2,461 research outputs found

    Gest?o de recursos humanos na administra??o p?blica : uma experi?ncia de est?gio na C?mara Municipal de Melga?o

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    Mestrado em Gest?o das Organiza??es : Ramo de Gest?o de Empresas (parceria com a APNOR) na Escola Superior de Tecnologia e Gest?o do Instituto Polit?cnico de Viana do CasteloCom a globaliza??o do mundo atual, tem-se discutido cada vez mais a Gest?o de Recursos Humanos nas organiza??es, devido aos novos desafios e oportunidades de atua??o. Dentro deste conceito, que ? a GRH, devem ser definidas todas as pr?ticas e estrat?gias de atua??o que t?m como miss?o atingir determinados objetivos e promover o desempenho organizacional. Tendo como base este conceito, o presente trabalho consiste num relat?rio final de est?gio, que integra o 2? ano do Mestrado em Gest?o das Organiza??es, realizado no Instituto Polit?cnico de Viana do Castelo, com o objetivo geral de compreender o impacto da atua??o do departamento de Recursos Humanos no Munic?pio de Melga?o. Neste sentido, o est?gio curricular foi desenvolvido no edif?cio da C?mara Municipal de Melga?o, nomeadamente no gabinete do Departamento dos Recursos Humanos. Este contanto direto com o contexto laboral, permitiu uma forma??o mais pr?tica nas diversas tarefas desenvolvidas, num departamento t?o abrangente como ? o caso dos recursos humanos. Com vista nos objetivos estipulados para a realiza??o do est?gio curricular, al?m da disponibilidade de documentos internos e de toda a informa??o recolhida e analisada na revis?o bibliogr?fica descrita abaixo, foi desenvolvida uma entrevista n?o estruturada aos colaboradores do Munic?pio, bem como criadas propostas de a??es de responsabilidade social com o objetivo de melhorar o esp?rito de equipa e a satisfa??o dos colaboradores. Conclui-se que, de uma forma geral, o Departamento dos Recursos Humanos tem investido muito na forma??o e corre??o de a??es, com vista a melhorar os seus resultados de atua??o. No entanto, no final deste relat?rio ser?o enumeradas algumas recomenda??es no sentido de refor?ar e melhorar todas essas a??es j? implementadas.Con la globalizaci?n del mundo actual, la gesti?n de recursos humanos se ha debatido cada vez m?s en las organizaciones, a medida que surgen nuevos desaf?os y oportunidades para el rendimiento y el crecimiento. Dentro de este concepto, que es la Gesti?n de Recursos Humanos, deben definirse todas las pr?cticas y estrategias de acci?n que tienen la misi?n de lograr ciertos objetivos y promover el desempe?o organizacional. En base a este concepto, el presente trabajo consiste en un informe final de pr?cticas, que integra el 2? a?o del M?ster en Gesti?n de Organizaciones, realizado en el Instituto Polit?cnico de Viana do Castelo, con el objetivo general de comprender el impacto del desempe?o del departamento de Recursos Humanos en el Municipio de Melga?o. En este sentido, la pr?ctica curricular se realiz? en el edificio del Ayuntamiento de Melga?o, concretamente en la oficina del Departamento de Recursos Humanos. Este contacto directo con el contexto laboral, permiti? una formaci?n m?s pr?ctica en las diversas tareas desarrolladas, en un departamento tan completo como es el caso de los recursos humanos. En vista de los objetivos estipulados para la realizaci?n de la pr?ctica curricular, adem?s de la disponibilidad de documentos internos y toda la informaci?n recopilada y analizada en la revisi?n bibliogr?fica descrita a continuaci?n, se desarroll? una entrevista no estructurada con los empleados de la Municipalidad, as? como propuestas de acci?n creadas. responsabilidad social para mejorar el esp?ritu de equipo y la satisfacci?n de los empleados. Se concluye que, en general, el Departamento de Recursos Humanos ha invertido mucho en la formaci?n y correcci?n de acciones, con el fin de mejorar sus resultados de desempe?o. Sin embargo, al final de este informe, se enumerar?n algunas recomendaciones para reforzar y mejorar todas estas acciones ya implementadas.With the globalization of the current world, Human Resources Management has been increasingly discussed in organizations, as new challenges and opportunities for performance and growth have arisen. Within this concept, which is the Human Resource Management, all the practices and strategies of action that have the mission of achieving certain objectives and promoting organizational performance must be defined. Based on this concept, the present work consists of a final internship report, which integrates the 2nd year of the Master's Degree in Management of Organizations, held at the Polytechnic Institute of Viana do Castelo, with the general objective of understanding the impact of the performance of the department of Human Resources in the Municipality of Melga?o. In this sense, the curricular internship was carried out in the Melga?o City Hall building, namely in the Human Resources Department office. This direct contact with the work context, allowed a more practical training in the various tasks developed, in a department as comprehensive as is the case of human resources. In view of the objectives stipulated for the completion of the curricular internship, in addition to the availability of internal documents and all the information collected and analyzed in the bibliographic review described below, an unstructured interview was developed with the Municipality's employees, as well as, created action proposals. social responsibility in order to improve team spirit and employee satisfaction. It is concluded that, in general, the Human Resources Department has invested a lot in the formation and correction of actions, in order to improve its performance results. However, at the end of this report, some recommendations will be listed in order to reinforce and improve all these actions already implemented

