Patterns of behavior in lodgings exposed to traffic noise

Threshold values for public services interferent on the attenuation to noise nuisance were defined. Daily life at home was described and collected on the use of residences, the effects of noise on health and sleep, and the incidence of running away from home. A correlation was made with the equipment and noise insulation of homes. It is shown that there are behavior patterns in the modification of considerable manner in the way of life for people who live in apartments and in individual houses, above 66 dB during daytime

Did high Neo-Tethys subduction rates contribute to early Cenozoic warming?

International audienceThe 58–51 Ma interval was characterized by a long-term increase of global temperatures (+4 to +6 • C) up to the Early Eocene Climate Optimum (EECO, 52.9– 50.7 Ma), the warmest interval of the Cenozoic. It was recently suggested that sustained high atmospheric pCO 2 , controlling warm early Cenozoic climate, may have been released during Neo-Tethys closure through the subduction of large amounts of pelagic carbonates and their recycling as CO 2 at arc volcanoes. To analyze the impact of Neo-Tethys closure on early Cenozoic warming, we have mod-eled the volume of subducted sediments and the amount of CO 2 emitted along the northern Tethys margin. The impact of calculated CO 2 fluxes on global temperature during the early Cenozoic have then been tested using a climate carbon cycle model (GEOCLIM). We show that CO 2 production may have reached up to 1.55 × 10 18 mol Ma −1 specifically during the EECO, ∼ 4 to 37 % higher that the modern global volcanic CO 2 output, owing to a dramatic India-Asia plate convergence increase. The subduction of thick Greater Indian continental margin carbonate sediments at ∼ 55–50 Ma may also have led to additional CO 2 production of 3.35 × 10 18 mol Ma −1 during the EECO, making a total of 85 % of the global volcanic CO 2 outgassed. However , climate modeling demonstrates that timing of maximum CO 2 release only partially fits with the EECO, and that corresponding maximum pCO 2 values (750 ppm) and surface warming (+2 • C) do not reach values inferred from geo-chemical proxies, a result consistent with conclusions arising from modeling based on other published CO 2 fluxes. These results demonstrate that CO 2 derived from decarbonation of Neo-Tethyan lithosphere may have possibly contributed to, but certainly cannot account alone for early Cenozoic warming. Other commonly cited sources of excess CO 2 such as enhanced igneous province volcanism also appear to be up to 1 order of magnitude below fluxes required by the model to fit with proxy data of pCO 2 and temperature at that time. An alternate explanation may be that CO 2 consumption, a key parameter of the long-term atmospheric pCO 2 balance, may have been lower than suggested by modeling. These results call for a better calibration of early Cenozoic weathering rates

Divergent Routing of Positive and Negative Information from the Amygdala during Memory Retrieval

Although the basolateral amygdala (BLA) is known to play a critical role in the formation of memories of both positive and negative valence, the coding and routing of valence-related information is poorly understood. Here, we recorded BLA neurons during the retrieval of associative memories and used optogenetic-mediated phototagging to identify populations of neurons that synapse in the nucleus accumbens (NAc), the central amygdala (CeA), or ventral hippocampus (vHPC). We found that despite heterogeneous neural responses within each population, the proportions of BLA-NAc neurons excited by reward predictive cues and of BLA-CeA neurons excited by aversion predictive cues were higher than within the entire BLA. Although the BLA-vHPC projection is known to drive behaviors of innate negative valence, these neurons did not preferentially code for learned negative valence. Together, these findings suggest that valence encoding in the BLA is at least partially mediated via divergent activity of anatomically defined neural populations.National Institute of Mental Health (U.S.) (Grant R01-MH102441-01)National Institutes of Health (U.S.) (Grant DP2-DK-102256-01

Quantification of the Total Amount of Artemisinin in Leaf Samples by Thin Layer Chromatography: FH – HES

Artemisinin is a natural molecule highly active against malaria. At present, the extraction of this molecule from the leaves of Artemisia annua L. remains the only viable method to produce cheaply large quantities of artemisinin. Agronomic research on this plant species aims to improve agricultural yields, to decrease production costs and to ensure a steady global supply of artemisinin. These research activities require an easy, rapid, low cost, and reliable analytical technique to quantify the artemisinin content in the leaves. Thin layer chromatography (TLC) methods to quantify this molecule have already been published. However, this method does not allow the quantification of the total artemisinin content in the leaves. In order to validate the TLC method, results obtained with this method were related to results for the same samples obtained by accelerated solvent extraction and high pressure liquid chromatography with an evaporative light scattering detector (ASE-HPLC-ELSD). Using the Nernst partition law, a corrective factor of 1.21 is suggested to enable information about the true total amount of artemisinin in leaf samples to be obtained within a range of 0.25 to 3%. In conclusion, this study proposes for the first time a corrective factor in order to quantify the total artemisinin content of A. annua leaves with TLC

