23 research outputs found
Joint venture internacional
Este artigo tem como principal objetivo apresentar as parcerias realizadas entre empresas de diferentes países denominadas, joint ventures internacionais e seus principais benefícios, bem como apresentar de que maneira a joint venture pode ser utilizada como estratégia de crescimento em todas empresas parceiras. A primeira parte é sobre um pequeno histórico de como surgiu o termo e os conceitos do termo segundo diversos autores. Este trabalho apresenta-se muito rico em conceitos, pois foram pesquisados diversas obras dos maiores autores do assunto. O artigo apresenta um estudo de caso da empresa Nova Oferta distribuidora, que realiza uma joint venture com uma empresa chinesa para a fabricação de seus produtos, após o estudo de caso é feita uma relação dos conceitos apresentados e como eles são vistos na pratica. Conclui-se que o estudo de caso conseguiu ilustrar as situações que envolvem uma joint venture internacional, como a formação da parceria e o acesso a novos mercados por ambas as partes.
Diversity, taphonomy and palaeoecology of an angiosperm flora from the cretaceous (Cenomanian-Coniacian) in Southern Patagonia, Argentina
This paper describes the diversity, taphonomy and palaeoecology of angiosperm leaves that dominate a palaeoflora of Cretaceous (Cenomanian-Coniacian) age from the Mata Amarilla Formation in the Austral Basin, south-west Patagonia, Argentina. Twelve morphotypes of angiosperm leaves are recognized based on foliar morphotype analysis of more than 500 specimens. These were divided into six morphological groups based on major architectural patterns. The relative dominance of these morphotypes, mode of preservation and relationship with sedimentary facies were evaluated from two levels within the formation. This analysis identified two different plant palaeocommunities. The lower, María Elena, level (MEL) was deposited in a marine coastal area on a subaerial delta plain; the dominant angiosperm morphotypes preserved in it are group 1 (MA100) and group 2 (MA101, 102); morphotypes MA109 and 110 are scarce but exclusive to this level. The upper, Mata Amarilla, level (MAL), accumulated inland in flood-plain environments; the most abundant angiosperm morphotypes are groups 3 (MA103-105), 4 (MA106) and 1 (MA100); morphotypes MA103-105 and 108 are exclusive to this level. Comparisons with other floras of similar age from Antarctica, Australia and New Zealand indicate that the Mata Amarilla flora has a slightly higher morphological diversity of angiosperm leaves, providing the first evidence for an angiosperm-dominated early Late Cretaceous macroflora in south-west Gondwana.Facultad de Ciencias Naturales y Muse
Diversity, taphonomy and palaeoecology of an angiosperm flora from the cretaceous (Cenomanian-Coniacian) in Southern Patagonia, Argentina
This paper describes the diversity, taphonomy and palaeoecology of angiosperm leaves that dominate a palaeoflora of Cretaceous (Cenomanian-Coniacian) age from the Mata Amarilla Formation in the Austral Basin, south-west Patagonia, Argentina. Twelve morphotypes of angiosperm leaves are recognized based on foliar morphotype analysis of more than 500 specimens. These were divided into six morphological groups based on major architectural patterns. The relative dominance of these morphotypes, mode of preservation and relationship with sedimentary facies were evaluated from two levels within the formation. This analysis identified two different plant palaeocommunities. The lower, María Elena, level (MEL) was deposited in a marine coastal area on a subaerial delta plain; the dominant angiosperm morphotypes preserved in it are group 1 (MA100) and group 2 (MA101, 102); morphotypes MA109 and 110 are scarce but exclusive to this level. The upper, Mata Amarilla, level (MAL), accumulated inland in flood-plain environments; the most abundant angiosperm morphotypes are groups 3 (MA103-105), 4 (MA106) and 1 (MA100); morphotypes MA103-105 and 108 are exclusive to this level. Comparisons with other floras of similar age from Antarctica, Australia and New Zealand indicate that the Mata Amarilla flora has a slightly higher morphological diversity of angiosperm leaves, providing the first evidence for an angiosperm-dominated early Late Cretaceous macroflora in south-west Gondwana.Facultad de Ciencias Naturales y Muse
Diversity, taphonomy and palaeoecology of an angiosperm flora from the cretaceous (Cenomanian-Coniacian) in Southern Patagonia, Argentina
