5,404 research outputs found

    Effects of state dependent correlations on nucleon density and momentum distributions

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    The proton momentum and density distributions of closed shell nuclei are calculated within a model treating short--range correlations up to first order in the cluster expansion. The validity of the model is verified by comparing the results obtained with purely scalar correlations with those produced by finite nuclei Fermi Hypernetted Chain calculations. State dependent correlations are used to calculate momentum and density distributions of 12C, 16O, 40Ca, and 48Ca, and the effects of their tensor components are studied.Comment: 16 pages, latex, 8 figures, accepted for publication in Phys. Rev.

    Fundamentals of microcrack nucleation mechanics

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    A foundation for ultrasonic evaluation of microcrack nucleation mechanics is identified in order to establish a basis for correlations between plane strain fracture toughness and ultrasonic factors through the interaction of elastic waves with material microstructures. Since microcracking is the origin of (brittle) fracture, it is appropriate to consider the role of stress waves in the dynamics of microcracking. Therefore, the following topics are discussed: (1) microstress distributions with typical microstructural defects located in the stress field; (2) elastic wave scattering from various idealized defects; and (3) dynamic effective-properties of media with randomly distributed inhomogeneities

    Structural evolution drives diversification of the large LRR-RLK gene family

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    Cells are continuously exposed to chemical signals that they must discriminate between and respond to appropriately. In embryophytes, the leucine‐rich repeat receptor‐like kinases (LRR‐RLKs) are signal receptors critical in development and defense. LRR‐RLKs have diversified to hundreds of genes in many plant genomes. Although intensively studied, a well‐resolved LRR‐RLK gene tree has remained elusive. To resolve the LRR‐RLK gene tree, we developed an improved gene discovery method based on iterative hidden Markov model searching and phylogenetic inference. We used this method to infer complete gene trees for each of the LRR‐RLK subclades and reconstructed the deepest nodes of the full gene family. We discovered that the LRR‐RLK gene family is even larger than previously thought, and that protein domain gains and losses are prevalent. These structural modifications, some of which likely predate embryophyte diversification, led to misclassification of some LRR‐RLK variants as members of other gene families. Our work corrects this misclassification. Our results reveal ongoing structural evolution generating novel LRR‐RLK genes. These new genes are raw material for the diversification of signaling in development and defense. Our methods also enable phylogenetic reconstruction in any large gene family

    He Told Me So / music by J. W. Schoff; words by Emily T. Charles

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    Cover: text reads Dedicated to Miss Katie N. Scott; Publisher: John F. Ellis and Co. (Washington D.C.)https://egrove.olemiss.edu/sharris_a/1016/thumbnail.jp

    A model for two-proton emission induced by electron scattering

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    A model to study two-proton emission processes induced by electron scattering is developed. The process is induced by one-body electromagnetic operators acting together with short-range correlations, and by two-body Δ\Delta currents. The model includes all the diagrams containing a single correlation function. A test of the sensitivity of the model to the various theoretical inputs is done. An investigation of the relevance of the Δ\Delta currents is done by changing the final state angular momentum, excitation energy and momentum transfer. The sensitivity of the cross section to the details of the correlation function is studied by using realistic and schematic correlations. Results for 12^{12}C, 16^{16}O and 40^{40}Ca nuclei are presented.Comment: 30 pages, 18 figures, 3 table

    Interfering Doorway States and Giant Resonances. I: Resonance Spectrum and Multipole Strengths

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    A phenomenological schematic model of multipole giant resonances (GR) is considered which treats the external interaction via common decay channels on the same footing as the coherent part of the internal residual interaction. The damping due to the coupling to the sea of complicated states is neglected. As a result, the formation of GR is governed by the interplay and competition of two kinds of collectivity, the internal and the external one. The mixing of the doorway components of a GR due to the external interaction influences significantly their multipole strengths, widths and positions in energy. In particular, a narrow resonance state with an appreciable multipole strength is formed when the doorway components strongly overlap.Comment: 20 pages, LaTeX, 3 ps-figures, to appear in PRC (July 1997

    Evolution favors protein mutational robustness in sufficiently large populations

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    BACKGROUND: An important question is whether evolution favors properties such as mutational robustness or evolvability that do not directly benefit any individual, but can influence the course of future evolution. Functionally similar proteins can differ substantially in their robustness to mutations and capacity to evolve new functions, but it has remained unclear whether any of these differences might be due to evolutionary selection for these properties. RESULTS: Here we use laboratory experiments to demonstrate that evolution favors protein mutational robustness if the evolving population is sufficiently large. We neutrally evolve cytochrome P450 proteins under identical selection pressures and mutation rates in populations of different sizes, and show that proteins from the larger and thus more polymorphic population tend towards higher mutational robustness. Proteins from the larger population also evolve greater stability, a biophysical property that is known to enhance both mutational robustness and evolvability. The excess mutational robustness and stability is well described by existing mathematical theories, and can be quantitatively related to the way that the proteins occupy their neutral network. CONCLUSIONS: Our work is the first experimental demonstration of the general tendency of evolution to favor mutational robustness and protein stability in highly polymorphic populations. We suggest that this phenomenon may contribute to the mutational robustness and evolvability of viruses and bacteria that exist in large populations
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