Qualidade de Vida no Trabalho (QVT) : uma análise na Universidade Federal do Acre – Campus Rio Branco

Monografia (graduação)—Ministério da Educação, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Diretoria de Educação a Distância, Universidade Aberta do Brasil, Programa Nacional de Formação em Administração Pública, Universidade de Brasília, 2015.O presente trabalho debruça-se sobre uma análise da qualidade de vida no trabalho (QVT) na Universidade Federal do Acre – UFAC, campus Rio Branco; tendo para isto a colaboração de servidores docentes e não docentes do quadro efetivo da instituição. Buscou-se compreender se as ações de QVT já pontualmente empreendidas na organização recebem o devido suporte da alta administração da instituição, recorrendo-se do ponto de vista teórico-metodológico às contribuições de diversos estudiosos sobre a temática, com destaque para Walton (1973) e Hackman-Oldham (1975) substanciais à elaboração dos instrumentos avaliativos, bem como, o devido tratamento dos dados. A metodologia utilizada para o desenvolvimento do estudo de caso se fora a aplicação de questionários estruturados. Os resultados apontam que muitas atividades já têm recebido o devido patrocínio do nível estratégico da organização, em especial as relacionadas às condições de trabalho, porém ainda existem certas lacunas que precisam ser mais bem trabalhadas, como o grau de intensidade e repetição das atividades no ambiente de trabalho. _________________________________________________________________________________ ABSTRACTThe present work focuses on a life of quality analysis at work (QVT) at the Federal University of Acre - UFAC, Rio Branco campus; having for this collaboration servers teachers and non-teaching staff of the permanent staff of the institution. He sought to understand whether the QVT actions have occasionally undertaken in the organization receive proper support from senior management of the institution, are resorting to this, the theoretical and methodological point of view, to the contributions of many scholars on the subject, highlighting Walton (1973) and Hackman-Oldham (1975) substantial to the development of evaluation tools, as well as the proper treatment of the data. The methodology used to develop the case study was the application of structured questionnaires. The results show that many activities have already received the sponsorship because the strategic level of the organization, especially those relating to working conditions, but there are still some gaps that need to be better treated, such as the intensity and repetition of the activities in the workplace

The 9-Anthroate chromophore as a fluorescent probe for water

Water quenches the fluorescence of methyl 9-anthroate with a rate constant showing little dependence on solvent viscosity or polarity. In dioxane, at 20ºC the value of the rate constant is 9.6 X 10^6 M^(-1) s^(-1) , and the activation energy found for the process is 14.1 kJ mol^(-1). The quenching process is entropy-controlled and is likely to involve a hydrogen-bonded complex as an intermediate. Since the fluorescence lifetime of methyl 9-anthroate does not depend on the solvent properties other than its hydrogen-bonding ability, the concentration of nearby water can be estimated directly. Values of 3, 54, and 14 M were obtained for the solubilization site of methyl 9-anthroate in micelles of Triton X-100, sodium dodecyl sulfate (SDS), and dodecyltrimethylammonium chloride (DTAC), respectively. From the ring current effect of the anthroate group on the 'H NMR chemical shifts of the surfactant protons, it is concluded that the anthroate fluorescent probe is preferentially located in the surface region of the SDS and DTAC micelles; however, in Triton X-100, it resides in the micelle interior near the phenoxy groups of the surfactant molecule

Cleantechs and Digital Solutions for Sustainability in the Brazilian Energy Sector

This paper aims to map the main digital solutions practiced by entrepreneurs of Cleantech companies. Entrepreneurs from 12 Cleantech (Clean Technology) companies in the Brazilian energy sector were interviewed, using a qualitative research approach. Big Data & Data Analytics, Internet of Things and Artificial Intelligence were identified as digital technologies enablers of a sustainable energy transition for the sector. The study presents the relation and behavior of each technology with the sustainability triple bottom line and introduces a framework on how digital solutions contribute to solving the main bottlenecks in the electricity sector in a sustainable way. Research shown that Cleantechs also operationalize digital technologies like Blockchain and 5G to enable energy transformation as it has emerged as research findings. Additionally, technology and digitalization in conjunction with entrepreneur's capacity for innovation are driving mechanisms for companies in the initial stage of the energy sector, exploring regulatory loopholes and putting their business models into practice.Este artigo tem como objetivo mapear as principais soluções digitais praticadas por empresários de empresas de tecnologia limpa. Foram entrevistados empresários de 12 empresas de tecnologia limpa (Cleantech) do setor de energia brasileiro, por meio de uma abordagem de pesquisa qualitativa. Big Data & Data Analytics, Internet das Coisas e a Inteligência Artificial foram identificadas como facilitadores das tecnologias digitais de uma transição energética sustentável para o setor. O estudo apresenta a relação e o comportamento de cada tecnologia com o triple bottom line da sustentabilidade e apresenta um quadro de como as soluções digitais contribuem para resolver os principais gargalos do setor elétrico de forma sustentável. A pesquisa mostra que as Cleantechs também operacionalizam tecnologias digitais como Blockchain e 5G para permitir a transformação de energia conforme emergiu como resultados de pesquisa. Além disso, a tecnologia e a digitalização em conjunto com a capacidade de inovação do empreendedor são mecanismos motrizes para empresas em estágio inicial do setor de energia, explorando brechas regulatórias e colocando em prática seus modelos de negócios