    Carreadores lip?dicos nanoestruturados contendo benznidazol como estrat?gia para aumentar a efic?cia no tratamento da doen?a de Chagas

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    ?rea de concentra??o: Pesquisa e Desenvolvimento de Insumos, F?rmacos e Medicamentos.A doen?a de Chagas (DC) ? uma antropozoonose causada pelo protozo?rio Trypanosoma cruzi que atinge milh?es de pessoas principalmente na Am?rica Latina e cujo tratamento permanece insatisfat?rio. O benznidazol (BZN) ? considerado a primeira escolha para o tratamento devido a sua maior tolerabilidade pelos pacientes. Entretanto, este f?rmaco apresenta baixa solubilidade aquosa, absor??o oral irregular, farmacocin?tica desfavor?vel, al?m de ocasionar v?rios efeitos adversos. A incorpora??o de f?rmacos com estas caracter?sticas em sistemas lip?dicos nanoestruturados representa uma alternativa para melhorar estes fatores limitantes. Diante disso, o objetivo deste estudo foi desenvolver, caracterizar e avaliar a efic?cia tripanocida in vitro de carreadores lip?dicos nanoestruturados (CLN) contendo BZN. O desenvolvimento da formula??o avaliou a influ?ncia do l?pide l?quido, da composi??o do sistema tensoativo, da concentra??o de l?pides e da concentra??o de BZN no tamanho, potencial zeta (PZ) e incorpora??o do f?rmaco no nanossistema. A formula??o otimizada tamb?m foi caracterizada por espectroscopia no infravermelho, difra??o de raios-X, calorimetria explorat?ria diferencial, termogravimetria e microscopia eletr?nica de varredura. Avaliou-se tamb?m a estabilidade preliminar, o potencial hemol?tico, toxicidade em c?lulas L929 e atividade tripanocida em formas epimastigotas do T. cruzi. O CLN-BZN desenvolvido apresentou morfologia esf?rica, di?metro m?dio compat?vel ? administra??o oral (110 ? 3 nm), PZ negativo e preditivo de estabilidade (-18,0 ? 2,6 mV), al?m de alto teor de encapsula??o de BZN (82,6 ? 2,1%). A atividade tripanocida do CLN-BZN foi similar ao f?rmaco livre at? a concentra??o de 31 ?g/mL. Contudo a formula??o apresentou baixo potencial hemol?tico e menor toxicidade em c?lulas L929 em compara??o ao BZN livre. Estes resultados sugerem que a formula??o desenvolvida apresenta caracter?sticas adequadas para a administra??o oral, sendo assim uma alternativa promissora para o tratamento da DC.Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior (CAPES)Disserta??o (Mestrado) ? Programa de P?s-gradua??o em Ci?ncias Farmac?uticas, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 2019.Chagas disease (CD) is an anthropozoonosis caused by the protozoan Trypanosoma cruzi, which affects millions of people mainly in Latin America with unsatisfactory treatment. Benznidazole (BZN) is related as first choice for treatment since presents greater tolerability by patients. However, this drug shows low aqueous solubility, irregular oral absorption, unfavorable pharmacokinetics, resulting several adverse effects. In that way, incorporation of drugs with these characteristics into nanostructured lipid systems represents an alternative to improve these limiting factors. In this context, the aim of this study is based on development, characterization and evaluation of in vitro trypanocidal efficacy of nanostructured lipid carriers (NLC) loaded with BZN. The influence of liquid lipid, surfactant system composition, lipid concentration and BZN concentration on size, zeta potential (ZP) and incorporation of the drug in the nanosystem were evaluated for each formulation. The optimized formulation was also characterized by infrared spectroscopy, X-ray diffraction, differential scanning calorimetry, thermogravimetry and scanning electron microscopy. Preliminary stability, hemolytic potential, toxicity in L929 cells and trypanocidal activity in T. cruzi epimastigote forms were also carried out. NLC-BZN showed spherical morphology, mean diameter compatible with oral administration (110 ? 3 nm), Zp negative and predictive of stability (-18,0 ? 2,6 mV), and high encapsulation efficiency of BZN (82,6 ? 2,1%), which was proved by the other characterizations. The optimized formulation showed low hemolytic potential and lower toxicity in L929 cells compared to free BZN, and trypanocidal activity was similar to the free drug up to the concentration of 31 ?g/mL. These results suggest that the optimized formulation presents highlight characteristics for oral administration, representing a promising alternative for the treatment of DC

