The Initial Conditions of Clustered Star Formation. II. N2H+ Observations of the Ophiuchus B Core

We present a Nobeyama 45 m Radio Telescope map and Australia Telescope Compact Array pointed observations of N2H+ 1-0 emission towards the clustered, low mass star forming Oph B Core within the Ophiuchus molecular cloud. We compare these data with previously published results of high resolution NH3 (1,1) and (2,2) observations in Oph B. We use 3D Clumpfind to identify emission features in the single-dish N2H+ map, and find that the N2H+ `clumps' match well similar features previously identified in NH3 (1,1) emission, but are frequently offset to clumps identified at similar resolution in 850 micron continuum emission. Wide line widths in the Oph B2 sub-Core indicate non-thermal motions dominate the Core kinematics, and remain transonic at densities n ~ 3 x 10^5 cm^-3 with large scatter and no trend with N(H2). Non-thermal motions in Oph B1 and B3 are subsonic with little variation, but also show no trend with H2 column density. Over all Oph B, non-thermal N2H+ line widths are substantially narrower than those traced by NH3, making it unlikely NH3 and N2H+ trace the same material, but the v_LSR of both species agree well. We find evidence for accretion in Oph B1 from the surrounding ambient gas. The NH3/N2H+ abundance ratio is larger towards starless Oph B1 than towards protostellar Oph B2, similar to recent observational results in other star-forming regions. Small-scale structure is found in the ATCA N2H+ 1-0 emission, where emission peaks are again offset from continuum emission. In particular, the ~1 M_Sun B2-MM8 clump is associated with a N2H+ emission minimum and surrounded by a broken ring-like N2H+ emission structure, suggestive of N2H+ depletion. We find a strong general trend of decreasing N2H+ abundance with increasing N(H2) in Oph B which matches that found for NH3.Comment: 55 pages (manuscript), 15 figures, ApJ accepte

Evaluation of early and late presentation of patients with ocular mucous membrane pemphigoid to two major tertiary referral hospitals in the United Kingdom

PURPOSE: Ocular mucous membrane pemphigoid (OcMMP) is a sight-threatening autoimmune disease in which referral to specialists units for further management is a common practise. This study aims to describe referral patterns, disease phenotype and management strategies in patients who present with either early or established disease to two large tertiary care hospitals in the United Kingdom.\ud \ud PATIENTS AND METHODS: In all, 54 consecutive patients with a documented history of OcMMP were followed for 24 months. Two groups were defined: (i) early-onset disease (EOD:<3 years, n=26, 51 eyes) and (ii) established disease (EstD:>5 years, n=24, 48 eyes). Data were captured at first clinic visit, and at 12 and 24 months follow-up. Information regarding duration, activity and stage of disease, visual acuity (VA), therapeutic strategies and clinical outcome were analysed.\ud \ud RESULTS: Patients with EOD were younger and had more severe conjunctival inflammation (76% of inflamed eyes) than the EstD group, who had poorer VA (26.7%=VA<3/60, P<0.01) and more advanced disease. Although 40% of patients were on existing immunosuppression, 48% required initiation or switch to more potent immunotherapy. In all, 28% (14) were referred back to the originating hospitals for continued care. Although inflammation had resolved in 78% (60/77) at 12 months, persistence of inflammation and progression did not differ between the two phenotypes. Importantly, 42% demonstrated disease progression in the absence of clinically detectable inflammation.\ud \ud CONCLUSIONS: These data highlight that irrespective of OcMMP phenotype, initiation or escalation of potent immunosuppression is required at tertiary hospitals. Moreover, the conjunctival scarring progresses even when the eye remains clinically quiescent. Early referral to tertiary centres is recommended to optimise immunosuppression and limit long-term ocular damage.\ud \u

Narratives to enhance smoking cessation interventions among African-American smokers, the ACCE project

BACKGROUND: Low-income, African-American smokers are less likely to have resources to aid in quitting smoking. Narrative communication may provide an enhancement to traditional smoking cessation interventions like NRT, medications, or behavioral treatments for this audience. After extensive pilot testing of stories and personal experiences with smoking cessation from African-Americans from a low-income community, we conducted a randomized control trial using stories to augment routine inpatient treatment among African-Americans at an urban Southern hospital (N = 300). RESULTS: Differences in smoking cessation outcomes between the intervention (stories DVD + routine clinical treatment) and control (routine clinical treatment) arms were compared using self-report and carbon monoxide measurement at 6-months. Compared to control, individuals who viewed the intervention stories DVD reported greater intentions to quit. Although continuous quitting marginally favored the intervention, our main result did not reach statistical significance (p = 0.16). CONCLUSION: Narrative communication via storytelling to promote smoking cessation among African-Americans in the South is one method to communicate smoking cessation. Results suggest this may not be sufficient as a stand-alone augmentation of routine clinical treatment for continuous smoking cessation. Smoking cessation efforts need to continually assess different means of communicating to smokers about quitting. CLINICAL TRIALS REGISTRATION: The ClinicalTrials.gov Identifier is NCT00101491. This trial was registered January 10, 2005

