329 research outputs found

    Correlation between live weight and body measurements in certain dog breeds

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    The purpose of this study was to determine the correlation between live weight and body measurements in Zagar, Zerdava, and Catalburun dogs. Animal materials were obtained from various regions of Turkey. A total of 304 dogs from three breeds were used: Zagar (45 females, 59 males), Zerdava (50 females, 50 males), and Catalburun (62 females, 38 males). Live weights and certain body measurements were determined. A linear regression model was created using the parameters obtained in this study. The bodyweights calculated with the body measurements were found to be at a high or acceptable level in the Zagar, Zerdava, and Catalburun genotypes (R-2 = 0.902, 0.467, and 0.697, respectively).Scientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK)The authors would like to thank Scientific and Technological Research Council of Turkey (TUBITAK) and the owners of the Zagar, Zerdava and Catalburun dogs for their support to the project

    Optical transitions of Tm3+ ions for amplifiers: How the local structure works in (1 - Ex)TeO2 + (x)M (where M = LiCl, CdCl2, WO3) glass

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    Optical transitions of Tm3+ ions for amplifiers was presented. Stimulated emission cross-section at the peak wavelength of the emission bands was determined. It was concluded that Tm3+ doped binary tellurite glasses are promising materials for the infrared amplifiers

    Energy optimisation models for self-sufficiency of a typical turkish residential electricity customer of the future

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    This paper utilises a two-stage demand response-enabled energy management algorithm for a typical Turkish self-sufficient living space. The proposed energy management model provides an additional gain in line with the goal of self-sufficiency by scheduling flexible loads and energy storage systems at home according to a static time of use tariff. The impact of load scheduling and battery optimisation were evaluated in the scope of self-sufficiency, economic gain and return on investment performances. According to the results, the proposed two-stage structure provided a net saving increase of 9.5% in the one-battery scenario, and it rises to 14% in the design with three batteries. On the other hand, when we inspect the energy management scenarios with the return on investment (ROI) calculations, we see that the single battery system has a higher ROI than the two or three battery systems due to the increased battery cost. Moreover, the ROI value, 13.9% without optimisation, increased to 15.3% in the proposed Home Energy Management System (HEMS) model. As can be seen from this calculation, intelligent management of batteries and flexible loads provided a 10% increase in ROI value.</jats:p

    New features for child metrics: Further growth references and blood pressure calculations

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    Many new features have recently been incorporated to CEDD Cozum/Child Metrics, an online and freely accessible scientific toolset. Various auxological assessments can now be made with data of children with genetic diseases (Prader Willi syndrome, Noonan syndrome, Turner syndrome, Down syndrome, and Achondroplasia) and preterm and term newborns. More detailed reports for height, weight, and body mass index data of a given child are now available. Last but not least, office and 24-hour ambulatory blood pressure values can be analyzed according to normative data

    Turner syndrome and associated problems in turkish children: A multicenter study

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    Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls. This study aimed to systematically investigate the key clinical features of TS in relationship to karyotype in a large pediatric Turkish patient population. Methods: Our retrospective study included 842 karyotype-proven TS patients aged 0-18 years who were evaluated in 35 different centers in Turkey in the years 2013-2014. Results: The most common karyotype was 45,X (50.7%), followed by 45,X/46,XX (10.8%), 46,X,i(Xq) (10.1%) and 45,X/46,X,i(Xq) (9.5%). Mean age at diagnosis was 10.2±4.4 years. The most common presenting complaints were short stature and delayed puberty. Among patients diagnosed before age one year, the ratio of karyotype 45,X was significantly higher than that of other karyotype groups. Cardiac defects (bicuspid aortic valve, coarctation of the aorta and aortic stenosi) were the most common congenital anomalies, occurring in 25% of the TS cases. This was followed by urinary system anomalies (horseshoe kidney, double collector duct system and renal rotation) detected in 16.3%. Hashimoto’s thyroiditis was found in 11.1% of patients, gastrointestinal abnormalities in 8.9%, ear nose and throat problems in 22.6%, dermatologic problems in 21.8% and osteoporosis in 15.3%. Learning difficulties and/or psychosocial problems were encountered in 39.1%. Insulin resistance and impaired fasting glucose were detected in 3.4% and 2.2%, respectively. Dyslipidemia prevalence was 11.4%. Conclusion: This comprehensive study systematically evaluated the largest group of karyotype-proven TS girls to date. The karyotype distribution, congenital anomaly and comorbidity profile closely parallel that from other countries and support the need for close medical surveillance of these complex patients throughout their lifespan. © Journal of Clinical Research in Pediatric Endocrinology

    Mapping the Two-Component Atomic Fermi Gas to the Nuclear Shell-Model

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    The physics of a two-component cold fermi gas is now frequently addressed in laboratories. Usually this is done for large samples of tens to hundreds of thousands of particles. However, it is now possible to produce few-body systems (1-100 particles) in very tight traps where the shell structure of the external potential becomes important. A system of two-species fermionic cold atoms with an attractive zero-range interaction is analogous to a simple model of nucleus in which neutrons and protons interact only through a residual pairing interaction. In this article, we discuss how the problem of a two-component atomic fermi gas in a tight external trap can be mapped to the nuclear shell model so that readily available many-body techniques in nuclear physics, such as the Shell Model Monte Carlo (SMMC) method, can be directly applied to the study of these systems. We demonstrate an application of the SMMC method by estimating the pairing correlations in a small two-component Fermi system with moderate-to-strong short-range two-body interactions in a three-dimensional harmonic external trapping potential.Comment: 13 pages, 3 figures. Final versio

    Molecular Basis for Drug Resistance in HIV-1 Protease

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    HIV-1 protease is one of the major antiviral targets in the treatment of patients infected with HIV-1. The nine FDA approved HIV-1 protease inhibitors were developed with extensive use of structure-based drug design, thus the atomic details of how the inhibitors bind are well characterized. From this structural understanding the molecular basis for drug resistance in HIV-1 protease can be elucidated. Selected mutations in response to therapy and diversity between clades in HIV-1 protease have altered the shape of the active site, potentially altered the dynamics and even altered the sequence of the cleavage sites in the Gag polyprotein. All of these interdependent changes act in synergy to confer drug resistance while simultaneously maintaining the fitness of the virus. New strategies, such as incorporation of the substrate envelope constraint to design robust inhibitors that incorporate details of HIV-1 protease’s function and decrease the probability of drug resistance, are necessary to continue to effectively target this key protein in HIV-1 life cycle
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