Analisi Morfometrica dei Cromosomi del Coniglio (Oryctolagus Cuniculus L.)

RIASSUNTOSono stati studiati i cromosomi di coniglio (Oryctolagus cuniculus L.).Il numero diploide dei cromosomi in cellule somatiche e risultato di 2 n= 44. L'analisi morfologica e metrica di essi ha permesso la distinzione in gruppi di cromosomi affini. Una tale classificazione si pensa possa essere utile in ricerche di cariologia comparata nell'ambito dei Leporidae

A New Configuration of Vertical Axis Wind Turbine: Towards the Development of a highly distributed and efficient Wind Power Generation

Preliminary results obtained for a new configuration lift based vertical-axis wind turbine are shown. The turbine rotor is a cross flow fan type made with high curvature aerodynamic profiles. A reduced scale model of the turbine rotor has been designed and preliminary tested at the Department of Aerospace Engineering of the University of Pisa (rotor diameter 250 mm, rotor height 210 mm). The reduced scale model shows an efficiency of about eighteen per cent. The rotor is of a self-starting type. Two-dimensional CFD analyses have been performed applying both the Moving Reference Frame and the Moving Mesh conditions to the grid which surrounds the rotor blades (Fluent® Rel. 6.3 and STAR-CCM+® Rel. 6.04 have been used). Noticeable scale effects have been found numerically, so, the efficiency of a full scale lift based vertical axis multi-blades optimized wind turbine is expected to be comparable with lift based horizontal-axis wind turbines

Gastaut type-idiopathic childhood occipital epilepsy and childhood absence epilepsy: a clinically significant association?

We report an unusual association between idiopathic occipital epilepsy and childhood absence epilepsy in 2 pediatric patients. At first clinical and electroencephalographic evaluation, the patients presented the peculiar signs of idiopathic occipital epilepsy Gastaut type: focal sensory visual seizures, migrainelike symptoms (only in one patient) and unilateral spike–wave discharges over occipital regions. Both children were treated with valproic acid and their seizures were rapidly controlled. After a seizure-free period, the patients presented typical absence with ictal electroencephalographies showing 3 cycles/s generalized and symmetrical spike–wave complexes. We discuss the possible association between these two epileptic syndromes and its common pathophysiological mechanisms

Theoretical status of Bs-mixing and lifetimes of heavy hadrons

We review the theoretical status of the lifetime ratios τB+/τBd, τBs/τBd, τΛb/τBd and τBc and of the mixing quantities ΔMs, ΔΓs and ϕs. ΔMs and ΔΓs suffer from large uncertainties due to the badly known decay constants, while the ratio ΔΓs/ΔMs can be determined with almost no non-perturbative uncertainties, therefore it can be used perfectly to find possible new physics contributions in the mixing parameters. We suggest a very clear method of visualizing the bounds on new physics and demonstrate this by combining the latest experimental numbers on the mixing quantities quantities with theory – one already gets some hints for new physics contributions, but more precise experimental numbers are needed to draw some definite conclusions. We conclude with a ranking list of all the discussed quantities according to their current theoretical uncertainties and point out possible improvements

Managment of diabetic ketoacidosis in children and adolescents in sub-Saharan Africa: A review

Background: Diabetic ketoacidosis (DKA) is a complex metabolic state of hyperglycaemia, ketosis, and acidosis. Diabetes in sub-Saharan Africa is, in many patients a serious disease with a poor prognosis. Most deaths, however, are due to preventable causes.Objective: To improve knowledge on the management of DKA in sub-Saharan Africa.Data sources: Literature review from different published sources. Data synthesis: Health systems in sub-Saharan Africa are currently organised for the treatment of episodes of illness and not long-term conditions like diabetes. Therefore the high rates of DKA is essentially due to lack of training of health professionals, lack of facilities in most hospitals, lack of public awareness as well as lack of health education to individual patients/families. In addition erratic insulin supply coupling with infections, low parental education, poor insulin storage and lack of facilities for self monitoring of blood glucose.Conclusion: A complex unfavourable social and economic environment is the basis of the high prevalence of DKA in sub-Saharan Africa. Several episodes of DKA can be prevented by effective public awareness programmes and education to healthcare providers

Cognitive and linguistic abnormalities in benign childhood epilepsy with centrotemporal spikes

