31 research outputs found

    Production pathways for profitability and valuing ecosystem services for willow coppice in intensive agricultural applications

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    Publication history: Accepted - 14 January 2023; Published online - 20 January 2023Increasing agricultural sustainability is a key challenge facing the globe today. Energy crops, planted as riparian buffers are one way to support this, simultaneously mitigating water quality degradation and climate change. However, the economics of implementing such riparian buffer systems is under researched. Hence this work conducted a bottom-up economic analysis of willow coppice riparian buffers on a Northern Irish dairy farm, which is indicative of agricultural intensification across Europe. This work includes an economic assessment of a willow coppice riparian buffer strip, using harvested yield data from an established willow buffer site for the first time. It also considered the impact of harvesting technology on the economic performance of a willow coppice riparian buffer strip for the first time. The analysis considered three willow production pathways: 1) direct chip harvesting, 2) full-stem harvesting, and 3) a scenario with a guaranteed purchasing contract for fresh chip. Economic performance was considered using net present value over a 25-year plantation lifetime. The full-stem scenario provided the highest economic return over its lifetime with an average yearly net present value of £497 ha−1 (in £ sterling). This system was then considered for integration into a typical dairy farm, assuming 5 % land usage and including government grants for establishing riparian zones. The result was a drop in value of £28 ha−1 yr−1 compared to a dairy-only scenario; however, per litre of milk the farm employing willow coppice riparian buffer strips outperformed a typical dairy farm both environmentally and economically. Further analysis considered a novel approach that included payments for ecosystem services in the economic analysis. This analysis found that the implementation of government payments for ecosystem services (nutrient removal) increased the economic return of the willow coppice riparian buffer system by £400 ha−1 yr−1, resulting in minimal impact on the return from dairy land.This Bryden Centre project is supported by the European Union's INTERREG VA Programme, managed by the Special EU Programmes Body (SEUPB). The views and opinions expressed in this paper do not necessarily reflect those of the European Commission or the Special EU Programmes Body (SEUPB). The work was also supported by Queen's University Belfast and the Agri-Food and Biosciences Institute in Northern Ireland. The authors would like to thank David Gilliland of Organic Resources and Alan Hegan of Hegan Biomass for the expert insight readily provided for this research

    Investigation and management of an outbreak of Salmonella Typhimurium DT8 associated with duck eggs, Ireland 2009 to 2011.

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    Salmonella Typhimurium DT8 was a very rare cause of human illness in Ireland between 2000 and 2008, with only four human isolates from three patients being identified. Over a 19-month period between August 2009 and February 2011, 34 confirmed cases and one probable case of Salmonella Typhimurium DT8 were detected, all of which had an MLVA pattern 2-10-NA-12-212 or a closely related pattern. The epidemiological investigations strongly supported a linkbetween illness and exposure to duck eggs. Moreover, S. Typhimurium with an MLVA pattern indistinguishable (or closely related) to the isolates from human cases, was identified in 22 commercial and backyard duck flocks, twelve of which were linked with known human cases. A range of control measures were taken at farm level, and advice was provided to consumers on the hygienic handling and cooking of duck eggs. Although no definitive link was established with a concurrent duck egg-related outbreak of S. Typhimurium DT8 in the United Kingdom, it seems likely that the two events were related. It may be appropriate for other countries with a tradition of consuming duck eggs to consider the need for measures to reduce the risk of similar outbreaks

    Genome mining and characterisation of a novel transaminase with remote stereoselectivity

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    Microbial enzymes from pristine niches can potentially deliver disruptive opportunities in synthetic routes to Active Pharmaceutical Ingredients and intermediates in the Pharmaceutical Industry. Advances in green chemistry technologies and the importance of stereochemical control, further underscores the application of enzyme-based solutions in chemical synthesis. The rich tapestry of microbial diversity in the oceanic ecosystem encodes a capacity for novel biotransformations arising from the chemical complexity of this largely unexplored bioactive reservoir. Here we report a novel omega-transaminase discovered in a marine sponge Pseudovibrio sp. isolate. Remote stereoselection using a transaminase has been demonstrated for the first time using this novel protein. Application to the resolution of an intermediate in the synthesis of sertraline highlights the synthetic potential of this novel biocatalyst discovered through genomic mining. Integrated chemico-genomics revealed a unique substrate profile, while molecular modelling provided structural insights into this 'first in class' selectivity at a remote chiral centre

    Types of Corruption in Small and Micro Enterprises (SMEs) in Ibadan, Nigeria

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    Corruption is a phenomenon that manifests in various types and forms especially among operators of Small and Micro Enterprises (SMEs). Many actions of the operators which constitute corrupt practices often tend to be overlooked in spite of their grave consequences for the success SMEs in Nigeria. The fight against corruption in Nigeria is more concentrated in the formal sector. This study was, therefore, designed to investigate various forms in which corrupt practices are carried out among Small and Micro Enterprises in Ibadan, Nigeria. Business owners, their employees, apprentices and consumers constituted the study population. Primary data were collected using questionnaire administered on 200 business owners, 150 employees and 150 apprentices randomly chosen in five business districts in Ibadan; and the conduct of 10 in-depth interviews with purposively selected participants. Quantitative data were analysed at uni-variate level using simple percentages and frequencies while qualitative data were content analysed. Findings from the study revealed that corrupt practices were rampant among actors in SMEs and the common types of corrupt practices included stealing (60%), deception of customers (78.4%), tax evasion (62%), sale of fake products (76%), sale of expired products (65.2%), tampering with measurement scales (69.6%), bribery (82.4%), and poor service delivery (73%). The study concludes that the level of corruption in SMEs calls for concern and government should extend the fight against corruption to the informal sector in Nigeria

