156 research outputs found

    Una Herramienta para la estimación del esfuerzo del estudiante de grado en ingeniería informática

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    En el marco de las nuevas titulaciones de Grado en Ingeniería Informática, resulta muy conveniente establecer algún tipo de mecanismo que nos permita recoger información sobre la dedicación real de los estudiantes a nuestras asignaturas. A nivel de asignatura, esta información puede servir al profesorado para determinar el grado de acierto de su planificación temporal inicial. A un nivel más global, los datos recogidos proporcionan a los coordinadores de curso una idea de la carga total a la que está sometido el estudiante, y contribuyen a la identificación de posibles picos (o valles) de trabajo durante el cuatrimestre. En este trabajo se describe la puesta en marcha de un sistema, basado en encuestas, para el conocimiento del esfuerzo de los estudiantes de Grado en Ingeniería Informática de la Escuela Superior de Ingeniería Informática de Albacete. También se presentan y analizan algunos de los resultados obtenidos durante el curso académico 2012/13.SUMMARY -- In the framework of new degrees in Computer Science, it is desirable to establish some mechanism to let us collect some information about our students' commitment to our courses. On the subject level, this information may be useful for the teaching staff to determine the degree of success of this initial temporary planning. In a high level point of view, the data collected provide the course coordination with an idea of the total workload of students and it contributes to identify potential peaks (or valleys) of work throughout the semester. This work presents a surveybased system to obtain and register the efforts of our Computer Engineering students from the School of Computer Engineering of Albacete. It also introduces and discusses some of the results obtained during the academic year 2012/13

    Electrodeposition of Co-Sb Thick Films and their Thermoelectric Properties in DMSO

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    Póster presentado en la 11th European Conference on Thermoelectrics (ECT2013), celebrada en Noordwijk (Holanda) del 18 al 20 de noviembre de 2013.In the last decade there has been an increasingly interest in the Skutterudites in the field of thermoelectricity 1. This interest is based on the fact that the highest performance of this material happens at 400ºC, which makes it ideal for multiple applications as energy harvesting devices. Generally, most of the actual compounds working under these conditions are unstable or presents a low figure of merit 2. However, Skutterudites have usually good values of the power factor, but also they offer the possibility of an enhancement of their efficiency due to the reduction of the thermal conductivity via doping the structure 3 or filling of the voids 3 of the structure with heavy atoms. Nevertheless, to obtain the right phase by electrodeposition is still not a solve question. 4 This work deals the electrodeposition of Skutterudite (CoSb3). We have been able to grow CoSb3 films via electrochemical deposition in an organic solvent (DMSO). After studying different parameters such as temperature, stirring, time of deposition or potential, we have been able to obtain quite homogeneously films with 1:3 ratio. For the first time, thermoelectric properties have been measured in different labs, to measure the Seebeck coefficient and electrical conductivity of the films in plane, and using a Seebeck microprobe system, to measure and make a map of the Seebeck coefficient in cross-plane. We determine the Seebeck coefficient to be -12 µV/K in plane and -37 µV/K out of plane, and an electrical conductivity of around 9 S/cm in plane.The research work is supported by the European Commission under FP7-NEXTEC project, Grant # 263167 [FP7/2011-2013].Peer Reviewe

    Efficacy and Safety of a Novel Submucosal Injection Solution for Resection of Gastrointestinal Lesions

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    Endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) are minimally invasive and efficient techniques for the removal of gastrointestinal (GI) mucosal polyps. In both techniques, submucosal injection solutions are necessary for complete effectiveness and safety during the intervention to be obtained. The main objective of this study was to evaluate the efficacy and safety of a new sterile submucosal injection solution for EMR/ESD used within a clinical protocol in patients with intestinal polyps. We carried out a prospective study between 2016 and 2017 with patients who attended the Endoscopy Consultation—Digestive Department of Primary Hospital. Patients were selected for EMR/ESD after the application of clinical protocols. Thirty-six patients were selected (≥ 66 years with comorbidities and risk factors). Lesions were located mainly in the colon. Our solution presented an intestinal lift ≥ 60 min in EMR/ESD and a high expansion of tissue, optimum viscosity, and subsequent complete resorption. The genes S100A9 and TP53 presented an expression increase in the distal regions. TP53 and PCNA were the only genes whose expression was increased in polyp specimens vs. the surrounding tissue at the mRNA level. In EMR/ESD, our solution presented a prolonged effect at the intestinal level during all times of the intervention. Thus, our solution seems be an effective and safe alternative in cases of flat lesions in both techniques.Study co-financed by the Junta de Andalucia (PIN-0479-2016, CTS676, CTS235, CTS164), the Ministry of Economy and Competitivity, Spain (SAF2017-88457-R, AGL2017-85270-R), Nakafarma S.L and CIBERehd is funded by Instituto de Salud Carlos III, Spain. The sponsors had no role in the design, execution, interpretation, or writing of the study

    Antibody persistence and booster responses 24-36 months after different 4CMenB vaccination schedules in infants and children: A randomised trial.

