90 research outputs found

    Benefitting from the Grey Literature in Software Engineering Research

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    Researchers generally place the most trust in peer-reviewed, published information, such as journals and conference papers. By contrast, software engineering (SE) practitioners typically do not have the time, access or expertise to review and benefit from such publications. As a result, practitioners are more likely to turn to other sources of information that they trust, e.g., trade magazines, online blog-posts, survey results or technical reports, collectively referred to as Grey Literature (GL). Furthermore, practitioners also share their ideas and experiences as GL, which can serve as a valuable data source for research. While GL itself is not a new topic in SE, using, benefitting and synthesizing knowledge from the GL in SE is a contemporary topic in empirical SE research and we are seeing that researchers are increasingly benefitting from the knowledge available within GL. The goal of this chapter is to provide an overview to GL in SE, together with insights on how SE researchers can effectively use and benefit from the knowledge and evidence available in the vast amount of GL

    A Newly Identified Essential Complex, Dre2-Tah18, Controls Mitochondria Integrity and Cell Death after Oxidative Stress in Yeast

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    A mutated allele of the essential gene TAH18 was previously identified in our laboratory in a genetic screen for new proteins interacting with the DNA polymerase delta in yeast [1]. The present work shows that Tah18 plays a role in response to oxidative stress. After exposure to lethal doses of H2O2, GFP-Tah18 relocalizes to the mitochondria and controls mitochondria integrity and cell death. Dre2, an essential Fe/S cluster protein and homologue of human anti-apoptotic Ciapin1, was identified as a molecular partner of Tah18 in the absence of stress. Moreover, Ciapin1 is able to replace yeast Dre2 in vivo and physically interacts with Tah18. Our results are in favour of an oxidative stress-induced cell death in yeast that involves mitochondria and is controlled by the newly identified Dre2-Tah18 complex

    Principles of Hand Fracture Management

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    The hand is essential in humans for physical manipulation of their surrounding environment. Allowing the ability to grasp, and differentiated from other animals by an opposing thumb, the main functions include both fine and gross motor skills as well as being a key tool for sensing and understanding the immediate surroundings of their owner

    Webometrics benefitting from web mining? An investigation of methods and applications of two research fields

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    Webometrics and web mining are two fields where research is focused on quantitative analyses of the web. This literature review outlines definitions of the fields, and then focuses on their methods and applications. It also discusses the potential of closer contact and collaboration between them. A key difference between the fields is that webometrics has focused on exploratory studies, whereas web mining has been dominated by studies focusing on development of methods and algorithms. Differences in type of data can also be seen, with webometrics more focused on analyses of the structure of the web and web mining more focused on web content and usage, even though both fields have been embracing the possibilities of user generated content. It is concluded that research problems where big data is needed can benefit from collaboration between webometricians, with their tradition of exploratory studies, and web miners, with their tradition of developing methods and algorithms

    Harmful Elements in Estuarine and Coastal Systems

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    Estuaries and coastal zones are dynamic transitional systems which provide many economic and ecological benefits to humans, but also are an ideal habitat for other organisms as well. These areas are becoming contaminated by various anthropogenic activities due to a quick economic growth and urbanization. This chapter explores the sources, chemical speciation, sediment accumulation and removal mechanisms of the harmful elements in estuarine and coastal seawaters. It also describes the effects of toxic elements on aquatic flora and fauna. Finally, the toxic element pollution of the Venice Lagoon, a transitional water body located in the northeastern part of Italy, is discussed as a case study, by presenting the procedures adopted to measure the extent of the pollution, the impacts on organisms and the restoration activities

    Temporal and spatial distribution of diatoms in the surface sediment of the central part of the Venice lagoon

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    The aim of this paper was to improve the knowledge of the primary producers living in the Venice Lagoon by studying the composition and the distribution of the benthic diatom communities populating subtidal surface sediments. The upper 5 mm of sediment from four areas distributed between the Malamocco inlet and the mainland north of Venice were collected and analysed. Sampling was carried out monthly for one year (199899). Species composition, cell abundance and carbon content were determined by light microscopy after separation of cells from the sediment particles using hydrogen peroxide. A total of 147 taxa were identified, mostly pennate diatoms (Bacillariales) belonging to the genera Amphora, Cocconcis, Navicula, Nitzschia and Pleurosigma. Cell abundance ranged from 0.7 x 10(6) Cells cm(-3), near the Malamocco inlet (Station A), to 10.4 x 10(6) cells cm(-3) near the mainland (Station Q. Diatom carbon content was between 28 and 380 mug cm(-3). Seasonal trends were slight, except at Stations D and C where the lowest abundance was found in October-November and the highest one in summer. Significant relationships between benthic diatoms and macrophyte biomass, sediment grain size, underwater light transmission, sediment fluxes and the salinity gradient were found
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