Cell sources of inflammatory mediators present in bone marrow areas inside the meniscus

Copyright: © 2019 Rocha et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Purpose: To demonstrate the production of inflammatory mediators by cells located in bone marrow spaces inside rodent menisci. Methods: Mice subjected to transection of the medial collateral and anterior cruciate ligaments and meniscotomy (osteoarthritis model) or to a sham procedure, as well as non-operated (naive) mice and rats, had knee joints excised. Tissues were stained with hematoxylin-eosin and tartrate-resistant acid phosphatase (TRAP). CD68+ cells, inducible nitric oxide synthase (iNOS), interleukin (IL)-1β, and tumor necrosis factor (TNF) expression were detected using immunohistochemistry. Results: Lamellar ossified areas, bone-entrapped osteocytes and bone marrow spaces were found inside menisci of one week up to 6 months-old naïve mice, regardless of gender. Menisci from naive rats also showed the same pattern with bone marrow areas. CD68+ cells were identified in bone marrow areas inside the meniscus of mice. TRAP+ osteoclasts, and hematogenous precursors expressing IL-1β, TNF, and iNOS were identified inside bone marrow areas in meniscal samples from both naïve and sham operated mice. Quantitative immunoexpression of IL-1 β, TNF and iNOS was more intense, P = 0.0194, 0.0293, 0.0124, respectively, in mouse knees from mice sacrificed 49 days after being subjected to an osteoarthritis (OA) model as compared to sham operated animals. Conclusion: We provide novel data showing that rodent menisci display bone marrow areas with cells able to produce inflammatory mediators. Immunoexpression of inflammatory mediators in those bone marrow areas is significantly more pronounced in mice subjected to experimental OA.The study was funded by: UID/BIM/50005/2019, project funded by Fundação para a Ciência e a Tecnologia (FCT)/ Ministério da Ciência, Tecnologia e Ensino Superior (MCTES) through Fundos do Orçamento de Estado.info:eu-repo/semantics/publishedVersio

Clinical treatment of resistant epilepsy

The authors analysed 34 cases of resistant epilepsy (20 males and 14 females, mean age 23 years), treated clinically between February/1984 and May/1986. The patients underwent neurological, neuropsychological, psychological, psychiatric, cerebrospinal fluid, electroencephalographic, tomographic and/or angiographic examination. Most of the patients had complex partial seizures. The etiology was unknown in 19 patients (55.8%), probable neurocysticercosis in 6, perinatal hypoxia in 5, delivery trauma in 3 and probable sequelae of encephalitis in 2 patients. There was a clear past history of infantile febrile convulsion in 2 patients. Most patients received carbamazepine (mean dose 24.5 mg/kg/day), phenytoin (5 mg/kg and valproic acid (28 mg/kg) as monotherapy or in association. Twenty-two patients (64.7%) had more than 80% decrease of the seizure frequency. Nine resistant epilepsy-cases (24.5%) were evaluated as candidates for surgical therapy. The authors concluded that the resistant epilepsy is best managed by a specialised, multidisciplinary team, and pointed out the need of a correct diagnosis of the seizure type, an adequate drug therapy and a good engagement of the patient and his family in the treatment.Foram estudados 34 casos de epilepsia de difícil controle, encaminhados ao Grupo de Trabalho de Epilepsia (GTE) do Instituto de Neurologia de Goiânia de 1984 a 1986. Todos eram submetidos a reavaliação neurológica. Vinte e três dos 34 pacientes tinham crises parciais complexas. A maioria foi tratada com carbamazepina, difenil-hidantoína e ácido valpróico, em forma monoterápica ou associada entre si. Obteve-se redução de mais de 80% da freqüência das crises em 22 pacientes (64,7%), além de leve melhora da qualidade de vida. Os autores concluem sobre as vantagens de uma equipe especializada, multidisciplinar, na abordagem da epilepsia rebelde e ressaltam a necessidade de: a. um correto diagnóstico das crises, seguido do uso da medicação apropriada, por tempo suficiente (mínimo de 0 meses) e em dose adequada (até a dose máxima tolerável), abandonando-a só depois do controle de sua concentração sérica; b. um bom engajamento do paciente e de sua família no tratamento.35135

