2,060 research outputs found
Exact relations between multifractal exponents at the Anderson transition
Two exact relations between mutlifractal exponents are shown to hold at the
critical point of the Anderson localization transition. The first relation
implies a symmetry of the multifractal spectrum linking the multifractal
exponents with indices . The second relation
connects the wave function multifractality to that of Wigner delay times in a
system with a lead attached.Comment: 4 pages, 3 figure
Fluctuations and scaling of inverse participation ratios in random binary resonant composites
We study the statistics of local field distribution solved by the
Green's-function formalism (GFF) [Y. Gu et al., Phys. Rev. B {\bf 59} 12847
(1999)] in the disordered binary resonant composites. For a percolating
network, the inverse participation ratios (IPR) with are illustrated, as
well as the typical local field distributions of localized and extended states.
Numerical calculations indicate that for a definite fraction the
distribution function of IPR has a scale invariant form. It is also shown
the scaling behavior of the ensemble averaged described by the
fractal dimension . To relate the eigenvectors correlations to resonance
level statistics, the axial symmetry between and the spectral
compressibility is obtained.Comment: 7 pages, 6 figures, accepted by Physical Review
Speaker Localization with Moving Microphone Arrays
Speaker localization algorithms often assume static location for all sensors. This assumption simplifies the models used, since all acoustic transfer functions are linear time invariant. In many applications this assumption is not valid. In this paper we address the localization challenge with moving microphone arrays. We propose two algorithms to find the speaker position. The first approach is a batch algorithm based on the maximum likelihood criterion, optimized via expectationmaximization iterations. The second approach is a particle filter for sequential Bayesian estimation. The performance of both approaches is evaluated and compared for simulated reverberant audio data from a microphone array with two sensors
Light propagation through closed-loop atomic media beyond the multiphoton resonance condition
The light propagation of a probe field pulse in a four-level double-lambda
type system driven by laser fields that form a closed interaction loop is
studied. Due to the finite frequency width of the probe pulse, a
time-independent analysis relying on the multiphoton resonance assumption is
insufficient. Thus we apply a Floquet decomposition of the equations of motion
to solve the time-dependent problem beyond the multiphoton resonance condition.
We find that the various Floquet components can be interpreted in terms of
different scattering processes, and that the medium response oscillating in
phase with the probe field in general is not phase-dependent. The phase
dependence arises from a scattering of the coupling fields into the probe field
mode at a frequency which in general differs from the probe field frequency. We
thus conclude that in particular for short pulses with a large frequency width,
inducing a closed loop interaction contour may not be advantageous, since
otherwise the phase-dependent medium response may lead to a distortion of the
pulse shape. Finally, using our time-dependent analysis, we demonstrate that
both the closed-loop and the non-closed loop configuration allow for sub- and
superluminal light propagation with small absorption or even gain. Further, we
identify one of the coupling field Rabi frequencies as a control parameter that
allows to conveniently switch between sub- and superluminal light propagation.Comment: 10 pages, 8 figure
Evidence for a meteoritic origin of the September 15, 2007, Carancas crater
On September 15th, 2007, around 11:45 local time in Peru, near the Bolivian border, the
atmospheric entry of a meteoroid produced bright lights in the sky and intense detonations. Soon after,
a crater was discovered south of Lake Titicaca. These events have been detected by the Bolivian
seismic network and two infrasound arrays operating for the Comprehensive Nuclear-Test-Ban Treaty
Organization, situated at about 80 and 1620 km from the crater. The localization and origin time
computed with the seismic records are consistent with the reported impact. The entry elevation and
azimuthal angles of the trajectory are estimated from the observed signal time sequences and backazimuths.
From the crater diameter and the airwave amplitudes, the kinetic energy, mass and
explosive energy are calculated. Using the estimated velocity of the meteoroid and similarity criteria
between orbital elements, an association with possible parent asteroids is attempted. The favorable
setting of this event provides a unique opportunity to evaluate physical and kinematic parameters of
the object that generated the first actual terrestrial meteorite impact seismically recorded
Impact of electrode density of states on transport through pyridine-linked single molecule junctions
We study the impact of electrode band structure on transport through
single-molecule junctions by measuring the conductance of pyridine-based
molecules using Ag and Au electrodes. Our experiments are carried out using the
scanning tunneling microscope based break-junction technique and are supported
by density functional theory based calculations. We find from both experiments
and calculations that the coupling of the dominant transport orbital to the
metal is stronger for Au-based junctions when compared with Ag-based junctions.