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    This phase IIIb, open-label, multicentre, extension study (NCT01894919) evaluated long-term antibody persistence and booster responses in participants who received a reduced 2 + 1 or licensed 3 + 1 meningococcal serogroup B vaccine (4CMenB)-schedule (infants), or 2-dose catch-up schedule (2-10-year-olds) in parent study NCT01339923. Children aged 35 months to 12 years (N = 851) were enrolled. Follow-on participants (N = 646) were randomised 2:1 to vaccination and non-vaccination subsets; vaccination subsets received an additional 4CMenB dose. Newly enrolled vaccine-naïve participants (N = 205) received 2 catch-up doses, 1 month apart (accelerated schedule). Antibody levels were determined using human serum bactericidal assay (hSBA) against MenB indicator strains for fHbp, NadA, PorA and NHBA. Safety was also evaluated. Antibody levels declined across follow-on groups at 24-36 months versus 1 month post-vaccination. Antibody persistence and booster responses were similar between infants receiving the reduced or licensed 4CMenB-schedule. An additional dose in follow-on participants induced higher hSBA titres than a first dose in vaccine-naïve children. Two catch-up doses in vaccine-naïve participants induced robust antibody responses. No safety concerns were identified. Antibody persistence, booster responses, and safety profiles were similar with either 2 + 1 or 3 + 1 vaccination schedules. The accelerated schedule in vaccine-naïve children induced robust antibody responses.Novartis Vaccines DivisionGlaxoSmithKline Biologicals S

    Hypertension is related to the degradation of dietary frying oils

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    [Background]: The family kitchen resembles an uncontrolled laboratory experiment, and some discrepancies in the relation between the risk of hypertension and dietary fat may be partly due to the manipulation to which the fats were subjected. [Objective]: We investigated whether deterioration in the quality of the cooking oils in the family household contributes to the risk of high blood pressure. [Design]: The study was cross-sectional. Anthropometric measurements were obtained for 1226 persons aged 18–65 y who were selected randomly from the municipal census of Pizarra, Spain. An oral-glucose-tolerance test was given to 1020 of these persons. Samples of the cooking oil being used were taken from the kitchens of a random subset of 538 persons. The concentrations of polar compounds and polymers were used as markers of the deterioration of the oils. The strength of association between variables was measured by calculating the odds ratio from logistic models. [Results]: Hypertension was strongly associated with obesity and was influenced by sex, diabetes, and age. The presence of excess polar compounds in the cooking oil and the use of sunflower oil were related to the risk of hypertension, whereas the concentration of monounsaturated fatty acids in the serum phospholipids was negatively related to this risk. These associations remained after inclusion in the models of age, sex, obesity, and the presence of carbohydrate metabolism disorder. [Conclusions]: The risk of hypertension is positively and independently associated with the intake of cooking oil polar compounds and inversely related to blood concentrations of monounsaturated fatty acids

    Brief cognitive assessment instruments in schizophrenia and bipolar patients, and healthy control subjects: A comparison study between the Brief Cognitive Assessment Tool for Schizophrenia (B-CATS) and the Screen for Cognitive Impairment in Psychiatry (SCIP)

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    Cognitive impairment in schizophrenia and psychosis is ubiquitous and acknowledged as a core feature of clinical expression, pathophysiology, and prediction of functioning. However, assessment of cognitive functioning is excessively time-consuming in routine practice, and brief cognitive instruments specific to psychosis would be of value. Two screening tools have recently been created to address this issue, i.e., the Brief Cognitive Assessment Tool for Schizophrenia (B-CATS) and the Screen for Cognitive Impairment in Psychiatry (SCIP). The aim of this research was to examine the comparative validity of these two brief instruments in relation to a global cognitive score. 161 patients with psychosis (96 patients diagnosed with schizophrenia and 65 patients diagnosed with bipolar disorder) and 76 healthy control subjects were tested with both instruments to examine their concurrent validity relative to a more comprehensive neuropsychological assessment battery. Scores from the B-CATS and the SCIP were highly correlated in the three diagnostic groups, and both scales showed good to excellent concurrent validity relative to a Global Cognitive Composite Score (GCCS) derived from the more comprehensive examination. The SCIP-S showed better predictive value of global cognitive impairment than the B-CATS. Partial and semi-partial correlations showed slightly higher percentages of both shared and unique variance between the SCIP-S and the GCCS than between the B-CATS and the GCCS. Brief instruments for assessing cognition in schizophrenia and bipolar disorders, such as the SCIP-S and B-CATS, seem to be reliable and promising tools for use in routine clinical practice
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