Developments in impact damage modeling for laminated composite structures

Damage tolerance is the most critical technical issue for composite fuselage structures studied in the Advanced Technology Composite Aircraft Structures (ATCAS) program. The objective here is to understand both the impact damage resistance and residual strength of the laminated composite fuselage structure. An understanding of the different damage mechanisms which occur during an impact event will support the selection of materials and structural configurations used in different fuselage quadrants and guide the development of analysis tools for predicting the residual strength of impacted laminates. Prediction of the damage state along with the knowledge of post-impact response to applied loads will allow for engineered stacking sequencies and structural configurations; intelligent decisions on repair requirements will also result

Outlier detection in network revenue management

This paper presents an automated approach for providing ranked lists of outliers in observed demand to support analysts in network revenue management. Such network revenue management, e.g. for railway itineraries, needs accurate demand forecasts. However, demand outliers across or in parts of a network complicate accurate demand forecasting, and the network structure makes such demand outliers hard to detect. We propose a two-step approach combining clustering with functional outlier detection to identify outlying demand from network bookings observed on the leg level. The first step clusters legs to appropriately partition and pool booking patterns. The second step identifies outliers within each cluster and uses a novel aggregation method across legs to create a ranked alert list of affected instances. Our method outperforms analyses that consider leg data without regard for network implications and offers a computationally efficient alternative to storing and analysing all data on the itinerary level, especially in highly-connected networks where most customers book multi-leg products. A simulation study demonstrates the robustness of the approach and quantifies the potential revenue benefits from adjusting demand forecasts for offer optimisation. Finally, we illustrate the applicability based on empirical data obtained from Deutsche Bahn

Impact damage resistance of composite fuselage structure, part 2

The strength of laminated composite materials may be significantly reduced by foreign object impact induced damage. An understanding of the damage state is required in order to predict the behavior of structure under operational loads or to optimize the structural configuration. Types of damage typically induced in laminated materials during an impact event include transverse matrix cracking, delamination, and/or fiber breakage. The details of the damage state and its influence on structural behavior depend on the location of the impact. Damage in the skin may act as a soft inclusion or affect panel stability, while damage occurring over a stiffener may include debonding of the stiffener flange from the skin. An experiment to characterize impact damage resistance of fuselage structure as a function of structural configuration and impact threat was performed. A wide range of variables associated with aircraft fuselage structure such as material type and stiffener geometry (termed, intrinsic variables) and variables related to the operating environment such as impactor mass and diameter (termed, extrinsic variables) were studied using a statistically based design-of-experiments technique. The experimental design resulted in thirty-two different 3-stiffener panels. These configured panels were impacted in various locations with a number of impactor configurations, weights, and energies. The results obtained from an examination of impacts in the skin midbay and hail simulation impacts are documented. The current discussion is a continuation of that work with a focus on nondiscrete characterization of the midbay hail simulation impacts and discrete characterization of impact damage for impacts over the stiffener

Knowledge of oral cancer risk factors amongst high-risk Australians: findings from the LESIONS programme

Patient awareness of risk factors associated with cancer has been shown to increase patient presentation for screening and early detection. This study aimed to identify the level of awareness of oral cancer risk factors in a high risk Australian population.Participants were recruited from the LESIONS programme between April 2012 and April 2014. Demographics were collected via semi-structured interview. A self-administered questionnaire was provided, listing a number of possible oral cancer risk factors. Participants were requested to indicate their level of agreement on a three-point scale. Bivariate and multivariable analysis was performed.A total of 1498 participants took part in the LESIONS programme and were invited to complete the questionnaire. The most common risk factors thought to be associated with oral cancer were smoking (87.5%), poor oral hygiene (67.9%) and family history (61.1%). Only 50.2% of respondents were aware of alcohol consumption as a risk factor.While most participants were aware of the association between smoking and oral cancer, only half were aware of the significant risk alcohol consumption poses. A significant portion of participants also held a number of inaccurate beliefs in relation to oral cancer risk. These findings can benefit both clinicians and public health policy makers in targeting oral cancer education

Torque: topology-free querying of protein interaction networks

Torque is a tool for cross-species querying of protein–protein interaction networks. It aims to answer the following question: given a set of proteins constituting a known complex or a pathway in one species, can a similar complex or pathway be found in the protein network of another species? To this end, Torque seeks a matching set of proteins that are sequence similar to the query proteins and span a connected region of the target network, while allowing for both insertions and deletions. Unlike existing approaches, Torque does not require knowledge of the interconnections among the query proteins. It can handle large queries of up to 25 proteins. The Torque web server is freely available for use at http://www.cs.tau.ac.il/∼bnet/torque.html

Rapid method of obtaining area under curve for any compartment of any linear pharmacokinetic model in terms of rate constants

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/45066/1/10928_2005_Article_BF01063618.pd

Temperature dependence of electrical properties of electrodeposited Ni-based nanowires