    Will climate mitigation ambitions lead to carbon neutrality? An analysis of the local-level plans of 327 cities in the EU

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    Cities across the globe recognise their role in climate mitigation and are acting to reduce carbon emissions. Knowing whether cities set ambitious climate and energy targets is critical for determining their contribution towards the global 1.5 °C target, partly because it helps to identify areas where further action is necessary. This paper presents a comparative analysis of the mitigation targets of 327 European cities, as declared in their local climate plans. The sample encompasses over 25% of the EU population and includes cities of all sizes across all Member States, plus the UK. The study analyses whether the type of plan, city size, membership of climate networks, and its regional location are associated with different levels of mitigation ambition. Results reveal that 78% of the cities have a GHG emissions reduction target. However, with an average target of 47%, European cities are not on track to reach the Paris Agreement: they need to roughly double their ambitions and efforts. Some cities are ambitious, e.g. 25% of our sample (81) aim to reach carbon neutrality, with the earliest target date being 2020.90% of these cities are members of the Climate Alliance and 75% of the Covenant of Mayors. City size is the strongest predictor for carbon neutrality, whilst climate network(s) membership, combining adaptation and mitigation into a single strategy, and local motivation also play a role. The methods, data, results and analysis of this study can serve as a reference and baseline for tracking climate mitigation ambitions across European and global cities

    Battery warm-up methodologies at subzero temperatures for automotive applications: Recent advances and perspectives

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    Electric vehicles play a crucial role in reducing fuel consumption and pollutant emissions for more sustainable transportation. Lithium-ion batteries, as the most expensive but least understood component in electric vehicles, directly affect vehicular driving range, safety, comfort, and reliability. However, the overall performance of traction batteries deteriorates significantly at low temperatures due to the reduced electrochemical reaction rate and accelerated health degradation, such as lithium plating. Without timely and effective actions, this performance degradation causes operational difficulties and safety hazards for electric vehicles. Battery warm-up/preheating is of particular importance when operating electric vehicles in cold geographical regions. To this end, this paper reviews various battery preheating strategies, including external convective and conductive preheating, as well as the latest progress in internal heating solutions. The effects of low temperature on batteries from the perspectives of cell performance as well as materials properties are briefly summarized. Thermal science issues involved in warm-up are also elucidated. The framework of battery management systems (BTMS) at low temperatures, including the key design considerations at different battery integration levels and the overall classification of warm-up approaches into external and internal groups, are introduced in detail. Next, a comprehensive literature review on different warm-up strategies is presented, and the basic principles, advantages, disadvantages, and potential improvements of each strategy are elaborated. Finally, future trends of battery warm-up methods are discussed in terms of key technologies, promising opportunities, and challenges

    Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib

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    Abstract Oesophageal cancer is the 6th most common cause of cancer related death worldwide. The current standard of care for oesophageal adenocarcinoma (OAC) focuses on neoadjuvant therapy with chemoradiation or chemotherapy, however the 5-year survival rates remain at < 20%. To improve treatment outcomes it is critical to further investigate OAC tumour biology, metabolic phenotype and their metabolic adaptation to different oxygen tensions. In this study, by using human ex-vivo explants we demonstrated using real-time metabolic profiling that OAC tumour biopsies have a significantly higher oxygen consumption rate (OCR), a measure of oxidative phosphorylation compared to extracellular acidification rate (ECAR), a measure of glycolysis (p = 0.0004). Previously, we identified a small molecule compound, pyrazinib which enhanced radiosensitivity in OAC. Pyrazinib significantly inhibited OCR in OAC treatment-naïve biopsies (p = 0.0139). Furthermore, OAC biopsies can significantly adapt their metabolic rate in real-time to their environment. Under hypoxic conditions pyrazinib produced a significant reduction in both OCR (p = 0.0313) and ECAR in OAC treatment-naïve biopsies. The inflammatory secretome profile from OAC treatment-naïve biopsies is heterogeneous. OCR was positively correlated with three secreted factors in the tumour conditioned media: vascular endothelial factor A (VEGF-A), IL-1RA and thymic stromal lymphopoietin (TSLP). Pyrazinib significantly inhibited IL-1β secretion (p = 0.0377) and increased IL-3 (p = 0.0020) and IL-17B (p = 0.0181). Importantly, pyrazinib did not directly alter the expression of dendritic cell maturation markers or reduce T-cell viability or activation markers. We present a new method for profiling the metabolic rate of tumour biopsies in real-time and demonstrate the novel anti-metabolic and anti-inflammatory action of pyrazinib ex-vivo in OAC tumours, supporting previous findings in-vitro whereby pyrazinib significantly enhanced radiosensitivity in OAC
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