Activities of the European topic centre on soils: the Spanish information system on soils

3 pages, 9 references.-- Forma parte del capítulo Data Availability.-- Trabajo presentado al International Workshop celebrado del 9-11 de octubre 1999, en Alghero, Italia.Within the general activities of the ETC on soils one of the tasks is the development of the Spanish Information System on Soils. This activity is being developed under the agreement between the Spanish Ministry of Environment (MIMAM) and the Spanish High Council for Research (CSIC). This presentation focuses on the development of a database on soil hydraulic properties within the framework of the mentioned agreement MIMAM-CSIC. The database try to compile all existing data of hydraulic properties of the spanish soils. For the development of such a database we have taken into account the existing database of hydraulic properties of european soils (HYPRES) in which the IRNAS (CSIC) of Seville was a contributor. The spanish database on soil hydraulic properties includes detailed references of other soil properties, and the temporal variability of hydraulic properties due to the different soil use and management. This database can be an useful tool in the study of desertification processes, erosion and transport of contaminant.Peer reviewe

Diseño y control de filtros activos mediante simulación HIL

La implementación de los filtros activos es una de las soluciones más eficientes a la problemática que plantea el creciente uso de cargas no lineales en la red eléctrica y la proliferación de cargas distribuidas provenientes de energías renovables conectadas a la misma. El diseño de un filtro activo y del algoritmo para su control pueden realizarse mediante la simulación “Hardware in the loop” (HIL) en tiempo real. Estas simulaciones sirven de interfaz entre el modelo matemático de todos los elementos dinámicos relacionados con el sistema eléctrico bajo control (simulación de la planta) y el sistema integrado bajo prueba. En este trabajo se ha desarrollado la simulación en la máquina virtual de Typhoon HIL, tanto del modelo del filtro activo como de su algoritmo de control. Tras la comprobación de los modelos se ha implementado el algoritmo en una tarjeta de procesamiento digital (DSP). Para la elaboración del código de programación necesario en este sistema de control de prueba se incorporan las herramientas Simulink de Matlab y Code Composer Studio (CCS). Los resultados han sido satisfactorios en general y ofrecen la posibilidad de la implementación física del sistema propuesto con un coste reducido.Active Power Filter implementation is one of the most efficient solutions for problems which raises non-linear loads in the electric net and proliferation of the distributed charges which are coming from the connection of renewable energy sources. The active filter design and its control algorithm can do with the real time simulation “Hardware in the loop” (HIL). These simulations work as interface between the mathematician model of all dynamic elements, which relate to the under control electric system, and the integrated system which is under test. In this project, the simulation in the virtual machine of Typhoon HIL has been developed, including the filter active model and its control algorithm. After checking the model, the algorithm has been implanted in a digital signal processor card. To write the necessary programming code in this embedded system under test, Simulink of Matlab and Code Composer Studio tools are used. In general, results have been satisfactory, so the designed model give us the chance of implementing physically the system with a reduced price

Global mRNA expression analysis in myosin II deficient strains of Saccharomyces cerevisiae reveals an impairment of cell integrity functions