    Optimization of reinforced concrete polygonal sections under biaxial bending with axial force.

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    Concrete is the world?s most utilized material for production of the structural elements employed in civil construction. Due to its low tensile strength and brittle nature it is reinforced with steel bars forming the reinforced concrete (RC structure). Linear elements of reinforced concrete are commonly employed in multi-story buildings, bridges, industrial sheds, among others. In this study an optimization algorithm is presented to define the amount of steel and its location within a concrete polygonal section subjected to biaxial bending with axial force, so that the amount of steel would be the minimum needed to resist the soliciting forces. Therefore, the project variables are: location, diameter and number of steel bars to be distributed within the concrete polygonal section. The sequential linear programming method is used to determine the optimized section. In this method, the non-linear problem of determining the resistance forces of the section in relation to the project variables is approximated by a sequence of linear problems, which would have its optimal point defined for each step using the Simplex method. Formulation validation is done through results of examples found in literature, and also by means of analytical solutions of simple problems, such as rectangular sections under axial force and moment in only one axis of symmetry. The results show the efficiency of the algorithm implemented in the optimized determination of the quantity and position of the bars of a given diameter in the polygonal section of reinforced concrete under biaxial bending with axial force

    [El libro de la vida]

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    Copia digital : Junta de Castilla y León. Consejería de Cultura y Turismo, 201

    SEEDLINGS PRODUCTION OF UMBUZEIRO ( Spondias tuberosa Arruda C\ue2mara) IN DIFFERENT SUBSTRATES AND SIZE OF BAGS