We attribute this difference to relativistic effects, which results in an
enhanced density of d-states at the Fermi energy for Au compared with Ag. We
further show that the alignment of the conducting orbital relative to the Fermi
level does not follow the work function difference between two metals and is
different for conjugated and saturated systems. We thus demonstrate that the
details of the molecular level alignment and electronic coupling in
metal-organic interfaces do not follow simple rules, but are rather the
consequence of subtle local interactions
In situ tropical peatland ire emission factors and their variability, as determined by field measurements in peninsula Malaysia
Fires in tropical peatlands account for >25% of estimated total greenhouse gas emissions from deforestation and degradation. Despite significant global and regional impacts, our understanding of specific gaseous fire emission factors (EFs) from tropical peat burning is limited to a handful of studies. Furthermore, there is substantial variability in EFs between sampled fires and/or studies. For example, methane EFs vary by 91% between studies. Here we present new fire EFs for the tropical peatland ecosystem; the first EFs measured for Malaysian peatlands, and only the second comprehensive study of EFs in this crucial environment. During August 2015 (under El Niño conditions) and July 2016, we embarked on field campaigns to measure gaseous emissions at multiple peatland fires burning on deforested land in Southeast Pahang (2015) and oil palm plantations in North Selangor (2016), Peninsula Malaysia. Gaseous emissions were measured using open-path Fourier transform infrared spectroscopy. The IR spectra were used to retrieve mole fractions of 12 different gases present within the smoke (including carbon dioxide and methane), and these measurements used to calculate EFs. Peat samples were taken at each burn site for physicochemical analysis and to explore possible relationships between specific physicochemical properties and fire EFs. Here we present the first evidence to indicate that substrate bulk density affects methane fire EFs reported here. This novel explanation of interplume, within-biome variability, should be considered by those undertaking greenhouse gas accounting and haze forecasting in this region and is of importance to peatland management, particularly with respect to artificial compaction
Activation of c-Met and Upregulation of CD44 Expression are Associated with the Metastatic Phenotype in the Colorectal Cancer Liver Metastasis Model
Background
Liver metastasis is the most common cause of death in patients with colorectal cancer. Despite extensive research into the biology of cancer progression, the molecular mechanisms that drive colorectal cancer metastasis are not well characterized.
Methods
HT29 LM1, HT29 LM2, HT29 LM3 cell lines were derived from the human colorectal cancer cell line HT29 following multiple rounds of in vivo selection in immunodeficient mice.
Results
CD44 expression, a transmembrane glycoprotein involved in cell-cell and cell-matrix adhesions, and cancer cells adhesion to endothelial cells was increased in all in vivo selected cell lines, with maximum CD44 expression and cancer cells adhesion to endothelial cells in the highly metastatic HT29 LM3 cell line. Activation of c-Met upon hepatocyte growth factor (HGF) stimulation in the in vivo selected cell lines is CD44 independent. In vitro separation of CD44 high and low expression cells from HT29 LM3 cell line with FACS sorting confirmed that c-Met activation is CD44 independent upon hepatocyte growth factor stimulation. Furthermore, in vivo evaluation of CD44 low and high expressing HT29 LM3 cells demonstrated no difference in liver metastasis penetrance.
Conclusions
Taken together, our findings indicate that the aggressive metastatic phenotype of in vivo selected cell lines is associated with overexpression of CD44 and activation of c-MET. We demonstrate that c-Met activation is CD44 independent upon hepatocyte growth factor stimulation and confirm that CD44 expression in HT29 LM3 cell line is not responsible for the increase in metastatic penetrance in HT29 LM3 cell line
Relativistic and Radiative Corrections to the Mollow Spectrum
The incoherent, inelastic part of the resonance fluorescence spectrum of a
laser-driven atom is known as the Mollow spectrum [B. R. Mollow, Phys. Rev.
188, 1969 (1969)]. Starting from this level of description, we discuss
theoretical foundations of high-precision spectroscopy using the resonance
fluorescence light of strongly laser-driven atoms. Specifically, we evaluate
the leading relativistic and radiative corrections to the Mollow spectrum, up
to the relative orders of (Z alpha)^2 and alpha(Z alpha)^2, respectively, and
Bloch-Siegert shifts as well as stimulated radiative corrections involving
off-resonant virtual states. Complete results are provided for the hydrogen
1S-2P_{1/2} and 1S-2P_{3/2} transitions; these include all relevant correction
terms up to the specified order of approximation and could directly be compared
to experimental data. As an application, the outcome of such experiments would
allow for a sensitive test of the validity of the dressed-state basis as the
natural description of the combined atom-laser system.Comment: 20 pages, 1 figure; RevTe
TSC2/mTORC1 Signaling Controls Paneth and Goblet Cell Differentiation in the Intestinal Epithelium
The intestinal mucosa undergoes a continual process of proliferation, differentiation and apoptosis, which is regulated by multiple signaling pathways. Notch signaling is critical for the control of intestinal stem cell maintenance and differentiation. However, the precise mechanisms involved in the regulation of differentiation are not fully understood. Previously, we have shown that tuberous sclerosis 2 (TSC2) positively regulates the expression of the goblet cell differentiation marker, MUC2, in intestinal cells. Using transgenic mice constitutively expressing a dominant negative TSC2 allele, we observed that TSC2 inactivation increased mTORC1 and Notch activities, and altered differentiation throughout the intestinal epithelium, with a marked decrease in the goblet and Paneth cell lineages. Conversely, treatment of mice with either Notch inhibitor dibenzazepine (DBZ) or mTORC1 inhibitor rapamycin significantly attenuated the reduction of goblet and Paneth cells. Accordingly, knockdown of TSC2 activated, whereas knockdown of mTOR or treatment with rapamycin decreased, the activity of Notch signaling in the intestinal cell line LS174T. Importantly, our findings demonstrate that TSC2/mTORC1 signaling contributes to the maintenance of intestinal epithelium homeostasis by regulating Notch activity
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