226 research outputs found
Manufacturing Consent Over Statehood Recognition: The New York Times Coverage Of Palestine And Kosovo Statehood Recognition
The mainstream media in democratic societies play a key role in shaping the
audience perceptions, especially in relation to international affairs. They have the
ability to “manufacture” the public consent over the state’s foreign policies.
Recognizing or opposing an emerging state is deemed one significant policy at the
agenda of governments’ diplomatic foreign affairs. Still, the international recognition
by superpower states (i.e. the United States) is influential. The U.S. foreign policy of
Palestine and Kosovo statehood recognition constitutes a clear example of the
administration’s double standards. Although both states fulfil the minimum criteria
of statehood, the U.S. opposes the recognition of the State of Palestine and supports
Kosovo’s one. This research examines how the New York Times (NYT)—as a
dominant U.S. media—manufactures consent pertaining to the U.S. foreign policy of
statehood recognition. The current research employs the Propaganda Model of
Herman and Chomsky (1988) as a theoretical thrust. It examines the occurrence of
both reporting and ideological biases. Subsequently, three variables are investigated:
the degree of reliance on U.S. official news sources; the degree of attention paid to
issues under scrutiny; and the representation of the social actors and practices within
the related discourse. Both quantitative content analysis and Critical Discourse
Analysis (CDA) are adopted. The findings demonstrate that the NYT has offered a
fake balance of voices within its related coverage
Selection Of A Novel Aptamer Against Vitronectin Using Capillary Electrophoresis And Next Generation Sequencing
Breast cancer (BC) results in ≃40,000 deaths each year in the United States and even among survivors treatment of the disease may have devastating consequences, including increased risk for heart disease and cognitive impairment resulting from the toxic effects of chemotherapy. Aptamer-mediated drug delivery can contribute to improved treatment outcomes through the selective delivery of chemotherapy to BC cells, provided suitable cancer-specific antigens can be identified. We report here the use of capillary electrophoresis in conjunction with next generation sequencing to develop the first vitronectin (VN) binding aptamer (VBA-01; Kd 405 nmol/l, the first aptamer to vitronectin (VN; Kd = 405 nmol/l), a protein that plays an important role in wound healing and that is present at elevated levels in BC tissue and in the blood of BC patients relative to the corresponding nonmalignant tissues. We used VBA-01 to develop DVBA-01, a dimeric aptamer complex, and conjugated doxorubicin (Dox) to DVBA-01 (7:1 ratio) using pH-sensitive, covalent linkages. Dox conjugation enhanced the thermal stability of the complex (60.2 versus 46.5°C) and did not decrease affinity for the VN target. The resulting DVBA-01-Dox complex displayed increased cytotoxicity to MDA-MB-231 BC cells that were cultured on plasticware coated with VN (1.8 × 10⁻⁶mol/l) relative to uncoated plates (2.4 × 10⁻⁶ mol/l), or plates coated with the related protein fibronectin (2.1 × 10⁻⁶ mol/l). The VBA-01 aptamer was evaluated for binding to human BC tissue using immunohistochemistry and displayed tissue specific binding and apparent association with BC cells. In contrast, a monoclonal antibody that preferentially binds to multimeric VN primarily stained extracellular matrix and vessel walls of BC tissue. Our results indicate a strong potential for using VN-targeting aptamers to improve drug delivery to treat BC
Triangular Ring Resonator: Direct measurement of the parity-odd parameters of the photon sector of SME
We introduce the the Triangular Ring (TR) resonator. We show that the
difference between the clockwise and anti-clockwise resonant frequencies of a
vacuum TR resonator is sensitive to the birefringence parity-odd parameters of
the photon's sector of the minimal Standard Model Extension (mSME): the
Standard Model plus all the perturbative parameters encoding the break the
Lorentz symmetry. We report that utilizing the current technology allows for
direct measurement of these parameters with a sensitivity of the parity even
ones and improves the best current resonator bounds by couple of orders of
magnitudes.