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    A esp\ue9cie Spondias tuberosa Arr. Cam. (umbuzeiro) destaca-se como uma das esp\ue9cies arb\uf3reas de maior potencial do semi\ue1rido brasileiro. Apesar de sua relevante import\ue2ncia socioecon\uf4mica e ambiental, h\ue1 falta de estudos voltados para o estabelecimento de um modelo de produ\ue7\ue3o de mudas da esp\ue9cie. O objetivo desse trabalho foi avaliar a produ\ue7\ue3o de mudas de Spondias tuberosa utilizando diferentes substratos e tamanho de recipientes. O experimento foi conduzido no viveiro do Laborat\uf3rio de Ecologia Vegetal (LEV) do Centro de Ci\ueancias Agr\ue1rias (CCA) da Universidade Federal da Para\uedba (UFPB), Areia - PB. O delineamento experimental usado foi em blocos casualizados em esquema fatorial 2 x 7 e parcelas subdivididas, sendo que os recipientes representaram as parcelas e os substratos as subparcelas. Foram utilizados substratos formulados a partir da mistura de terra de subsolo (37,5-100%), areia lavada (12,5- 25%) e esterco bovino curtido (10-50%). Os recipientes utilizados foram sacos de polietileno preto com volumes de 1900 cm3 (15 x 27 cm) e 5000 cm3 (25 x 26 cm). Para a obten\ue7\ue3o das pl\ue2ntulas, sementes de Spondias tuberosa foram semeadas em sementeira de alvenaria at\ue9 a repicagem (90 dias ap\uf3s o semeio). Aos 78 dias, ap\uf3s a repicagem, as mudas foram avaliadas quanto \ue0 altura, di\ue2metro do colo, rela\ue7\ue3o altura/ di\ue2metro do colo, di\ue2metro do xilop\uf3dio, comprimento de raiz, massa seca da parte a\ue9rea e raiz. Os dados obtidos foram submetidos \ue0 an\ue1lise de vari\ue2ncia e ao teste F, sendo as m\ue9dias comparadas pelo teste de Tukey ao n\uedvel de 5% de probabilidade, utilizando o software SISVAR\uae. Os substratos com esterco bovino curtido proporcionaram os maiores valores em altura e comprimento de raiz. Para a produ\ue7\ue3o de mudas de Spondias tuberosa, \ue9 recomendado o substrato contendo terra de subsolo (45%) + Areia (15%) + Esterco bovino (40%).The species Spondias tuberosa Arr. Cam. (umbuzeiro) stands out as one of the tree species with the greatest potential of the Brazilian semiarid. Even though it\u2019s significant socioeconomic and environmental importance, there is a lack of studies aimed at establishing a seedlings production model of this kind of plant. The purpose of this study was to evaluate the production of seedlings Spondias tuberosa using different substrates and size of bags. The experiment was conducted in the nursery of the Plant Ecology Laboratory (LEV) from the Agrarian Sciences Center (CCA) of the Federal University of Paraiba (UFPB), Areia/ PB. The experimental design was a randomized block in factorial 2 x 7 and subdivided blocks containersplots and subplots substrates. It were used substrates formulated from the starting mixture of subsoil land (37.5-100%), sand (12.5-25%) and tanned cattle manure (10-50%). The containers used were black polyethylene bags with a volume of 1900 cm3 (15 x 27 cm) and 5000 cm3 (25 x 26 cm). To obtain seedlings of Spondias tuberosa seeds were sown in seed masonry until the transplant (90 days after sowing). At 78 days after transplanting the seedlings were evaluated for height, root collar diameter, relationship shoot/root collar diameter, xylopodium diameter, root length, dry weigh of shoot and root. The datas were subjected to analysis of variance and F test, measured and compared by Tukey test at 5% probability, using the software SISVAR\uae. The substrates with cattle manure provided higher values for height and root length. For the seedlings production of Spondias tuberosa, is recommended substrate subsoil land (45%) + sand (15%) + cattle manure (40%)

    SALT STRESS ON THE PHYSIOLOGICAL QUALITY OF Cryptostegia madagascariensis Bojer ex Decne. SEEDS

