915 research outputs found
Collimated Jet or Expanding Outflow: Possible Origins of GRBs and X-Ray Flashes
We investigate the dynamics of an injected outflow propagating in a
progenitor in the context of the collapsar model for gamma-ray bursts (GRBs)
through two dimensional axisymmetric relativistic hydrodynamic simulations.
Initially, we locally inject an outflow near the center of a progenitor. We
calculate 25 models, in total, by fixing its total input energy to be 10^{51}
ergs s^{-1} and radius of the injected outflow to be cm while
varying its bulk Lorentz factor, , and its specific
internal energy, . The injected outflow propagates
in the progenitor and drives a large-scale outflow or jet. We find a smooth but
dramatic transition from a collimated jet to an expanding outflow among
calculated models. The maximum Lorentz factor is, on the other hand, sensitive
to both of and ; roughly . Our finding will explain a smooth transition between the
GRBs, X-ray rich GRBs (XRRs) and X-ray Flashes (XRFs) by the same model but
with different values.Comment: Comments 51 pages, 21 figures. accepted for publication in ApJ high
resolution version is available at
http://www.mpa-garching.mpg.de/~mizuta/COLLAPSAR/collapsar.htm
Role of platelets as mediators that link inflammation and thrombosis in atherosclerosis
Platelets, crucial mediators of the acute complications of atherosclerosis that cause life-threatening ischemic events at late stages of the disease, are also key effectors of inflammation throughout plaque development through their interaction with endothelial and immune cells in the injured vessel wall. During the first steps of atherosclerosis, blood inflammatory leukocytes interact with the damaged endothelium in areas rich in platelet aggregates. In late stages of the disease, platelets secrete several inflammatory molecules, even without forming aggregates. These molecules exacerbate the inflammation and induce the transition from chronic to acute disease, featuring increased instability of the atherosclerotic lesion that results in plaque rupture and thrombosis. Moreover, platelets play an important role in vascular wall remodeling induced by chronic inflammation by controlling vascular cell differentiation and proliferation. In this review, we discuss the role of platelets as cell mediators that link inflammation and thrombosis in atherosclerotic disease and their potential in the development of new therapeutic tools to fight cardiovascular disease.Work in the authorâs laboratories is supported by Centro de Estudios en Alimentos Procesados (CEAP), Conicyt-Regional, Gore Maule, R09I2001, Talca, Chile (Proyecto Basal); The Spanish Ministry of Science and Innovation (MICINN) and the European Regional Development Fund (grant SAF2010-16044); Instituto de Salud Carlos III (ISCIII) (Red de Enfermedades Cardiovasculares [RECAVA], grant RD06/0014/0021). O.M.P. holds a Juan de la Cierva contract (MICINN). The CNIC is supported by the MICINN and the Pro-CNIC Foundation.S
Partial Derivation of Transformation Properties of Quarks and Leptons
Under the assumptions that with
simple is a local symmetry group at high energies, that color is
parity-conserving, and the Y-charges are irreducible, we show that anomaly
constraints imply the minimal set of fermions is fifteen in number. Given this
minimal set, we further show that must be and the unbroken
gauge symmetry is {\it either} color {\it or} the product of color with
electric charge.Comment: 9 pages, UMDHEP 94-72 and IFP-487-UN
Prevalence and Predictors of Urinary Tract Infection and Severe Malaria Among Febrile Children Attending Makongoro Health Centre in Mwanza City, North-Western Tanzania.
