Structural effects of steel reinforcement corrosion on statically indeterminate reinforced concrete members

The final publication is available at Springer via http://dx.doi.org/10.1617/s11527-016-0836-2Steel corrosion in reinforced concrete structures produces loss of reinforcement area and damage in the surrounding concrete. As a consequence, increases in deflections, crack widths and stresses may take place, as well as a reduction of the bearing capacity, which depends on the structural scheme and redundancy. In this paper an experimental study of twelve statically indeterminate beams subjected to different levels of forced reinforcement corrosion is presented. Different sustained loads were applied during the corrosion phase to assess their influence on the effects of corrosion. An important increase in deflections was registered in all corroded beams, especially in those subject to higher load levels. It was also found that the rate of corrosion was affected by the load level. Internal forces redistributions due to induced damage were measured. Finally, the experimental results were compared with those predicted by a non-linear time-dependent segmental analysis model developed by the authors, obtaining in general good agreement.Peer ReviewedPostprint (author's final draft

Influence of a Compact Fe2O3 Layer on the Photovoltaic Performance of Perovskite-Based Solar Cells

[EN] In this study, uniform and dense iron oxide ¿-Fe2O3 thin films were used as an electron-transport layer (ETL) in CH3NH3PbI3-based perovskite solar cells (PSCs), replacing the Titanium dioxide (TiO2) ETL conventionally used in planar heterojunction perovskite solar cells. The ¿-Fe2O3 films were synthesized using an electrodeposition method for the blocking layer and a hydrothermal method for the overlaying layer, while 2,2¿,7,7¿-tetrakis (N, N¿-di-p-methoxyphenylamine)-9,9¿ spirobifluorene (spiro-OMeTAD) was employed as a hole conductor in the solar cells. Based on the above synthesized ¿-Fe2O3 films the photovoltaic performance of the PSCs was studied. The ¿-Fe2O3 layers were found to have a significant impact on the photovoltaic conversion efficiency (PCE) of the PSCs. This was attributed to an efficient charge separation and transport due to a better coverage of the perovskite on the ¿-Fe2O3 films. As a result, the PCE measured under standard solar conditions (AM 1.5G, 100 mW cm¿2) reached 5.7%.This work was supported by the Ministry of High Education and Scientific Research, Tunisia and Ministerio de Economia y Competitividad (ENE2013-46624-C4-4-R) and Generalitatvalenciana (Prometeus 2014/044).Bouhjar, F.; Mollar García, MA.; Ullah, S.; Marí, B.; Bessais, B. (2018). Influence of a Compact Fe2O3 Layer on the Photovoltaic Performance of Perovskite-Based Solar Cells. Journal of The Electrochemical Society. 165(2):30-38. https://doi.org/10.1149/2.1131802jesS3038165

Ultimate capacity of corroded statically indeterminate reinforced concrete members

The corrosion of steel reinforcement is commonly believed to be the primary cause of structural deterioration of reinforced concrete (RC) structures; as a result of this deterioration, a RC structure can incur a considerable reduction in structural serviceability and safety. Because of their inherent redundancy, statically indeterminate structures develop resistant mechanisms that can potentially assist in delaying the collapse of severely damaged RC structures. In order to experimentally demonstrate these resistant mechanisms, four groups of three two-span continuous RC beam members each were deteriorated using induced corrosion methods and tested to failure under monotonic loads. For control, one group of three RC beams was left uncorroded and similarly load tested. All the RC beam specimens subjected to corrosion demonstrated a significant reduction (a maximum reduction of 55% as compared to the uncorroded control group) of their ultimate capacity. The presence of corrosion induced a transition from flexural failure to anchorage failure in some specimens; despite the induced damage some redistributed structural capacity was observed. Modelling of deterioration effects by the inclusion of different aspects of corrosion was also conducted. Three-dimensional (3D) Finite-Element Method (FEM) models were developed to assess the variation in the mechanical properties of the corroded steel and the reduction in the bond interaction between concrete and steel due to the corrosion of the steel reinforcement. In general, the current 3D FEM models demonstrated a good agreement with the experimental data; however, 3D FEM models that exhibit greater sophistication are necessary to better describe the failure mode of some RC beam specimens when they are associated with local effects.Peer ReviewedPostprint (published version

Communication, development, and social change in Spain: A field between institutionalization and implosion

This paper renders an account of the rapid institutionalization of the academic field of Communication for Development and Social Change (CDCS) in Spain in recent years following a period of neglect and marginalization. The ongoing expansion of the field of CDSC in the Spanish context is understood as a process of implosion, i.e. a collapse inwards, which results from the inconsistencies and weaknesses of fast and late institutionalization. The methodological approach for this inquiry is a documental review of both academic literature and research and institutional reports produced in Spain between 1980 and 2010. Based on this review, the paper contrasts the trajectory of the field in Spain with the debates at the international level, establishing relevant continuities and differences.This article is part of the Research Project (Ministry of Economy and Competitiveness, Spain) CSO2014-52005-R titled ‘Evaluation and Monitoring of Communication for Development and Social Change in Spain: design of indicators to measure its social impact’ (2015–2017)17 página

Gender differences in the plasma concentration of the GAS6-TAM system in COVID-19 patients

