220 research outputs found
Integrability and Algebraic Solutions for Planar Polynomial Differential Systems with Emphasis on the Quadratic Systems
The paper is divided into two parts. In the first one we present a survey about the theory of Darboux for the integrability of polynomial differential equations
A Budding-Defective M2 Mutant Exhibits Reduced Membrane Interaction, Insensitivity To Cholesterol, And Perturbed Interdomain Coupling
Influenza A M2 is a membrane-associated protein with a C-terminal amphipathic helix that plays a cholesterol-dependent role in viral budding. An M2 mutant with alanine substitutions in the C-terminal amphipathic helix is deficient in viral scission. With the goal of providing atomic-level understanding of how the wild-type protein functions, we used a multipronged site-directed spin labeling electron paramagnetic resonance spectroscopy (SDSL-EPR) approach to characterize the conformational properties of the alanine mutant. We spin-labeled sites in the transmembrane (TM) domain and the C-terminal amphipathic helix (AH) of wild-type (WT) and mutant M2, and collected information on line shapes, relaxation rates, membrane topology, and distances within the homotetramer in membranes with and without cholesterol. Our results identify marked differences in the conformation and dynamics between the WT and the alanine mutant. Compared to WT, the dominant population of the mutant AH is more dynamic, shallower in the membrane, and has altered quaternary arrangement of the C-terminal domain. While the AH becomes more dynamic, the dominant population of the TM domain of the mutant is immobilized. The presence of cholesterol changes the conformation and dynamics of the WT protein, while the alanine mutant is insensitive to cholesterol. These findings provide new insight into how M2 may facilitate budding. We propose the AH–membrane interaction modulates the arrangement of the TM helices, effectively stabilizing a conformational state that enables M2 to facilitate viral budding. Antagonizing the properties of the AH that enable interdomain coupling within M2 may therefore present a novel strategy for anti-influenza drug design
Numerical simulation of a negative ion plasma expansion into vacuum
The expansion into vacuum of a one-dimensional, collisionless, negative ion plasma is investigated in the framework of the Vlasov–Poisson model. The basic equations are written in a ‘‘new time space’’ by use of a rescaling transformation and, subsequently, solved numerically through a fully Eulerian code. As in the case of a two species plasma, the time-asymptotic regime is found to be self-similar with the temperature decreasing as t22. The numerical results exhibit clearly the physically expected effects produced by the variation of parameters such as initial temperatures, mass ratios and charge of the negative ions
Influence of Collision Cascade Statistics on Pattern Formation of Ion-Sputtered Surfaces
Theoretical continuum models that describe the formation of patterns on
surfaces of targets undergoing ion-beam sputtering, are based on Sigmund's
formula, which describes the spatial distribution of the energy deposited by
the ion. For small angles of incidence and amorphous or polycrystalline
materials, this description seems to be suitable, and leads to the classic BH
morphological theory [R.M. Bradley and J.M.E. Harper, J. Vac. Sci. Technol. A
6, 2390 (1988)]. Here we study the sputtering of Cu crystals by means of
numerical simulations under the binary-collision approximation. We observe
significant deviations from Sigmund's energy distribution. In particular, the
distribution that best fits our simulations has a minimum near the position
where the ion penetrates the surface, and the decay of energy deposition with
distance to ion trajectory is exponential rather than Gaussian. We provide a
modified continuum theory which takes these effects into account and explores
the implications of the modified energy distribution for the surface
morphology. In marked contrast with BH's theory, the dependence of the
sputtering yield with the angle of incidence is non-monotonous, with a maximum
for non-grazing incidence angles.Comment: 12 pages, 13 figures, RevTe
Is Gravitational Lensing by Intercluster Filaments Always Negligible?