<p>Abstract</p> <p>Background</p> <p>The <it>Saccharomyces cerevisiae MYO1 </it>gene encodes the myosin II heavy chain (Myo1p), a protein required for normal cytokinesis in budding yeast. Myo1p deficiency in yeast (<it>myo1Δ</it>) causes a cell separation defect characterized by the formation of attached cells, yet it also causes abnormal budding patterns, formation of enlarged and elongated cells, increased osmotic sensitivity, delocalized chitin deposition, increased chitin synthesis, and hypersensitivity to the chitin synthase III inhibitor Nikkomycin Z. To determine how differential expression of genes is related to these diverse cell wall phenotypes, we analyzed the global mRNA expression profile of <it>myo1Δ </it>strains.</p> <p>Results</p> <p>Global mRNA expression profiles of <it>myo1Δ </it>strains and their corresponding wild type controls were obtained by hybridization to yeast oligonucleotide microarrays. Results for selected genes were confirmed by real time RT-PCR. A total of 547 differentially expressed genes (p ≤ 0.01) were identified with 263 up regulated and 284 down regulated genes in the <it>myo1Δ </it>strains. Gene set enrichment analysis revealed the significant over-representation of genes in the protein biosynthesis and stress response categories. The <it>SLT2/MPK1 </it>gene was up regulated in the microarray, and a <it>myo1Δslt2Δ </it>double mutant was non-viable. Overexpression of ribosomal protein genes <it>RPL30 </it>and <it>RPS31 </it>suppressed the hypersensitivity to Nikkomycin Z and increased the levels of phosphorylated Slt2p in <it>myo1Δ </it>strains. Increased levels of phosphorylated Slt2p were also observed in wild type strains under these conditions.</p> <p>Conclusion</p> <p>Following this analysis of global mRNA expression in yeast <it>myo1Δ </it>strains, we conclude that 547 genes were differentially regulated in <it>myo1Δ </it>strains and that the stress response and protein biosynthesis gene categories were coordinately regulated in this mutant. The <it>SLT2/MPK1 </it>gene was confirmed to be essential for <it>myo1Δ </it>strain viability, supporting that the up regulated stress response genes are regulated by the <it>PKC1 </it>cell integrity pathway. Suppression of Nikkomycin Z hypersensitivity together with Slt2p phosphorylation was caused by the overexpression of ribosomal protein genes <it>RPL30 </it>and <it>RPS31</it>. These ribosomal protein mRNAs were down regulated in the <it>myo1Δ </it>arrays, suggesting that down regulation of ribosomal biogenesis may affect cell integrity in <it>myo1Δ </it>strains.</p

Contenidos transmedia de las teleseries españolas: clasificación, análisis y panorama en 2013

En este artículo analizamos los contenidos transmedia que tienen como “nave nodriza” las series programadas por las cadenas de televisión tanto nacionales (La 1, Antena 3, Telecinco) como autonómicas (TV3, ETB, TVG, Canal Sur) con producción propia y de estreno en 2013. Son en total 33 títulos, entre los que se encuentran Aída, Frágiles, La que se avecina (Telecinco); El barco, Bandolera, Amar es para siempre, El tiempo entre costuras (Antena 3); Cuéntame, Gran Reserva, Isabel, Águila Roja (La 1), La riera, Polseres vermelles (TV3); DHB, Goenkale (ETB); Matalobos, Padre Casares (TVG) y Arrayán y Flamán (Canal Sur). Hacemos un repaso de los sites de las series, donde se concentran los contenidos transmedia, y proponemos una clasificación de la gran variedad de formatos encontrados, recurriendo a las distintas categorías de touchpoints que permiten el contacto del receptor con la narración televisiva fuera de la pequeña pantalla. Los resultados apuntan a una presencia abrumadora de los contenidos reenvasados o adaptados al nuevo medio o plataforma y a una escasa todavía expansión transmedial con contenidos inéditos, diferenciados por medio y narrativamente relevantes

Laser texturing to control the wettability of materials

Many applications of different materials are related to the properties of their surface. Wettability is a key property affecting applications in all fields: adhesives, lubricants, detergents, all types of coatings, implant integration, heat transmission, corrosion, etc. Laser texturing has been demonstrated to be an excellent technique to modify surface wettability of many different materials: polymers, metals, ceramics, or even natural stones. The relative simplicity and robustness of the results, together with the widespread availability of affordable industrial laser sources made laser texturing a very promising tool for modifying the surface of parts in manufacturing plants. In this paper we introduce the basics of the technique and show some examples of applications. On one hand, treating the surface of different polymers for biomedical applications. And on the other hand, the production of surfaces with extreme wettability properties is shown: superhydrophilic, superhydrophobic and omniphobic surfaces were obtained by laser texturing

Heart transplantation using allografts from older donors: multicenter study results

