Estudio en Microcosmos de los Efectos del Plaguicida Trifloxistrobina sobre el Plancton

El presente trabajo tiene como objetivo estudiar el impacto del fungicida Trifloxistrobina sobre el plancton. Se realizaron ensayos de toxicidad a nivel de microcosmos, utilizando 32 tanques inoculados con plancton. Las concentraciones de Trifloxistrobina aplicadas fueron de: 0,01 mg/L (C1); 0,1 mg/L (C2) y 1 mg/L (C3) y dos controles (Co). Los muestreos del plancton se realizaron a las 3, 6, 24 y 72 horas. Se midieron y analizaron variables biológicas y físico-químicas in situ y en laboratorio. Los análisis estadísticos no dieron diferencias significativas para la abundancia del fitoplancton y fueron significativas para el zooplancton a la mayor concentración.The effect of pesticide Trifloxistrobin on plankton: a microcosm study The present work aims to study the impact of pesticide Trifloxistrobin on plankton. Toxicity tests were conducted at microcosm level, using 32 tanks inoculated with plankton. The concentrations of Trifloxistrobin applied were: 0,01 mg/L (C1); 0,1 mg/L (C2) y 1 mg/L (C3) and two controls (Co). Plankton samples were taken at 3, 6, 24 and 72 hours. Biological and physicochemical variables were measured and analyzed in situ and in laboratory. The statistical analyses did not give remarkable differences for phytoplankton, whereas these abundance differences were significant for the zooplankton at the highest concentration.Fil: Fernandez, Viviana Claudia. Universidad Nacional del Litoral. Facultad de Humanidades y Ciencias. Departamento de Cs.naturales. Laboratorio de Bioensayos; ArgentinaFil: Polla, Wanda. Universidad Nacional del Litoral. Facultad de Humanidades y Ciencias. Departamento de Cs.naturales. Laboratorio de Bioensayos; ArgentinaFil: Lorenzatti, Eduardo Antonio. Universidad Nacional del Litoral. Facultad de Bioquimica y Ciencias Biologicas. Escuela Superior de Sanidad; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Santa Fe. Instituto de Desarrollo Tecnológico para la Industria Química (i); Argentin

El uso del software Derive en procesos de enseñanza-aprendizaje de la geometría analítica y vectores de alumnos de nivel universitario.

Se investigó El uso del software DERIVE en procesos de enseñanza – aprendizaje de la Geometría Analítica y Vectores de alumnos de nivel universitario matriculado en el primer año de la carrera de Ingeniería Civil. El trabajo se planteó con un enfoque cuantitativo, alcance descriptivo y de diseño no experimental, se apoyó en una amplia revisión bibliográfica. La problemática del trabajo consiste en el bajo nivel que demuestran los alumnos del primer año de la carrera de Ingeniería Civil en la resolución de problemas de geometría analítica observado por el docente investigador. El trabajo tiene como propósito Determinar los efectos del uso del software DERIVE en los procesos de enseñanza-aprendizaje de la Geometría analítica y Vectores de alumnos del Primer Curso de la carrera de Ingeniería Civil de la FACET-UNC. La hipótesis planteada consiste en: El uso del software DERIVE mejora la interactividad, genera experiencia más ajustadas a las necesidades individuales y mejora la capacidad de resolución de problemas de Geometría Analítica y Vectores, de los estudiantes del primer año de la carrera de Ingeniería Civil de la FACET-UNC. La muestra está constituida por 19 estudiantes del grupo control y 19 estudiantes del grupo uso de derive, la muestra para el grupo control se creó a voluntad de los propios alumnos. Para el análisis de los datos e interpretación de los resultados se utiliza tabla de frecuencias y gráficos estadísticos, además de la comparación de medias entre dos poblaciones mediante la herramienta estadística T de Student. En conjunto, con el resultado obtenido mediante la comparación de medias entre las dos poblaciones en estudio, se pudo contrastar aceptando la hipótesis de investigación planteada, es decir, El uso del software DERIVE mejora la interactividad, genera experiencia más ajustadas a las necesidades individuales y mejora la capacidad de resolución de problemas de Geometría Analítica y Vectores, de los estudiantes del primer año de la carrera de Ingeniería Civil de la FACET-UNC.CONACYT - Consejo Nacional de Ciencia y TecnologíaPROCIENCI

Maximum equilibrium prevalence of mosquito-borne microparasite infections in humans.

