3,804 research outputs found

    Further investigation of the interference minimums in the low-frequency electromagnetic fields produced by a submerged vertical magnetic dipole

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    The quasi-static electromagnetic fields generated along the sea surface by a submerged vertical magnetic dipole are evaluated numerically using exact expressions and the results are plotted in a parametric form for source depths varying from 2 to 14 seawater skin depths δ. The curves show that there is a minimum in the amplitude of the vertical component of the magnetic field for horizontal distances from the source in the range 9–14δ and for dipole depths ranging from 2 to 8δ, with the deepest minimum occurring at a horizontal distance of pmin ≃ 11.07δ when the dipole is at a critical depth of dc ≃ 4.22δ. There also exists a similar minimum point in the variation along the surface of the amplitude of the total electric field for horizontal distances from the source in the range 10–20δ and dipole depths ranging from 4 to 23δ, with the deepest minimum occurring at a horizontal distance of pmin ≃ 12.95δ when the dipole is at a depth of dc ≃ 9.38δ. Both minimums are due to the strong destructive interference between the direct and the lateral wave components of the fields. No such minimum point exists for the variation of the amplitude of the horizontal component of the magnetic field

    Community experiences of organised crime in Scotland

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    The research explored community experiences of serious organised crime in Scotland (SOC). The report provides information on the nature and extent of the impact of SOC on everyday life in the community, as well as offering suggestions for policy development. The study sought to answer the following questions: 1)What are the relationships that exist between SOC and communities in Scotland? 2)What are the experiences and perceptions of residents, stakeholders and organisations of the scope and nature of SOC within their local area? and 3)How does SOC impact on community wellbeing, and to what extent can the harms associated with SOC be mitigated

    ULF/ELF electromagnetic fields produced in a conducting medium of infinite extent by linear current sources of infinite length

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    A previous analysis of a linear current source of finite length embedded in a conducting medium of infinite extent is extended to linear current sources of (1) infinite length and (2) semi-infinite length. Electric and magnetic field expressions are derived, and the results are numerically evaluated for frequencies in the ULF/ELF bands. For convenience, some of the results are presented in a dimensionless form. A comparison is made between the electromagnetic fields produced by linear current sources of finite and infinite length, and it is shown that there is a relative enhancement in the electric field near the source of finite length. It is also found that an optimum frequency exists for the electric field produced by a linear current source of infinite length at which the field amplitude is a maximum at a fixed observation point. Some practical applications of our results are suggested

    ULF/ELF electromagnetic fields generated along the sea floor interface by a straight current source of infinite length

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    Propagation of ULF/ELF electromagnetic fields along the seafloor interface (assumed to be a plane boundary separating two semi-infinite conducting media) is considered. Earlier expressions for the electromagnetic fields generated by a straight current source of infinite length are applied to the sea/seabed interface. The field components are calculated numerically and are compared to the field components in seawater of infinite extent. At the seafloor boundary, the fields can propagate longer distances because of the lower seabed conductivities. The new horizontal component of the magnetic field generated as a result of the existence of the sea/seabed interface becomes larger than the vertical component of the magnetic field at large distances; it is also more sensitive to the conductivity of the seabed at low frequencies. The results indicate that there is an optimal frequency at which two of the field components have a maximum field intensity at a certain distance from the source. Some practical applications are discussed

    Formation and removal of alkylthiolate self-assembled monolayers on gold in aqueous solutions

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    We report the development of novel reagents and approaches for generating recyclable biosensors. The use of aqueous media for the formation of protein binding alkylthiolate monolayers on Au surfaces results in accelerated alkylthiolate monolayer formation and improvement in monolayer integrity as visualized by fluorescence microscopy and CV techniques. We have also developed an electrocleaning protocol that is compatible with microfluidics devices, and this technique serves as an on-chip method for cleaning Au substrates both before and after monolayer formation. The techniques for the formation and dissociation of biotinylated SAMs from aqueous solvents reported here may be applied towards the development of Au-based sensor devices and microfluidics chips in the future. A potential use of these devices includes the specific capture and triggered release of target cells, proteins, or small molecules from liquid samples

    The Automatic Real-Time GRB Pipeline of the 2-m Liverpool Telescope

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    The 2-m Liverpool Telescope (LT), owned by Liverpool John Moores University, is located in La Palma (Canary Islands) and operates in fully robotic mode. In 2005, the LT began conducting an automatic GRB follow-up program. On receiving an automatic GRB alert from a Gamma-Ray Observatory (Swift, INTEGRAL, HETE-II, IPN) the LT initiates a special override mode that conducts follow-up observations within 2-3 min of the GRB onset. This follow-up procedure begins with an initial sequence of short (10-s) exposures acquired through an r' band filter. These images are reduced, analyzed and interpreted automatically using pipeline software developed by our team called "LT-TRAP" (Liverpool Telescope Transient Rapid Analysis Pipeline); the automatic detection and successful identification of an unknown and potentially fading optical transient triggers a subsequent multi-color imaging sequence. In the case of a candidate brighter than r'=15, either a polarimetric (from 2006) or a spectroscopic observation (from 2007) will be triggered on the LT. If no candidate is identified, the telescope continues to obtain z', r' and i' band imaging with increasingly longer exposure times. Here we present a detailed description of the LT-TRAP and briefly discuss the illustrative case of the afterglow of GRB 050502a, whose automatic identification by the LT just 3 min after the GRB, led to the acquisition of the first early-time (< 1 hr) multi-color light curve of a GRB afterglow.Comment: PASP, accepted (8 pages, 3 figures

