Taking A Stand: The Effects Of Standing Desks On Task Performance And Engagement

Time spent sitting is associated with negative health outcomes, motivating some individuals to adopt standing desk workstations. This study represents the first investigation of the effects of standing desk use on reading comprehension and creativity. In a counterbalanced, within-subjects design, 96 participants completed reading comprehension and creativity tasks while both sitting and standing. Participants self-reported their mood during the tasks and also responded to measures of expended effort and task difficulty. In addition, participants indicated whether they expected that they would perform better on work-relevant tasks while sitting or standing. Despite participants’ beliefs that they would perform worse on most tasks while standing, body position did not affect reading comprehension or creativity performance, nor did it affect perceptions of effort or difficulty. Mood was also unaffected by position, with a few exceptions: Participants exhibited greater task engagement (i.e., interest, enthusiasm, and alertness) and less comfort while standing rather than sitting. In sum, performance and psychological experience as related to task completion were nearly entirely uninfluenced by acute (~30-min) standing desk use. View Full-Tex

P-glycoprotein and its role in drug-drug interactions

Efflux transporters such as P-glycoprotein play an important role in drug transport in many organs. In the gut, P-glycoprotein pumps drugs back into the lumen, decreasing their absorption. Drugs which induce P-glycoprotein, such as rifampicin, can reduce the bioavailability of some other drugs. Inhibitors of P-glycoprotein, such as verapamil, increase the bioavailability of susceptible drugs. Many, but not all, of the drugs which are transported by P-glycoprotein are also metabolised by cytochrome P450 3A4. Important substrates of P-glycoprotein include calcium channel blockers, cyclosporin, dabigatran etexilate, digoxin, erythromycin, loperamide, protease inhibitors and tacrolimus. Predicting clinically important interactions is difficult because of interindividual differences in drug transport

Galactic Rotation Dynamics in f(T) gravity

We investigate galactic rotation curves in $f(T)$ gravity, where $T$ represents a torsional quantity. Our study centers on the particular Lagrangian $f(T)=T+\alpha{T^n}$, where $|n|\neq 1$ and $\alpha$ is a small unknown constant. To do this we treat galactic rotation curves as being composed from two distinct features of galaxies, namely the disk and the bulge. This process is carried out for several values of the index $n$. The resulting curve is then compared with Milky Way profile data to constrain the value of the index $n$ while fitting for the parameter $\alpha$. These values are then further tested on three other galaxies with different morphologies. On the galactic scale we find that $f(T)$ gravity departs from standard Newtonian theory in an important way. For a small range of values of $n$ we find good agreement with data without the need for exotic matter components to be introduced.Comment: 18 pages, 6 figures, Accepted for publication in the EPJ

Temperature, light and nitrate sensing coordinate Arabidopsis seed dormancy cycling resulting in winter and summer annual phenotypes

Seeds use environmental cues to sense the seasons and their surroundings to initiate the plants life cycle. Dormancy cycling underlying this process is extensively described, but the molecular mechanism is largely unknown. To address this we selected a range of representative genes from published array experiments in the laboratory and investigated their expression patterns in seeds of Arabidopsis ecotypes, having contrasting life cycles, over an annual dormancy cycle in the field. We show how mechanisms identified in the laboratory are coordinated in response to the soil environment to determine dormancy cycles that result in winter and summer annual phenotypes. Our results are consistent with a seed specific response to seasonal temperature patterns (temporal sensing) involving the gene DELAY OF GERMINATION1 (DOG1) that indicates the correct season; and concurrent temporally driven co-opted mechanisms that sense spatial signals i.e. nitrate via CBL-INTERACTING PROTEIN KINASE 23 (CIPK23) phosphorylation of the NITRATE TRANSPORTER 1 (NRT1.1) and light via PHYTOCHROME A (PHYA). In both ecotypes studied, when all three genes have low expression there is enhanced GIBBERELLIN 3 BETA-HYDROXYLASE 1 (GA3ox1) expression, exhumed seeds have the potential to germinate in the laboratory, and the initiation of seedling emergence occurs following soil disturbance (exposure to light) in the field. Unlike DOG1, expression of MOTHER of FLOWERING TIME (MFT) has an opposite thermal response in seeds of the two ecotypes indicating a role in determining their different dormancy cycling phenotypes

