Estructura cristalina de ADN y su utilización para la identificación de fármacos

Estructura cristalina de ADN y su utilización para la identificación de fármacos. La estructura cristalina que comprende un entrecruzamiento de tres cadenas de ADN está caracterizada porque: pertenece al grupo espacial P4(1)32 y tiene unas dimensiones de celda a=b=c=70,98 ± 0,7°A; todos los nucleótidos que constituyen dichas cadenas de ADN se encuentran emparejados; y dicho entrecruzamiento de tres cadenas de ADN alberga, en una cavidad hidrofóbica, una molécula. La estructura cristalina de la invención es una diana adecuada para el diseño de fármacos anti-ADN con una elevada especificidad.Peer reviewedConsejo Superior de Investigaciones Científicas (España)B1 Patente sin examen previ

Development of Photocatalytically Active Anodized Layers by a Modified Phosphoric Acid Anodizing Process for Air Purification

One of the key urban air quality issues is pollution by nitrogen oxides (NOx). To reduce NOx, facade cladding could be provided with photocatalytic properties by incorporating titanium dioxide nanoparticles. For this purpose, a modified phosphoric acid anodizing process (MPAA) was developed for the facade alloy EN AW-5005, in which highly ordered anodized structures with a low degree of arborization and tortuosity were produced. Pore widths between 70 nm and 150 nm and layer thicknesses of about 2–3 m were obtained. The subsequent impregnation was carried out by dip coating from water-based systems. Depending on the dip-coating parameters and the suspension used, the pores can be filled up to 60% with the TiO2 nanoparticles. Photocatalytic tests according to ISO 22197-1 certify a high photocatalytic activity was obtained with rPCE values > 8 and with rPCE > 2, achieving “photocatalytically active for air purification”. Tests on the corrosion resistance of the anodized coatings with a commercially available aluminum and facade cleaner confirm a protective effect of the anodized coatings when compared with nonanodized aluminum material, as well as with compacted anodized layers

Chromate-free smart release corrosion inhibitive pigments containing cations

A smart release chrome-free inhibiting system is utilised in an organic coating system to inhibit cathodic disbondment of hot dip galvanised steel. The non-toxic smart release cation system is relatively cheap, easy to process and highly effective. An in-situ scanning Kelvin probe is used to assess the protection offered by the cation containing pigments in a poly-vinyl-butyral model coating. The inhibition of cathodic delamination under the SKP testing conditions exceeds that of hexavalent chromate by the inhibitor system containing magnesium(II) ions

Special Issue: Advanced Coatings for Corrosion Protection

Corrosion is an important issue in many industrial fields. Among others, coatings are by far the most important technology for corrosion protection of metallic surfaces. The special issue “Advanced Coatings for Corrosion Protection” has been launched as a means to present recent developments on any type of advanced coatings for corrosion protection. Fifteen contributions have been collected on metallic, inorganic, polymeric and nanoparticle enhanced coatings providing corrosion protection as well as partly other functionalities

Neue Ansätze zum Korrosionsschutz für Metalle durch nanopartikuläre Schichtsysteme und nanoskalige Polymerfilme

This thesis describes the strongly interdisciplinary work carried out in the corrosion group at the Karl-Winnacker-Institute of DECHEMA e.V. on the development of new ways of corrosion protection for metals by a combination of chemical nanotechnology and materials sciences. On the one hand by following innovative nanotechnological concepts oxidic nanoparticles were used to produce or modify inorganic coating systems. On the other hand nano-scaled polymer films have been investigated as self-assembling adhesion promoter films and as biogenic protective coatings against microbially influenced corrosion processes