73,088 research outputs found
Microwave Power Transmission Workshop summary
The assumptions, methodologies, and conclusions of the NASA SPS studies were assessed and criticized to identify critical issues and to make recommendations for follow-on works. An assessment of the following items was made: beam forming and control, microwave amplifiers, radiating elements, and the rectenna. It was concluded that top priority should be given to determining an upper limit for permissible microwave power density which can be sent through the ionosphere
Education for citizenship: the Joseph Rowntree Charitable Trust and the educational settlement movement
No abstract available
The effects of storage conditions on viability of Clostridium difficile vegetative cells and spores and toxin activity in human faeces
AIMS: Clostridium difficile is a common nosocomial pathogen and as such diagnostic and research
methods may necessitate storage of faecal specimens for long periods, followed by subsequent
re-examination. This study investigated the effects of storage conditions upon the viability of this organism
and its toxin.
METHODS: Three genotypically distinct strains of C difficile (two clinical isolates including the UK epidemic
strain, and an environmental isolate) were grown anaerobically at 37°C for 72 hours in a pool
of five faecal emulsions. Aliquots of each emulsion were stored at either -20°C (frozen) or 4°C (refrigerated).
Emulsions were assayed for viable cells, spores, and cytotoxin titre before storage and at days
1, 3, 5, 7, 14, 28, and 56. An aliquot of each emulsion was also removed, assayed, and replaced in
storage at each time point to investigate the effects of multiple freezing/refrigeration/thawing .
RESULTS: Neither storage temperature nor multiple cycles of refrigeration/freezing and thawing
adversely affected the viability of C difficilevegetative cells or spores. Single and multiple exposures of
samples to 4°C had little effect upon the C difficile toxin titre. Toxin titres of multiply frozen and thawed
faeces became significantly lower than for refrigerated faeces (p < 0.01) by day 5 of the experiment
in two of the three strains, and in all strains by day 28. Toxin titres of singly frozen faeces became significantly
lower than for refrigerated faeces (p < 0.01) by day 56 of the experiment in two of the three
strains.
CONCLUSION: Storage temperature and multiple cycles of freezing (refrigeration)/thawing had minimal
effects upon the viability of C difficile or its spores. Storage at 4°C has no discernible effect on C difficile
cytotoxin. However, storage at -20°C has a detrimental effect upon C difficile cytotoxin, and multiple
cycles of freezing and thawing may further adversely effect toxin titres
The Challenges Posed by Globalization for Economic Liberalization in Two Asian Transitional Countries: Laos and Vietnam
globalization backlash, foreign direct investment, East Asia
Brain food for babies
How does a mother supply a key building block of the brain required for neurodevelopment to her fetus in pregnancy? The critical requirement of docosahexaenoic acid (DHA) for fetal brain development, and the poor efficiency of its synthesis in humans, is a tricky metabolic problem to be overcome in pregnant women. Supplying this unique fatty acid to the fetus requires exquisite specificity and timing, processes that can unravel in disease conditions such as pre-eclampsia
Maternal plasma docosahexaenoic acid (DHA) concentrations increase at the critical time of neural tube closure
No abstract available
Implementation of pattern-recognition algorithms derived from olfactory information processing
Nonlinear brain dynamics as macroscopic manifestation of underlying many-body field dynamics
Neural activity patterns related to behavior occur at many scales in time and
space from the atomic and molecular to the whole brain. Here we explore the
feasibility of interpreting neurophysiological data in the context of many-body
physics by using tools that physicists have devised to analyze comparable
hierarchies in other fields of science. We focus on a mesoscopic level that
offers a multi-step pathway between the microscopic functions of neurons and
the macroscopic functions of brain systems revealed by hemodynamic imaging. We
use electroencephalographic (EEG) records collected from high-density electrode
arrays fixed on the epidural surfaces of primary sensory and limbic areas in
rabbits and cats trained to discriminate conditioned stimuli (CS) in the
various modalities. High temporal resolution of EEG signals with the Hilbert
transform gives evidence for diverse intermittent spatial patterns of amplitude
(AM) and phase modulations (PM) of carrier waves that repeatedly re-synchronize
in the beta and gamma ranges at near zero time lags over long distances. The
dominant mechanism for neural interactions by axodendritic synaptic
transmission should impose distance-dependent delays on the EEG oscillations
owing to finite propagation velocities. It does not. EEGs instead show evidence
for anomalous dispersion: the existence in neural populations of a low velocity
range of information and energy transfers, and a high velocity range of the
spread of phase transitions. This distinction labels the phenomenon but does
not explain it. In this report we explore the analysis of these phenomena using
concepts of energy dissipation, the maintenance by cortex of multiple ground
states corresponding to AM patterns, and the exclusive selection by spontaneous
breakdown of symmetry (SBS) of single states in sequences.Comment: 31 page
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