725 research outputs found
Determination of total plasma hydroperoxides using a diphenyl-1- pyrenylphosphine fluorescent probe
Plasma hydroperoxides (HPs) are widely accepted to be good indicators of oxidative stress. By means of the method proposed here, which uses diphenyl-1-pyrenylphosphine (DPPP) as a fluorescent probe, all types of plasma HP were determined. The limits of detection and quantification of the method were 0.08 and 0.25 nmol of cumene hydroperoxide (CHP) equivalents in 40 μl of plasma, respectively. The method is satisfactory in terms of precision (5.3% for 14.5 μM CHP eq., n = 8), and the recoveries were 91% and 92% after standard additions of 26 and 52 μM CHP, respectively. The selectivity of the proposed method is higher than 96%. Moreover, optimization of the reaction conditions and the addition of ethylenediaminetetraacetic acid (EDTA) disodium salt and 2,6-di-tert-butyl-4-methylphenol (BHT) prevented the formation of HP artifacts during the analysis. Therefore, the proposed method is useful for simple and quantitative determination of total plasma HPs. © 2012 Elsevier Inc. All rights reserved.Peer Reviewe
Solidification of small para-H2 clusters at zero temperature
We have determined the ground-state energies of para-H clusters at zero
temperature using the diffusion Monte Carlo method. The liquid or solid
character of each cluster is investigated by restricting the phase through the
use of proper importance sampling. Our results show inhomogeneous
crystallization of clusters, with alternating behavior between liquid and solid
phases up to N=55. From there on, all clusters are solid. The ground-state
energies in the range N=13--75 are established and the stable phase of each
cluster is determined. In spite of the small differences observed between the
energy of liquid and solid clusters, the corresponding density profiles are
significantly different, feature that can help to solve ambiguities in the
determination of the specific phase of H clusters.Comment: 17 pages, accepted for publication in J. Phys. Chem.
Ca impurity in small mixed He-He clusters
The structure of small mixed helium clusters doped with one calcium atom has
been determined within the diffusion Monte Carlo framework. The results show
that the calcium atom sits at the He-He interface. This is in agreement
with previous studies, both experimental and theoretical, performed for large
clusters. A comparison between the results obtained for the largest cluster we
have considered for each isotope shows a clear tendency of the Ca atom to
reside in a deep dimple at the surface of the cluster for He clusters, and
to become fully solvated for He clusters. We have calculated the absorption
spectrum of Ca around the transition and have found that
it is blue-shifted from that of the free-atom transition by an amount that
depends on the size and composition of the cluster.Comment: 24 pages, 11 figures. Accepted on Journal of Chemical Physic
Microscopic study of the He2-SF6 trimers
The He2-SF6 trimers, in their different He isotopic combinations, are studied
both in the framework of the correlated Jastrow approach and of the Correlated
Hyperspherical Harmonics expansion method. The energetics and structure of the
He-SF6 dimers are analyzed, and the existence of a characteristic rotational
band in the excitation spectrum is discussed, as well as the isotopic
differences. The binding energies and the spatial properties of the trimers, in
their ground and lowest lying excited states, obtained by the Jastrow ansatz
are in excellent agreement with the results of the converged CHH expansion. The
introduction of the He-He correlation makes all trimers bound by largely
suppressing the short range He-He repulsion.