We note that designing an optical table that rotates perpendicular to the
gravitational equipotential surface (geoid) allows for direct measurement of
the constancy of the light speed at the vicinity of the earth in all directions
in particular perpendicular to the geoid. If this table could achieve the
precision of the ordinary tables, then it would improve the GPS bounds on the
constancy of the light speed perpendicular to geoid by about eight orders of
magnitude.Comment: ref. added, minor corrections, matches the published versio
The effect of palm oil fuel clinker powder and cockleshell powder as cement replacement on durability properties of the concrete mortar
The concepts of eco-friendly building are getting more attention today. The standard materials of concrete that used such as cement and aggregate are not totally environmentally friendly. Thus, many materials from natural sources can be an alternative to the realization of the green building concept. As a result, many researchers have devoted their attention towards identifying eco-friendlier substitutions to be used in concrete. This study was conducted to investigate the efficiency of two different types of waste materials which are palm oil clinker (POC) and cockle shell (CS) as partial replacement of cement on durability aspects. The POC and CS materials were ground to achieve a small particle size to fit with the concrete mix as cement replacement. The replacement of cement was at different levels (10% and 20%). Six mix proportions were made with different percentage of palm oil clinker powder POCP and cockle shell powder CSP. The specimens were cured by immersing in water for 7 and 28 days. The tests that were conducted were acid resistance test and water absorption test. Therefore, the experiment result showed that the POC had a negative impact to the concrete in both tests while the CSP proved it is resistance to acid
Recuperação de área degradada com sistema agroflorestal no Vale do Rio Doce, Minas Gerais.
O Vale do Rio Doce, MG, apresenta um histórico de ocupação e uso do solo que favorece a degradação ambiental, em que predominam pastagens sob o uso constante de queimadas. Os sistemas agroflorestais têm se mostrado eficientes na recuperação de áreas degradadas. Neste estudo foram avaliados os efeitos de um sistema agroflorestal na recuperação do solo em área degradada por pastagem na comunidade de Ilha Funda,Município de Periquito, Minas Gerais. A implantação do sistema se deu em 1994 e está sendo conduzido segundo os princípios agroecológicos, potencializando a regeneração natural e a sucessão de espécies. Em 1998, foram coletadas amostras de solo na área em recuperação e em duas áreas adjacentes: uma área degradada, que se encontrava em condições semelhantes às da área em recuperação no início do processo, e outra ocupada por pastagem. Foram determinados atributos químicos do solo e realizada a caracterização da matéria orgânica. O solo da área em recuperação com sistema agroflorestal mostrou-se em melhores condições do que o solo sob pastagem e o da área degradada, apresentando maior dinâmica do carbono orgânico e maior disponibilidade de nutrientes. Embora o teor de carbono orgânico total apresentado pelo solo sob pastagem tenha sido maior que nas demais condições avaliadas, o solo do sistema agroflorestal já está se igualando ao da pastagem no acúmulo das formas mais estáveis de carbono e apresentando maior dinâmica das frações orgânicas menos estáveis. Este estudo comprovou a eficiência dos sistemas agroflorestais, conduzidos segundo os princípios agroecológicos, na recuperação de áreas degradadas
Speckle Tracking Echocardiography for the Assessment of the Athlete's Heart: Is It Ready for Daily Practice?
