Reflexionemos como comunidad profesional docente sobre la naturaleza del aprendizaje en temas de biología de la educación básica

In this workshop, participants, as a community of teaching professionals, will analyze on the nature of school learning. The analysis arises from the perception evoked by the participants around the actions carried out by three teachers of the preschool, primary and secondary educational levels, who perform some teaching sequence in biology subjects. The classes that are to be watch are videotaped and based on them, a record of the class dynamics will be made. Finally, based upon some frameworks the community will reach a consensus and some criteria points will be proposed for new observations and collaboration for new analyzes. The above with the purpose of providing elements of discussion and analysis around of what our teachers expect their basic education students to learn in science classes when biology issues are addressed.En este taller los participantes, como una comunidad de profesionales docentes, reflexionaran sobre la naturaleza del aprendizaje escolar. La reflexión surge de la percepción evocada por los participantes alrededor de las acciones realizadas por tres docentes de los niveles educativos preescolar, primaria y secundaria, quienes realizan alguna secuencia de enseñanza en temas de biología. Las clases a observar están videograbadas y con base en ellas, se realizarán registros de la dinámica de la clase. Finalmente, a partir de algunos referentes se concretarán las reflexiones en comunidad y se propondrán algunos puntos de partida para nuevas observaciones y colaboración para nuevos análisis. Lo anterior con el propósito de aportar elementos de discusión y análisis en torno al que esperamos los profesores que aprendan nuestros alumnos de educación básica en las clases de ciencias cuando se abordan temas de biología

La naturaleza del aprendizaje en la práctica docente desde una comunidad de desarrollo profesional docente: un caso de análisis en torno a una clase para la clasificación de los seres vivos

There are a significant number of investigations, nationally and internationally, that address the phenomenon of Teaching Practice and teacher training. However, most of these address the reflection, analysis and discussion on teaching practice (TP), from generalist perspectives, that is, from pedagogy in general and not from specific fields or knowledge. Therefore, it is relevant to inquire about the TP, from the teacher himself, as an active subject and not as an object of knowledge; therefore, it is preponderant to recognize the knowledge of the teacher, allowing joint spaces for reflection with other teachers about their work such as a Community of Professional Development of Teachers (CODEP-DO), where they reflect on the nature of learning in the class of sciences Here, the results of the analysis work around the nature of the learning of a CODEP-DO composed of 18 preschool, primary and secondary teachers, who voluntarily participated in a workshop-, when observing the actions carried out by an elementary teacher, presented in the video recording of her class, while working on the topic of classification of living beings and analyzing them from categories such as: student's role, object of learning, achievements and evaluation of learning. Finding that while CODEP-DO identifies with a constructivist vision of science learning, since it recognizes the importance of community work and student interaction, concepts such as 'classification criteria' remain the center of the teaching work.Tanto en el ámbito nacional como en el internacional se encuentra un número importante de investigaciones que abordan el fenómeno de la Práctica Docente y la formación continua de maestros. Sin embargo, la mayoría de éstas abordan la reflexión, análisis y discusión sobre la Práctica Docente (PD) desde perspectivas generalistas, es decir; desde la pedagogía en general y no desde los campos o saberes específicos. Por ello, resulta relevante indagar sobre la PD, desde el docente mismo, como un sujeto activo y no como un objeto de conocimiento; por ende, es preponderante reconocer el saber del profesor, posibilitándole espacios conjuntos de reflexión con otros docentes sobre su quehacer tal como una Comunidad de Desarrollo Profesional Docente (CODEP-DO), donde se reflexione en torno a la naturaleza del aprendizaje en la clase de ciencias. Aquí, se reportan los resultados del trabajo de análisis realizado por 18 docentes de educación básica -preescolar, primaria y secundaria- que conformaron una CODEP-DO de manera voluntaria, al ser convocados a participar en un curso-taller. Ellos observaron una videograbación de las acciones realizadas por una docente de primaria, cuando trabajaba el tema de clasificación de los seres vivos; analizaron las acciones docentes desde categorías tales como: papel del alumno, objeto de aprendizaje, logros y evaluación del aprendizaje. Encontrándose que si bien la CODEP-DO, se identifica con una visión constructivista del aprendizaje de las ciencias, ya que reconoce la importancia del trabajo en comunidad y la interacción entre el alumnado, los conceptos como ‘criterios de clasificación’ siguen siendo el centro del trabajo docente

Oxidative Stress and Parkinson’s Disease: Effects on Environmental Toxicology

Epidemiological studies have found an increased risk of Parkinson’s disease (PD) with environmental factors such as exposure to substances derived from industrial processes, use of agrochemicals, or living in a rural environment. The hypothesis that certain environmental toxins could be the source of the EP is supported by the discovery that chemicals such as herbicides paraquat, diquat, and the fungicide maneb are selectively toxic in nigrostriatal dopaminergic neurons. Also, one of the insecticides produced by plants, such as rotenone, and by-product of the synthesis of synthetic heroin MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) can be reproduced in animal models where neurochemicals, histopathological, and clinical characteristic of PD can be found. Interestingly, there are similarities in the chemical structure of paraquat and MPTP. Recent evidence exhibited that inflammation and oxidative stress play an essential role in the development of PD. So, in our laboratory we found that in an animal model melatonin decreases the products of lipid oxidation, nitric oxide metabolites, and the activity of cyclooxygenase 2, which are induced by an intraperitoneal injection of MPTP. This suggests that the neuroprotective effects of melatonin are partially attributed to its antioxidant scavenging and anti-inflammatory action

