Engineering tests of the C-141 telescope

Data on image quality, chopper performance, and the closed-loop operation of the 91 cm telescope of the Kuiper Airborne Observatory which were obtained in September 1977 are presented

Superfluid phases of the three-species fermion gas

We discuss the zero temperature phase diagram of a dilute gas with three fermionic species. We make use of solvable limits to conjecture the behavior of the system in the "unitary" regions. The physics of the Thomas-Efimov effect plays a role in these considerations. We find a rich phase diagram with superfluid, gapless superfluid and inhomogeneous phases with different symmetry breaking patterns. We then discuss one particular possible experimental implementation in a system of ^6Li atoms and the possible phases arising in this system as an external magnetic field is varied across three overlaping Feshbach resonances. We also suggest how to experimentally distinguish the different phases.Comment: 4 pages, 1 figure, typos corrected and references adde

Transmission electron microscopy investigation of segregation and critical floating-layer content of indium for island formation in InGaAs

We have investigated InGaAs layers grown by molecular-beam epitaxy on GaAs(001) by transmission electron microscopy (TEM) and photoluminescence spectroscopy. InGaAs layers with In-concentrations of 16, 25 and 28 % and respective thicknesses of 20, 22 and 23 monolayers were deposited at 535 C. The parameters were chosen to grow layers slightly above and below the transition between the two- and three-dimensional growth mode. In-concentration profiles were obtained from high-resolution TEM images by composition evaluation by lattice fringe analysis. The measured profiles can be well described applying the segregation model of Muraki et al. [Appl. Phys. Lett. 61 (1992) 557]. Calculated photoluminescence peak positions on the basis of the measured concentration profiles are in good agreement with the experimental ones. Evaluating experimental In-concentration profiles it is found that the transition from the two-dimensional to the three-dimensional growth mode occurs if the indium content in the In-floating layer exceeds 1.1+/-0.2 monolayers. The measured exponential decrease of the In-concentration within the cap layer on top of the islands reveals that the In-floating layer is not consumed during island formation. The segregation efficiency above the islands is increased compared to the quantum wells which is explained tentatively by strain-dependent lattice-site selection of In. In addition, In0.25Ga0.75As quantum wells were grown at different temperatures between 500 oC and 550 oC. The evaluation of concentration profiles shows that the segregation efficiency increases from R=0.65 to R=0.83.Comment: 16 pages, 6 figures, 1 table, sbmitted in Phys. Rev.

Out-of-sequence faulting of the Jwalamukhi Thrust, India

The southernmost thrust of the Himalayan orogenic wedge that separates the foreland from the orogen, the Main Frontal Thrust, is thought to accommodate most of the ongoing crustal shortening in the Sub-Himalaya. Steepened longitudinal river profile segments, terrace offsets, and back-tilted fluvial terraces within the Kangra reentrant of the NW Sub-Himalaya suggest Holocene activity of the Jwalamukhi Thrust (JMT) and other thrust faults that may be associated with strain partitioning along the toe of the Himalayan wedge. To assess the shortening accommodated by the JMT, we combine morphometric terrain analyses with in situ 10Be-based surface-exposure dating of the deformed terraces. Incision into upper Pleistocene sediments within the Kangra Basin created two late Pleistocene terrace levels (T1 and T2). Subsequent early Holocene aggradation shortly before ~10 ka was followed by episodic reincision, which created four cut-and-fill terrace levels, the oldest of which (T3) was formed at 10.1 ± 0.9 ka. A vertical offset of 44 ± 5 m of terrace T3 across the JMT indicates a shortening rate of 5.6 ± 0.8 to 7.5 ± 1.1 mm a−1 over the last ~10 ka. This result suggests that thrusting along the JMT accommodates 40–60% of the total Sub-Himalayan shortening in the Kangra reentrant over the Holocene. We speculate that this out-of-sequence shortening may have been triggered or at least enhanced by late Pleistocene and Holocene erosion of sediments from the Kangra Basin

Об анатомическом строении членистостебельного растения Annulina Neuburgiana Radczenko

The purpose was to compare two approaches for the acquisition and analysis of dynamic-contrast-enhanced MRI data with respect to differences in the modelling of the arterial input-function (AIF), the dependency of the model parameters on physiological parameters and their numerical stability. Eight hundred tissue concentration curves were simulated for different combinations of perfusion, permeability, interstitial volume and plasma volume based on two measured AIFs and analysed according to the two commonly used approaches. The transfer constants (Approach 1) K (trans) and (Approach 2) k (ep) were correlated with all tissue parameters. K (trans) showed a stronger dependency on perfusion, and k (ep) on permeability. The volume parameters (Approach 1) v (e) and (Approach 2) A were mainly influenced by the interstitial and plasma volume. Both approaches allow only rough characterisation of tissue microcirculation and microvasculature. Approach 2 seems to be somewhat more robust than 1, mainly due to the different methods of CA administration

Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization.

BACKGROUND: The recent West African Ebola epidemic led to accelerated efforts to test Ebola vaccine candidates. As part of the World Health Organisation-led VSV Ebola Consortium (VEBCON), we performed a phase I clinical trial investigating rVSV-ZEBOV (a recombinant vesicular stomatitis virus-vectored Ebola vaccine), which has recently demonstrated protection from Ebola virus disease (EVD) in phase III clinical trials and is currently in advanced stages of licensing. So far, correlates of immune protection are incompletely understood and the role of cell-mediated immune responses has not been comprehensively investigated to date. METHODS: We recruited 30 healthy subjects aged 18-55 into an open-label, dose-escalation phase I trial testing three doses of rVSV-ZEBOV (3×105 plaque-forming units (PFU), 3×106 PFU, 2×107 PFU) (ClinicalTrials.gov; NCT02283099). Main study objectives were safety and immunogenicity, while exploratory objectives included lymphocyte dynamics, cell-mediated immunity and cytokine networks, which were assessed using flow cytometry, ELISpot and LUMINEX assay. FINDINGS: Immunization with rVSV-ZEBOV was well tolerated without serious vaccine-related adverse events. Ebola virus-specific neutralizing antibodies were induced in nearly all individuals. Additionally, vaccinees, particularly within the highest dose cohort, generated Ebola glycoprotein (GP)-specific T cells and initiated a cascade of signaling molecules following stimulation of peripheral blood mononuclear cells with Ebola GP peptides. INTERPRETATION: In addition to a benign safety and robust humoral immunogenicity profile, subjects immunized with 2×107 PFU elicited higher cellular immune responses and stronger interlocked cytokine networks compared to lower dose groups. To our knowledge these data represent the first detailed cell-mediated immuneprofile of a clinical trial testing rVSV-ZEBOV, which is of particular interest in light of its potential upcoming licensure as the first Ebola vaccine. VEBCON trial Hamburg, Germany (NCT02283099)