Statistical approach to optimization of the transesterification reaction from sorrel (hibiscus sabdariffa) oil

In an effort to optimize the reaction conditions of biodiesel production from Sorrel seed oil, Response Surface Methodology (RSM) was applied and the effects of reaction temperature, catalyst amount, reaction time and methanol/oil molar ratio, and their reciprocal interactions were ascertained. A total of 30 experimental runs were designed by Central Composite Rotatable Design (CCRD) and carried out. A quadratic polynomial was obtained for predicting the Transesterification process and the ANOVA test showed the model to be significant (p<0.05). The validity of the predicted model was confirmed by carrying out three independent replicates experiments. The actual maximum biodiesel yield obtained was 99.23% (w/w) at methanol/oil molar ratio 6.21, catalyst amount 1.03 (% wt.), reaction temperature 51 oC, and reaction time 63 min. The fuel properties of Hibiscus sabdariffa methylester (HSME) produced were found to be within the ASTM D6751 and DIN EN 14214 biodiesel standards. The fatty acid profile of the HSME revealed that the dominant fatty acids were oleic (58.34%), arachidic (1.55%), palmitic (18.28%) and linoleic (21.19%). Emission assessment revealed 70% reduction of CO at B80, 80% reduction of NO concentration at B40

Acid-Catalyzed Esterification of Waste Cooking Oil with High FFA for Biodiesel Production

In this work, Biodiesel was produced from waste cooking oil (WCO) obtained from Mr. Biggs.  Since WCO usually comes with a high content of FFA and thus requires an additional acid pre-treatment process to convert the FFA to ester. Two steps (esterification and transesterification) approach was employed to convert the WCO to biodiesel. In the first step, six experimental run was carried out until the % FFA was constant. Meanwhile, the second step required five experimental runs, and the average WCO biodiesel yield (95.06 % w/w) was computed at the following variable conditions, 0.55% KOH, 5:1 Methanol/oil molar ratio, 60 oC reaction temperature and 30 min reaction time. Meanwhile, the produced WCO biodiesel possess some fuel properties which satisfied both ASTME D6751 and EN 1424 standards. The fatty acid profiles of both the WCO and WCO biodiesel revealed that both profiles contained unsaturated fatty acids. Hence, it can be concluded that WCO is a potential raw material for biodiesel production which are biodegradable, economical, environmental friendly and always available. Keywords: Waste cooking oil (WCO), esterification, transesterification, biodiesel, fatty acids profile, physicochemical analysis

HCME: An Environment-Friendly I.C. Engine Fuel

The study revealed that Hura crepitans oil is a good candidate for Hura crepitans methyl ester (HCME) production. Two steps (esterification and transesterification) production stages influenced the high yield of HCME. Three possible experimental runs were performed in each step, the best of the three conditions were 1.45 (% v/v) for H2SO4 conc., 5:1 for methanol/oil molar ratio, 40 min for reaction time which gave 1.06 % for FFA in the first step, in the second step, 92.70 %(w/w) of HCME was obtained at 0.55% KOH, 5:1 methanol/oil molar ratio, 60 oC temperature and 30 min reaction time. The produced HCME had fuel properties which satisfied both ASTME D6751 and EN 1424 standards. The fatty acid profile of the HCME revealed the dominant fatty acids were linoleic (64.50%), oleic (17.54%) and palmitic (12.70%). Exhaust emissions from an internal combustion (I.C.) engine revealed that there is 60% decreased in CO, 58% decreased in NOx, 60% decreased in HC, 39% decrease in smoke opacity and 42% decreased in BSFC at B20, respectively. Flue gas temperature increased by 12% at B20, 45% increased in BTE at B50 when compared to pure diesel (AGO). Hence, it can be concluded that B20 (20% HCME + 80% AGO) will provides the best emission reduction at the lowest cost

Functional Properties of Corn Starch Extracted from Four Varieties of Maize (Zea Mays)

This study entails extraction and evaluation of starch from four varieties of Zea mays. From the results of the study, yellow maize and popcorn had higher water holding capacity than regular white maize and quality protein maize

Assessing the challenges impeding effective primary health care delivery in Southwest Nigeria

This study seeks to investigate the challenges impeding healthcare delivery in selected Primary Health Care facilities in South West Nigeria. A quantitative approach was adopted with purposive sampling of 241 health workers across PHC facilities in South West Nigeria. Data was analysed using the Statistical Package for Social Science (SPSS version 22). The study revealed seven main challenges which included shortage of manpower, inadequate medical equipment, lack of employee motivation, lack of basic infrastructure, unavailability of drugs, poor funding and cultural belief. Consequent upon these findings, government interventions such as employment of more skilled personnel, improved working conditions, employee motivation, provision of basic facilities/equipment and better financing, is required to enhance the quality of service and sustainability of PHC in Nigeri

