STAT1 activation in association with JAK2 exon 12 mutations

La inclusión de la perspectiva de género en la actividad jurisdiccional es una demanda sostenida de los colectivos feministas y de mujeres, dado que las sentencias tienen un poder performativo y envían un mensaje a la sociedad: “[…] tienen un poder individual y colectivo que impactan en la vida de las personas y conforman la identidad del poder judicial como un actor imprescindible en la construcción de un Estado democrático de derecho” (Suprema Corte de Justicia de la Nación, 2013:7). La incorporación de la perspectiva de género viene a garantizar la igualdad de posiciones (Kessler, 2014) entre mujeres y varones como una meta, trascendiendo la mera igualdad de oportunidades que hasta el presente se ha demostrado insuficiente para que las mujeres consigamos una ciudadanía plena. Al momento de incorporar la perspectiva de género en las sentencias, quienes juzgan deben tener presente en primer lugar, el impacto diferenciado de las normas en base al sexo de las personas. En segundo lugar, la interpretación y aplicación de las leyes en relación con (y en base a) estereotipos de género. Si, por ejemplo, quienes imparten justicia no tienen presentes los estereotipos de género vigentes detrás de las violaciones a los derechos humanos de las mujeres, si no los detectan ni cuestionan, entonces los reproducen. Tal como sostiene Scott (1996) el género es una categoría imprescindible para el análisis social. En tercer lugar, al momento del juzgamiento, se deben tener en cuenta las exclusiones legitimadas por la ley por pensar el mundo en términos binarios y androcéntricos; en cuarto lugar, la distribución no equitativa de recursos y poder que opera entre varones y mujeres en el marco de una organización social patriarcal, y, por último, el trato diferenciado por género legitimado por las propias leyes.Eje 3: Tramas violentas y espacios de exclusión.Instituto de Cultura Jurídic

Light Quark Physics with Dynamical Wilson Fermions

We present results for spectroscopy, quark masses and decay constants obtained from SESAM's and TkL's large statistics simulations of QCD with two dynamical Wilson fermions.Comment: 3 pages; to appear in the proceedings of Lat.'9

QCD thermodynamics with continuum extrapolated dynamical overlap fermions

We study the finite temperature transition in QCD with two flavors of dynamical fermions at a pseudoscalar pion mass of about 350 MeV. We use lattices with temporal extent of $N_t$=8, 10 and 12. For the first time in the literature a continuum limit is carried out for several observables with dynamical overlap fermions. These findings are compared with results obtained within the staggered fermion formalism at the same pion masses and extrapolated to the continuum limit. The presented results correspond to fixed topology and its effect is studied in the staggered case. Nice agreement is found between the overlap and staggered results

Glueballs and string breaking from full QCD

We present results on the static potential, and torelon and glueball masses from simulations of QCD with two flavours of dynamical Wilson fermions on $16^3\times 32$ and $24^3\times 40$ lattices at $\beta=5.6$.Comment: Talk presented by Gunnar Bali at International Symposium on Lattice Field Theories (Lattice 97), Edinburgh, July 1997, 3 pages LaTeX (epscrc2.sty) with 4 eps figure

Spectra of heavy-light and heavy-heavy mesons containing charm quarks, including higher spin states for Nf=2+1N_f=2+ 1

We study the spectra of heavy-light and heavy-heavy mesons containing charm quarks, including higher spin states. We use two sets of $N_f = 2 + 1$ gauge configurations, one set from QCDSF using the SLiNC action, and the other configurations from the Budapest-Marseille-Wuppertal collaboration, using the HEX smeared clover action. To extract information about the excited states, we choose a suitable basis of operators to implement the variational method.Comment: 7 pages, 5 figures, Talk presented at the XXIX International Symposium on Lattice Field Theory, Lattice2011, July 11-16, 2011, The Village at Squaw Valley, California, US

