203 research outputs found
Noise characterization of an Optical Frequency Comb using Offline Cross-Correlation
Using an offline cross-correlation technique, we have analyzed the noise
behavior of a new type of optical frequency comb (OFC), which is carrier
envelope offset (CEO) free by configuration, due to difference frequency
generation. In order to evaluate the instrument's ultimate noise floor, the
phase and amplitude noise of a stabilized OFC are measured simultaneously using
two analog-to-digital converters. Carrier recovery and phase detection are done
by post-processing, eliminating the need for external phase-locked loops and
complex calibration techniques. In order to adapt the measurement noise floor
and the number of averages used in cross correlation, an adaptive frequency
resolution for noise measurement is applied. Phase noise results are in
excellent agreement with measurements of the fluctuations of the repetition
frequency of the OFC obtained from optical signal
Pluralité des références spatiales et sociales pour les acteurs d'un contrat de rivière
National audienceRiver contracts lead smoothly stakeholders in a watershed to share points of view and enhance the emergence of collective and coherent projects.With a methodology based on collective decision support experirnents, we have interviewed a set of stakeholders of Orb Valley River Contract.This shows a variability of relevant spaces within our stakeholders sarnple, according to their physical location within or outside the basin, as well as according to their domain of action. These differences are not only based on zoning but also on the relevance of the basin as the cornmon space.As from the social point of view, embedded actors are perceived more through the local conséquences of their actions than through actual interactions. This enhance issues of coherence and conflicts. Orb valley institution seems the main coordination place.Les contrats de rivière amènent d'une manière assez souple les acteurs concernés par la gestion de l'eau sur un bassin versant à partager des points de vue et favorisent l'émergence de projets communs et cohérents. A partir d'expériences en aide à la décision collective, nous avons mené un travail d'enquêtes auprès d'acteurs du Contrat de Rivière de l'Orb. Il en ressort une variabilité des espaces de référence parmi les acteurs interviewés, selon leur localisation physique à l'intérieur ou à l'extérieur du bassin versant, et selon le rayonnement de leur activité (local ou global). Cette variabilité relève non seulement du découpage du même espace d'ensemble, le bassin versant, mais aussi de sa pertinence. Les acteurs, quant à eux, sont plus perçus à travers les conséquences locales de leurs actions que par de réelles interactions, d'où des problèmes de cohérence et de conflits perçus entre ces actions. Le syndicat mixte de la vallée de l'Orb semble le principal lieu de coordination
Aromatic oligoamide foldamers as versatile scaffolds for induced circularly polarized luminescence at adjustable wavelengths
International audienceQuinoline oligoamide foldamers appended with non-chiral fluorophores and derivatized with a camphanyl chiral inducer display strong chiroptical properties at tunable wavelengths as proved by CD and CPL spectroscopies. Induced CPL activity with high luminescence dissymmetry factors was observed in the visible range at wavelengths specific to the fluorophores
Org. Chem. Front.
The synthesis and characterization of an original π-extended cationic azahelicene is reported. The phenanthrene-fused aza[7]helicene derivative encompasses a total of ten aromatic fused rings leading to a dissymmetric yet helically folded structure, as revealed by NMR and X-ray diffraction analyses. The polyaromatic and cationic nature of the new azahelicenium makes it soluble in both organic and aqueous media, which allowed photophysical studies in solvents of different polarities. The extended chromophoric species demonstrates a broad absorption over the whole visible range and orange-red fluorescence emission. Chiral resolution of the racemate was performed subsequently, affording two optically pure and configurationally stable azahelicenium enantiomers. Multi-band circular dichroism and long-wavelength circularly polarized emission were observed, associated with remarkable absorption and luminescence dissymmetry factors, both in organic and aqueous media.Program Initiative d’Excellenc
Smart Phone, Smart Science: How the Use of Smartphones Can Revolutionize Research in Cognitive Science
Investigating human cognitive faculties such as language, attention, and memory most often relies on testing small and homogeneous groups of volunteers coming to research facilities where they are asked to participate in behavioral experiments. We show that this limitation and sampling bias can be overcome by using smartphone technology to collect data in cognitive science experiments from thousands of subjects from all over the world. This mass coordinated use of smartphones creates a novel and powerful scientific “instrument” that yields the data necessary to test universal theories of cognition. This increase in power represents a potential revolution in cognitive science
