70 research outputs found

    History and activities of the European-Mediterranean Seismological Centre

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    The European-Mediterranean Seismological Centre (EMSC) provides rapid information on earthquakes and their effects, but does not operate seismic stations. It collects and merges parametric earthquake data from seismological agencies and networks around the world and collects earthquake observations from global earthquake eyewitnesses. Since its creation in 1975, it has developed strategies to complement earthquake monitoring activities of national agencies and coordinated its activities in Europe with its sister organisations ORFEUS and EFEHR as well as with global actors, while being part of the transformative EPOS initiative. The purpose of this article is to give a brief history of the EMSC and describe its activities, services and coordination mechanisms

    LINC01133 inhibits invasion and promotes proliferation in an endometriosis epithelial cell line

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    Endometriosis is a common gynecological disorder characterized by ectopic growth of endometrium outside the uterus and is associated with chronic pain and infertility. We investigated the role of the long intergenic noncoding RNA 01133 (LINC01133) in endometriosis, an lncRNA that has been implicated in several types of cancer. We found that LINC01133 is upregulated in ectopic endometriotic lesions. As expression appeared higher in the epithelial endometrial layer, we performed a siRNA knockdown of LINC01133 in an endometriosis epithelial cell line. Phenotypic assays indicated that LINC01133 may promote proliferation and suppress cellular migration, and affect the cytoskeleton and morphology of the cells. Gene ontology analysis of differentially expressed genes indicated that cell proliferation and migration pathways were affected in line with the observed phenotype. We validated upregulation of p21 and downregulation of Cyclin A at the protein level, which together with the quantification of the DNA content using fluorescence-activated cell sorting (FACS) analysis indicated that the observed effects on cellular proliferation may be due to changes in cell cycle. Further, we found testis-specific protein kinase 1 (TESK1) kinase upregulation corresponding with phosphorylation and inactivation of actin severing protein Cofilin, which could explain changes in the cytoskeleton and cellular migration. These results indicate that endometriosis is associated with LINC01133 upregulation, which may affect pathogenesis via the cellular proliferation and migration pathways

    Earthquakes in Switzerland and surrounding regions during 2010

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    This report of the Swiss Seismological Service summarizes the seismic activity in Switzerland and surrounding regions during 2010. During this period, 407 earthquakes and 85 quarry blasts were detected and located in the region under consideration. With a total of only 19 events with ML≥2.5, the seismic activity in the year 2010 was below the average over the previous 35years. The two most noteworthy earthquakes were the ML3.4 Barrhorn event near Sankt Niklaus (VS) and the ML 3.0 event of Feldkirch, both of which produced shaking of intensity I

    Earthquakes in Switzerland and surrounding regions during 2011

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    This report of the Swiss Seismological Service summarizes the seismic activity in Switzerland and surrounding regions during 2011. During this period, 522 earthquakes and 92 quarry blasts were detected and located in the region under consideration. With a total of only 10 events with M L≥2.5, the seismic activity in the year 2011 was far below the average over the previous 36years. Most noteworthy were the earthquake sequence of Sierre (VS) in January, with two events of M L 3.3 and 3.2, the M L 3.3 earthquake at a depth of 31km below Bregenz, and the M L 3.1 event near Delémont. The two strongest events near Sierre produced shaking of intensity I

    Earthquakes in Switzerland and surrounding regions during 2011

    Get PDF
    This report of the Swiss Seismological Service summarizes the seismic activity in Switzerland and surrounding regions during 2011. During this period, 522 earthquakes and 92 quarry blasts were detected and located in the region under consideration. With a total of only 10 events with M L≥2.5, the seismic activity in the year 2011 was far below the average over the previous 36years. Most noteworthy were the earthquake sequence of Sierre (VS) in January, with two events of M L 3.3 and 3.2, the M L 3.3 earthquake at a depth of 31km below Bregenz, and the M L 3.1 event near Delémont. The two strongest events near Sierre produced shaking of intensity I

