Motion Detector with IR Matrix Sensor using IQRF Technology

Tato bakalářská práce se zabývá implementací algoritmu pro detekci a klasifikaci pohybu. Cílem bylo realizovat samotné vyhodnocování na úrovni mikrokontroléru a kompletní řešení implementovat do internetu věcí pomocí bezdrátové technologie IQRF. Práce se tedy mimo výběr vhodných metod digitálního zpracování obrazu a návrhu samotných algoritmů, zabývá také návrhem a realizací IQRF komunikačního modulu pro již existující hardware, a tedy rozšíření jeho modularity o technologii, již neposkytuje výrobce. V rámci práce vznikl také požadavek pro snadnou a rychlou vizualizaci dat posílaných z maticového infračerveného snímače, jenž byl vyřešen realizovanou počítačovou aplikací. Samotný výsledek práce byl otestován a navrhnuta možná reálná použití včetně ukázky možnosti vizualizace a naprogramované aplikace ve vývojovém prostředí Node-RED.This bachelor thesis deals with the implementation of an algorithm for motion detection and its classification. The aim was to realise the evaluation on microcontroller unit itself and to implement the complete solution into the Internet of Things using IQRF wireless technology. Thus, in addition to selecting suitable methods of digital image processing and design of algorithms themselves, this work also deals with the design and implementation of IQRF communication module for already existing hardware, and thus the extension of its modularity by technology not provided by the manufacturer. This work also created a requirement for easy and fast visualization of data sending from a matrix infrared sensor, which was solved by a developed desktop application. The results of the work itself were tested and possible real use cases were suggested, including example of possible visualization and created application with development tool Node-RED.450 - Katedra kybernetiky a biomedicínského inženýrstvívýborn

Development of Ejpovice from 19. century to the present

Studie se zabývá vývojem sídla Ejpovice od 19. století do současnosti. Oblast zájmu se nachází v Plzeňském kraji, v okrese Rokycany. Má práce je zaměřena na vývoj počtu obyvatel, na hodnocení změn ve struktuře obyvatelstva v průběhu let, na zhodnocení vývoje zástavby v sídle a na zhodnocení občanské vybavenosti sídla. Tento vývoj a změny jsou v práci znázorněny a hodnoceny pomocí tabulek a grafů, které jsou v práci následně popsány.Katedra geografieObhájenoMy study conserns the development of settlement Ejpovice from the 19 th century up to the present. This area of my interest is situated in Pilsen region district Rokycany.My survey focus my attention on the development of number of inhabitans, on evaluation changes in population structure over the years, on evaluation housing development and facilities in Ejpovice. This development and changes are represented by charts and graphs. These charts are subsequently described in my study

External Validation of UDCA Response Score in Slovak and Croatian Patients with Primary Biliary Cholangitis

Background. Ursodeoxycholic acid response score (URS) is a prognostic model that estimates the baseline probability of treatment response after 12 months of ursodeoxycholic acid (UDCA) therapy in patients with primary biliary cholangitis (PBC). Aim. To independently evaluate the predictive performance of the URS model. Methods. We used a cohort of Slovak and Croatian treatment-naïve PBC patients to quantify the discrimination ability using the area under receiver operating characteristic curve (AUROC) and its 95% confidence interval (CI). Furthermore, we evaluated the calibration using calibration belts. The primary outcome was treatment response after 12 months of UDCA therapy defined as values of alkaline phosphatase ≤1.67 × upper limit of normal. Results. One hundred and ninety-four patients were included. Median pretreatment age was 56 years (interquartile range 49–62). Treatment response was achieved in 79.38% of patients. AUROC of the URS was 0.81 (95% CI 0.73–0.88) and the calibration belt revealed that response rates were correctly estimated by predicted probabilities. Conclusion. Our results confirm that the URS can be used in treatment-naïve PBC patients for estimating the treatment response probability after 12 months of UDCA therapy

Prognostic Factors in Primary Biliary Cholangitis: A Retrospective Study of Joint Slovak and Croatian Cohort of 249 Patients

Objective: To identify pretreatment laboratory parameters associated with treatment response and to describe the relationship between treatment response and liver decompensation in patients with primary biliary cholangitis treated with ursodeoxycholic acid. Methods: We defined treatment response as both ALP ≤ 1.67 × ULN and total bilirubin ≤ 2 × ULN. Multiple logistic regression analyses were performed to adjust for confounding effects of sociodemographic variables. Results: Pretreatment total bilirubin ((TB); OR = 0.3388, 95%CI = 0.1671–0.6077), ALT (OR = 0.5306, 95%CI = 0.3830–0.7080), AST (OR = 0.4065, 95%CI = 0.2690–0.5834), ALP (OR = 0.3440, 95%CI = 0.2356–0.4723), total cholesterol ((TC); OR = 0.7730, 95%CI = 0.6242–0.9271), APRI (OR = 0.3375, 95%CI = 0.1833–0.5774), as well as pretreatment albumin (OR = 1.1612, 95%CI = 1.0706–1.2688) and ALT/ALP (OR = 2.4596, 95%CI = 1.2095–5.5472) were associated with treatment response after six months of treatment. Pretreatment TB (OR = 0.2777, 95%CI = 0.1288–0.5228), ALT (OR = 0.5968, 95%CI = 0.4354–0.7963), AST (OR = 0.4161, 95%CI = 0.2736–0.6076), ALP (OR = 0.4676, 95%CI = 0.3487–0.6048), APRI (OR = 0.2838, 95%CI = 0.1433–0.5141), as well as pretreatment albumin (OR = 1.2359, 95%CI = 1.1257–1.3714) and platelet count (OR = 1.0056, 95%CI = 1.0011–1.0103) were associated with treatment response after 12 months of treatment. Treatment response after 6 months of UDCA therapy is significantly associated with treatment response after 12 months of UDCA therapy (OR = 25.2976, 95% CI = 10.5881–68.4917). Treatment responses after 6 and 12 months of UDCA therapy decrease the risk of an episode of liver decompensation in PBC patients (OR = 12.1156, 95%CI = 3.7192–54.4826 and OR = 21.6000, 95%CI = 6.6319–97.3840, respectively). Conclusions: There are several pretreatment laboratory parameters associated with treatment response in patients with primary biliary cholangitis. Treatment response after six months is significantly associated with treatment response after 12 months of ursodeoxycholic acid (UDCA) therapy. Treatment responses after 6 and 12 months of UDCA decrease the risk of an episode of liver decompensation