Linear and nonlinear optical pulse characterisation

Developmental work on the generation and measurement of ultrashort pulses has been performed. A colliding pulse, passively mode-locked (CPM) ring dye laser has been investigated by spectral analysis and the nonlinear technique of second harmonic generation autocorrelation. Two systems for the intracavity compensation of group velocity dispersion (GVD) have been experimentally compared in the CPM laser. Initially one scheme, utilising Gires-Toumois interferometers, has achieved pulse durations of 64 fs. A second technique employing a four-prism sequence within the cavity gave typical pulse durations of -40 fs and focussing adjustments within the jets achieved durations as short as 19 fs for the first time. A realtime interferometric autocorrelator was constructed and detailed theoretical work has been performed to model the resultant fringe resolved autocorrelations as a function of pulseshape and frequency chirp. Spectral and autocorrelation analysis of the CPM laser led to the inference that the laser pulse intensity profiles were distinctly asymmetric. The main sources of frequency chirp within the laser cavity were assessed in order to find possible explanations for this type of laser behaviour. The linear pulse measurement technique employing synchroscan streak cameras was also critically assessed in terms of the available temporal resolutions as a function of phase noise in the RF deflection signal. Two streak tube designs, the Photochron II and the Photochron IV, have been experimentally compared employing the CPM laser as a test pulse source. Optimisation of the synchronisation circuitry has allowed the notable achievement of a temporal resolution of 0.93ps for the Photochron IV streak camera. A computer-interfaced readout system incorporating a charge coupled device (CCD) sensor has been developed which allows the recording of synchroscan streak events with a digitisation accuracy up to 12 bits. Preliminary experimentation was also performed to investigate the feasibility of incorporating a electron sensitive CCD structure within the envelope of the streak camera. It is intended that such a streak camera will be incorporated in a spaceborne laser ranging system and a theoretical assessment of the expected instrument performance has been performed. The above investigations have direct relevance to other types of ultrashort pulse sources and their application in optical communications, time-resolved spectroscopy and ultrafast electrooptic sampling

Learners as Assessors

2007In the recent shift in educational theory from transmission of knowledge to transformation of knowledge and integration of knowledge with existing personal constructs and meanings, assessment has taken on new affective goals, in which the personal growth of the learner is becoming increasingly important. It is no longer defensible to use discrete-item testing of dubious constructs or to sample performance as a means of inferring underlying competence or abilities, if assessment is really concerned with providing information on learning. Instead, the need to understand performance itself and the processing (and affective) factors which influence it, suggest an integration of assessment and instruction, and a student-centered approach to assessment. This paper therefore offers some suggestions on how self-assessment might be incorporated in the Korean EFL classroom

Modified Gravity Research

Five small articles by each author: 1 The Gravity Research Group by Jackson Levi Said 2 Cosmology and Gravity: The dark side of the universe by Gabriel Farrugia 3 Galactic Rotation Dynamics in Modifi ed Gravity by Andrew Finch 4 Exotic Stars by Mark Pacepeer-reviewe

Improved method for the scalar control of induction motor drives

Many control schemes have been proposed for induction motors, which are in themselves highly complex non-linear and sometimes internally unstable systems.One of themost accurate control schemes is encodered rotor flux orientated vector control. The advantages and disadvantages of this control are well known and several variations, or reduced vector schemes, have been proposed. This study introduces an improved encoderless scalar, or approximated vector, control method for induction machines which can be applied to general purpose applications that do not require the most precise control. The proposed method overcomes practical difficulties and is suitable for industrial applications. The slip compensated stator flux linkage oriented scheme proposed in this study does not require flux estimation or a speed sensor, only requiring nameplate data, stator current and stator resistance measurement, which can easily be determined at start-up. Simulation and experimental investigations including field weakening operation and the effect of stator resistance variation demonstrate the improved performance of the new scheme compared to previous open loop V/Hz and stator resistive compensated schemes especially at low rotor speeds