To determine the maximum equilibrium prevalence of mosquito-borne microparasitic infections, this paper proposes a general model for vector-borne infections which is flexible enough to comprise the dynamics of a great number of the known diseases transmitted by arthropods. From equilibrium analysis, we determined the number of infected vectors as an explicit function of the model's parameters and the prevalence of infection in the hosts. From the analysis, it is also possible to derive the basic reproduction number and the equilibrium force of infection as a function of those parameters and variables. From the force of infection, we were able to conclude that, depending on the disease's structure and the model's parameters, there is a maximum value of equilibrium prevalence for each of the mosquito-borne microparasitic infections. The analysis is exemplified by the cases of malaria and dengue fever. With the values of the parameters chosen to illustrate those calculations, the maximum equilibrium prevalence found was 31% and 0.02% for malaria and dengue, respectively. The equilibrium analysis demonstrated that there is a maximum prevalence for the mosquito-borne microparasitic infections

Neurosurgery of the peripheral nervous system: Entrapment syndromes of the brachial plexus

[No abstract available

A Methodology to Create 3D Body Models in Motion

[EN] Size, shape and posture are fundamental features of digital human models (DHM) to obtain accurate virtual simulations of the ergonomics of products and environments. Research on 3D body scanning, processing and modelling have enabled the generation of avatars representing specific populations and morphotypes in standing and seated postures being the basis to define size and shape of DHM. Posture is implemented with biomechanical models of the human movement. Most of the research is focused on posture control and movement tracking to analyze the variability in different contexts (e.g. driving, performing a working task). Motion capture technology used for this purpose, requires a limited number of sensors or reflective markers attached to the body according to the definition of body segments. 3D body scanning and motion capture are both technologies currently used to analyze human body shape and biomechanics to apply it to enhance digital human models. These technologies may converge on the so-called temporal 3D scanners or 4D scanners, a new technology recently developed to scan the body in motion. With this technology, it is possible to obtain sequences of dense 3D point clouds representing the movement of the body. In this paper, a novel methodology to create realistic 3D body models in motion is proposed. This method is supported by a new 4D scanning system (Move 4D) and a data driven-model. Move4D is a modular photogrammetry-based 4D scanning system. It consists of a set of 12 synchronized modules to scan full bodies with texture in motion. It can capture up to 180 fps with a resolution of 2 mm. The algorithms have been conceived and optimized to automatically process the series of raw point clouds captured. They rely on a data-driven body model including shape, pose and soft-tissue deformation trained with a large database and a deep learning model. The process is fully automatic and does not require any interactive landmarking or revision. The 3D outcome of this methodology is one noise-and artefact-free watertight mesh per frame and a model of shape, pose and soft-tissue that can be rigged with a 23-joint skeleton. This type of outcome permits their use for many applications such as simulations, augmented and virtual reality (AR/VR) or biomechanical analysis purposes.The research presented in this paper have been developed within the projects IMDEEA/2020/85 and MDEEA/2020/87. Funding requested to Instituto Valenciano de Competitividad Empresarial (IVACE), call for proposals 2020 for Technology Centers of the Comunitat Valenciana, co-funded by ERDF Funds, EU Operational Program of the Comunitat Valenciana 2014-2020.Parrilla Bernabé, E.; Ruescas, A.; Solves, J.; Ballester Fernandez, A.; Nacher Fernandez, B.; Alemany Mut, MS.; Garrido Jaen, JD. (2020). A Methodology to Create 3D Body Models in Motion. Springer. 309-314. https://doi.org/10.1007/978-3-030-51064-0_39S309314Scataglini, S., Paul, G.: DHM and Posturography. Academic Press, London (2019)Zakaria, N., Gupta, D.: Anthropometry, Apparel Sizing and Design. Woodhead Publishing, Cambridge (2019)Liberadzki, P., Adamczyk, M., Witkowski, M., Sitnik, R.: Structured-light-based system for shape measurement of the human body in motion. Sensors 18, 2827 (2018). https://doi.org/10.3390/s18092827Parrilla, E., Ballester, A., Parra, P., Ruescas, A., Uriel, J., Garrido, D., Alemany, S.: MOVE 4D: accurate high-speed 3D body models in motion. In: Proceedings of 3DBODY.TECH 2019, Lugano, Switzerland, 22–23 October 2019, pp. 30–32 (2019). https://doi.org/10.15221/19.03

Estimating the prevalence of infectious diseases from under-reported age-dependent compulsorily notification databases.

