74 research outputs found

    Using entropy to maximize the usefulness of data collection

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    This paper presents a generic methodology for measurement system configuration when the goal is to identify behaviour models that reasonably explain observations. For such tasks, the best measurement system provides maximum separation between candidate models. In this work, the degree of separation between models is measured using Shannon’s Entropy Function. The location and type of measurement devices are chosen such that the entropy of candidate models is greatest. This methodology is tested on a laboratory structure and, to demonstrate generality, an existing fresh water supply network in a city in Switzerland. In both cases, the methodology suggests an appropriate set of sensors for identifying the state of the system

    Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients

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    FDI and regional development policy

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    The transformations in the worldwide division of labour brought about by globalisation and technological change have shown an unintended negative effect, particularly evident in advanced economic systems: uneven spatial distribution of wealth and rising within-country inequality. Although the latter has featured prominently in recent academic and policy debates, in this paper we argue that the relevance of connectivity (here proxied by foreign capital investments, FDI) for regional economic development is still underestimated and suffers from a nation-biased perspective. As a consequence, the relationship between the spatial inequality spurred by the global division of labour and the changes in the structural advantages of regions remains to be fully understood in its implications for economic growth, territorial resilience and industrial policy. Furthermore, even though connectivity entails bi-directional links – i.e. with regions being simultaneously receivers and senders – attractiveness to foreign capital has long been at the centre of policy attention whilst internationalisation through investment abroad has been disregarded, and sometimes purposely ignored, in regional development policy agendas. We use three broad-brushed European case-studies to discuss some guiding principles for a place-sensitive regional policy eager to integrate the connectivity dimension in pursuing local economic development and territorial equity

    Developmental changes in the responsiveness to ecdysterone of chromosome region I-18C of Chironomus tentans.

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    The presence of nascent RNA in chromosome region I-18C was revealed by the method of induced hybrid formation (IEH) and by use of anti-RNA: DNA antibodies. IEH signals were quantitated, and used as a measure of transcriptional activity in the region. The expansion of the I-18C region was also determined and used as an indication of local chromatin decondensation. Chironomus tentans larvae may undergo oligopause or they may develop subitaneously. It was found that the course of basal activity in I-18C differs substantially in these two modes of development. Most interestingly they also differ in activation of I-18C in response to in vitro ecdysterone treatment. Changes in hormonal responsiveness of I-18C parallel changes in the preexisting state of I-18C decondensation. Oligopause stage 5 animals, being most refractory in this respect, exhibit the most condensed I-18C chromosome region

    Trade and towns: Heterogeneous adjustment to a border shock

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    We study the effects of changes in trade openness on wages and employment across towns of different sizes, using Austrian regional data and the fall of the Iron Curtain as a quasi-experimental setting. We find improved access to foreign markets to boost both employment and nominal wages in border regions, but large towns tend to have larger wage responses and smaller employment responses than small towns. These adjustment patterns are consistent with a multi-region model featuring labor supply elasticities that vary with town size. The implied differential border-town welfare gains are related non-monotonically to town size, peaking at a population level of about 150,000
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