Rank-(n – 1) convexity and quasiconvexity for divergence free fields

The CAST experiment at CERN (European Organization of Nuclear Research) searches for axions from the sun. The axion is a pseudoscalar particle that was motivated by theory thirty years ago, with the intention to solve the strong CP problem. Together with the neutralino, the axion is one of the most promising dark matter candidates. The CAST experiment has been taking data during the last two years, setting an upper limit on the coupling of axions to photons more restrictive than from any other solar axion search in the mass range below 0.1 eV. In 2005 CAST will enter a new experimental phase extending the sensitivity of the experiment to higher axion masses. The CAST experiment strongly profits from technology developed for high energy physics and for X-ray astronomy: A superconducting prototype LHC magnet is used to convert potential axions to detectable X-rays in the 1-10 keV range via the inverse Primakoff effect. The most sensitive detector system of CAST is a spin-off from space technology, a Wolter I type X-ray optics in combination with a prototype pn-CCD developed for ESA's XMM-Newton mission. As in other rare event searches, background suppression and a thorough shielding concept is essential to improve the sensitivity of the experiment to the best possible. In this context CAST offers the opportunity to study the background of pn-CCDs and its long term behavior in a terrestrial environment with possible implications for future space applications. We will present a systematic study of the detector background of the pn-CCD of CAST based on the data acquired since 2002 including preliminary results of our background simulations.Comment: 11 pages, 8 figures, to appear in Proc. SPIE 5898, UV, X-Ray, and Gamma-Ray Space Instrumentation for Astronomy XI

State space modelling and data analysis exercises in LISA Pathfinder

LISA Pathfinder is a mission planned by the European Space Agency to test the key technologies that will allow the detection of gravitational waves in space. The instrument on-board, the LISA Technology package, will undergo an exhaustive campaign of calibrations and noise characterisation campaigns in order to fully describe the noise model. Data analysis plays an important role in the mission and for that reason the data analysis team has been developing a toolbox which contains all the functionalities required during operations. In this contribution we give an overview of recent activities, focusing on the improvements in the modelling of the instrument and in the data analysis campaigns performed both with real and simulated data.Comment: Plenary talk presented at the 9th International LISA Symposium, 21-25 May 2012, Pari

The LISA Pathfinder Mission

LISA Pathfinder (formerly known as SMART-2) is an European Space Agency mission designed to pave the way for the joint ESA/NASA Laser Interferometer Space Antenna (LISA) mission by testing in flight the critical technologies required for space-borne gravitational wave detection; it will put two test masses in a near-perfect gravitational free-fall and control and measure their motion with unprecedented accuracy. This is achieved through technology comprising inertial sensors, high precision laser metrology, drag-free control, and an ultra precise micro-Newton propulsion system. LISA Pathfinder (LPF) essentially mimics one arm of spaceborne gravitational wave detectors by shrinking the million kilometre scale armlengths down to a few tens of centimetres, giving up the sensitivity to gravitational waves, but keeping the measurement technology. The scientific objective of the LISA Pathfinder mission consists then of the first in-flight test of low frequency gravitational wave detection metrology. In this paper I will give a brief overview of the mission, focusing on scientific and technical goals

Effects of maternal fructose intake on perinatal ER-Stress: A defective XBP1s nuclear translocation affects the ER-stress resolution

Endoplasmic reticulum (ER) homeostasis is crucial to appropriate cell functioning, and when disturbed, a safeguard system called unfolded protein response (UPR) is activated. Fructose consumption modifies ER homeostasis and has been related to metabolic syndrome. However, fructose sweetened beverages intake is allowed during gestation. Therefore, we investigate whether maternal fructose intake affects the ER status and induces UPR. Thus, administrating liquid fructose (10% w/v) to pregnant rats partially activated the ER-stress in maternal and fetal liver and placenta. In fact, a fructose-induced increase in the levels of pIRE1 (phosphorylated inositol requiring enzyme-1) and its downstream effector, X-box binding protein-1 spliced form (XBP1s), was observed. XBP1s is a key transcription factor, however, XBP1s nuclear translocation and the expression of its target genes were reduced in the liver of the carbohydrate-fed mothers, and specifically diminished in the fetal liver and placenta in the fructose-fed mothers. These XBP1s target genes belong to the ER-associated protein degradation (ERAD) system, used to buffer ER-stress and to restore ER-homeostasis. It is known that XBP1s needs to form a complex with diverse proteins to migrate into the nucleus. Since methylglyoxal (MGO) content, a precursor of advanced glycation endproducts (AGE), was augmented in the three tissues in the fructose-fed mothers and has been related to interfere with the functioning of many proteins, the role of MGO in XBP1s migration should not be discarded. In conclusion, maternal fructose intake produces ER-stress, but without XBP1s nuclear migration. Therefore, a complete activation of UPR that would resolve ER-stress is lacking. A state of fructose-induced oxidative stress is probably involved

ESA's Soil Moisture and Ocean Salinity mission : from science to operational applications

The Soil Moisture and Ocean Salinity (SMOS) mission, launched in November 2009, is the European Space Agency's (ESA) second Earth Explorer Opportunity mission. The scientific objectives of the SMOS mission directly respond to the need for global observations of soil moisture and ocean salinity, two key variables used in predictive hydrological, oceanographic and atmospheric models. SMOS observations also provide information on vegetation, in particular plant available water and water content in a canopy, drought index and flood risks, surface ocean winds in storms, freeze/thaw state and sea ice and its effect on ocean–atmosphere heat fluxes and dynamics affecting large-scale processes of the Earth's climate system. Significant progress has been made over the course of the now 6-year life time of the SMOS mission in improving the ESA provided level 1 brightness temperature and level 2 soil moisture and sea surface salinity data products. The main emphasis of this paper is to review the status of the mission and provide an overview and performance assessment of SMOS data products, in particular with a view towards operational applications, and using SMOS products in data assimilation. SMOS is in excellent technical condition with no limiting factors for operations beyond 2017. The instrument performance fulfils the requirements. The radio-frequency interference (RFI) contamination originates from man-made emitters on ground, operating in the protected L-band and adding signal to the natural radiation emitted by the Earth. RFI has been detected worldwide and has been significantly reduced in Europe and the Americas but remains a constraint in Asia and the Middle East. The mission's scientific objectives have been reached over land and are approaching the mission objectives over ocean. This review paper aims to provide an introduction and synthesis to the papers published in this RSE special issue on SMOS

From laboratory experiments to LISA Pathfinder: achieving LISA geodesic motion

This paper presents a quantitative assessment of the performance of the upcoming LISA Pathfinder geodesic explorer mission. The findings are based on the results of extensive ground testing and simulation campaigns using flight hardware, flight control and operations algorithms. The results show that, for the central experiment of measuring the stray differential acceleration between the LISA test masses, LISA Pathfinder will be able to verify the overall acceleration noise to within a factor 2 of the LISA requirement at 1 mHz and within a factor 6 at 0.1 mHz. We also discuss the key elements of the physical model of disturbances, coming from LISA Pathfinder and ground measurement that will guarantee the LISA performance