Critical Dynamics of the Hybrid Monte Carlo Algorithm

We investigate the critical dynamics of the Hybrid Monte Carlo algorithm approaching the chiral limit of standard Wilson fermions. Our observations are based on time series of lengths O(5000) for a variety of observables. The lattice sizes are 16^3 x 32 and 24^3 x 40. We work at beta=5.6, and kappa=0.156, 0.157, 0.1575, 0.158, with 0.83 > m_pi/m_rho > 0.55. We find surprisingly small integrated autocorrelation times for local and extended observables. The dynamical critical exponent $z$ of the exponential autocorrelation time is compatible with 2. We estimate the total computational effort to scale between V^2 and V^2.25 towards the chiral limit.Comment: 3 pages, Latex with espcrc2.sty and postscript figures, Talk given at Lattice 9

Unquenched QCD with Light Quarks

We present recent results in unquenched lattice QCD with two degenerate light sea quarks using the truncated determinant approximation (TDA). In the TDA the infrared modes contributing to the quark determinant are computed exactly up to some cutoff in quark off-shellness (typically 2$\Lambda_{QCD}$). This approach allows simulations to be performed at much lighter quark masses than possible with conventional hybrid MonteCarlo techniques. Results for the static energy and topological charge distributions are presented using a large ensemble generated on very coarse (6$^4$) but physically large lattices. Preliminary results are also reported for the static energy and meson spectrum on 10$^3$x20 lattices (lattice scale $a^{-1}$=1.15 GeV) at quark masses corresponding to pions of mass $\leq$ 200 MeV. Using multiboson simulation to compute the ultraviolet part of the quark determinant the TDA approach becomes an exact with essentially no increase in computational effort. Some preliminary results using this fully unquenched algorithm are presented.Comment: LateX, 39 pages, 16 eps figures, 1 ps figur

Evidence for a bound on the lifetime of de Sitter space

Recent work has suggested a surprising new upper bound on the lifetime of de Sitter vacua in string theory. The bound is parametrically longer than the Hubble time but parametrically shorter than the recurrence time. We investigate whether the bound is satisfied in a particular class of de Sitter solutions, the KKLT vacua. Despite the freedom to make the supersymmetry breaking scale exponentially small, which naively would lead to extremely stable vacua, we find that the lifetime is always less than about exp(10^(22)) Hubble times, in agreement with the proposed bound.Comment: 28 page

Organ Support Therapy in the Intensive Care Unit and Return to Work in Out-of-Hospital Cardiac Arrest Survivors:a Nationwide Cohort Study

AIM: With increased survival after out-of-hospital cardiac arrest (OHCA), impact of the post-resuscitation course has become important. Among 30-day OHCA survivors, we investigated associations between organ support therapy in the Intensive Care Unit (ICU) and return to work.METHODS: This Danish nationwide cohort-study included 30-day-OHCA-survivors who were employed prior to arrest. We linked OHCA data to information on in-hospital care and return to work. For patients admitted to an ICU and based on renal replacement therapy (RRT), cardiovascular support and mechanical ventilation, we assessed the prognostic value of organ support therapies in multivariable Cox regression models.RESULTS: Of 1,087 30-day survivors, 212 (19.5%) were treated in an ICU with 0-1 types of organ support, 494 (45.4%) with support of two organs, 26 (2.4%) with support of three organs and 355 (32.7%) were not admitted to an ICU. Return to work increased with decreasing number of organs supported, from 53.8% (95% CI: 49.5-70.1%) in patients treated with both RRT, cardiovascular support and mechanical ventilation to 88.5% (95% CI: 85.1-91.8%) in non-ICU-patients. In 732 ICU-patients, ICU-patients with support of 3 organs had significantly lower adjusted hazard ratios (HR) of returning to work (0.50 [95% CI: 0.30-0.85] compared to ICU-patients with support of 0-1 organ. The corresponding HR was 0.48 [95% CI: 0.30-0.78] for RRT alone.CONCLUSIONS: In 30-day survivors of OHCA, number of organ support therapies and in particular need of RRT were associated with reduced rate of return to work, although more than half of these latter patients still returned to work.</p