Bestimmung der Aktivitätsverteilung in Gebinden mit geringfügig radioaktivem, Material unter Verwendung großflächiger, unkollimierter, feststehender Gamma-Szintillationsdetektoren

Die Verwendung von großflächigen Gamma-Detektoren zeichnet sich durch hohe Effektivität und damit geringe Messzeit aus. Dagegen sind mit ihnen keine hohen Ortsauflösungen bei der Rekonstruktion der Aktivitätsverteilung möglich. Zur Untersuchung der Rekonstruierbarkeit unbekannter Aktivitätsverteilungen werden zwei in der Tomographie gebräuchliche Verfahren verglichen, ein algebraisches (iterativ) und ein analytisches (gefilterte Rückprojektion). Beide Verfahren erbringen qualitativ ähnliche Ergebnisse. Reale Aktivitätsverteilungen werden nach beiden Verfahren zufriedenstellend rekonstruiert

Role of contrast-enhanced ultrasound (CEUS) in paediatric practice: an EFSUMB position statement

The use of contrast-enhanced ultrasound (CEUS) in adults is well established in many different areas, with a number of current applications deemed off-label, but the use supported by clinical experience and evidence. Paediatric CEUS is also an off-label application until recently with approval specifically for assessment of focal liver lesions. Nevertheless there is mounting evidence of the usefulness of CEUS in children in many areas, primarily as an imaging technique that reduces exposure to radiation, iodinated contrast medium and the patient-friendly circumstances of ultrasonography. This position statement of the European Federation of Societies in Ultrasound and Medicine (EFSUMB) assesses the current status of CEUS applications in children and makes suggestions for further development of this technique

Characterization of the Metal Fused Filament Fabrication Process for Manufacturing of Pure Copper Inductors

This work presents a comprehensive investigation into the optimization of critical process parameters associated with metal fused filament fabrication (Metal-FFF) for the production of copperbased components. The study focused on three different commercial and one self-manufactured filament, each with unique chemical compositions. These filaments were systematically optimized and the density was characterized for all processing steps, as well as the electrical conductivity on the specimen scale. Remarkably, two of the studied filaments exhibited exceptional properties after sintering with forming gas (up to 94% density and 55.75MS/m electrical conductivity), approaching the properties measured for established manufacturing methods like metal injection molding. Finally, the research was extended to component-scale applications, demonstrating the successful fabrication of inductors with integrated cooling channels. These components exhibited water tightness and were used in induction hardening experiments, validating the practical utility of the optimized Metal-FFF process. In summary, the results show great promise in advancing the utilization of Metal

La comunicazione politica nei manifesti della campagna elettorale 2008

Il presente lavoro si propone di prendere in esame i criteri comunicativi adottati dai principali partiti nei manifesti elettorali prodotti in occasione delle elezioni politiche del 2008. Dopo una breve parte propedeutica sulla comunicazione politica ed un excursus sulla storia del manifesto politico si procede ad analizzare dettagliatamente i manifesti elettorali dei principali partiti: Il Popolo della Libertà, Alleanza Nazionale, Lega Nord, La Destra, Partito Democratico, Italia dei Valori, Unione di Centro, Partito Socialista, La Sinistra, l’Arcobaleno. L’analisi si basa sui manifesti che è stato possibile rintracciare sui siti internet dei partiti e nella Rete in generale. I principali campi di indagine sono: il tipo di immagini scelte dai partiti a suffragio delle loro proposte politiche, la grafica, i colori e il lessico adottato per attirare l’attenzione dell’elettore e convincerlo ad orientare il suo voto in una determinata direzion

Emotion dysregulation and integration of emotion-related brain networks affect intraindividual change in ADHD severity throughout late adolescence

Contains fulltext : 244227.pdf (Publisher’s version ) (Open Access

Polygenic risk scores for antisocial behavior in relation to amygdala morphology across an attention deficit hyperactivity disorder case-control sample with and without disruptive behavior

Antisocial and aggressive behaviors show considerable heritability and are central to disruptive behavior disorders (DBDs), but are also frequently observed in attention deficit hyperactivity disorder (ADHD). While the amygdala is implicated as a key neural structure, it remains unclear whether common genetic variants underlie this brain-behavior association. We hypothesized that polygenic (risk) scores for antisocial and aggressive behaviors (ASB-PRS) would be related to amygdala morphology. Using the Broad Antisocial Behavior Consortium genome-wide association study (GWAS; mostly population based cohorts), we calculated ASB-PRS in the NeuroIMAGE I ADHD case-control sample with varying levels of DBD symptomatology (n=679 from 379 families, aged 7 - 29). We first investigated associations of several ASB-PRS p value thresholds with the presence of DBD symptoms and self-reported antisocial behavior (ASB) to determine the threshold for further analyses. This PRS was then related to amygdala volume and shape using regression and vertex-wise analyses. Our results showed associations of ASB-PRS with the presence of DBD symptoms, self-reported ASB, and left basolateral amygdala shape, independent of ADHD symptom severity and ADHD-PRS, with a relative outward displacement of the vertices. No associations of ASB-PRS, DBD symptoms or self-reported ASB with amygdala volume were found. Our results indicate that genetic risk for antisocial and aggressive behaviors is related to amygdala shape alterations, and point to genetic sharing across different DBD and ASB and aggression-related phenotypes as a spectrum of genetically related quantitative traits. Additionally, our findings support the utility of vertex-based shape analyses in genetic studies of ASB, aggression, and DBDs