Structural trends from a consistent set of single-crystal data of REFeAsO (RE = La, Ce, Pr, Nd, Sm, Gd, and Tb)

A new crystal growth technique for single-crystals of REFeAsO (RE = La, Ce, Pr, Nd, Sm, Gd, and Tb) using NaI/KI as flux is presented. Crystals with a size up to 300 $\mu$m were isolated for single-crystal X-ray diffraction measurements. Lattice parameters were determined by LeBail fits of X-ray powder data against LaB6 standard. A consistent set of structural data is obtained and interpreted in a hard-sphere model. Effective radii for the rare-earth metal atoms for REFeAsO are deduced. The relation of the intra- and inter-plane distances of the arsenic atoms is identified as limiter of the phase formation, and its influence on Tc is discussed.Comment: 8 pages, 11 figures, 3 tables, fig. 6 changed to numerical plot, minor changes to the text, accepted for publication in PR

Anisotropic electrical resistivity of LaFeAsO: evidence for electronic nematicity

Single crystals of LaFeAsO were successfully grown out of KI flux. Temperature dependent electrical resistivity was measured with current flow along the basal plane, \rho_perpend(T), as well as with current flow along the crystallographic c-axis, \rho_parallel(T), the latter one utilizing electron beam lithography and argon ion beam milling. The anisotropy ratio was found to lie between \rho_parallel/\rho_perpend = 20 - 200. The measurement of \rho_perpend(T) was performed with current flow along the tetragonal [1 0 0] direction and along the [1 1 0] direction and revealed a clear in-plane anisotropy already at T \leq 175 K. This is significantly above the orthorhombic distortion at T_0 = 147 K and indicates the formation of an electron nematic phase. Magnetic susceptibility and electrical resistivity give evidence for a change of the magnetic structure of the iron atoms from antiferromagnetic to ferromagnetic arrangement along the c-axis at T^\ast = 11 K.Comment: 10 pages, 6 figures, minor change

Dimensionless scaling of heat-release-induced planar shock waves in near-critical CO2

We performed highly resolved one-dimensional fully compressible Navier-Stokes simulations of heat-release-induced compression waves in near-critical CO2. The computational setup, inspired by the experimental setup of Miura et al., Phys. Rev. E, 2006, is composed of a closed inviscid (one-dimensional) duct with adiabatic hard ends filled with CO2 at three supercritical pressures. The corresponding initial temperature values are taken along the pseudo-boiling line. Thermodynamic and transport properties of CO2 in near-critical conditions are modeled via the Peng-Robinson equation of state and Chung's Method. A heat source is applied at a distance from one end, with heat release intensities spanning the range 10^3-10^11 W/m^2, generating isentropic compression waves for values < 10^9 W/m^2. For higher heat-release rates such compressions are coalescent with distinct shock-like features (e.g. non-isentropicity and propagation Mach numbers measurably greater than unity) and a non-uniform post-shock state is present due to the strong thermodynamic nonlinearities. The resulting compression wave intensities have been collapsed via the thermal expansion coefficient, highly variable in near-critical fluids, used as one of the scaling parameters for the reference energy. The proposed scaling applies to isentropic thermoacoustic waves as well as shock waves up to shock strength 2. Long-term time integration reveals resonance behavior of the compression waves, raising the mean pressure and temperature at every resonance cycle. When the heat injection is halted, expansion waves are generated, which counteract the compression waves leaving conduction as the only thermal relaxation process. In the long term evolution, the decay in amplitude of the resonating waves observed in the experiments is qualitatively reproduced by using isothermal boundary conditions.Comment: As submitted to AIAA SciTech 2017, available at http://arc.aiaa.org/doi/pdf/10.2514/6.2017-008

Tetragonal to Orthorhombic Transition of GdFeAsO Studied by Single-Crystal Synchrotron X-Ray Diffraction

A study of the tetragonal to orthorhombic phase transition of GdFeAsO is presented. Planes of the reciprocal space were reconstructed form single-crystal synchrotron X-ray diffraction data. By cooling below the structural transition temperature splitting of the Bragg reflections was observed corresponding to four different twin domain orientations. A model was developed to quantify the distortion of the lattice from the position of the splitted reflections relative to each other. Constrained 2D-Cauchy fits of several splitted reflections provided positions of the reflections. The influence of the structural distortion was detectable already above the structural transition temperature hinting at fluctuations in the tetragonal phase.Comment: 6 pages, 6 figure

Experimental and numerical results of active flow control on a highly loaded stator cascade