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    A esp\ue9cie Cryptostegia madagascariensis Bojer ex Decne. foi introduzida no Brasil com fins ornamentais, mas, atualmente, \ue9 uma invasora do bioma Caatinga. Apesar de sua elevada capacidade de ocupa\ue7\ue3o de \ue1reas alteradas do referido bioma, h\ue1 car\ueancia de informa\ue7\uf5es sobre esta esp\ue9cie, particularmente em rela\ue7\ue3o \ue0 capacidade de suas sementes germinarem em condi\ue7\uf5es adversas. O objetivo deste trabalho foi avaliar a germina\ue7\ue3o de sementes e o crescimento inicial de pl\ue2ntulas de Cryptostegia madagascariensis em fun\ue7\ue3o da salinidade em diferentes temperaturas. O experimento foi realizado seguindo um delineamento inteiramente casualizado, com os tratamentos distribu\ueddos em esquema fatorial 6 x 3, sendo seis n\uedveis de salinidade promovidos pelo cloreto de s\uf3dio (NaCl): 0,0 (controle); 2,0; 4,0; 6,0; 8,0 e 10,0 dS m-1; e tr\ueas temperaturas: 25 e 30\ub0C constantes e alternada de 20-35\ub0C. A qualidade fisiol\uf3gica das sementes foi avaliada pelas seguintes vari\ue1veis: germina\ue7\ue3o, primeira contagem e \uedndice de velocidade de germina\ue7\ue3o, comprimento e massa seca de ra\uedzes e do hipoc\uf3tilo. Os resultados obtidos indicam que h\ue1 elevada probabilidade de germina\ue7\ue3o de sementes de Cryptostegia madagascariensis submetidas a estresse salino em temperatura constante de 30\ub0C e alternada de 20-35\ub0C, o que potencializa o seu car\ue1ter invasor.The Cryptostegia madagascariensis Bojer ex Decne. species was introduced in Brazil with ornamental purposes, but currently, it is invasive in the Caatinga biome. Despite its high level of occupancy of altered areas of Caatinga, there is lack of information about this species, particularly in relation to the capacity of its seeds to germinate in adverse conditions. The objective of this study was to evaluate seed germination and the initial seedling growth of Cryptostegia madagascariensis in function of salinity at different temperatures. The experiment was conducted following a completely randomized design, with treatments arranged in a 6 x 3 factorial design with six salinity levels promoted by sodium chloride (NaCl): 0.0 (control); 2.0; 4.0; 6.0; 8.0 and 10.0 dS m-1 and three temperatures: 25 and 30\ub0C constant and alternating 20-35\ub0C. The physiological quality of seeds was evaluated using the following variables: germination, first count and the speed of germination index, length and dry weight of roots and hypocotyl. The results indicate that there is high probability of seed germination of Cryptostegia madagascariensis subjected to salt stress at constant temperature of 30\ub0C and alternating 20-35\ub0C, which enhances its invasive character

    First report of venereal and vertical transmission of canine leishmaniosis from naturally infected dogs in Germany

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    <p>Abstract</p> <p>Background</p> <p>Canine leishmaniosis (CanL) is a zoonotic disease caused by <it>Leishmania (L.) infantum</it>. It is endemic to several tropical and subtropical countries but also to the Mediterranean region. It is transmitted by phlebotomine sandflies but occasional non-vector transmissions have been reported, including vertical and horizontal transmission.</p> <p>Findings</p> <p>The authors report a case of CanL in a female boxer dog from Dusseldorf, Germany, that had never been in an endemic region. A serum sample from the bitch was tested positive for antibodies against <it>Leishmania </it>(IFAT 1:2,000, ELISA 72). The bitch had whelped three litters, and one puppy from the third litter was also found to be seropositive for <it>Leishmania </it>antibodies (IFAT 1:4,000, ELISA 78).</p> <p>Conclusions</p> <p>Up to now, despite intensive searching, the occurrence of sandflies could not be proved in the bitch's region of origin. Thus, vertical and horizontal transmission are to be discussed as possible ways of infection. This may be the first report of venereal and vertical transmission of <it>L. infantum </it>in naturally infected dogs in Germany.</p