Elemental Abundances in the Possible Type Ia Supernova Remnant G344.7-0.1

Recent studies on the Galactic supernova remnant (SNR) G344.7-0.1 have commonly claimed its origin to be a core-collapse supernova (SN) explosion, based on its highly asymmetric morphology and/or proximity to a star forming region. In this paper, however, we present an X-ray spectroscopic study of this SNR using Suzaku, which is supportive of a Type Ia origin. Strong K-shell emission from lowly ionized Fe has clearly been detected, and its origin is determined, for the first time, to be the Fe-rich SN ejecta. The abundance pattern is highly consistent with that expected for a somewhat-evolved Type Ia SNR. It is suggested, therefore, that the X-ray point-like source CXOU J170357.8-414302 located at the SNR's geometrical center is not associated with the SNR but is likely to be a foreground object. Our result further indicates that G344.7-0.1 is the first possible Type Ia SNR categorized as a member of the so-called "mixed-morphology" class. In addition, we have detected emission from He-like Al at ~1.6 keV, the first clear detection of this element in the spectrum of an extended X-ray source. The possible enhancement of the Al/Mg abundance ratio from the solar value suggests that the ambient interstellar medium has a relatively high metallicity (not less than 10% of the solar value), if this SNR has indeed a Type Ia origin. We also report marginal detection of Cr and Mn, although the measured fluxes have large statistical and systematic uncertainties.Comment: ApJ in pres

Obstacles to reduction in infantile developmental dysplasia of the hip

Purpose: Identification of anatomical structures that block ­reduction in developmental dysplasia of the hip (DDH) is ­important for the management of this challenging condition. Obstacles to reduction seen on arthrogram are well-known. However, despite the increasing use of MRI in the assessment of adequacy of reduction in DDH, the interpretation of MRI patho-anatomy is ill-defined with a lack of relevant literature to guide clinicians. Method: This is a retrospective analysis of the MRI of patients with DDH treated by closed reduction over a five-year period (between 2009 and 2014). Neuromuscular and genetic disorders were excluded. Each MRI was analysed by two orthopaedic surgeons and a paediatric musculoskeletal radiologist to identify the ligamentum teres, pulvinar, transverse acetabular ligament (TAL), capsule, labrum and acetabular roof cartilage hypertrophy. Inter- and intraobserver reliability was calculated. The minimum follow-up was 12 months. Results: A total of 29 patients (38 hips) underwent closed reduction for treatment of DDH. Eight hips showed persistent subluxation on post-operative MRI. Only three of these eight hips showed an abnormality on arthrogram. The pulvinar was frequently interpreted as ‘abnormal’ on MRI. The main obstacles identified on MRI were the ligamentum teres (15.8%), labrum (13.1%) and acetabular roof cartilage hypertrophy (13.2%). The inter-rater reliability was good for TAL, capsule and pulvinar; moderate for ligamentum teres and labrum; and poor for hypertrophied cartilage. Conclusion: The labrum, ligamentum teres and acetabular roof cartilage hypertrophy are the most important structures seen on MRI preventing complete reduction of DDH. Focused interpretation of these structures may assist in the management of DDH.K. Studer, N. Williams, P. Studer, M. Baker, A. Glynn, B. K. Foster, P. J. Cund

Clubbing masculinities: Gender shifts in gay men's dance floor choreographies

This is an Author's Accepted Manuscript of an article published in Journal of Homosexuality, 58(5), 608-625, 2011 [copyright Taylor & Francis], available online at: http://www.tandfonline.com/10.1080/00918369.2011.563660This article adopts an interdisciplinary approach to understanding the intersections of gender, sexuality, and dance. It examines the expressions of sexuality among gay males through culturally popular forms of club dancing. Drawing on political and musical history, I outline an account of how gay men's gendered choreographies changed throughout the 1970s, 80s, and 90s. Through a notion of “technologies of the body,” I situate these developments in relation to cultural levels of homophobia, exploring how masculine expressions are entangled with and regulated by musical structures. My driving hypothesis is that as perceptions of cultural homophobia decrease, popular choreographies of gay men's dance have become more feminine in expression. Exploring this idea in the context of the first decade of the new millennium, I present a case study of TigerHeat, one of the largest weekly gay dance club events in the United States