The case of organizational behavior in Portuguese junior enterprises: Embeddedness, work-life balance, motivation and satisfaction

In nowadays’ context, it is becoming increasingly important for the new entrants in the labor market to differentiate themselves from the others and to be perceived as relevant and valuable human resources. In order to achieve this, students are starting to engage in several different initiatives that improve their résumé, such as Junior Enterprises. This type of enterprises, which were created in 1967, has been developed in several countries, with special incidence in European ones and also in Brazil. In short, they appear as an opportunity for the university’s students to apply their knowledge into real companies, which are their clients. Therefore, in order to deliver a good service, Junior Enterprises must assure a good performance from their members, which, according to several different authors, can be acknowledged through Job Embeddedness, Work-Life Balance, Motivation and Satisfaction. Thus, this research, which was conducted with a sample of Portuguese Junior Entrepreneurs, concluded that Satisfaction impacts positively on Performance, as well as Work-Family Conflict. Other important conclusions of the present research were that Satisfaction acts as a mediator between Job Embeddedness and Performance, and also that Family-Work Conflict does not have a relationship with Performance. Regarding Motivation, it was not possible to study the relationship of this variable with any other, due to the lack of confirmation of required dimensions.No contexto económico e empresarial atual, torna-se importante para os recém-chegados ao mercado de trabalho que sejam capazes de se diferenciar dos demais e, também, que sejam percecionados como recursos humanos relevantes e valiosos. Para que este objetivo seja alcançado, os estudantes começam a envolver-se em diferentes atividades extra-curriculares, como forma de melhorar o seu curriculum vitae, tal como é o caso de Júnior Empresas. Este tipo de Empresas, que foi criado em 1967, tem vindo a surgir em diferentes países, com especial destaque em países Europeus e no Brasil. Desta forma, estas empresas destacam-se como uma oportunidade para os estudantes universitários aplicarem o seu conhecimento em empresas reais, que se assumem como seus clientes. Assim, de forma a oferecerem um bom serviço aos seus clientes, as Júnior Empresas devem assegurar um bom desempenho da parte dos seus membros, o que, de acordo com diversos autores, pode ser alcançado através da sua integração, motivação e satisfação, bem como através de um adequado equilíbrio entre a vida pessoal e profissional dos membros. Este estudo, conduzido numa amostra de Júnior Empresários Portugueses, demonstrou, então, que a Satisfação impacta positivamente no Desempenho, tal como o Conflito Trabalho-Família. Para além disto, outras conclusões importantes foram a de que a Satisfação funciona como um mediador entre a Integração e o Desempenho e, também, a de que o Conflito Família-Trabalho não se relaciona com o Desempenho dos membros. Finalmente, e relativamente à Motivação, não foram possível tirar qualquer conclusão relativamente à relação entre esta variável e qualquer outra, devido à falta de confirmação das dimensões necessárias a esse estudo

Views and Experience of People with Diabetes, Informal Carers, and Healthcare Professionals in Portugal

INTRODUCTION: The increasing burden of diabetes poses a great challenge to healthcare systems and economy worldwide. Although modern therapeutic strategies for diabetes are widely available, most patients still fail to achieve optimal clinical targets and well-being. The primary objective of this study was to assess and explore potential drivers and successful management of diabetes among people with diabetes, family members and healthcare professionals in Portugal, by applying the protocol of the multinational study "Diabetes, Attitudes, Wishes and Needs (DAWN2)". MATERIAL AND METHODS: A total of 767 adults, including 417 people with diabetes, 123 family members and 227 healthcare professionals, participated in the study. Surveys assessed health-related quality of life, self-management, attitudes/beliefs, social support and priorities for improvement areas in diabetes care. RESULTS: Diabetes has a negative impact on the physical health and emotional well-being of patients in Portugal and is also a psychological burden for family members. Earlier diagnosis and treatment of diabetes were mentioned as a major area of improvement. Healthcare professionals indicated the need for diabetes self-management education. CONCLUSION: We have used for the first time in Portugal the DAWN2 protocol to address the wishes, needs, and attitudes of Portuguese diabetes patients, their relatives, and healthcare professionals regarding the disease.publishersversionepub_ahead_of_prin