33rd Annual Meeting and Scientific Session of the International Society for Heart and Lung Transplantation, April 24–27, 2013, Montreal, Canada.[Abstract] Background. The lengthy waiting time for heart transplantation is associated with high mortality. To increase the number of donors, new strategies have emerged, including the use of hearts from donors ≥50 years old. However, this practice remains controversial. The aim of this study was to evaluate outcomes of patients receiving heart transplants from older donors. Methods. We retrospectively analyzed 2,102 consecutive heart transplants in 8 Spanish hospitals from 1998 to 2010. Acute and overall mortality were compared in patients with grafts from donors ≥50 years old versus grafts from younger donors. Results. There were 1,758 (84%) transplanted grafts from donors < 50 years old (Group I) and 344 (16%) from donors ≥50 years old (Group II). Group I had more male donors than Group II (71% vs 57%, p = 0.0001). The incidence of cardiovascular risk factors was higher in older donors. There were no differences in acute mortality or acute rejection episodes between the 2 groups. Global mortality was higher in Group II (rate ratio, 1.40; 95% confidence interval, 1.18–1.67; p = 0.001) than in Group I. After adjusting for donor cause of death, donor smoking history, recipient age, induction therapy, and cyclosporine therapy, the differences lost significance. Group II had a higher incidence of coronary allograft vasculopathy at 5 years (rate ratio, 1.67; 95% confidence interval, 1.22–2.27; p = 0.001). Conclusions. There were no differences in acute and overall mortality after adjusting for confounding factors. However, there was a midterm increased risk of coronary allograft vasculopathy with the use of older donors. Careful selection of recipients and close monitoring of coronary allograft vasculopathy are warranted in these patients.Instituto de Salud Carlos III; RD12/0042/00

On-surface self-organization of a robust metal-organic cluster based on copper(i) with chloride and organosulphur ligands

Direct sublimation of a Cu4Cl4 metal-organic cluster on Cu(110) under ultra-high vacuum allows the formation of ultra-large well-organized metal-organic supramolecular wires. Our results show that the large monomers assemble with each other by π-π interactions connecting dipyrimidine units and are stabilized by the surfaceWe thank Spanish MINECO (Grants: MAT2013-46753-C2-1-P, MAT2013-47878-C2-1-R and MAT2011-26534) for financial support. JIM acknowledges a CSIC-JaeDoc fellowship, cofunded by ES