Aim: To assess the cognitive function and language ability in children with benign partial epilepsy with centrotemporal spikes. Methods: Twenty-five patients with benign partial epilepsy with centrotemporal spikes were included. They were divided into two subgroups. Group I: 10 patients with rolandic focus who were not treated. Group II: 15 patients with rolandic focus receiving treatment. A third Group of 12 healthy subjects have been studied. All children underwent standardized neuropsychological testing: electroencephalogram recording, Wechsler Intelligence Scale for Children-revised, Peabody Picture Vocabulary Test-III (PPVT-III) and Boston Naming Test (BNT), both during active disease (T1) and 2 years after recovery from epilepsy (T2). Results: At T1 evaluation, no significant differences in group I and II patients about general intelligence, when compared with controls, were found. Group I and II patients were impaired with respect to controls in the receptive and expressive vocabulary evaluated with PCVT-III and BNT, respectively. At T2 evaluation, group I and II patients showed a normalization of the language abnormalities. Conclusion: Deficits of speech-related abilities can be detected in children with this type of epilepsy: these dysfunctions seem to be independent of the effects of antiepileptic treatment and are reversible after remission of epilepsy

Experiencia didáctica con dinosaurios

Esta experiencia se realizo en la ciudad La Plata en el año 2002 en el Parque Ecológico de esa ciudad luego en el 2003, nos invitaron a participar en la institución, La Republica de los Niños de dicha ciudad, hasta mediados de 2008. La experiencia estuvo dirigida a niños entre 4 y 10 años, ofreciendo una visión sobre nuevas teorías, descripción de los diferentes taxones, procesos evolutivos de los diferentes grupos, creímos conveniente introducir otros temas relacionados, como Deriva continental, extinción de las distintas familias de dinosaurios, etc. El Taller se llevó a cabo en tres etapas: Una exposición oral, tratando principales temas como el origen de los dinosaurios, los diferentes cambios del planeta Tierra en esos períodos (tanto geográfica como climáticamente), hasta llegar a la extinción del grupo. Una segunda etapa, tratamos mediante un experimento, demostrar procesos de fosilización de estos grupos, la ultima parte de este taller, se enfoco en explicar el trabajo del paleontólogo en el campo y luego en laboratorio, esta sección era una de las mas importantes, padres y niños trabajaban juntos. El taller contó con la presencia de más de cinco mil niños y varias participaciones a diferentes establecimientos escolares y centros culturales de La Plata, Ensenada, Berisso y conurbano bonaerense.Trabajos del área Ciencias NaturalesDepartamento de Ciencias Exactas y Naturale

One-hour post-load plasma glucose levels associated with decreased insulin sensitivity and secretion and early makers of cardiometabolic risk.

PURPOSE: Obese adults with normal glucose tolerance (NGT) but with 1-hour post-load plasma glucose (1hPG) ≥ 155 mg/dl are at higher risk of developing type 2 diabetes (T2D) and cardiometabolic complications. Little information is available for the pediatric population, where recently, a lower cutoff, 132.5 mg/dl, has been suggested as being more sensitive to identify subjects at risk of T2D. Our aim was to assess whether obese Caucasian youth with 1hPG ≥ 132.5 mg/dl have worse insulin sensitivity and secretion and a worse cardiometabolic profile compared to obese youth with 1hPG < 132.5 mg/dl. METHODS: Medical records of 244 (43% male; age: 11.1 ± 2.7years) overweight/obese children and adolescents, who had undergone an oral glucose tolerance test (OGTT), were retrieved. Anthropometric and biochemical data were collected from the hard copy archive. Indexes of insulin resistance (HOMA-IR), insulin sensitivity (WBISI), and insulin secretion (Insulinogenic Index, Disposition Index) were calculated. RESULTS: Of the 244 records analyzed, 215 fulfilled criteria for NGT and had complete biochemical data. Among NGT patients, 42 (19.5%) showed 1hPG ≥ 132.5 mg/dL (high-NGT), while the remaining had 1hPG < 132.5 mg/dL (low-NGT). The high-NGT group showed a higher male prevalence (59.5 vs 37%), lower Disposition Index (0.54 [0.39-0.71] vs 0.79 [0.47-1.43]), and WBISI (0.24 [0.18-0.35] vs 0.33 [0.23-0.50]) than the low-NGT group. High-NGT subjects also showed a trend towards lower HDL-cholesterol and higher triglycerides/HDL-cholesterol ratio (2.13 [1.49-3.41] vs 1.66 [1.24-2.49]). CONCLUSIONS: In overweight/obese NGT Caucasian youth a 1hPG ≥ 132.5 mg/dL was able to identify those with impaired insulin sensitivity and secretion and a trend towards a worse cardio-metabolic profile, a group likely at risk for future T2D