Agent-based model of diffusion of N-acyl homoserine lactones in a multicellular environment of Pseudomonas aeruginosa and Candida albicans

Experimental incapacity to track microbemicrobe interactions in structures like biofilms, and the complexity inherent to the mathematical modelling of those interactions, raises the need for feasible, alternative modelling approaches. This work proposes an agent-based representation of the diffusion of N-acyl homoserine lactones (AHL) in a multicellular environment formed by Pseudomonas aeruginosa and Candida albicans. Depending on the spatial location, C. albicans cells were variably exposed to AHLs, an observation that might help explain why phenotypic switching of individual cells in biofilms occurred at different time points. The simulation and algebraic results were similar for simpler scenarios, although some statistical differences could be observed (p<0.05). The model was also successfully applied to a more complex scenario representing a small multicellular environment containing C. albicans and P. aeruginosa cells encased in a 3-D matrix. Further development of this model may help create a predictive tool to depict biofilm heterogeneity at the single-cell level.This work has been funded by a Research Grant 2014 by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) to AL; the Portuguese Foundation for Science and Technology (FCT) [grant numbers UID/ BIO/04469/2013, UID/EQU/00511/2013] units and COMPETE 2020 [grant numbers POCI-01-0145-FEDER-006684, POCI-01-0145-FEDER-006939]; North Portugal Regional Operational Programme (NORTE 2020) [grant number NORTE‐01‐0145‐FEDER‐000005 – LEPABE-2-ECO-INNOVATION] under the Portugal 2020 Partnership Agreement, through the European Regional Development Fund (ERDF).info:eu-repo/semantics/publishedVersio

Influenza severe cases in hospitals, between 2014 and 2016 in Portugal

Rede Portuguesa de Laboratórios para o Diagnóstico da GripeBackground: Since 2009, the Portuguese Laboratory Network (PLNID) for Influenza Diagnosis has integrated 15 Laboratories in mainland and Atlantic Islands of Azores and Madeira. This PLNID added an important contribute to the National Influenza Surveillance Program regarding severe and hospitalized influenza cases. The present study aims to describe influenza viruses detected in influenza like illness (ILI) cases: outpatients (Outp), hospitalized (Hosp), and intensive care units (ICU), between 2014 and 2016. Methods: The PLNID performs influenza virus diagnosis by biomolecular methodologies. Weekly reports to the National Influenza Reference Laboratory ILI cases tested for influenza. Reports include data on detecting viruses, hospital assistance, antiviral therapeutics, and information on death outcome. Were reported during two winter seasons 8059 ILI cases,being 3560 cases in 2014/15 (1024 in Outp, 1750 Hosp, and 606 in ICU) and 4499 cases in 2015/2016 (1933 in Outp, 1826 Hosp, and 740 in ICU). Results: The higher percentage of influenza positive cases were detected in Outp in both seasons, 18% during 2014/15 and 20% in 2015/16. In 2014/15,influenza cases were more frequent in individuals older than 65 years old and these required more hospitalizations,even in ICU. In 2015/16,the influenza cases were mainly detected in individuals between 15-64 years old. A higher proportion of influenza positive cases with hospitalization in ICU were observed in adults between 45-64 years old.During the study period,the predominant circulating influenza viruses were different in the two seasons: influenza B and A(H3) co-circulated in 2014/15,and influenza A(H1)pdm09 was predominant during 2015/16. Even when influenza A is notthe dominant virus, A(H3) and A(H1)pdm09 subtypes correlate with higher detection rate in hospitalized cases (Hosp and UCI), with higher frequencies in adults older than 45. Influenza B,detected in higher proportion in outpatients, was frequently relatedwith influenza cases in younger age groups: 0-4 and 5-14 years old. Conclusions: This study highlights the correlation of theinfluenza virus type/subtype that circulates in each season with the possible need for hospitalization and intensive care in special groups of the population. Circulation of influenza A subtypes can cause more frequentdisease in individuals older than 45, with need of hospitalization including intensive care. On the other hand, influenza B is more frequently associated with less severe cases and with infection in children and younger adults. Influenza B circulation might predict lower number of hospitalizations.The identification of influenza type in circulation,byPLNID ineach season, could guide action planning measures in population health care.info:eu-repo/semantics/publishedVersio

