape of
the entire chain when initially all of its units are distributed in a potential
well. Moreover for an escaping chain we explore the possibility of the
successive generation of a directed flow based on large accelerations. We find
that for adiabatic slope-modulations due to the ac-field transient long-range
transport dynamics arises whose direction is governed by the initial phase of
the modulation. Most strikingly, that for the driven many particle Hamiltonian
system directed collective motion is observed provides evidence for the
existence of families of transporting invariant tori confining orbits in
ballistic channels in the high dimensional phase spaces
Roughening of close-packed singular surfaces
An upper bound to the roughening temperature of a close-packed singular
surface, fcc Al (111), is obtained via free energy calculations based on
thermodynamic integration using the embedded-atom interaction model. Roughening
of Al (111) is predicted to occur at around 890 K, well below bulk melting (933
K), and it should therefore be observable, save for possible kinetic hindering.Comment: RevTeX 4 pages, embedded figure
Deep learning-based post-processing of real-time MRI to assess and quantify dynamic wrist movement in health and disease
While morphologic magnetic resonance imaging (MRI) is the imaging modality of choice for the evaluation of ligamentous wrist injuries, it is merely static and incapable of diagnosing dynamic wrist instability. Based on real-time MRI and algorithm-based image post-processing in terms of convolutional neural networks (CNNs), this study aims to develop and validate an automatic technique to quantify wrist movement. A total of 56 bilateral wrists (28 healthy volunteers) were imaged during continuous and alternating maximum ulnar and radial abduction. Following CNN-based automatic segmentations of carpal bone contours, scapholunate and lunotriquetral gap widths were quantified based on dedicated algorithms and as a function of wrist position. Automatic segmentations were in excellent agreement with manual reference segmentations performed by two radiologists as indicated by Dice similarity coefficients of 0.96 ± 0.02 and consistent and unskewed Bland–Altman plots. Clinical applicability of the framework was assessed in a patient with diagnosed scapholunate ligament injury. Considerable increases in scapholunate gap widths across the range-of-motion were found. In conclusion, the combination of real-time wrist MRI and the present framework provides a powerful diagnostic tool for dynamic assessment of wrist function and, if confirmed in clinical trials, dynamic carpal instability that may elude static assessment using clinical-standard imaging modalities
World citation and collaboration networks: uncovering the role of geography in science
Modern information and communication technologies, especially the Internet,
have diminished the role of spatial distances and territorial boundaries on the
access and transmissibility of information. This has enabled scientists for
closer collaboration and internationalization. Nevertheless, geography remains
an important factor affecting the dynamics of science. Here we present a
systematic analysis of citation and collaboration networks between cities and
countries, by assigning papers to the geographic locations of their authors'
affiliations. The citation flows as well as the collaboration strengths between
cities decrease with the distance between them and follow gravity laws. In
addition, the total research impact of a country grows linearly with the amount
of national funding for research & development. However, the average impact
reveals a peculiar threshold effect: the scientific output of a country may
reach an impact larger than the world average only if the country invests more
than about 100,000 USD per researcher annually.Comment: Published version. 9 pages, 5 figures + Appendix, The world citation
and collaboration networks at both city and country level are available at
http://becs.aalto.fi/~rajkp/datasets.htm
Temperature dependent surface relaxations of Ag(111)
The temperature dependent surface relaxation of Ag(111) is calculated by
density-functional theory. At a given temperature, the equilibrium geometry is
determined by minimizing the Helmholtz free energy within the quasiharmonic
approximation. To this end, phonon dispersions all over the Brillouin zone are
determined from density-functional perturbation theory. We find that the
top-layer relaxation of Ag(111) changes from an inward contraction (-0.8 %) to
an outward expansion (+6.3%) as the temperature increases from T=0 K to 1150 K,
in agreement with experimental findings. Also the calculated surface phonon
dispersion curves at room temperature are in good agreement with helium
scattering measurements. The mechanism driving this surface expansion is
analyzed.Comment: 6 pages, 7 figures, submitted to Phys. Rev. B (May 1998). Other
related publications can be found at
http://www.rz-berlin.mpg.de/th/paper.htm
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