Treatment-shortening regimens for tuberculosis: updates and future priorities

In the past 2 years, remarkable advances have been made in shortening tuberculosis (TB) treatment. In particular, four clinical trials (Study 31/A5349, Nix-TB, ZeNix and TB-PRACTECAL) have provided evidence of the efficacy of regimens based on new and repurposed drugs: the 4-month regimen for drug-susceptible TB, and the 6-month bedaquiline–pretomanid–linezolid regimen with or without moxifloxacin for multidrug-resistant/rifampicin-resistant TB. Even if the evidence at the basis of these new regimens is compelling, several questions remain open, particularly concerning linezolid dose finding, the upsurging threat of bedaquiline-resistant Mycobacterium tuberculosis and the feasibility of applying these results to the paediatric population. Several ongoing trials may fill the remaining gaps and produce further reliable evidence to address the outstanding questions in TB treatment shortening

Evaluation of the Community Cataract Surgical Services of a University Teaching Hospital Using Cataract Surgical Coverage in Nigeria

Background: Cataract is the leading cause of blindness in the world. An efficient and effective cataract surgical service is necessary to reduce the backlog of cataract blindness in the community. This study aims to determine the cataract surgical coverage among individuals aged 50 years and above residing in Esie and Arandun communities. This will serve as a measure of the impact of the cataract intervention programme provided by the University of Ilorin Teaching Hospital, Nigeria.Methods: The study was a population-based, cross sectional survey conducted from November to December, 2013. Cataract surgical services are provided by the University of Ilorin Teaching Hospital, Nigeria, at Esie and Arandun communities as out-reach centres. Seven hundred and fifty-five individuals aged 50 years and above residing in these communities had basic ocular examination done.Result: Out of the 765 subjects registered, 755(98.7%) were examined. Out of these, 38.4% were males and 61.6% were females. The prevalence of bilateral cataract blindness was 1.6%. The Cataract Surgical Coverage (eyes) at visual acuity &lt; 3/60 for males and females were 52.3% and 51.2% respectively (X2=19.30, p=0.001), while the Cataract Surgical Coverage (person) at visual acuity less &lt; 3/60 for males and females were 80.6% and 68.4% respectively (X2=2.10, p=0.147).Conclusion: The Cataract Surgical Coverage was high with a correspondingly low prevalence of cataract blindness in these communities. The availability of cataract surgical services via out-reach programmes bridges the gap between eye care-givers and the community.Keywords: Cataract Surgical Coverage, Cataract Surgical Services, Community, Evaluatio

Prevalence of stroke in three semi-urban communities in middle-belt region of Nigeria: A door to door survey

Introduction: the burden of stroke has been projected to increase for developing countries, but data are limited, especially in sub-Saharan Africa.This necessitated this study to determine the stroke prevalence in a semi urban community in middle-belt region of Nigeria. Methods: a twophasedoor-to-door study was performed in three semi-urban communities of  Kwara state; in the first phase 12,992 residents were screened andprobable stroke cases were identified by trained health care workers. In the second phase individuals adjudged to be positive for stroke were screened with a stroke-specific questionnaire and made to undergo a complete  neurological examination by a neurologist. Stroke diagnosis was based on clinical evaluation using WHO criteria. Results: out of the numbers that were screened, 18 probable stroke cases were identified in the first stage, and of these, 17 fulfilled WHO criteria for stroke, giving a crude prevalence rate of 1.31/1000 population. The prevalence of stroke was higher among the males than the females (1.54/1000 vs. 1.08/1000) with a ratio 1.4: 1. Sixteen subjects (94.1%) had one or more risk factors for stroke.  Uncontrolled systemic hypertension (82.4%) was the commonest risk  factors for stroke followed by transient ischaemic attack (TIA) (41.2%). Conclusion: stroke is a condition that is prevalent in our environment; especially in older adults and men. Uncontrolled systemic hypertension and previous transient ischaemic attacks were the commonest risk factors for stroke in our community

Awareness of Diabetic Retinopathy among patients with Diabetes Mellitus in Ilorin, Nigeria

Background: Diabetic retinopathy is a major cause of blindness worldwide. The associated loss of productivity and quality of life of the patients with diabetic retinopathy will lead to additional socioeconomic burden. This study aims to determine the level of awareness of diabetic retinopathy among diabetic patients. Materials and Methods: This hospital-based cross sectional study, was carried out at the Diabetic and Ophthalmology clinics of University of Ilorin Teaching Hospital, Nigeria from November 2011 to July 2012. A total of 365 patients had validated, semi-structured, and interviewer-administered questionnaires to obtain information on socio-demographic characteristics, clinical information and awareness of diabetic retinopathy. Results: A total of 365 patients were enrolled, with age between 19 and 90 years, and a mean of 45.8 ±16.3 years. The male to female ratio was 1: 2.2. Ninety-nine respondents (27.1%) had no education. The majority (30.4%) had only primary education; 21.1% had tertiary; 14.5% had secondary while 6.8% had Quranic education. The mean duration of diabetes mellitus was 14.1 ±13.09 years. Of the 365 patients with diabetes mellitus, 279(76.4%) had heard that diabetes mellitus affects the eyes, while 86(23.6%) had not. Of those who had heard, 221(79.2%) heard it from health personnel, 45(16.1%) from radio/television, 25(9.0%) from internet, 23(8.2%) from books/newspapers, while 16(5.7%) heard from other sources.Conclusion: There was a high level of awareness of diabetic retinopathy amongst the patients. However, the high level of awareness of the blinding complication of diabetes mellitus did not translate to a correspondingly high level of ocular examination for diabetic retinopathy.