This paper describes the diversity, taphonomy and palaeoecology of angiosperm leaves that dominate a palaeoflora of Cretaceous (Cenomanian-Coniacian) age from the Mata Amarilla Formation in the Austral Basin, south-west Patagonia, Argentina. Twelve morphotypes of angiosperm leaves are recognized based on foliar morphotype analysis of more than 500 specimens. These were divided into six morphological groups based on major architectural patterns. The relative dominance of these morphotypes, mode of preservation and relationship with sedimentary facies were evaluated from two levels within the formation. This analysis identified two different plant palaeocommunities. The lower, María Elena, level (MEL) was deposited in a marine coastal area on a subaerial delta plain; the dominant angiosperm morphotypes preserved in it are group 1 (MA100) and group 2 (MA101, 102); morphotypes MA109 and 110 are scarce but exclusive to this level. The upper, Mata Amarilla, level (MAL), accumulated inland in flood-plain environments; the most abundant angiosperm morphotypes are groups 3 (MA103-105), 4 (MA106) and 1 (MA100); morphotypes MA103-105 and 108 are exclusive to this level. Comparisons with other floras of similar age from Antarctica, Australia and New Zealand indicate that the Mata Amarilla flora has a slightly higher morphological diversity of angiosperm leaves, providing the first evidence for an angiosperm-dominated early Late Cretaceous macroflora in south-west Gondwana.Facultad de Ciencias Naturales y Muse
A influência da torcida na motivação de jogadores de futebol profissional
ABSTRACTThe influence of the twist in the motivation of professional the footballIntroduction: motivation is undoubtedly very important for the development of tasks, not only for athletes, but to any person who has duties to perform. In professional football athletes the motivation can be an important factor for their performance, and the fans are an important motivating tool. Objective: The aim of this study is to analyze the influence of fans in the performance of professional football players. Materials and methods: a questionnaire with structured and semi structured questions, for eleven professional footballers in order to verify the influence of the fans in their performances. Results: Analyzing the results, it should be noted that most of the players feel motivated when hired by a team that has great fans and also when they play with the fans in its favor. Also, it turns out that if hired by a team with small fans, it do not let them unmotivated, just makes no difference. Play with fans against showed that has no major change in the motivation of those players. Discussion: many authors have written books and presented studies which confirm that motivation is undoubtedly very important for the athlete to have a better performance. This article confirms these results, showing that the extrinsic motivation, especially the fans in the case of professional football players, has great motivational factor. Conclusion: the fans are important to motivate most players interviewed, while fans against does not significantly change the motivation.Introdução: A motivação é sem dúvida muito importante para o desenvolvimento de tarefas, não só para desportistas, mas para qualquer pessoa que tenha tarefas a realizar. Em atletas de futebol profissional a motivação pode ser um fator importante para seu rendimento, sendo a torcida um importante instrumento motivador. Objetivo: O objetivo deste trabalho é analisar a influência da torcida na performance de jogadores de futebol profissional. Materiais e métodos: Foi aplicado um questionário contendo questões estruturadas e semiestruturadas, a onze jogadores profissionais de futebol a fim de verificar a influência da torcida em sua performance. Resultados: Analisando os resultados, nota-se que a maioria dos jogadores se sentem motivados quando contratados por uma equipe que tem grande torcida e também quando jogam com a torcida a seu favor. Também, verifica-se que se contratados por uma equipe com torcida pequena, não os deixa desmotivados, apenas não faz diferença. Jogar com torcida contra mostrou que não tem grande alteração na motivação desses jogadores. Discussão: Muitos autores já escreveram livros e apresentaram estudos que confirmam que a motivação é sem dúvida muito importante para que o atleta tenha um desempenho melhor. Este artigo vem de encontro a esses resultados, mostrando que a motivação extrínseca, principalmente a torcida no caso de jogadores de futebol profissional, tem grande fator motivacional. Conclusão: A torcida a favor deixa motivada a maioria dos jogadores entrevistados, enquanto a contra não oferece mudança significativa.
