Widespread active seepage activity on the Nile Deep Sea Fan (offshore Egypt) revealed by high-definition geophysical imagery

Fluid escape structures on the Nile Deep Sea Fan were investigated during the MEDIFLUX MIMES expedition in 2004. Mud volcanoes, pockmarks and authigenic carbonate structures were surveyed for the first time with a high-resolution deep-towed 75 kHz sidescan sonar and a 2–8 kHz Chirp sediment echosounder. In combination with existing multibeam bathymetry and detailed seafloor in situ geological observations, these new data allowed detailed seep analyses. About 60 gas flares were detected acoustically in the water column from the sidescan sonar raw data atwater depths from 770 to 1700 m. These gas flares coincide at the seabed with 1) the centres of the mud volcanoes where mud is also extruded, 2) the borders of the mud volcanoes where the emitted gases contribute to the precipitation of authigenic carbonates, and 3) to the edges of broad sheets of authigenic carbonates. Subsurface sediments are commonly disturbed by ascending fluids throughout the delta, with an abundance of seep-related carbonate structures on the seafloor. The feeder channels below mud volcanoes, similar to the gas conduits below the widespread carbonate crust structures and pockmarks, are relatively narrow and, for the vast majority of them, do not exceed a few metres in diameter. The seeps on the Nile Deep Sea Fan clearly follow lineations on the seafloor that ee can relate to faults

Rapport du congrès EUROCALL'99 (Besançon, France)

Avec le soutien de la revue ALSIC, l'association européenne EUROCALL (1999)  (European Association for Computer Assisted Language Learning) a tenu son congrès annuel du mercredi 15 au samedi 18 septembre 1999 pour la première fois en France, à l'université de Franche-Comté à Besançon. Ce congrès fait, chaque année, le point sur les recherches et les applications dans le domaine des environnements informatiques d'aide à l'apprentissage des langues. Les thématiques principales de EUROCALL'99 (1999)  étaient celles des "Systèmes d'Information et de Communication (SIC) dans des situations variées d'apprentissage des langues" et de "l'Évaluation des compétences langagières et language testing". Nous présentons ici les rapports de trois délégués du congrès. Chaque rédacteur adopte un point de vue propre allant du compte rendu précis de la manifestation à une réaction plus personnelle. Le lecteur y trouvera un éclairage sur différents aspects du congrès et aussi sur les attentes variées que peuvent en avoir les délégués suivant leurs spécialités propres

Multi-disciplinary investigation of fluid seepage on an unstable margin: The case of the Central Nile deep sea fan

We report on a multidisciplinary study of cold seeps explored in the Central Nile deep-sea fan of the Egyptian margin. Our approach combines in situ seafloor observation, geophysics, sedimentological data, measurement of bottom-water methane anomalies, pore-water and sediment geochemistry, and 230Th/U dating of authigenic carbonates. Two areas were investigated, which correspond to different sedimentary provinces. The lower slope, at ∼ 2100 m water depth, indicates deformation of sediments by gravitational processes, exhibiting slope-parallel elongated ridges and seafloor depressions. In contrast, the middle slope, at ∼ 1650 m water depth, exhibits a series of debris-flow deposits not remobilized by post-depositional gravity processes. Significant differences exist between fluid-escape structures from the two studied areas. At the lower slope, methane anomalies were detected in bottom-waters above the depressions, whereas the adjacent ridges show a frequent coverage of fractured carbonate pavements associated with chemosynthetic vent communities. Carbonate U/Th age dates (∼ 8 kyr BP), pore-water sulphate and solid phase sediment data suggest that seepage activity at those carbonate ridges has decreased over the recent past. In contrast, large (∼ 1 km2) carbonate-paved areas were discovered in the middle slope, with U/Th isotope evidence for ongoing carbonate precipitation during the Late Holocene (since ∼ 5 kyr BP at least). Our results suggest that fluid venting is closely related to sediment deformation in the Central Nile margin. It is proposed that slope instability leads to focused fluid flow in the lower slope and exposure of ‘fossil’ carbonate ridges, whereas pervasive diffuse flow prevails at the unfailed middle slope

White Matter Atrophy and Cognitive Dysfunctions in Neuromyelitis Optica

Neuromyelitis optica (NMO) is an inflammatory disease of central nervous system characterized by optic neuritis and longitudinally extensive acute transverse myelitis. NMO patients have cognitive dysfunctions but other clinical symptoms of brain origin are rare. In the present study, we aimed to investigate cognitive functions and brain volume in NMO. The study population consisted of 28 patients with NMO and 28 healthy control subjects matched for age, sex and educational level. We applied a French translation of the Brief Repeatable Battery (BRB-N) to the NMO patients. Using SIENAx for global brain volume (Grey Matter, GM; White Matter, WM; and whole brain) and VBM for focal brain volume (GM and WM), NMO patients and controls were compared. Voxel-level correlations between diminished brain concentration and cognitive performance for each tests were performed. Focal and global brain volume of NMO patients with and without cognitive impairment were also compared. Fifteen NMO patients (54%) had cognitive impairment with memory, executive function, attention and speed of information processing deficits. Global and focal brain atrophy of WM but not Grey Matter (GM) was found in the NMO patients group. The focal WM atrophy included the optic chiasm, pons, cerebellum, the corpus callosum and parts of the frontal, temporal and parietal lobes, including superior longitudinal fascicle. Visual memory, verbal memory, speed of information processing, short-term memory and executive functions were correlated to focal WM volumes. The comparison of patients with, to patients without cognitive impairment showed a clear decrease of global and focal WM, including brainstem, corticospinal tracts, corpus callosum but also superior and inferior longitudinal fascicles. Cognitive impairment in NMO patients is correlated to the decreased of global and focal WM volume of the brain. Further studies are needed to better understand the precise origin of cognitive impairment in NMO patients, particularly in the WM

No lack of regulatory B cells in patients with Multiple Sclerosis

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