    Interacting Supernovae: Types IIn and Ibn

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    Supernovae (SNe) that show evidence of strong shock interaction between their ejecta and pre-existing, slower circumstellar material (CSM) constitute an interesting, diverse, and still poorly understood category of explosive transients. The chief reason that they are extremely interesting is because they tell us that in a subset of stellar deaths, the progenitor star may become wildly unstable in the years, decades, or centuries before explosion. This is something that has not been included in standard stellar evolution models, but may significantly change the end product and yield of that evolution, and complicates our attempts to map SNe to their progenitors. Another reason they are interesting is because CSM interaction is an efficient engine for making bright transients, allowing super-luminous transients to arise from normal SN explosion energies, and allowing transients of normal SN luminosities to arise from sub-energetic explosions or low radioactivity yield. CSM interaction shrouds the fast ejecta in bright shock emission, obscuring our normal view of the underlying explosion, and the radiation hydrodynamics of the interaction is challenging to model. The CSM interaction may also be highly non-spherical, perhaps linked to binary interaction in the progenitor system. In some cases, these complications make it difficult to definitively tell the difference between a core-collapse or thermonuclear explosion, or to discern between a non-terminal eruption, failed SN, or weak SN. Efforts to uncover the physical parameters of individual events and connections to possible progenitor stars make this a rapidly evolving topic that continues to challenge paradigms of stellar evolution.Comment: Final draft of a chapter in the "SN Handbook". Accepted. 25 pages, 3 fig

    Early GRB Optical and Infrared Afterglow Observations with the 2-m Robotic Liverpool Telescope

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    We present the first optical observations of a Gamma Ray Burst (GRB) afterglow using the 2-m robotic Liverpool Telescope (LT), which is owned and operated by Liverpool John Moores University and situated on La Palma. We briefly discuss the capabilities of LT and its suitability for rapid follow-up observations of early optical and infrared GRB light curves. In particular, the combination of aperture, site, instrumentation and rapid response (robotic over-ride mode aided by telescope's rapid slew and fully-opening enclosure) makes the LT ideal for investigating the nature of short bursts, optically-dark bursts, and GRB blast-wave physics in general. We briefly describe the LT's key position in the RoboNet-1.0 network of robotic telescopes. We present the LT observations of GRB041006 and use its gamma-ray properties to predict the time of the break in optical light curve, a prediction consistent with the observations.Comment: 4 pages, 1 figure, accepted for publication in Il nuovo cimento (4th Workshop Gamma-Ray Bursts in the Afterglow Era, Rome, 18-22 October 2004

    A Massive Progenitor of the Luminous Type IIn Supernova 2010jl

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    The bright, nearby, recently discovered supernova SN2010jl is a member of the rare class of relatively luminous Type~IIn events. Here we report archival HST observations of its host galaxy UGC5189A taken roughly 10yr prior to explosion, as well as early-time optical spectra of the SN. The HST images reveal a bright, blue point source at the position of the SN, with an absolute magnitude of -12.0 in the F300W filter. If it is not just a chance alignment, the source at the SN position could be (1) a massive young (less than 6 Myr) star cluster in which the SN resided, (2) a quiescent, luminous blue star with an apparent temperature around 14,000K, (3) a star caught during a bright outburst akin to those of LBVs, or (4) a combination of option 1 and options 2 or 3. Although we cannot confidently choose between these possibilities with the present data, any of them imply that the progenitor of SN2010jl had an initial mass above 30Msun. This reinforces mounting evidence that many SNe IIn result from very massive stars, that massive stars can produce visible SNe without collapsing quietly to black holes, and that massive stars can retain their H envelopes until shortly before explosion. Standard stellar evolution models fail to account for these observed properties.Comment: 6 pages, 4 figures, submitted to Ap

    A Three Monoclonal Antibody Combination Potently Neutralizes Multiple Botulinum Neurotoxin Serotype E Subtypes.

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    Human botulism is most commonly caused by botulinum neurotoxin (BoNT) serotypes A, B, and E. For this work, we sought to develop a human monoclonal antibody (mAb)-based antitoxin capable of binding and neutralizing multiple subtypes of BoNT/E. Libraries of yeast-displayed single chain Fv (scFv) antibodies were created from the heavy and light chain variable region genes of humans immunized with pentavalent-toxoid- and BoNT/E-binding scFv isolated by Fluorescence-Activated Cell Sorting (FACS). A total of 10 scFv were isolated that bound one or more BoNT/E subtypes with nanomolar-level equilibrium dissociation constants (KD). By diversifying the V-regions of the lead mAbs and selecting for cross-reactivity, we generated three scFv that bound all four BoNT/E subtypes tested at three non-overlapping epitopes. The scFvs were converted to IgG that had KD values for the different BoNT/E subtypes ranging from 9.7 nM to 2.28 pM. An equimolar combination of the three mAbs was able to potently neutralize BoNT/E1, BoNT/E3, and BoNT/E4 in a mouse neutralization assay. The mAbs have potential utility as therapeutics and as diagnostics capable of recognizing multiple BoNT/E subtypes. A derivative of the three-antibody combination (NTM-1633) is in pre-clinical development with an investigational new drug (IND) application filing expected in 2018
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