532 research outputs found
Charge redistribution in electrochemically-actuated mechanical sensors
International audienceMany proofs of concept studies have established the mechanical sensitivity of functionalized microcantilevers to a large spectrum of target molecules. However, moving to real-life applications also requires the monitored mechanical effect to be highly specific. Moving towards more specificity in cantilever-based sensing, monitoring the mechanical response of electrochemically actuated microcantilevers is then thought to provide a fast, reliable and complementary experimental information to the long-time cantilever bending measurement for the detection of target molecules. Full-field measurements are therefore used to investigate the way the electro-elastic coupling is altered when a microcantilever undergoes decane-thiol adsorption. The proposed technique reveals that the latter results in a charge density redistribution along the cantilever in addition to the local surface passivation. Focusing on the cantilever tip displacement under electrochemical actuation, this redistribution partially compensates the electro-elastic coupling alteration due to the surface passivation, therefore possibly yielding an ambiguous detection result. This effect should be taken into account for the optimal design of specific electrochemically actuated mechanical sensors
Multiple wavelengths reflectance microscopy to study the multi-physical behavior of MEMS
International audienceIn order to characterize surface chemomechanical driving micro-electro-mechanical systems (MEMS) behavior, we propose herein a method to simultaneously obtain a full kinematic field describing the surface displacement and a map of its chemical modification from optical measurements. Using a microscope, reflected intensity fields are recorded for two different illumination wavelengths. Decoupling the wavelength-independent and -dependent contributions to the measured relative intensity changes then yields the sought fields. This method is applied to the investigation of the electro-elastic coupling, providing images of both the local surface electrical charge density and the device deformation field
Shall We (Math and) Dance?
Can we use mathematics, and in particular the abstract branch of category
theory, to describe some basics of dance, and to highlight structural
similarities between music and dance? We first summarize recent studies between
mathematics and dance, and between music and categories. Then, we extend this
formalism and diagrammatic thinking style to dance.Comment: preprin
Localization and Fingerprint of Radio Signals Employing a Multichannel Photonic Analog-to-Digital Converter
[EN] The fingerprint and localization of radio signals employing a multichannel photonic analog-to-digital converter (ADC) is proposed, analyzed, and demonstrated in a laboratory experiment. The photonic ADC detects the radio signals with high sensitivity in a large bandwidth without down-conversion stages. This is of special interest when processing emerging low-power wireless standards like ultra-wideband (UWB) radio. The optical processing in the multichannel photonic ADC is tailored for the localization and fingerprint of generic radio transmitters when orthogonal-frequency division multiplexing (OFDM) modulation is employed in the transmission. The photonic ADC includes engineered optical and electrical amplification. The experimental work demonstrates that detection of radio signals with -65 dBm power with signal-to-noise ratio better than 20 dB is feasible, which is in good accordance with the theoretical analysis. The multichannel photonic ADC comprises five optical channels which are precisely time-aligned in optical domain achieving 0.23-m spatial resolution (median) in the localization of radio transmitters. The experimental work also demonstrates that photonic-ADC processing is adequate for OFDM-based UWB radio-signal fingerprint including estimation of the average power, frequency band of operation, and time-frequency hopping pattern if applicable. UWB transmitter localization has been experimentally demonstrated with 0.4-m error.This work was supported in part by the European 7th Framework Program Project UCELLS FP7-IST-216785. The work of M. Morant was supported by Spain FPU MEC under Grant AP2007-01413.Llorente, R.; Morant, M.; Puche, JF.; Romme, J.; Amiot, N.; Uguen, B.; Duplicy, J. (2010). Localization and Fingerprint of Radio Signals Employing a Multichannel Photonic Analog-to-Digital Converter. IEEE Transactions on Microwave Theory and Techniques. 58(11):3304-3311. https://doi.org/10.1109/TMTT.2010.2076730S33043311581
Theoretical model for ultracold molecule formation via adaptive feedback control
We investigate pump-dump photoassociation of ultracold molecules with
amplitude- and phase-modulated femtosecond laser pulses. For this purpose a
perturbative model for the light-matter interaction is developed and combined
with a genetic algorithm for adaptive feedback control of the laser pulse
shapes. The model is applied to the formation of 85Rb2 molecules in a
magneto-optical trap. We find for optimized pulse shapes an improvement for the
formation of ground state molecules by more than a factor of 10 compared to
unshaped pulses at the same pump-dump delay time, and by 40% compared to
unshaped pulses at the respective optimal pump-dump delay time. Since our model
yields directly the spectral amplitudes and phases of the optimized pulses, the
results are directly applicable in pulse shaping experiments
Optimizing the photoassociation of cold atoms by use of chirped laser pulses
Photoassociation of ultracold atoms induced by chirped picosecond pulses is
analyzed in a non-perturbative treatment by following the wavepackets dynamics
on the ground and excited surfaces. The initial state is described by a
Boltzmann distribution of continuum scattering states. The chosen example is
photoassociation of cesium atoms at temperature T=54 from the continuum to bound levels in the external well of the
potential. We study how the modification of the pulse
characteristics (carrier frequency, duration, linear chirp rate and intensity)
can enhance the number of photoassociated molecules and suggest ways of
optimizing the production of stable molecules.Comment: 40 pages, 12 figures, submitted to Eur. Phys. J.