PURPOSE OF REVIEW: To describe the use of speckle tracking echocardiography (STE) in the biventricular assessment of athletes' heart (AH). Can STE aid differential diagnosis during pre-participation cardiac screening (PCS) of athletes? RECENT FINDINGS: Data from recent patient, population and athlete studies suggest potential discriminatory value of STE, alongside standard echocardiographic measurements, in the early detection of clinically relevant systolic dysfunction. STE can also contribute to subsequent prognosis and risk stratification. Despite some heterogeneity in STE data in athletes, left ventricular global longitudinal strain (GLS) and right ventricular longitudinal strain (RV ɛ) indices can add to differential diagnostic protocols in PCS. STE should be used in addition to standard echocardiographic tools and be conducted by an experienced operator with significant knowledge of the AH. Other indices, including left ventricular circumferential strain and twist, may provide insight, but further research in clinical and athletic populations is warranted. This review also raises the potential role for STE measures performed during exercise as well as in serial follow-up as a method to improve diagnostic yield
Modelling Temperature Variation of Mushroom Growing Hall Using Artificial Neural Networks
The recent developments of computer and electronic systems have made the use
of intelligent systems for the automation of agricultural industries. In this
study, the temperature variation of the mushroom growing room was modeled by
multi-layered perceptron and radial basis function networks based on
independent parameters including ambient temperature, water temperature, fresh
air and circulation air dampers, and water tap. According to the obtained
results from the networks, the best network for MLP was in the second
repetition with 12 neurons in the hidden layer and in 20 neurons in the hidden
layer for radial basis function network. The obtained results from comparative
parameters for two networks showed the highest correlation coefficient (0.966),
the lowest root mean square error (RMSE) (0.787) and the lowest mean absolute
error (MAE) (0.02746) for radial basis function. Therefore, the neural network
with radial basis function was selected as a predictor of the behavior of the
system for the temperature of mushroom growing halls controlling system
Comparative survey of native species culture (Penaeus semisulcatus and Fenneropenaeus indicus) with non-native species (Litopenaeus vannamei) in Hele site of Bushehr province
The culture of three species green tiger prown (Penaeus semisulcatus) ,white leg shrimp (Litopenaeus vannamei) and Indian white shrimp (Fenneropenaeus indicus) were grown in 7 ponds (0.4 and 0.25 hectare) for 110 days at a stocking density of 25 shrimp/m2 on Hele Research Station. The average of temperature and salinity was 30 degrees centigrade and 46-48 ppt .At the end of the culture mean weights of L.vannamei 18.68±2.6 was higer than the P.semisucatus 7.77±1.49 and F.indicus 14.66 ±2.1 also results demonstrated that there was a significant relation (P<0.05) between mean weight. Final yield were 3114, 1983 and 848 Kg for L.vannamei, F.indicus and P.semisucatus.The FCR was better for L.vannamei (1.28) than F.indicus (1.48) and P.semisucatus (2.15)
The outcome of ultrasound-guided insertion of central hemodialysis catheter
Objective: To point out our experience and assess the efficacy and safety of real-time ultrasound-guided central internal jugular vein (IJV) catheterization in the treatment of hemodialysis patients. Methods: This retrospective study comprised 150 patients with end-stage renal disease (ESRD) who had real-time ultrasonography (US)-guided IJV HD catheters placed in our hospital between March 2019 and March 2021. Patients were examined for their demographic data, etiology, site of catheter insertion, type (acute or chronic) of renal failure, technical success, operative time, number of needle punctures, and procedure-related complications. Patients who have had multiple catheter insertions, prior catheterization challenges, poor compliance, obesity, bony deformity, and coagulation disorders were considered at high-operative risk. Results: All patients experienced technical success. In terms of patient clinical features, an insignificant difference was observed between the normal and high-risk groups (p-value > 0.05). Of the 150 catheters, 62 (41.3%) were placed in high-risk patients. The first-attempt success rate was 89.8% for the normal group and 72.5% for the high-risk group (p = 0.006). IJV cannulation took less time in the normal-risk group compared to the highrisk group (21.2 ± 0.09) minutes vs (35.4 ± 0.11) minutes, (p < 0.001). There were no serious complications. During the placing of the catheter in the internal jugular vein, four patients (6.4%) experienced arterial puncture in the high-risk group. Two participants in each group got a small neck hematoma. One patient developed a pneumothorax in the high-risk group, which was managed with an intercostal chest tube insertion. Conclusions: Even in the high-risk group, the real-time US-guided placement of a central catheter into the IJV is associated with a low complication rate and a high success rate. Even under US guidance, experience lowers complication rates. Real-time USguided is recommended to be used routinely during central venous catheter insertion
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