BACKGROUND: National or local laws, norms or regulations (sometimes and in some countries) require medical providers to report notifiable diseases to public health authorities. Reporting, however, is almost always incomplete. This is due to a variety of reasons, ranging from not recognizing the diseased to failures in the technical or administrative steps leading to the final official register in the disease notification system. The reported fraction varies from 9 to 99% and is strongly associated with the disease being reported. METHODS: In this paper we propose a method to approximately estimate the full prevalence (and any other variable or parameter related to transmission intensity) of infectious diseases. The model assumes incomplete notification of incidence and allows the estimation of the non-notified number of infections and it is illustrated by the case of hepatitis C in Brazil. The method has the advantage that it can be corrected iteratively by comparing its findings with empirical results. RESULTS: The application of the model for the case of hepatitis C in Brazil resulted in a prevalence of notified cases that varied between 163,902 and 169,382 cases; a prevalence of non-notified cases that varied between 1,433,638 and 1,446,771; and a total prevalence of infections that varied between 1,597,540 and 1,616,153 cases. CONCLUSIONS: We conclude that the model proposed can be useful for estimation of the actual magnitude of endemic states of infectious diseases, particularly for those where the number of notified cases is only the tip of the iceberg. In addition, the method can be applied to other situations, such as the well-known underreported incidence of criminality (for example rape), among others

A simple method to select high superovulatory responder goats

In most female mammals, a common drawback to multiple ovulation embryo transfer programs is the variability in the superovulatory response to the multidose pFSH treatment. The aim of the present study was to identify embryo donor goats based on their response to superovulation before the performance of a high-cost hormonal treatment, as we have previously done in sheep. To this end, we evaluated the number of ovulations obtained in response to the administration of a one-shot eCG treatment and related it with the subsequent ovarian response to a multiple-dose pFSH treatment in 33 goats of the Criolla-Neuquina breed. Goats received a one-shot eCG treatment of 800 IU at the end of a 17-day progestational treatment; 9 days later, started a second 17-day progestational treatment and then received a multiple-dose pFSH treatment on days 15–17 (116 mg pFSH, in six decreasing doses). The number of corpora lutea (CL) per goat was recorded laparoscopically after both hormonal treatments. On day 8 after the second pessary removal, embryos were surgically recovered and classified by quality. Results showed a significant positive correlation between the number of CL obtained in response to the eCG and pFSH treatments (r = 0.41; y = 0.8352x + 6.9906; P 0.05). In conclusion, the recurrence rate in ovarian response between the one-shot eCG treatment and the multiple-dose pFSH treatment would confirm the existence of an “individual or intrinsic factor” of the donor goat that would respond as a high or low ovulatory responder to superovulatory treatments.Fil: Bruno Galarraga, María Macarena. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Patagonia Norte. Estación Experimental Agropecuaria San Carlos de Bariloche. Instituto de Investigaciones Forestales y Agropecuarias Bariloche. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones Forestales y Agropecuarias Bariloche; ArgentinaFil: Fernandez, Jimena. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Patagonia Norte. Estación Experimental Agropecuaria San Carlos de Bariloche. Instituto de Investigaciones Forestales y Agropecuarias Bariloche. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones Forestales y Agropecuarias Bariloche; ArgentinaFil: Lacau, Isabel María. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Biología y Medicina Experimental. Fundación de Instituto de Biología y Medicina Experimental. Instituto de Biología y Medicina Experimental; ArgentinaFil: Gonzalez Bulnes, Antonio. Universidad Cardenal Herrera; EspañaFil: Gibbons, Alejandro Eduardo. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Patagonia Norte. Estación Experimental Agropecuaria San Carlos de Bariloche. Instituto de Investigaciones Forestales y Agropecuarias Bariloche. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones Forestales y Agropecuarias Bariloche; ArgentinaFil: Cueto, Marcela Isabel. Instituto Nacional de Tecnología Agropecuaria. Centro Regional Patagonia Norte. Estación Experimental Agropecuaria San Carlos de Bariloche. Instituto de Investigaciones Forestales y Agropecuarias Bariloche. - Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Patagonia Norte. Instituto de Investigaciones Forestales y Agropecuarias Bariloche; Argentin

Fibrinogen Sevilla, a congenital dysfibrinogenemia characterized by an abnormal monomer aggregation and a defective plasmin lysis

A dysfibrinogenemia (fibrinogen Sevilla) was detected in a 64-yr-old woman with no previous history of hemorrhagic diathesis or thrombosis. Thrombin and reptilase times were prolonged. The aggregation of fibrin monomers showed a prolonged latency time with a defective slope although fibrinopeptide release and clot stabilization were found to be normal. Plasmin proteolysis was abnormal with a much slower plasmic degradation in patient's purified fibrinogen. By chromatofocussing the patient's fibrinogen showed an abnormality in pattern elution with a second peak eluting at a pH slightly more basic than the normal one (pH 5.5). Likewise, the isoelectrofocussing of purified non-reduced patient's fibrinogen in agarose gel showed an abnormal distribution in its focussed bands, especially in a group which focussed in a pI-interval between 5.20-5.85. By two-dimensional electrophoresis we did not find any abnormality in the fibrinogen-reduced chains. These results could indicate that the abnormal monomer aggregation, as well as the defective plasmin lysis, could be due to conformational aspects of fibrinogen rather than to structural defects