SARS-CoV-2 introductions and early dynamics of the epidemic in Portugal

Genomic surveillance of SARS-CoV-2 in Portugal was rapidly implemented by the National Institute of Health in the early stages of the COVID-19 epidemic, in collaboration with more than 50 laboratories distributed nationwide. Methods By applying recent phylodynamic models that allow integration of individual-based travel history, we reconstructed and characterized the spatio-temporal dynamics of SARSCoV-2 introductions and early dissemination in Portugal. Results We detected at least 277 independent SARS-CoV-2 introductions, mostly from European countries (namely the United Kingdom, Spain, France, Italy, and Switzerland), which were consistent with the countries with the highest connectivity with Portugal. Although most introductions were estimated to have occurred during early March 2020, it is likely that SARS-CoV-2 was silently circulating in Portugal throughout February, before the first cases were confirmed. Conclusions Here we conclude that the earlier implementation of measures could have minimized the number of introductions and subsequent virus expansion in Portugal. This study lays the foundation for genomic epidemiology of SARS-CoV-2 in Portugal, and highlights the need for systematic and geographically-representative genomic surveillance.We gratefully acknowledge to Sara Hill and Nuno Faria (University of Oxford) and Joshua Quick and Nick Loman (University of Birmingham) for kindly providing us with the initial sets of Artic Network primers for NGS; Rafael Mamede (MRamirez team, IMM, Lisbon) for developing and sharing a bioinformatics script for sequence curation (https://github.com/rfm-targa/BioinfUtils); Philippe Lemey (KU Leuven) for providing guidance on the implementation of the phylodynamic models; Joshua L. Cherry (National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health) for providing guidance with the subsampling strategies; and all authors, originating and submitting laboratories who have contributed genome data on GISAID (https://www.gisaid.org/) on which part of this research is based. The opinions expressed in this article are those of the authors and do not reflect the view of the National Institutes of Health, the Department of Health and Human Services, or the United States government. This study is co-funded by Fundação para a Ciência e Tecnologia and Agência de Investigação Clínica e Inovação Biomédica (234_596874175) on behalf of the Research 4 COVID-19 call. Some infrastructural resources used in this study come from the GenomePT project (POCI-01-0145-FEDER-022184), supported by COMPETE 2020 - Operational Programme for Competitiveness and Internationalisation (POCI), Lisboa Portugal Regional Operational Programme (Lisboa2020), Algarve Portugal Regional Operational Programme (CRESC Algarve2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF), and by Fundação para a Ciência e a Tecnologia (FCT).info:eu-repo/semantics/publishedVersio

A Crise Demográfica: um país em extinção? Atas do V Congresso Português de Demografia

Livro de Atas do V Congresso Português de Demografi

Molecular Changes In Cardiac Tissue As A New Marker To Predict Cardiac Dysfunction Induced By Radiotherapy