The structural properties of the trimers are qualitatively explained in terms
of the shape of the interactions, Pauli principle and masses of the
constituents.Comment: 17 pages, 5 figures. Submitted to PR
Equation of state of low--density neutron matter and the pairing gap
We report results of the equation of state of neutron matter in the
low--density regime, where the Fermi wave vector ranges from . Neutron matter in this regime is superfluid because of
the strong and attractive interaction in the channel. The properties of
this superfluid matter are calculated starting from a realistic Hamiltonian
that contains modern two-- and three--body interactions. The ground state
energy and the superfluid energy gap are calculated using the Auxiliary
Field Diffusion Monte Carlo method. We study the structure of the ground state
by looking at pair distribution functions as well as the Cooper-pair wave
function used in the calculations.Comment: 12 pages, 7 figure
Silicon-based three-dimensional microstructures for radiation dosimetry in hadrontherapy
In this work, we propose a solid-state-detector for use in radiation microdosimetry. This device improves the performance of existing dosimeters using customized 3D-cylindrical microstructures etched inside silicon. The microdosimeter consists of an array of micro-sensors that have 3D-cylindrical electrodes of 15 μm diameter and a depth of 5 μm within a silicon membrane, resulting in a well-defined micrometric radiation sensitive volume. These microdetectors have been characterized using an 241Am source to assess their performance as radiation detectors in a high-LET environment. This letter demonstrates the capability of this microdetector to be used to measure dose and LET in hadrontherapy centers for treatment plan verification as part of their patient-specific quality control program
Ground state properties of a dilute homogeneous Bose gas of hard disks in two dimensions
The energy and structure of a dilute hard-disks Bose gas are studied in the
framework of a variational many-body approach based on a Jastrow correlated
ground state wave function. The asymptotic behaviors of the radial distribution
function and the one-body density matrix are analyzed after solving the Euler
equation obtained by a free minimization of the hypernetted chain energy
functional. Our results show important deviations from those of the available
low density expansions, already at gas parameter values . The
condensate fraction in 2D is also computed and found generally lower than the
3D one at the same .Comment: Submitted to PRA. 7 pages and 8 figure
State-dependent Jastrow correlation functions for 4He nuclei
We calculate the ground-state energy for the nucleus 4He with V4 nucleon
interactions, making use of a Jastrow description of the corresponding
wavefunction with state-dependent correlation factors. The effect related to
the state dependence of the correlation is quite important, lowering the upper
bound for the ground-state energy by some 2 MeV.Comment: 10 pages, REVTeX, to be published in J. Phys. G: Nucl. Part. Phy
Primula hirsuta All. dans les Pyrénées orientales
Confirmem la presència d’aquesta espècie als Pirineus Orientals basant-nos en noves recol•leccions i observacions de camp. A més a més, presentem una revisió crítica de les citacions anteriors i dels testimonis d’herbari existents. Finalment, resumim la corologia d’aquesta espècie als Pirineus i concloem que hauria d’ésser considerada com a vulnerable (VU) a Catalunya seguint els criteris de l’UICN.Our new collections and field observations confirm the presence of this species in the Eastern Pyrenees. Moreover, we present a critical revision of the previous doubtful citations and of the extant herbarium sheets. Finally, we sum up the chorology of the species on the Pyrenean range and we conclude that the species should be considered as vulnerable (VU) in Catalonia according to criteria UICN.Nos nouvelles récoltes et données de terrain confirment la présence de cette espèce dans la partie orientale des Pyrénées, mise en doute dans quelques travaux ibériques récents. Aussi, nous présentons une révision critique des citations antérieures et des échantillons d’herbier existants. Nous résumons la chorologie de cette espèce dans les Pyrénées et concluons au final que le statut de conservation de ce taxon en Catalogne est vulnérable (VU) selon les critères de l’UICN
ECU-oriented models for NOx prediction. Part 2: adaptive estimation by using an NOx sensor
The implantation of nitrogen oxide sensors in diesel engines is necessary in order to track emissions at the engine exhaust line for diagnosis and control of the after-treatment devices. However, the use of models is still necessary since the sensor outputs are delayed and filtered. The present paper deals with the problem of the nitrogen oxide estimation in two parts; Part 1 deals with a control-oriented model for the nitrogen oxide estimation, while Part 2 presents data fusion of the model and the sensor to improve the estimation, which is presented in the following. The use of models for the nitrogen oxide estimation is an alternative but the drift and the ageing are still issues. In order to overcome this problem, the fusion of different signals can be carried out in a smart way by means of a Kalman filter. There exist different ways of presenting this fusion, from directly tracking the bias to updating the model parameters. For this, different algorithms are proposed in this paper with the aim of correcting the model output. Furthermore, the estimation of the actual nitrogen oxide concentration, by preventing sensor delay and filtering, is also integrated in the algorithm, which is a suitable strategy for combining nitrogen oxide sensors and models on an onboard basis.Guardiola, C.; Climent, H.; Pla Moreno, B.; Blanco-Rodriguez, D. (2015). ECU-oriented models for NOx prediction. Part 2: adaptive estimation by using an NOx sensor. Proceedings of the Institution of Mechanical Engineers, Part D: Journal of Automobile Engineering. 229(10):1345-1360. doi:10.1177/0954407014561278S134513602291
- …