The ‘activist identity’ and activism across domains:A multiple identities analysis
Two correlational studies of activists examined the association between belonging to community organizations or groups and sustained activism within a particular domain. In Study 1 (N = 45) larger activist networks, controlling for activist identification and greater political knowledge, were associated with stronger activism intentions. In Study 2 (N = 155), larger Time 1 peace activism social networks were associated with more Time 2 peace activism and, via Time 2 activism, with sustained activism at Time 3. In contrast, Time 1 nationalist and party political identities were inhibiting factors of peace activism at Time 2, and indirectly at Time 3. In addition, larger peace activism networks at Time 1 were associated with greater international human rights activism and Christian activism at Time 3, but not as consistently with other forms of cross-domain activism. The possible organizing principles for these interrelationships are discussed
Characterization of the HeCo mutant mouse: a new model of subcortical band heterotopia associated with seizures and behavioral deficits.
In human, neuronal migration disorders are commonly associated with developmental delay, mental retardation, and epilepsy. We describe here a new mouse mutant that develops a heterotopic cortex (HeCo) lying in the dorsolateral hemispheric region, between the homotopic cortex (HoCo) and subcortical white matter. Cross-breeding demonstrated an autosomal recessive transmission. Birthdating studies and immunochemistry for layer-specific markers revealed that HeCo formation was due to a transit problem in the intermediate zone affecting both radially and tangentially migrating neurons. The scaffold of radial glial fibers, as well as the expression of doublecortin is not altered in the mutant. Neurons within the HeCo are generated at a late embryonic age (E18) and the superficial layers of the HoCo have a correspondingly lower cell density and layer thickness. Parvalbumin immunohistochemistry showed the presence of gamma-aminobutyric acidergic cells in the HeCo and the mutant mice have a lowered threshold for the induction of epileptic seizures. The mutant showed a developmental delay but, in contrast, memory function was relatively spared. Therefore, this unique mouse model resembles subcortical band heterotopia observed in human. This model represents a new and rare tool to better understand cortical development and to investigate future therapeutic strategies for refractory epilepsy
Predictors of mortality following emergency open colectomy for ischemic colitis: A single-center experience
Background: Ischemic colitis (IC) is a severe emergency in gastrointestinal surgery. The aim of the present study was to identify the predictors of postoperative mortality after emergent open colectomy for IC treatment. Additionally, we compared postoperative outcomes of patients undergoing emergent colectomy due to aortic surgery-related IC (AS-IC group) vs. other IC etiologies (Other-IC group). Methods: We analyzed records of consecutive patients who underwent emergency open colectomy for IC between 2008 and 2019. Logistic regression analysis was performed to identify clinical and operative parameters associated with postoperative mortality. The AS-IC and Other-IC groups were compared for mortality, morbidity, ICU stay, hospital stay, and survival. Results: During the study period, 94 patients (mean age, 67.4 ± 13.7 years) underwent emergent open colectomy for IC. In the majority of cases, IC involved the entire colon (53.2%) and vasopressor agents were required preoperatively (63.8%) and/or intraoperatively (78.8%). Thirty-four patients underwent surgery due to AS-IC, whereas 60 due to Other-IC causes. In the AS-IC group, 9 patients had undergone endovascular aortic repair and 25 open aortic surgery; 61.8% of patients needed aortic surgery for ruptured abdominal aortic aneurism (AAA). Overall, 66 patients (70.2%) died within 90 days from surgery. The AS-IC and Other-IC groups showed similar operative outcomes and postoperative complication rates. However, the duration of the ICU stay (19 days vs. 11 days; p = 0.003) and of the total hospital stay (22 days vs. 16 days; p = 0.016) was significantly longer for the AS-IC group than for the Other-IC group. The rate of intestinal continuity restoration at 1 year after surgery was higher for the Other-IC group than for the AS-IC group (58.8% vs. 22.2%; p = 0.05). In the multivariate model, preoperative increased lactate levels, a delay between signs/symptoms' onset and surgery > 12 h, and the occurrence of postoperative acute kidney injury were statistically associated with postoperative mortality. Neither IC etiology (aortic surgery vs. other etiology) nor ruptured AAA was associated with postoperative mortality. Conclusion: Emergency open colectomy for IC is associated with high postoperative mortality, which appears to be unrelated to the IC etiology. Preoperative lactate levels, > 12-h delay to surgery, and postoperative acute kidney injury are independent predictors of postoperative mortality
Optimal trapping wavelengths of Cs molecules in an optical lattice
The present paper aims at finding optimal parameters for trapping of Cs
molecules in optical lattices, with the perspective of creating a quantum
degenerate gas of ground-state molecules. We have calculated dynamic
polarizabilities of Cs molecules subject to an oscillating electric field,
using accurate potential curves and electronic transition dipole moments. We
show that for some particular wavelengths of the optical lattice, called "magic
wavelengths", the polarizability of the ground-state molecules is equal to the
one of a Feshbach molecule. As the creation of the sample of ground-state
molecules relies on an adiabatic population transfer from weakly-bound
molecules created on a Feshbach resonance, such a coincidence ensures that both
the initial and final states are favorably trapped by the lattice light,
allowing optimized transfer in agreement with the experimental observation
- …