Prime Focus Spectrograph (PFS) for the Subaru Telescope: Overview, recent progress, and future perspectives
PFS (Prime Focus Spectrograph), a next generation facility instrument on the
8.2-meter Subaru Telescope, is a very wide-field, massively multiplexed,
optical and near-infrared spectrograph. Exploiting the Subaru prime focus, 2394
reconfigurable fibers will be distributed over the 1.3 deg field of view. The
spectrograph has been designed with 3 arms of blue, red, and near-infrared
cameras to simultaneously observe spectra from 380nm to 1260nm in one exposure
at a resolution of ~1.6-2.7A. An international collaboration is developing this
instrument under the initiative of Kavli IPMU. The project is now going into
the construction phase aiming at undertaking system integration in 2017-2018
and subsequently carrying out engineering operations in 2018-2019. This article
gives an overview of the instrument, current project status and future paths
forward.Comment: 17 pages, 10 figures. Proceeding of SPIE Astronomical Telescopes and
Instrumentation 201
ALK germline mutations in patients with neuroblastoma: a rare and weakly penetrant syndrome
Neuroblastic tumours may occur in a predisposition context. Two main genes are involved: PHOX2B, observed in familial cases and frequently associated with other neurocristopathies (Ondine's and Hirschsprung's disease); and ALK, mostly in familial tumours. We have assessed the frequency of mutations of these two genes in patients with a presumable higher risk of predisposition. We sequenced both genes in 26 perinatal cases (prebirth and o1 month of age, among which 10 were multifocal), 16 multifocal postnatal (41 month) cases, 3 pairs of affected relatives and 8 patients with multiple malignancies. The whole coding sequences of the two genes were analysed in tumour and/or constitutional DNAs. We found three ALK germline mutations, all in a context of multifocal tumours. Two mutations (T1151R and R1192P) were inherited and shared by several unaffected patients, thus illustrating an incomplete penetrance. Younger age at tumour onset did not seem to offer a relevant selection criterion for ALK analyses. Conversely, multifocal tumours might be the most to benefit from the genetic screening. Finally, no PHOX2B germline mutation was found in this series. In conclusion, ALK deleterious mutations are rare events in patients with a high probability of predisposition. Other predisposing genes remain to be discovered
Progress with the Prime Focus Spectrograph for the Subaru Telescope: a massively multiplexed optical and near-infrared fiber spectrograph
The Prime Focus Spectrograph (PFS) is an optical/near-infrared multi-fiber
spectrograph with 2394 science fibers, which are distributed in 1.3 degree
diameter field of view at Subaru 8.2-meter telescope. The simultaneous wide
wavelength coverage from 0.38 um to 1.26 um, with the resolving power of 3000,
strengthens its ability to target three main survey programs: cosmology,
Galactic archaeology, and galaxy/AGN evolution. A medium resolution mode with
resolving power of 5000 for 0.71 um to 0.89 um also will be available by simply
exchanging dispersers. PFS takes the role for the spectroscopic part of the
Subaru Measurement of Images and Redshifts project, while Hyper Suprime-Cam
works on the imaging part. To transform the telescope plus WFC focal ratio, a
3-mm thick broad-band coated glass-molded microlens is glued to each fiber tip.
A higher transmission fiber is selected for the longest part of cable system,
while one with a better FRD performance is selected for the fiber-positioner
and fiber-slit components, given the more frequent fiber movements and tightly
curved structure. Each Fiber positioner consists of two stages of
piezo-electric rotary motors. Its engineering model has been produced and
tested. Fiber positioning will be performed iteratively by taking an image of
artificially back-illuminated fibers with the Metrology camera located in the
Cassegrain container. The camera is carefully designed so that fiber position
measurements are unaffected by small amounts of high special-frequency
inaccuracies in WFC lens surface shapes. Target light carried through the fiber
system reaches one of four identical fast-Schmidt spectrograph modules, each
with three arms. Prototype VPH gratings have been optically tested. CCD
production is complete, with standard fully-depleted CCDs for red arms and
more-challenging thinner fully-depleted CCDs with blue-optimized coating for
blue arms.Comment: 14 pages, 12 figures, submitted to "Ground-based and Airborne
Instrumentation for Astronomy V, Suzanne K. Ramsay, Ian S. McLean, Hideki
Takami, Editors, Proc. SPIE 9147 (2014)
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