130 research outputs found
Editorial to the special issue on "Advances in statistical modelling, methods and applications"
Indagine sismica a riflessione ad alta risoluzione con sorgente vibratoria Ivi-MiniVib svolta nel comune di Piedimonte Etneo (CT) in località Presa.
Il presente lavoro ha avuto come obiettivo lo studio dettagliato della porzione superficiale (0-500 metri di profondità) della faglia Pernicana attraverso l’acquisizione e l’elaborazione di dati sismici a riflessione e rifrazione ad alta risoluzione.
E’ stato acquisito un profilo sismico di 715 metri, in località Presa nel comune di Piedimonte Etneo (CT), mediante l’impiego di una sorgente sismica vibratoria ad alta risoluzione. Questo sito è stato scelto in quanto è attraversato dalla rottura superficiale indotta dalla faglia Pernicana
Hybrid Funnel Technique: A Novel Approach for Implant Site Preparation: A Pilot Study.
(1) Background: Different techniques and tools have been developed for implant site preparation. In this clinical scenario, Hybrid Funnel Technique (HFT), a novel osteotomy procedure, has been proposed. (2) Aim: The aim of this retrospective observational study was to consider the different responses to compression of the histological bony compartments (cancellus and cortical). HFT involves the use of multiple drills for the cortical layer preparation and of an osteotome for the osteocompaction of the cancellous bone. (3) Materials and Methods: Following computer-supported implant planning and guided surgery, 10 osteotomies with HFT were performed and 10 implants with the same length and diameter were placed in seven healthy and no daily smoking patients. Periapical X-ray and intraoral photographs were performed at baseline and after 12 months of follow-up to evaluate marginal bone level (MBL) changes and aesthetic results obtained from implant prosthetic rehabilitation. (4) Results: At 1 year of follow-up, 100% of the implants were successfully integrated, MBL change mean value was 0.17 mm ± 0.21. No differences in terms of MBL were noted between thin and thick biotypes. Pink esthetic score (PES) and white esthetic score (WES), assessed one year after definitive restoration placement, were 7.5 ± 2.3 and 8.5 ± 1.1, respectively. (5) Conclusions: Based on the findings of this preliminary clinical study, HFT has led to stability of peri-implant tissues and could represent a reliable technique for surgical preparation of the implant site
MASW Terra-Mare, applicazione a Taranto per il Progetto Beleolico
Per una caratterizzazione sismica del sottosuolo presso la spiaggia dell’insediamento residenziale di "Lido
Azzurro” (TA), area interessata alla realizzazione di un
parco eolico “near-shore”, l'IAMC ha effettuato uno stendimento sismico del tipo terra-mare con metodologia
MASW per la determinazione del profilo verticale delle onde di taglio e del
valore Vs30, in riferimento tra l’altro alla classificazione dei terreni di fondazione degli
interventi in progetto nelle categorie di suolo, come da paragrafo 3.2.2 delle N.T.C. 2008
“D.M. 14/01/2008”
2-C-Methyl-d-lyxono-1,4-lactone
The title compound, C6H10O5, has been crystallized for the first time, allowing the stereochemistry at C-2 and the ring size of the lactone to be firmly established
(2R,5S)-2-Trichloromethyl-3-oxa-1-azabicyclo[3.3.0]octane-4,8-dione
The crystal structure of the title bicyclic oxazolidindione, C7H6Cl3NO3, confirmed the absolute stereochemistry as 2R,5S
3,4-O-Isopropylidene-2-C-methyl-d-arabinono-1,5-lactone
The crystal structure of δ-lactone, C9H14O 5, formed in high diastereoselectivity by the Kiliani reaction of a protected 1-deoxyketose was described. It was observed that the δ-lactone compound adopts a boat conformation in which an OH group occupies a flagpole position. The hydroxy group at atom C1 was clearly found to be in a very hindered position, being additionally attached to a tertiary C atom. As usually expected for sugar derivatives, hydrogen bonding was found to occur between molecules
Decreased Rhes mRNA levels in the brain of patients with Parkinson's disease and MPTP-treated macaques
In rodent and human brains, the small GTP-binding protein Rhes is highly expressed in virtually all dopaminoceptive striatal GABAergic medium spiny neurons, as well as in large aspiny cholinergic interneurons, where it is thought to modulate dopamine-dependent signaling. Consistent with this knowledge, and considering that dopaminergic neurotransmission is altered in neurological and psychiatric disorders, here we sought to investigate whether Rhes mRNA expression is altered in brain regions of patients with Parkinsonâ\u80\u99s disease (PD), Schizophrenia (SCZ), and Bipolar Disorder (BD), when compared to healthy controls (about 200 post-mortem samples). Moreover, we performed the same analysis in the putamen of non-human primate Macaca Mulatta, lesioned with the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Overall, our data indicated comparable Rhes mRNA levels in the brain of patients with SCZ and BD, and their respective healthy controls. In sharp contrast, the putamen of patients suffering from PD showed a significant 35% reduction of this transcript, compared to healthy subjects. Interestingly, in line with observations obtained in humans, we found 27% decrease in Rhes mRNA levels in the putamen of MPTP-treated primates. Based on the established inhibitory influence of Rhes on dopamine-related responses, we hypothesize that its striatal downregulation in PD patients and animal models of PD might represent an adaptive event of the dopaminergic system to functionally counteract the reduced nigrostriatal innervation
α-d-Tagatopyranose
The title compound, C6H12O6, also known as d-Tagatose, occurs in its furanose and pyranose forms in solution, but only the α-pyranose form crystallizes out. In the crystal, the molecules form hydrogen bonded chains propagating in [100] linked by O—H⋯O interactions. Further O—H⋯O bonds cross-link the chains
2‐C‐Azidomethyl‐2‐deoxy‐3,4‐O‐isopropylidene‐d‐ribono‐1,5‐lactone
X-ray crystallographic analysis firmly establishes the ribo stereochemistry and the unusual boat conformation of the title branched carbon chain lactone, C9H13N3O4, arising from an unexpected rearrangement in the nucleophilic substitution of a trifluoromethanesulfonate. There are two molecules in the asymmetric unit. © 2006 International Union of Crystallography Printed in Great Britain - all rights reserved
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