In malaria endemic areas, fever has been used as an entry point for presumptive treatment of malaria. At present, the decrease in malaria transmission in Africa implies an increase in febrile illnesses related to other causes among underfives. Moreover, it is estimated that more than half of the children presenting with fever to public clinics in Africa do not have a malaria infection. Thus, for a better management of all febrile illnesses among under-fives, it becomes relevant to understand the underlying aetiology of the illness. The present study was conducted to determine the relative prevalence and predictors of P. falciparum malaria, urinary tract infections and bacteremia among under-fives presenting with a febrile illness at the Makongoro Primary Health Centre, North-Western Tanzania. From February to June 2011, a cross-sectional analytical survey was conducted among febrile children less than five years of age. Demographic and clinical data were collected using a standardized pre-tested questionnaire. Blood and urine culture was done, followed by the identification of isolates using in-house biochemical methods. Susceptibility patterns to commonly used antibiotics were investigated using the disc diffusion method. Giemsa stained thin and thick blood smears were examined for any malaria parasites stages. A total of 231 febrile under-fives were enrolled in the study. Of all the children, 20.3% (47/231, 95%CI, 15.10-25.48), 9.5% (22/231, 95%CI, 5.72-13.28) and 7.4% (17/231, 95%CI, 4.00-10.8) had urinary tract infections, P. falciparum malaria and bacteremia respectively. In general, 11.5% (10/87, 95%CI, 8.10-14.90) of the children had two infections and only one child had all three infections. Predictors of urinary tract infections (UTI) were dysuria (OR = 12.51, 95% CI, 4.28-36.57, P < 0.001) and body temperature (40-41 C) (OR = 12.54, 95% CI, 4.28-36.73, P < 0.001). Predictors of P. falciparum severe malaria were pallor (OR = 4.66 95%CI, 1.21-17.8, P = 0.025) and convulsion (OR = 102, 95% CI, 10-996, P = 0.001). Escherichia coli were the common gram negative isolates from urine (72.3%, 95% CI, 66.50-78.10) and blood (40%, 95%CI, and 33.70-46.30). Escherichia coli from urine were 100% resistant to ampicillin, 97% resistant to co-trimoxazole, 85% resistant to augmentin and 32.4% resistant to gentamicin; and they were 100%, 91.2% and 73.5% sensitive to meropenem, ciprofloxacin and ceftriaxone respectively. Urinary tract infection caused by multi drug resistant Escherichia coli was the common cause of febrile illness in our setting. Improvement of malaria diagnosis and its differential diagnosis from other causes of febrile illnesses may provide effective management of febrile illnesses among children in Tanzania
Detecting Physics At The Post-GUT And String Scales By Linear Colliders
The ability of linear colliders to test physics at the post-GUT scale is
investigated. Using current estimates of measurements available at such
accelerators, it is seen that soft breaking masses can be measured with errors
of about (1-20)%. Three classes of models in the post-GUT region are examined:
models with universal soft breaking masses at the string scale, models with
horizontal symmetry, and string models with Calabi-Yau compactifications. In
each case, linear colliders would be able to test directly theoretical
assumptions made at energies beyond the GUT scale to a good accuracy,
distinguish between different models, and measure parameters that are expected
to be predictions of string models.Comment: Latex, 21 pages, no figure
Vanishing corrections on the intermediate scale and implications for unification of forces
In two-step breaking of a class of grand unified theories including SO(10),we
prove a theorem showing that the scale where the Pati-Salam gauge
symmetry with parity breaks down to the standard gauge group,has vanishing
corrections due to all sources emerging from higher scales such as
the one-loop and all higher loop effects,the GUT-threshold,gravitational
smearing,and string threshold effects. Implications of such a scale for the
unification of gauge couplings with small Majorana neutrino masses are
discussed.In string inspired SO(10) we show that ,needed for neutrino masses,with the GUT scale can
be realized provided certain particle states in the predicted spectum are
light.Comment: 21 pages, Late
Linking the environmental pressures of Chinaâs capital development to global final consumption of the past decades and into the future