International audienceThe contribution of radiotherapy, per se , to late cardiotoxicity remains controversial. To clarify its impact on the development of early cardiac dysfunction, we developed an experimental model in which the hearts of rats were exposed, in a fractionated plan, to clinically relevant doses of ionizing radiation for oncological patients that undergo thoracic radiotherapy. Rat hearts were exposed to daily doses of 0.04, 0.3, and 1.2 Gy for 23 days, achieving cumulative doses of 0.92, 6.9, and 27.6 Gy, respectively. We demonstrate that myocardial deformation, assessed by global longitudinal strain, was impaired (a relative percentage reduction of &gt;15% from baseline) in a dose-dependent manner at 18 months. Moreover, by scanning electron microscopy, the microvascular density in the cardiac apex was significantly decreased exclusively at 27.6 Gy dosage. Before GLS impairment detection, several tools (qRT-PCR, mass spectrometry, and western blot) were used to assess molecular changes in the cardiac tissue. The number/expression of several genes, proteins, and KEGG pathways, related to inflammation, fibrosis, and cardiac muscle contraction, were differently expressed in the cardiac tissue according to the cumulative dose. Subclinical cardiac dysfunction occurs in a dose-dependent manner as detected by molecular changes in cardiac tissue, a predictor of the severity of global longitudinal strain impairment. Moreover, there was no dose threshold below which no myocardial deformation impairment was detected. Our findings i) contribute to developing new markers and exploring non-invasive magnetic resonance imaging to assess cardiac tissue changes as an early predictor of cardiac dysfunction; ii) should raise red flags, since there is no dose threshold below which no myocardial deformation impairment was detected and should be considered in radiation-based imaging and -guided therapeutic cardiac procedures; and iii) highlights the need for personalized clinical approaches

Linguística clínica: Modelos, avaliação e intervenção

SinopseA Linguística Clínica reúne profissionais, investigadores e estudantes de diferentes graus académicos cujo foco de trabalho é a exploração da ponte entre a Linguística e a Fonoaudiologia (na tradição brasileira) ou a Terapia da Fala (na tradição portuguesa). Tem como objetivos centrais a construção de conhecimento sobre a natureza dos desempenhos linguísticos atípicos e a preocupação constante em tornar os processos de avaliação e de intervenção em contexto clínico cada vez mais rigorosos e eficazes. O presente volume destina-se a quem estuda ou investiga aspetos relacionados com desempenhos linguísticos atípicos em países lusófonos, nomeadamente a estudantes e docentes de cursos de graduação e pós-graduação nas áreas da Terapia da Fala/ Fonoaudiologia, da Linguística, da Psicologia e da Educação. Os capítulos que integram a presente publicação estão organizados em quatro blocos temáticos. O bloco inicial tem como objetivo central fornecer uma perspetiva histórica dos estudos em Fonologia Clínica e em Sintaxe Clínica. O segundo centra-se em aspetos fonológicos e sua relação com a dimensão fonética da língua. O terceiro bloco integra capítulos que exploram o módulo gramatical da sintaxe, a interface gramática-pragmática e o discurso. O último bloco reúne um conjunto de investigações sobre populações específicas. Synopsis Clinical Linguistics brings together professionals, researchers and students in different academic degrees focused on the bridge between Linguistics and Speech and Language Therapy. The main purpose is to display knowledge on the nature of atypical linguistic performances and to make the assessment and intervention processes increasingly rigorous and effective in the clinical context.This volume is intended for those who study or investigate aspects related to atypical linguistic performance in Portuguese-speaking countries, namely for students and teachers of undergraduate and postgraduate courses in the areas of Speech and Language Therapy, Linguistics, Psychology and Education. The chapters that make up this publication are organized into four thematic blocks. The main objective of the initial block is to provide a historical perspective of studies in Clinical Phonology and Clinical Syntax. The second block focuses on phonological aspects and their relationship with the phonetic dimension of the language. The third one includes chapters that explore the grammatical module of syntax, the grammar-pragmatic interface and discourse. The last block brings together a set of investigations on specific populations