First Cenomanian record of insects in the Southern Hemisphere, with Perforissidae (Fulgoroidea) and Cupedidae (Coleoptera) from Southern Patagonia, Argentina
The discovery of the southernmost world record (49.5S) of a Late Cretaceous insect fauna and plant-insect interactions is reported herein. The new locality is from the middle Cenomanian lacustrine deposits of the Mata Amarilla Formation belonging to the Austral foreland Basin, southwest Patagonia, Argentina. A first trip to the locality yielded few specimens of Coleoptera, among them an Archostemata: Cupedidae, and also a tiny specimen of Fulgoroidea: Perforissidae represented by Aonikenkissus zamunerae gen. et sp. nov. The Perforissidae were previously recorded from the Berriasian (?)-Barremian, Aptian, Albian, Turonian and Santonian in the Northern Hemisphere. The new species represents the first record of Perforissidae for South America and for the whole Southern Hemisphere. The new record suggests that the Perforissidae had a broader biogeographical distribution, and seem to have been cosmopolitan in the mid-Cretaceous. The Cupedidae reported herein is the first record for the Cenomanian and the first record of the genus Zygadenia in South America. Insect traces found in the same strata are made in an angiosperm palmatilobed leaf and correspond to a piercing and sucking type of damage. This type of damage is compared to recent stipples and to isolated piercings.Fil: Petrulevicius, Julian Fernando. Universidad Nacional de la Plata. Facultad de Ciencias Naturales y Museo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Varela, Augusto Nicolas. Universidad Nacional de la Plata. Facultad de Ciencias Naturales y Museo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigaciones Geológicas (i); ArgentinaFil: Iglesias, Ari. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Patagonia Norte. Instituto de Investigación En Biodiversidad y Medioambiente; Argentina. Universidad Nacional del Comahue; ArgentinaFil: Zamuner, Alba Berta. Universidad Nacional de la Plata. Facultad de Ciencias Naturales y Museo. Area Paleobotánica; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Poire, Daniel Gustavo. Universidad Nacional de la Plata. Facultad de Ciencias Naturales y Museo; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico La Plata. Centro de Investigaciones Geológicas (i); Argentin
Identification of markers for the presence of lymph nodes metastasis in patients with oral squamous cell carcinomas
Universidade Federal de São Paulo, São Paulo, BrazilHosp Canc Barretos, Barretos, BrazilUniversidade Federal de São Paulo, São Paulo, BrazilWeb of Scienc
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Clinical and genomic characterization of chemoradiation-resistant HPV-positive oropharyngeal squamous cell carcinoma.
INTRODUCTION: Most patients with HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) have an excellent response to chemoradiation, and trials are now investigating de-escalated treatment. However, up to 25% of patients with HPV-positive OPSCC will experience recurrence, and up to 5% will even progress through primary treatment. Currently, there are no molecular markers to identify patients with poor prognosis who would be harmed by de-escalation. Herein we report the clinical and genomic characteristics of persistent HPV-positive OPSCC after definitive platinum-based chemoradiation therapy. METHODS: Patients with HPV-positive OPSCC treated with curative intent platinum-based chemoradiation between 2007 and 2017 at two institutions and with a persistent locoregional disease were included. We evaluated clinical characteristics, including smoking status, age, stage, treatment, and overall survival. A subset of five patients had tissue available for targeted exome DNA sequencing and RNA sequencing. Genomic analysis was compared to a previously published cohort of 47 treatment-responsive HPV+ OPSCC tumors after batch correction. Mutational landscape, pathway activation, and OncoGPS tumor states were employed to characterize these tumors. RESULTS: Ten patients met the inclusion criteria. The tumor and nodal stages ranged from T1 to T4 and N1 to N2 by AJCC 8th edition staging. All patients were p16-positive by immunohistochemistry, and eight with available in situ hybridization were confirmed to be HPV-positive. The 1-year overall survival from the time of diagnosis was 57%, and the 2-year overall survival was 17%. TP53 mutations were present in three of five (60%) persistent tumors compared to 2% (one of 47) of treatment-responsive HPV-positive tumors (p = 0.008). Other genes with recurrent mutations in persistent HPV-positive OPSCC tumors were NF1, KMT2D, PIK3C2B, and TFGBR2. Compared to treatment-responsive HPV-positive tumors, persistent tumors demonstrated activation of DNA Repair and p53, EMT, MYC, SRC, and TGF-beta signaling pathways, with post-treatment samples demonstrating significant activation of the PI3K-EMT-Stem pathways compared to pretreatment samples. CONCLUSION: Chemoradiation-resistant HPV-positive OPSCC occurs infrequently but portends a poor prognosis. These tumors demonstrate higher rates of p53 mutation and activation of MYC, SRC, and TGF-beta pathways. A comparison of tumors before and after treatment demonstrates PI3K-EMT-Stem pathways post-treatment in HPV-positive tumors with persistent disease after platinum-based chemoradiation