INNOVASONORA: gestión de archivos sonoros, sonido inmersivo y realidad virtual en plataformas LMS

Memoria del proyecto de innovación docente "Innovasonora" (Curso 2021-2022

INNOVASONORA: desarrollo de recursos para la transmisión digital de los archivos sonoros y la aplicación de la realidad virtual como complemento de la enseñanza presencial

Memoria del proyecto de innovación docente nº 208 (curso 2020-2021

Famílies botàniques de plantes medicinals

Facultat de Farmàcia, Universitat de Barcelona. Ensenyament: Grau de Farmàcia, Assignatura: Botànica Farmacèutica, Curs: 2013-2014, Coordinadors: Joan Simon, Cèsar Blanché i Maria Bosch.Els materials que aquí es presenten són els recull de 175 treballs d’una família botànica d’interès medicinal realitzats de manera individual. Els treballs han estat realitzat per la totalitat dels estudiants dels grups M-2 i M-3 de l’assignatura Botànica Farmacèutica durant els mesos d’abril i maig del curs 2013-14. Tots els treballs s’han dut a terme a través de la plataforma de GoogleDocs i han estat tutoritzats pel professor de l’assignatura i revisats i finalment co-avaluats entre els propis estudiants. L’objectiu principal de l’activitat ha estat fomentar l’aprenentatge autònom i col·laboratiu en Botànica farmacèutica

Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism

Background Atrial fibrillation (AF) may exist before or occur early in the course of pulmonary embolism (PE). We determined the PE outcomes based on the presence and timing of AF. Methods and Results Using the data from a multicenter PE registry, we identified 3 groups: (1) those with preexisting AF, (2) patients with new AF within 2 days from acute PE (incident AF), and (3) patients without AF. We assessed the 90-day and 1-year risk of mortality and stroke in patients with AF, compared with those without AF (reference group). Among 16 497 patients with PE, 792 had preexisting AF. These patients had increased odds of 90-day all-cause (odds ratio [OR], 2.81; 95% CI, 2.33-3.38) and PE-related mortality (OR, 2.38; 95% CI, 1.37-4.14) and increased 1-year hazard for ischemic stroke (hazard ratio, 5.48; 95% CI, 3.10-9.69) compared with those without AF. After multivariable adjustment, preexisting AF was associated with significantly increased odds of all-cause mortality (OR, 1.91; 95% CI, 1.57-2.32) but not PE-related mortality (OR, 1.50; 95% CI, 0.85-2.66). Among 16 497 patients with PE, 445 developed new incident AF within 2 days of acute PE. Incident AF was associated with increased odds of 90-day all-cause (OR, 2.28; 95% CI, 1.75-2.97) and PE-related (OR, 3.64; 95% CI, 2.01-6.59) mortality but not stroke. Findings were similar in multivariable analyses. Conclusions In patients with acute symptomatic PE, both preexisting AF and incident AF predict adverse clinical outcomes. The type of adverse outcomes may differ depending on the timing of AF onset.info:eu-repo/semantics/publishedVersio

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Evolving trends in the management of acute appendicitis during COVID-19 waves. The ACIE appy II study

Background: In 2020, ACIE Appy study showed that COVID-19 pandemic heavily affected the management of patients with acute appendicitis (AA) worldwide, with an increased rate of non-operative management (NOM) strategies and a trend toward open surgery due to concern of virus transmission by laparoscopy and controversial recommendations on this issue. The aim of this study was to survey again the same group of surgeons to assess if any difference in management attitudes of AA had occurred in the later stages of the outbreak. Methods: From August 15 to September 30, 2021, an online questionnaire was sent to all 709 participants of the ACIE Appy study. The questionnaire included questions on personal protective equipment (PPE), local policies and screening for SARS-CoV-2 infection, NOM, surgical approach and disease presentations in 2021. The results were compared with the results from the previous study. Results: A total of 476 answers were collected (response rate 67.1%). Screening policies were significatively improved with most patients screened regardless of symptoms (89.5% vs. 37.4%) with PCR and antigenic test as the preferred test (74.1% vs. 26.3%). More patients tested positive before surgery and commercial systems were the preferred ones to filter smoke plumes during laparoscopy. Laparoscopic appendicectomy was the first option in the treatment of AA, with a declined use of NOM. Conclusion: Management of AA has improved in the last waves of pandemic. Increased evidence regarding SARS-COV-2 infection along with a timely healthcare systems response has been translated into tailored attitudes and a better care for patients with AA worldwide