Chinaâs rapid growth was fueled by investments that grew more than 10-fold since 1995. Little is known about how the capital assets acquired, while being used in productive processes for years or decades, satisfy global final consumption of goods and services, or how the resource use and emissions that occurred during capital formation are attributable to past or future consumption. Here, enabled by a new global model of capital formation and use, we quantify the linkages over the past 2 decades and into the future between six environmental pressures (EPs) associated with Chinaâs capital formation and attributable to Chinese as well as non-Chinese consumption. We show that only 35% of the capital assets acquired by China from 1995 to 2015, representing 32â39% of the associated EPs (e.g., water consumption, greenhouse gas (GHG) emissions, and metal ore extractions), have been depreciated, while the majority rest will serve future production and consumption. The outsourcing of capital services and the associated EPs are considerable, ranging from 14 to 25% of depending on the EP indicators. Without accounting for the capitalâfinal consumption linkages across time and space, one would miscalculate Chinaâs environmental footprints related to the six EPs by big margins, from â61% to +114%.Industrial Ecolog
Realistic Standard Model Fermion Mass Relations in Generalized Minimal Supergravity (GmSUGRA)
Grand Unified Theories (GUTs) usually predict wrong Standard Model (SM)
fermion mass relation m_e/m_{\mu} = m_d/m_s toward low energies. To solve this
problem, we consider the Generalized Minimal Supergravity (GmSUGRA) models,
which are GUTs with gravity mediated supersymmetry breaking and higher
dimensional operators. Introducing non-renormalizable terms in the super- and
K\"ahler potentials, we can obtain the correct SM fermion mass relations in the
SU(5) model with GUT Higgs fields in the {\bf 24} and {\bf 75} representations,
and in the SO(10) model. In the latter case the gauge symmetry is broken down
to SU(3)_C X SU(2)_L X SU(2)_R X U(1)_{B-L}, to flipped SU(5)X U(1)_X, or to
SU(3)_C X SU(2)_L X U(1)_1 X U(1)_2. Especially, for the first time we generate
the realistic SM fermion mass relation in GUTs by considering the
high-dimensional operators in the K\"ahler potential.Comment: JHEP style, 29 pages, no figure,references adde
General Gauge and Anomaly Mediated Supersymmetry Breaking in Grand Unified Theories with Vector-Like Particles
In Grand Unified Theories (GUTs) from orbifold and various string
constructions the generic vector-like particles do not need to form complete
SU(5) or SO(10) representations. To realize them concretely, we present
orbifold SU(5) models, orbifold SO(10) models where the gauge symmetry can be
broken down to flipped SU(5) X U(1)_X or Pati-Salam SU(4)_C X SU(2)_L X SU(2)_R
gauge symmetries, and F-theory SU(5) models. Interestingly, these vector-like
particles can be at the TeV-scale so that the lightest CP-even Higgs boson mass
can be lifted, or play the messenger fields in the Gauge Mediated Supersymmetry
Breaking (GMSB). Considering GMSB, ultraviolet insensitive Anomaly Mediated
Supersymmetry Breaking (AMSB), and the deflected AMSB, we study the general
gaugino mass relations and their indices, which are valid from the GUT scale to
the electroweak scale at one loop, in the SU(5) models, the flipped SU(5) X
U(1)_X models, and the Pati-Salam SU(4)_C X SU(2)_L X SU(2)_R models. In the
deflected AMSB, we also define the new indices for the gaugino mass relations,
and calculate them as well. Using these gaugino mass relations and their
indices, we may probe the messenger fields at intermediate scale in the GMSB
and deflected AMSB, determine the supersymmetry breaking mediation mechanisms,
and distinguish the four-dimensional GUTs, orbifold GUTs, and F-theory GUTs.Comment: RevTex4, 45 pages, 15 tables, version to appear in JHE
R-parity violation in SU(5)
We show that judiciously chosen R-parity violating terms in the minimal
renormalizable supersymmetric SU(5) are able to correct all the
phenomenologically wrong mass relations between down quarks and charged
leptons. The model can accommodate neutrino masses as well. One of the most
striking consequences is a large mixing between the electron and the Higgsino.
We show that this can still be in accord with data in some regions of the
parameter space and possibly falsified in future experiments.Comment: 30 pages, 1 figure. Revised version. To appear in JHE
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