The influence of annealing on the microstructure and the electrical properties of cylindrical nickel-based nanowires has been investigated. Nanowires of nickel of nominally 200 nm diameter and of permalloy (Py) of nominally 70 nm were fabricated by electrochemical deposition into nanoporous templates of polycarbonate and anodic alumina, respectively. Characterization was carried out on as-grown nanowires and nanowires heat treated at 650°C. Transmission electron microscopy and diffraction imaging of as-grown and annealed nanowires showed temperature-correlated grain growth of an initially nano-crystalline structure with ≤8 nm (Ni) and ≤20 nm (Py) grains towards coarser poly-crystallinity with grain sizes up to about 160 nm (Ni) and 70 nm (Py), latter being limited by the nanowire width. The electrical conductivity of individual as-grown and annealed Ni nanowires was measured in situ within a scanning electron microscope environment. At low current densities, the conductivity of annealed nanowires was estimated to have risen by a factor of about two over as-grown nanowires. We attribute this increase, at least in part, to the observed grain growth. The annealed nanowire was subsequently subjected to increasing current densities. Above 120 kA mm -2 the nanowire resistance started to rise. At 450 kA mm -2 the nanowire melted and current flow ceased

Impact damage resistance of composite fuselage structure, part 1

The impact damage resistance of laminated composite transport aircraft fuselage structures was studied experimentally. A statistically based designed experiment was used to examine numerous material, laminate, structural, and extrinsic (e.g., impactor type) variables. The relative importance and quantitative measure of the effect of each variable and variable interactions on responses including impactor dynamic response, visibility, and internal damage state were determined. The study utilized 32 three-stiffener panels, each with a unique combination of material type, material forms, and structural geometry. Two manufacturing techniques, tow placement and tape lamination, were used to build panels representative of potential fuselage crown, keel, and lower side-panel designs. Various combinations of impactor variables representing various foreign-object-impact threats to the aircraft were examined. Impacts performed at different structural locations within each panel (e.g., skin midbay, stiffener attaching flange, etc.) were considered separate parallel experiments. The relationship between input variables, measured damage states, and structural response to this damage are presented including recommendations for materials and impact test methods for fuselage structure

A development cooperation Erasmus Mundus partnership for capacity building in earthquake mitigation science and higher education

Successful practices have shown that a community’s capacity to manage and reduce its seismic risk relies on capitalization on policies, on technology and research results. An important role is played by education, than contribute to strengthening technical curricula of future practitioners and researchers through university and higher education programs. EUNICE is a European Commission funded higher education partnership for international development cooperation with the objective to build capacity of individuals who will operate at institutions located in seismic prone Asian Countries. The project involves five European Universities, eight Asian universities and four associations and NGOs active in advanced research on seismic mitigation, disaster risk management and international development. The project consists of a comprehensive mobility scheme open to nationals from Afghanistan, Bangladesh, China, Nepal, Pakistan, Thailand, Bhutan, India, Indonesia, Malaysia, Maldives, North Korea, Philippines, and Sri Lanka who plan to enroll in school or conduct research at one of five European partner universities in Italy, Greece and Portugal. During the 2010-14 time span a total number of 104 mobilities are being involved in scientific activities at the undergraduate, masters, PhD, postdoctoral and academic-staff exchange levels. Researchers, future policymakers and practitioners build up their curricula over a range of disciplines in the fields of earthquake engineering, seismology, disaster risk management and urban planning

EU-NICE, Eurasian University Network for International Cooperation in Earthquakes

Despite the remarkable scientific advancements of earthquake engineering and seismology in many countries, seismic risk is still growing at a high rate in the world’s most vulnerable communities. Successful practices have shown that a community’s capacity to manage and reduce its seismic risk relies on capitalization on policies, on technology and research results. An important role is played by education, than contribute to strengthening technical curricula of future practitioners and researchers through university and higher education programmes. In recent years an increasing number of initiatives have been launched in this field at the international and global cooperation level. Cooperative international academic research and training is key to reducing the gap between advanced and more vulnerable regions. EU-NICE is a European Commission funded higher education partnership for international development cooperation with the objective to build capacity of individuals who will operate at institutions located in seismic prone Asian Countries. The project involves five European Universities, eight Asian universities and four associations and NGOs active in advanced research on seismic mitigation, disaster risk management and international development. The project consists of a comprehensive mobility scheme open to nationals from Afghanistan, Bangladesh, China, Nepal, Pakistan, Thailand, Bhutan, India, Indonesia, Malaysia, Maldives, North Korea, Philippines, and Sri Lanka who plan to enrol in school or conduct research at one of five European partner universities in Italy, Greece and Portugal. During the 2010-14 time span a total number of 104 mobilities are being involved in scientific activities at the undergraduate, masters, PhD, postdoctoral and academic-staff exchange levels. This high number of mobilities and activities is selected and designed so as to produce an overall increase of knowledge that can result in an impact on earthquake mitigation. Researchers, future policymakers and practitioners build up their curricula over a range of disciplines in the fields of engineering, seismology, disaster risk management and urban planning. Specific educational and research activities focus on earthquake risk mitigation related topics such as: anti-seismic structural design, structural engineering, advanced computer structural collapse analysis, seismology, experimental laboratory studies, international and development issues in disaster risk management, social-economical impact studies, international relations and conflict resolution