    Earthquakes in Switzerland and surrounding regions during 2005

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    Abstract.: This report of the Swiss Seismological Service summarizes the seismic activity in Switzerland and surrounding regions during 2005. During this period, 611 earthquakes, 96 quarry blasts and two landslides were detected and located in the region under consideration. With 19 events with ML ≥ 2.5, the seismic activity in the year 2005 was below the average over the last 30 years. However, with the earthquake of Vallorcine (ML 4.9) located just across the border to France, between Martigny and Chamonix, and the two earthquakes of Rumisberg and Brugg (ML 4.1), located in the lower crust beneath the Jura Mountains of northern Switzerland, the year 2005 saw three events that produced shaking of intensity IV and V (EMS98). Of the 611 recorded earthquakes more than 110 events are aftershocks of the Vallorcine quake. Moreover, 51 events occurred within two days at the end of August during a period of very intense rainfalls. The epicenters of these events were concentrated in several clusters distributed over a wide area of central Switzerland, and their focal depths were shallow, so that they most likely constitute a case of precipitationinduced seismicit

    Addressing the challenges of making data, products, and services accessible: an EPOS perspective

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    Novel measurement technologies, additional sensors and increasing data processing capacities offer new opportunities to answer some of the currently most pressing societal and environmental questions. They also contribute to the fact that the available data volume will continue to increase. At the same time, the requirements for those providing such data rise and the needs of users to access it. The EPOS Delivery Framework aims to support this endeavour in the solid Earth domain by providing access to data, products, and services supporting multidisciplinary analyses for a wide range of users. Based on this example, we look at the most pressing issues from when data, products, and services are made accessible, to access principles, ethical issues related to its collection and use as well as with respect to their promotion. Among many peculiarities, we shed light on a common component that affects all fields equally: change. Not only will the amount and type of data, products, and services change, but so will the societal expectations and providers capabilities

    Which Picker Fits My Data? A Quantitative Evaluation of Deep Learning Based Seismic Pickers

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    Seismic event detection and phase picking are the base of many seismological workflows. In recent years, several publications demonstrated that deep learning approaches significantly outperform classical approaches, achieving human-like performance under certain circumstances. However, as studies differ in the datasets and evaluation tasks, it is unclear how the different approaches compare to each other. Furthermore, there are no systematic studies about model performance in cross-domain scenarios, that is, when applied to data with different characteristics. Here, we address these questions by conducting a large-scale benchmark. We compare six previously published deep learning models on eight data sets covering local to teleseismic distances and on three tasks: event detection, phase identification and onset time picking. Furthermore, we compare the results to a classical Baer-Kradolfer picker. Overall, we observe the best performance for EQTransformer, GPD and PhaseNet, with a small advantage for EQTransformer on teleseismic data. Furthermore, we conduct a cross-domain study, analyzing model performance on data sets they were not trained on. We show that trained models can be transferred between regions with only mild performance degradation, but models trained on regional data do not transfer well to teleseismic data. As deep learning for detection and picking is a rapidly evolving field, we ensured extensibility of our benchmark by building our code on standardized frameworks and making it openly accessible. This allows model developers to easily evaluate new models or performance on new data sets. Furthermore, we make all trained models available through the SeisBench framework, giving end-users an easy way to apply these models

    Coordinated and Interoperable Seismological Data and Product Services in Europe: the EPOS Thematic Core Service for Seismology

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    In this article we describe EPOS Seismology, the Thematic Core Service consortium for the seismology domain within the European Plate Observing System infrastructure. EPOS Seismology was developed alongside the build-up of EPOS during the last decade, in close collaboration between the existing pan-European seismological initiatives ORFEUS (Observatories and Research Facilities for European Seismology), EMSC (Euro-Mediterranean Seismological Center) and EFEHR (European Facilities for Earthquake Hazard and Risk) and their respective communities. It provides on one hand a governance framework that allows a well-coordinated interaction of the seismological community services with EPOS and its bodies, and on the other hand it strengthens the coordination among the already existing seismological initiatives with regard to data, products and service provisioning and further development. Within the EPOS Delivery Framework, ORFEUS, EMSC and EFEHR provide a wide range of services that allow open access to a vast amount of seismological data and products, following and implementing the FAIR principles and supporting open science. Services include access to raw seismic waveforms of thousands of stations together with relevant station and data quality information, parametric earthquake information of recent and historical earthquakes together with advanced event-specific products like moment tensors or source models and further ancillary services, and comprehensive seismic hazard and risk information, covering latest European scale models and their underlying data. The services continue to be available on the well-established domain-specific platforms and websites, and are also consecutively integrated with the interoperable central EPOS data infrastructure. EPOS Seismology and its participating organizations provide a consistent framework for the future development of these services and their operation as EPOS services, closely coordinated also with other international seismological initiatives, and is well set to represent the European seismological research infrastructures and their stakeholders within EPOS.info:eu-repo/semantics/publishedVersio
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