Resumen del trabajo presentado en el 4th European Congress on Thrombosis and Haemostasis, celebrado en Gante (Bélgica), los días 14 y 15 de octubre de 2021Background: SARS-CoV-2 induces an immune response with potentially harmful effects for the patient due to an uncontrolled release of inflammatory factors, specially at the capillary wall. The vitamin K-dependent plasma protein GAS6 and the TAM (TYRO3, AXL, and MERTK) receptors play a relevant role among restorative mechanisms that counterbalance pro-inflammatory responses at the endothelial interface. Aims: To study the influence of gender on the effects of SARS-CoV-2 infection in the GAS6/TAM system, as reflected by plasma concentration at patient admittance at the emergency ward. Methods: The plasma content of GAS6, AXL, and MERTK was analyzed in a first group of 132 patients, 68 females and 64 males consecutively admitted to the emergency ward during the first peak of COVID-19. A confirmatory group was studied from the second wave of contagions. An analysis of gender differences in relation to the GAS6/TAM concentrations in plasma was performed on this population. Results: In accordance with recently published GAS6 levels, significantly higher in the SARS-CoV-2 positive than in negative patients, increased progressively with the severity of the disease in SARS-CoV-2 positive individual irrespective of the gender of the patient. In contrast, while soluble AXL exhibited higher plasma concentration in deceased patients and no significant differences were observed in MERTK concentration, differential gender analysis suggest differences in soluble TAM receptors. While a COVID-19 related increase in sAXL was observed in men, this was not the case in women. Oppositely, MERTK differences due to COVID-19 infection were only significant in women. Summary/Conclusion: GAS6-TAM system of ligands and receptors is implicated in the immune response to SARS-CoV-2 in patients from both genders. Plasma GAS6 levels paralleled COVID-19 severity being an early marker of disease prognosis in both sexes. In contrast, soluble TAM receptors presented a gender-specific behavior. Sex-related differences in sAXL and sMERTK expression in COVID-19 patients could affect therapy efficacy deserving further investigation

Trophic niche partitioning of five skate species of genus Bathyraja in northern and central Patagonia, Argentina

Overexploitation of marine communities can lead to modifications in the structure of the food web and can force organisms like elasmobranchs to change their feeding habits. To evaluate the impact that fisheries have on food webs and on the interactions between species, it is necessary to describe and quantify the diet of the species involved and follow it through time. This study compares the diet of five skate species using the data obtained from the by-catch of the Argentine hake (Merluccius hubbsi) fishery in north and central Patagonia, Argentina. Diet composition was assessed by analysing the digestive tract contents and trophic overlapping between species of the genus Bathyraja: Bathyraja albomaculata, Bathyraja brachyurops, Bathyraja macloviana, Bathyraja magellanica and Bathyraja multispinis. A total of 184 stomachs were analysed. The diets of B. albomaculata and B. macloviana mainly comprised annelids, whereas that of B. brachyurops primarily comprised fish, including hake heads discarded by the fishery. The diets of B. magellanica and B. multispinis were largely based on crustaceans. Despite the morphological similarities and their shared preference for benthic habitats, no complete diet overlaps were found between the different species. These results suggest that these skate species have undergone a process of diet specialisation. This is a common feeding strategy that occurs to successfully eliminate competition when resources are limited, which corresponds to the conditions found in an environment being affected by the pressures of overfishing.Fil: Tschopp, Ayelen. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Centro para el Estudio de Sistemas Marinos; ArgentinaFil: Cristiani, Franco. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales y Ciencias de la Salud - Sede Puerto Madryn. Departamento de Biología y Ambiente; ArgentinaFil: Garcia, Nestor Anibal. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Centro para el Estudio de Sistemas Marinos; ArgentinaFil: Crespo, Enrique Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Centro para el Estudio de Sistemas Marinos; Argentina. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales y Ciencias de la Salud - Sede Puerto Madryn. Departamento de Biología y Ambiente; ArgentinaFil: Coscarella, Mariano Alberto. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Centro Nacional Patagónico. Centro para el Estudio de Sistemas Marinos; Argentina. Universidad Nacional de la Patagonia "San Juan Bosco". Facultad de Ciencias Naturales y Ciencias de la Salud - Sede Puerto Madryn. Departamento de Biología y Ambiente; Argentin

Identification of the PTPN22 functional variant R620W as susceptibility genetic factor for giant cell arteritis

Objective: To analyse the role of the PTPN22 and CSK genes, previously associated with autoimmunity, in the predisposition and clinical phenotypes of giant cell arteritis (GCA). Methods: Our study population was composed of 911 patients diagnosed with biopsy-proven GCA and 8136 unaffected controls from a Spanish discovery cohort and three additional independent replication cohorts from Germany, Norway and the UK. Two functional PTPN22 polymorphisms (rs2476601/R620W and rs33996649/R263Q) and two variants of the CSK gene (rs1378942 and rs34933034) were genotyped using predesigned TaqMan assays. Results: The analysis of the discovery cohort provided evidence of association of PTPN22 rs2476601/R620W with GCA (PFDR=1.06E-04, OR=1.62, CI 95% 1.29 to 2.04). The association did not appear to follow a specific GCA subphenotype. No statistically significant differences between allele frequencies for the other PTPN22 and CSK genetic variants were evident either in the case/control or in stratified case analysis. To confirm the detected PTPN22 association, three replication cohorts were genotyped, and a consistent association between the PTPN22 rs2476601/R620W variant and GCA was evident in the overall meta-analysis (PMH=2.00E-06, OR=1.51, CI 95% 1.28 to 1.79). Conclusions: Our results suggest that the PTPN22 polymorphism rs2476601/R620W plays an important role in the genetic risk to GCA

Evidence of association of the NLRP1 gene with giant cell arteritis

Recent studies have focused attention on the involvement of NLRP1 to confer susceptibility for extended autoimmune/inflammatory disorders, being considered a common risk factor in autoimmunity. NLRP1 provides a scaffold for the assembly of the inflammasome that activates caspases 1 and 5, required for processing and activation of the proinflammatory cytokines interleukin 1β (IL-1β), IL-18 and IL-33 and promoting inflammation