    STUDY OF FIRE BEHAVIOR ON A PART OF SEMIDECIDUOUS SEASONAL FOREST IN VI\uc7OSA, MINAS GERAIS

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    O objetivo do presente estudo foi avaliar o comportamento do fogo em um trecho de Floresta Estacional Semidec\ueddua, usando as vari\ue1veis: intensidade do fogo, tempo de queima, material combust\uedvel, poder calor\uedfico e calor liberado por \ue1rea. Foram instaladas 10 parcelas de 5 x 5 m interdistantes em 1 m, perfazendo um total de 250 m2, em um fragmento denominado \u201cReserva da Biologia\u201d, pertencente \ue0 Universidade Federal de Vi\ue7osa, Minas Gerais, (20\uba35\u2019-28\uba50\u2019S e 42\uba45\u2019-43\uba00\u2019W) onde foi realizada a queima controlada utilizando a t\ue9cnica do fogo a favor do vento, obedecendo ao sentido do aclive. Determinouse a quantidade de mat\ue9ria seca, velocidade de propaga\ue7\ue3o do fogo, intensidade, calor liberado e poder calor\uedfico. O tempo de dura\ue7\ue3o da queima variou entre as parcelas de 3\u201930\u201d a 9\u201918\u201d. A velocidade do vento, temperatura e umidade relativa do ar no dia da queima permaneceram constantes em todas as parcelas, apresentando valores de 3,5 m s-1 Norte, 20\ubaC e 79%, respectivamente. Os par\ue2metros do comportamento do fogo variaram entre as parcelas em: 0,32 a 1,10 kg m-2 para material combust\uedvel, 11,94 a 75,79 Kcal s-1 m-1 para a intensidade de queima e 1111 a 3789 Kcal m-2 para o calor liberado por \ue1rea. Os valores m\ue9dios para velocidade de propaga\ue7\ue3o e poder calor\uedfico foram 0,017 m s-1 e 4411 Kcal Kg-1, respectivamente. As condi\ue7\uf5es clim\ue1ticas de Vi\ue7osa em 2005 foram at\uedpicas em rela\ue7\ue3o aos outros anos, n\ue3o apresentando nenhum m\ueas seco. Esta condi\ue7\ue3o interferiu nos par\ue2metros do comportamento do fogo, fazendo com que a queima fosse classificada como de baixa intensidade.The purpose of this study was to evaluate the fire behavior on a part of Semideciduous Seasonal Forest, using the variables: fire intensity, burning time, fuel, heat content and heat released. Ten plots of 5 by 5 meters were used , totalizing 250 m2, and the distance between each plot was 1 meter in a place named \u201cReserva da Biologia\u201d property of Universidade Federal de Vi\ue7osa, Minas Gerais, (20\uba35\u2019-28\uba50\u2019S e 42\uba45\u2019-43\uba00\u2019W) . In this place a control burning was performed using strip headfire technique, obeying the slope direction. The amount of local dry matter, fire propagation velocity, intensity, heat released and heat content were measured. The time duration of the burning ranged between plots of 3\u201930 \u201cto 9\u201918\u201d. Wind velocity, temperature, relative humidity were constant in all plots, with values 3, 5 m s-1 North, 20\uba C and 79% respectively. The values found for fire behavior variables ranged between plots: from 0, 32 to 1, and 10 Kg m-2 for fuel, from 11, 94 to 75,79 Kcals-1m-1 for burning intensity and from 1111 to 3789 Kcal m-2 for heat released. The average values for rate of spread and heat released were 0,017 m s-1 and 4411 Kcal Kg-1, respectively. In the year 2005, the weather conditions were atypical comparing to another years in Vi\ue7osa, witch in every month occurs a certain amount of rain. This fact had interference in the fire behavior parameters, for that reason the burning were classified as low intensity
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