Linguística clínica: Modelos, avaliação e intervenção

SinopseA Linguística Clínica reúne profissionais, investigadores e estudantes de diferentes graus académicos cujo foco de trabalho é a exploração da ponte entre a Linguística e a Fonoaudiologia (na tradição brasileira) ou a Terapia da Fala (na tradição portuguesa). Tem como objetivos centrais a construção de conhecimento sobre a natureza dos desempenhos linguísticos atípicos e a preocupação constante em tornar os processos de avaliação e de intervenção em contexto clínico cada vez mais rigorosos e eficazes. O presente volume destina-se a quem estuda ou investiga aspetos relacionados com desempenhos linguísticos atípicos em países lusófonos, nomeadamente a estudantes e docentes de cursos de graduação e pós-graduação nas áreas da Terapia da Fala/ Fonoaudiologia, da Linguística, da Psicologia e da Educação. Os capítulos que integram a presente publicação estão organizados em quatro blocos temáticos. O bloco inicial tem como objetivo central fornecer uma perspetiva histórica dos estudos em Fonologia Clínica e em Sintaxe Clínica. O segundo centra-se em aspetos fonológicos e sua relação com a dimensão fonética da língua. O terceiro bloco integra capítulos que exploram o módulo gramatical da sintaxe, a interface gramática-pragmática e o discurso. O último bloco reúne um conjunto de investigações sobre populações específicas. Synopsis Clinical Linguistics brings together professionals, researchers and students in different academic degrees focused on the bridge between Linguistics and Speech and Language Therapy. The main purpose is to display knowledge on the nature of atypical linguistic performances and to make the assessment and intervention processes increasingly rigorous and effective in the clinical context.This volume is intended for those who study or investigate aspects related to atypical linguistic performance in Portuguese-speaking countries, namely for students and teachers of undergraduate and postgraduate courses in the areas of Speech and Language Therapy, Linguistics, Psychology and Education. The chapters that make up this publication are organized into four thematic blocks. The main objective of the initial block is to provide a historical perspective of studies in Clinical Phonology and Clinical Syntax. The second block focuses on phonological aspects and their relationship with the phonetic dimension of the language. The third one includes chapters that explore the grammatical module of syntax, the grammar-pragmatic interface and discourse. The last block brings together a set of investigations on specific populations

Linguística clínica: Modelos, avaliação e intervenção

SinopseA Linguística Clínica reúne profissionais, investigadores e estudantes de diferentes graus académicos cujo foco de trabalho é a exploração da ponte entre a Linguística e a Fonoaudiologia (na tradição brasileira) ou a Terapia da Fala (na tradição portuguesa). Tem como objetivos centrais a construção de conhecimento sobre a natureza dos desempenhos linguísticos atípicos e a preocupação constante em tornar os processos de avaliação e de intervenção em contexto clínico cada vez mais rigorosos e eficazes. O presente volume destina-se a quem estuda ou investiga aspetos relacionados com desempenhos linguísticos atípicos em países lusófonos, nomeadamente a estudantes e docentes de cursos de graduação e pós-graduação nas áreas da Terapia da Fala/ Fonoaudiologia, da Linguística, da Psicologia e da Educação. Os capítulos que integram a presente publicação estão organizados em quatro blocos temáticos. O bloco inicial tem como objetivo central fornecer uma perspetiva histórica dos estudos em Fonologia Clínica e em Sintaxe Clínica. O segundo centra-se em aspetos fonológicos e sua relação com a dimensão fonética da língua. O terceiro bloco integra capítulos que exploram o módulo gramatical da sintaxe, a interface gramática-pragmática e o discurso. O último bloco reúne um conjunto de investigações sobre populações específicas. Synopsis Clinical Linguistics brings together professionals, researchers and students in different academic degrees focused on the bridge between Linguistics and Speech and Language Therapy. The main purpose is to display knowledge on the nature of atypical linguistic performances and to make the assessment and intervention processes increasingly rigorous and effective in the clinical context.This volume is intended for those who study or investigate aspects related to atypical linguistic performance in Portuguese-speaking countries, namely for students and teachers of undergraduate and postgraduate courses in the areas of Speech and Language Therapy, Linguistics, Psychology and Education. The chapters that make up this publication are organized into four thematic blocks. The main objective of the initial block is to provide a historical perspective of studies in Clinical Phonology and Clinical Syntax. The second block focuses on phonological aspects and their relationship with the phonetic dimension of the language. The third one includes chapters that explore the grammatical module of syntax, the grammar-pragmatic interface and discourse. The last block brings together a set of investigations on specific populations