Dieser Beitrag ist mit Zustimmung des Rechteinhabers aufgrund einer (DFG geförderten) Allianz- bzw. Nationallizenz frei zugänglich.This publication is with permission of the rights owner freely accessible due to an Alliance licence and a national licence (funded by the DFG, German Research Foundation) respectively.This article presents experimental and numerical results for a compressor cascade with active flow control. Steady and pulsed blowing has been used to control the secondary flow and separation characteristics of a highly loaded controlled diffusion airfoil. Investigations were performed at the design incidence for blowing ratios from approximately 0.7 to 3.0 (jet-to-inlet velocity) and a Reynolds number of 840 000 (based on axial chord and inlet velocity). Detailed flow field data were collected using a five-hole pressure probe, pressure taps on the blade surfaces, and time-resolved Particle Image Velocimetry. Unsteady Reynolds-averaged Navier–Stokes simulations were performed for a wide range of flow control parameters. The experimental and numerical results are used to understand the interaction between the jet and the passage flow. The benefit of the flow control on the cascade performance is weighted against the costs of the actuation by introducing an efficiency which takes the presence of the jets into account.DFG, SFB 557, Beeinflussung komplexer turbulenter Scherströmunge

Lateral flow–based nucleic acid detection of SARS-CoV-2 using enzymatic incorporation of biotin-labeled dUTP for POCT use

The degree of detrimental effects inflicted on mankind by the COVID-19 pandemic increased the need to develop ASSURED (Affordable, Sensitive, Specific, User-friendly, Rapid and Robust, Equipment-free, and Deliverable) POCT (point of care testing) to overcome the current and any future pandemics. Much effort in research and development is currently advancing the progress to overcome the diagnostic pressure built up by emerging new pathogens. LAMP (loop-mediated isothermal amplification) is a well-researched isothermal technique for specific nucleic acid amplification which can be combined with a highly sensitive immunochromatographic readout via lateral flow assays (LFA). Here we discuss LAMP-LFA robustness, sensitivity, and specificity for SARS-CoV-2 N-gene detection in cDNA and clinical swab-extracted RNA samples. The LFA readout is designed to produce highly specific results by incorporation of biotin and FITC labels to 11-dUTP and LF (loop forming forward) primer, respectively. The LAMP-LFA assay was established using cDNA for N-gene with an accuracy of 95.65%. To validate the study, 82 SARS-CoV-2-positive RNA samples were tested. Reverse transcriptase (RT)-LAMP-LFA was positive for the RNA samples with an accuracy of 81.66%; SARS-CoV-2 viral RNA was detected by RT-LAMP-LFA for as low as CT-33. Our method reduced the detection time to 15 min and indicates therefore that RT-LAMP in combination with LFA represents a promising nucleic acid biosensing POCT platform that combines with smartphone based semi-quantitative data analysis.Peer Reviewe

Ab initio modeling of steady-state and time-dependent charge transport in hole-only α-NPD devices

We present an ab initio modeling study of steady-state and time-dependent charge transport in hole-only devices of the amorphous molecular semiconductor α–NPD [N,N ′ −Di(1–naphthyl)−N,N ′ −diphenyl−(1,1 ′ −biphenyl)−4,4 ′ −diamine] α–NPD [N,N′-Di(1–naphthyl)-N,N′-diphenyl-(1,1′-biphenyl)-4,4′-diamine]. The study is based on the microscopic information obtained from atomistic simulations of the morphology and density functional theory calculations of the molecular hole energies, reorganization energies, and transfer integrals. Using stochastic approaches, the microscopic information obtained in simulation boxes at a length scale of ∼10 nm is expanded and employed in one-dimensional (1D) and three-dimensional (3D) master-equation modeling of the charge transport at the device scale of ∼100 nm. Without any fit parameter, predicted current density-voltage and impedance spectroscopy data obtained with the 3D modeling are in very good agreement with measured data on devices with different α-NPD layer thicknesses in a wide range of temperatures, bias voltages, and frequencies. Similarly good results are obtained with the computationally much more efficient 1D modeling after optimizing a hopping prefacto

Compromised neuroplasticity in cigarette smokers under nicotine withdrawal is restituted by the nicotinic α4β2-receptor partial agonist varenicline

Nicotine modulates neuroplasticity and improves cognitive functions in animals and humans. In the brain of smoking individuals, calcium-dependent plasticity induced by non-invasive brain stimulation methods such as transcranial direct current stimulation (tDCS) and paired associative stimulation (PAS) is impaired by nicotine withdrawal, but partially re-established after nicotine re-administration. In order to investigate the underlying mechanism further, we tested the impact of the α4β2-nicotinic receptor partial agonist varenicline on focal and non-focal plasticity in smokers during nicotine withdrawal, induced by PAS and tDCS, respectively. We administered low (0.3 mg) and high (1.0 mg) single doses of varenicline or placebo medication before stimulation over the left motor cortex of 20 healthy smokers under nicotine withdrawal. Motor cortex excitability was monitored by single-pulse transcranial magnetic stimulation-induced motor evoked potential amplitudes for 36 hours after plasticity induction. Stimulation-induced plasticity was absent under placebo medication, whereas it was present in all conditions under high dose. Low dose restituted only tDCS-induced non-focal plasticity, producing no significant impact on focal plasticity. High dose varenicline also prolonged inhibitory plasticity. These results are comparable to the impact of nicotine on withdrawal-related impaired plasticity in smokers and suggest that α4β2 nicotinic receptors are relevantly involved in plasticity deficits and restitution in smokers