Comparison with adult-onset rheumatic diseases

Objective To compare physical disability, mental health, fatigue and health-related quality of life (HRQoL) across juvenile idiopathic arthritis (JIA) categories in adulthood and between JIA and adult-onset rheumatic diseases. Methods Cross-sectional analysis nested in a cohort of adult patients with JIA registered in the Rheumatic Diseases Portuguese Register (Reuma.pt). Physical disability (Health Assessment Questionnaire - Disability Index), mental health symptoms (Hospital Anxiety and Depression Scale), fatigue (Functional Assessment of Chronic Illness Therapy - Fatigue Scale (FACIT-F)) and HRQoL (EuroQol-5D (EQ5D) and Short Form (SF-36)) were compared across JIA categories. Patients with polyarticular JIA and enthesis-related arthritis (ERA) JIA were compared respectively to patients with rheumatoid arthritis (RA) and spondyloarthritis (SpA), matched for gender and age, adjusted for disease duration and activity. Results 585 adult patients with JIA were included. Comparison across JIA categories showed that persistent oligoarthritis and patients with ERA reported a higher score in EQ5D and SF-36 physical component when compared with other JIA categories. Polyarticular JIA reported less disability and fatigue than patients with RA (median Health Assessment Questionnaire of 0.25 vs 0.63; p<0.001 and median FACIT-F score 42 vs 40; p=0.041). Polyarticular JIA had also better scores on EQ5D and all domains of SF-36, than patients with RA. Patients with ERA reported less depression and anxiety symptoms (0% vs 14.8%; p=0.003% and 9% vs 21.3%; p=0.002) and less fatigue symptoms (45 vs 41; p=0.01) than patients with SpA. Conclusion Persistent oligoarticular JIA and ERA are the JIA categories in adulthood with better HRQoL. Overall, adult polyarticular and patients with ERA JIA have lower functional impairment and better quality-of-life than patients with RA and SpA.publishersversionpublishe

A COVID-19 outbreak in a rheumatology department upon the early days of the pandemic

Copyright © 2020 Cascão, Vidal, Carvalho, Lopes, Romão, Goncalves, Moita andFonseca. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.Objectives: To describe our experience with a coronavirus disease 2019 (COVID-19) outbreak within a large rheumatology department early in the pandemic. Methods: Symptomatic and asymptomatic healthcare workers (HCWs) had a naso-oropharyngeal swab for detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and were followed clinically. Reverse transcription polymerase-chain reaction (RT-PCR) was repeated to document cure, and serological response was assessed. Patients with risk contacts within the department in the 14 days preceding the outbreak were screened for COVID-19 symptoms. Results: 14/34 HCWs (41%; 40 ± 14 years, 71% female) tested positive for SARS-CoV-2, and 11/34 (32%) developed symptoms but were RT-PCR-negative. Half of RT-PCR-positive HCWs did not report fever, cough, or dyspnea before testing, which were absent in 3/14 cases (21%). Mild disease prevailed (79%), but 3 HCWs had moderate disease requiring further assessment, which excluded severe complications. Nevertheless, symptom duration (28 ± 18 days), viral shedding (31 ± 10 days post-symptom onset, range 15-51), and work absence (29 ± 28 days) were prolonged. 13/14 (93%) of RT-PCR-positive and none of the RT-PCR-negative HCWs had a positive humoral response Higher IgG indexes were observed in individuals over 50 years of age (14.5 ± 7.7 vs. 5.0 ± 4.4, p = 0.012). Of 617 rheumatic patients, 8 (1.3%) developed COVID-19 symptoms (1/8 hospitalization, 8/8 complete recovery), following a consultation/procedure with an asymptomatic (7/8) or mildly symptomatic (1/8) HCW. Conclusions: A COVID-19 outbreak can occur among HCWs and rheumatic patients, swiftly spreading over the presymptomatic stage. Mild disease without typical symptoms should be recognized and may evolve with delayed viral shedding, prolonged recovery, and adequate immune response in most individuals.info:eu-repo/semantics/publishedVersio

a Portuguese and Brazilian collaborative analysis

OBJECTIVE: To investigate the relationship between body mass index (BMI) and disease activity in patients with Juvenile Idiopathic Arthritis (JIA). METHODS: Patients with JIA, aged ≤18 years, registered at the Rheumatic Diseases Portuguese Register (Reuma.pt) in Portugal and Brazil were included. Age- and sex-specific BMI percentiles were calculated based on WHO growth standard charts and categorized into underweight (P 97). Disease activity was assessed by Juvenile Arthritis Disease Activity Score (JADAS-27). Uni- and multivariate analyses were performed. RESULTS: A total of 275 patients were included. The prevalence of underweight, normal weight, overweight and obesity was 6.9%, 67.3%, 15.3% and 10.5%, respectively. Underweight patients had significantly higher number of active joints (p <0.001), patient's/parent's global assessment of disease activity (PGA) (p=0.020), physician's global assessment of disease activity (PhGA) (p <0.001), erythrocyte sedimentation rate (ESR) (p=0.032) and overall higher JADAS-27 (p <0.001), compared to patients with normal weight, overweight and obesity. In the multivariate regression, underweight persisted significantly associated with higher disease activity, compared to normal weight (B=-9.430, p <0.001), overweight (B=-9.295, p=0.001) and obesity (B=-9.120, p=0.001), when adjusted for age, gender, country, ethnicity, JIA category and therapies used. The diagnosis of RF- (B=3.653, p=0.006) or RF+ polyarticular JIA (B=5.287, p=0.024), the absence of DMARD therapy (B=5.542, p <0.001) and the use of oral GC (B=4.984, p=0.002) were also associated with higher JADAS-27. CONCLUSION: We found an independent association between underweight and higher disease activity in patients with JIA. Further studies are needed to understand the underlying mechanisms of this association.publishersversionpublishe