Nueva economía 20+20

276 p : il.El fuerte avance de las Tecnologías de la Información y las Comunicaciones (TIC) ha provocado profundos cambios económicos, sociales y culturales en las últimas décadas (Cohen, De Long y Zysman, 2000). La gran velocidad con la que se ha producido este cambio ha quedado reflejada en cifras, como el avance de Internet que, desde 1969, fecha de su nacimiento, hasta la actualidad, se ha extendido a más del 25% de la población mundial, con más de 1.700 millones de usuarios en todo el mundo, siendo especialmente significativos los casos de Europa y Estados Unidos, con penetraciones del 52% y 74,2%, respectivamente (Internet World Stats, 2009). Es igualmente significativo el fuerte crecimiento experimentado por los ordenadores personales que, desde 1977, año en el que vio la luz el primero de ellos, se estima que alcanzaron los 1.000 millones en el 2008, y se hacen predicciones de que se doblará dicha cifra en torno al año 2014 (Gartner, 2008). El trabajo, el ocio, el transporte o, incluso, las relaciones personales se encuentran en un proceso de cambio permanente debido a la profunda influencia que estas tecnologías han tenido sobre la sociedad. Tanto es así que en la nueva realidad, a la que el conocimiento y la tecnología trasladan al ser humano, existen nuevas concepciones del tiempo o del espacio (Castells, 2005). Desde el punto de vista económico, se han producido cambios en la estructura mundial que han desembocado en una nueva economía. Por una parte, las nuevas tecnologías han transformado la economía tradicional, dando lugar a una compleja estructura interconectada de forma global, en la que el desarrollo de las comunicaciones ha jugado un papel fundamental. Adicionalmente, la incorporación de la tecnología en el proceso productivo ha transformado elementos tales como la localización, el tamaño, las estructuras o las relaciones entre las empresas (Brynjolfsson y Kahln, 2000). Por otra parte, las nuevas tecnologías dan lugar a un nuevo mercado de enormes dimensiones, formado por todos aquellos bienes y servicios que dependen de forma crítica de las tecnologías digitales o lo son en sí mismas, lo cual constituye la base de la economía digital (Kling y Lamb, 1999). Con todo ello, el presente informe se encarga, en primer lugar, de identificar en qué consiste la economía digital y cuáles son sus principales componentes. En el siguiente apartado se intenta medir la importancia de este sector, a través de los datos más significativos, que reflejan el crecimiento que dicho sector de la economía ha sufrido en los últimos años, y la importancia relativa del mismo respecto al resto de los sectores. A continuación se presenta una caracterización de los perfiles de empresa que constituyen la economía digital y se busca plantear, después, un modelo de variables significativas que nos permita medir de forma adecuada el sector.Esta publicación ha contado con la cofinancia- ción del Fondo Social Europeo a través del Pro- grama Operativo Plurirregional de Adaptabili- dad y Empleo 2007-2013.ÍNDICE Capítulo 0 EL PROYECTO SECTORES DE LA NUEVA ECONOMÍA 20+20 Capítulo 1 LA ECONOMÍA DIGITAL 1 Introducción 2 ¿Qué es la economía digital? 3 Importancia de la economía digital 4 Las empresas de la economía digital 5 ¿Cómo analizar la economía digital? 6 Conclusiones Capítulo 2 EXPERIENCIAS EMPRESARIALES 11870.COM AGNITIO ASPgems BARRABESBIZ BITDEFENDER BUONGIORNO BUYVIP COMEX GRUPO IBÉRICA DAEDALUS DEIMOS SPACE EPTISA TI ÍNCIPY ISDE ING KERAJET LA CIGÜEÑA DEL BEBÉ MICROGÉNESIS QAPACITY ÍNDICE TERRITORIO CREATIVO TOPRURAL TYVEN Capítulo 3 CONCLUSIONES Capítulo 4 BIBLIOGRAFÍ

Level of blood pressure control in a hypertensive population when measurements are performed outside the clinical setting

Background: To determine whether the number of optimally controlled hypertensive patients is higher using self-measurement of blood pressure at home and ambulatory monitoring, compared to using conventional blood pressure measurements at the doctor&#8217;s office. Method: An observational, cross-sectional, multicentre, descriptive study of a random sample of 237 primary health care patients, known to be hypertensive, from Badajoz (Spain). Blood pressure was measured at the doctor&#8217;s office and by self-measurement at home. Those patients showing good control by self-measurement were subjected to 24-hour ambulatory monitoring. Optimal control was understood as blood pressure < 140/90 mm Hg when measured at the doctor&#8217;s office, and < 135/85 mm Hg when self-measured at home and by daytime ambulatory monitoring. Results: Mean systolic/diastolic measurements at the doctor&#8217;s office and by self-measurement were 145.6/83.9 and 134.0/78.7 mm Hg, respectively (p < 0.000). In the population optimally controlled by self-measurement and who subsequently received ambulatory monitoring, the mean blood pressure was 121.8/73.4 and 125.6/76.2 mm Hg, respectively (p = 0.002; p < 0.000). When measured at the doctor&#8217;s office blood pressure was controlled in about 29.5% (95% CI 23.7-35.3%) of patients, in 38% when self-measured (95% CI 31.4-44.2%; p < 0.000), and in 24.5% when it was confirmed through ambulatory monitoring (95% CI 15.4-33.6%). Sensitivity and positive predictive values of the office measurements for the detection of patients who were well-controlled by self-measurement were 50% and 64.3%, respectively, and 53.4% and 73.8% as regards ambulatory monitoring. Conclusions: A higher level of control is achieved with self-measurement at home not confirmed by ambulatory monitoring. Therefore, the white coat effect does not seem to influence the percentage of well-controlled patients detected at the doctor&#8217;s office. Office blood pressure does not appear to be useful in distinguishing which individual patients are optimally controlled