Intercluster filaments negligibly contribute to the weak lensing signal in
general relativity (GR), . In the context of
relativistic modified Newtonian dynamics (MOND) introduced by Bekenstein,
however, a single filament inclined by from the line of
sight can cause substantial distortion of background sources pointing towards
the filament's axis (); this is rigorous
for infinitely long uniform filaments, but also qualitatively true for short
filaments (Mpc), and even in regions where the projected matter
density of the filament is equal to zero. Since galaxies and galaxy clusters
are generally embedded in filaments or are projected on such structures, this
contribution complicates the interpretation of the weak lensing shear map in
the context of MOND. While our analysis is of mainly theoretical interest
providing order-of-magnitude estimates only, it seems safe to conclude that
when modeling systems with anomalous weak lensing signals, e.g. the "bullet
cluster" of Clowe et al., the "cosmic train wreck" of Abell 520 from Mahdavi et
al., and the "dark clusters" of Erben et al., filamentary structures might
contribute in a significant and likely complex fashion. On the other hand, our
predictions of a (conceptual) difference in the weak lensing signal could, in
principle, be used to falsify MOND/TeVeS and its variations.Comment: 11 pages, 6 figures, published versio
Nonlinear Dirac operator and quaternionic analysis
Properties of the Cauchy-Riemann-Fueter equation for maps between
quaternionic manifolds are studied. Spaces of solutions in case of maps from a
K3-surface to the cotangent bundle of a complex projective space are computed.
A relationship between harmonic spinors of a generalized nonlinear Dirac
operator and solutions of the Cauchy-Riemann-Fueter equation are established.Comment: Cosmetic changes onl
A direct probe of cosmological power spectra of the peculiar velocity field and the gravitational lensing magnification from photometric redshift surveys
The cosmological peculiar velocity field (deviations from the pure Hubble
flow) of matter carries significant information on dark energy, dark matter and
the underlying theory of gravity on large scales. Peculiar motions of galaxies
introduce systematic deviations between the observed galaxy redshifts z and the
corresponding cosmological redshifts z_cos. A novel method for estimating the
angular power spectrum of the peculiar velocity field based on observations of
galaxy redshifts and apparent magnitudes m (or equivalently fluxes) is
presented. This method exploits the fact that a mean relation between z_cos and
m of galaxies can be derived from all galaxies in a redshift-magnitude survey.
Given a galaxy magnitude, it is shown that the z_cos(m) relation yields its
cosmological redshift with a 1-sigma error of sigma_z~0.3 for a survey like
Euclid (~10^9 galaxies at z<~2), and can be used to constrain the angular power
spectrum of z-z_cos(m) with a high signal-to-noise ratio. At large angular
separations corresponding to l<~15, we obtain significant constraints on the
power spectrum of the peculiar velocity field. At 15<~l<~60, magnitude shifts
in the z_cos(m) relation caused by gravitational lensing magnification
dominate, allowing us to probe the line-of-sight integral of the gravitational
potential. Effects related to the environmental dependence in the luminosity
function can easily be computed and their contamination removed from the
estimated power spectra. The amplitude of the combined velocity and lensing
power spectra at z~1 can be measured with <~5% accuracy.Comment: 22 pages, 3 figures; added a discussion of systematic errors,
accepted for publication in JCA
Global Structure of Moduli Space for BPS Walls
We study the global structure of the moduli space of BPS walls in the Higgs
branch of supersymmetric theories with eight supercharges. We examine the
structure in the neighborhood of a special Lagrangian submanifold M, and find
that the dimension of the moduli space can be larger than that naively
suggested by the index theorem, contrary to previous examples of BPS solitons.
We investigate BPS wall solutions in an explicit example of M using Abelian
gauge theory. Its Higgs branch turns out to contain several special Lagrangian
submanifolds including M. We show that the total moduli space of BPS walls is
the union of these submanifolds. We also find interesting dynamics between BPS
walls as a byproduct of the analysis. Namely, mutual repulsion and attraction
between BPS walls sometimes forbid a movement of a wall and lock it in a
certain position; we also find that a pair of walls can transmute to another
pair of walls with different tension after they pass through.Comment: 42 pages, 11 figures; a few comments adde
A nonlocal connection between certain linear and nonlinear ordinary differential equations/oscillators
We explore a nonlocal connection between certain linear and nonlinear
ordinary differential equations (ODEs), representing physically important
oscillator systems, and identify a class of integrable nonlinear ODEs of any
order. We also devise a method to derive explicit general solutions of the
nonlinear ODEs. Interestingly, many well known integrable models can be
accommodated into our scheme and our procedure thereby provides further
understanding of these models.Comment: 12 pages. J. Phys. A: Math. Gen. 39 (2006) in pres
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