Pharmacologie de l’intestin du cheval. Action de l’adrénaline sur la motricité du duodénum de cheval in vivo

Simonnet Henri, Le Bars Henri, Stassive W., Chapeville F. Pharmacologie de l’intestin du cheval. Action de l’adrénaline sur la motricité du duodénum de cheval in vivo.. In: Bulletin de l'Académie Vétérinaire de France tome 105 n°3, 1952. pp. 75-82

Multiple Redox Modes in the Reversible Lithiation of High-Capacity, Peierls-Distorted Vanadium Sulfide.

This is the author accepted manuscript. The final version is available from ACS via http://dx.doi.org/10.1021/jacs.5b03395Vanadium sulfide VS4 in the patronite mineral structure is a linear chain compound comprising vanadium atoms coordinated by disulfide anions [S2](2-). (51)V NMR shows that the material, despite having V formally in the d(1) configuration, is diamagnetic, suggesting potential dimerization through metal-metal bonding associated with a Peierls distortion of the linear chains. This is supported by density functional calculations, and is also consistent with the observed alternation in V-V distances of 2.8 and 3.2 Å along the chains. Partial lithiation results in reduction of the disulfide ions to sulfide S(2-), via an internal redox process whereby an electron from V(4+) is transferred to [S2](2-) resulting in oxidation of V(4+) to V(5+) and reduction of the [S2](2-) to S(2-) to form Li3VS4 containing tetrahedral [VS4](3-) anions. On further lithiation this is followed by reduction of the V(5+) in Li3VS4 to form Li3+xVS4 (x = 0.5-1), a mixed valent V(4+)/V(5+) compound. Eventually reduction to Li2S plus elemental V occurs. Despite the complex redox processes involving both the cation and the anion occurring in this material, the system is found to be partially reversible between 0 and 3 V. The unusual redox processes in this system are elucidated using a suite of short-range characterization tools including (51)V nuclear magnetic resonance spectroscopy (NMR), S K-edge X-ray absorption near edge spectroscopy (XANES), and pair distribution function (PDF) analysis of X-ray data.SB acknowledges Schlumberger Stichting Fund and European Research Council (EU ERC) for funding. JC thanks BK21 plus project of Korea. We thank Phoebe Allan and Andrew J. Morris, University of Cambridge, for useful discussions. We also thank Trudy Bolin and Tianpin Wu of Beamline 9-BM, Argonne National Laboratory for help with XANES measurements. The DFT calculations were performed at the UCSB Center for Scientific Computing at UC Santa Barbara, supported by the California Nanosystems Institute (NSF CNS-0960316), Hewlett-Packard, and the Materials Research Laboratory (DMR-1121053). This research used resources of the Advanced Photon Source, a U.S. Department of Energy (DOE) Office of Science User Facility operated for the DOE Office of Science by Argonne National Laboratory under Contract No. DE-AC02-06CH11357

Current genetic admixture between relictual populations might enhance the recovery of an elusive carnivore

The present study investigated the natural recovery of the Eurasian otter (Lutra lutra) in France. The otter was widely distributed in France at the dawn of the 20th century, but then its range considerably shrank and became highly fragmented until the early 1970s, just before it was legally protected. However, for more than 25 years, the otter has been reconquering several parts of its original range and is now considered to be in expansion in France. We investigated the genetic differentiation and diversity of several populations from western and central France and northern Spain to gain insight into the recolonisation dynamics of this elusive species. The present study, based on the use of 14 microsatellite markers, revealed that otter populations seem to be split into five distinct groups. The distribution of samples in those five clusters was closely correlated with suspected refugia where the otter probably survived during the 20th century. Admixture was observed between genetic lineages, possibly enhancing their genetic diversity and thus increasing the recolonisation dynamics of these populations. This phenomenon resembles the genetic pattern noted in many invasive exotic species derived from multiple sources and introduction events. Finally, a demographic approach revealed the probable link between historical human pressure and otter population fragmentation patterns