Work Culture of Tsanawiyah Madrasah During COVID-19 in Bandar Lampung City

A Madrasa’s work culture values can influence not only emotional involvement, normative involvement, and job satisfaction, but also physical, emotional, and cognitive participation in the workplace. The purpose of this study was to determine and analyze the implementation of the 5 values of work culture at the Madrasah Tsanawiyah in Bandar Lampung. This research method is descriptive and qualitative in nature, and collects primary and secondary data using observation, interviews, and documentation. Upon collection, data analysis was carried out by reducing, displaying, and verifying the data so that it could be concluded at the end of the analysis. The research locations are as follows: Madrasah Tsanawiyah 1 Bandar Lampung, Madrasah Tsanawiyah 2 Bandar Lampung, Madrasah Tsanawiyah Muhammadiyah, and Private Madrasah Tsanawiyah in Bandar Lampung. The results explain that the implementation of a work culture by the Ministry of Religion is successful in Madrasah Tsanawiyah 1, Bandar Lampung. The Madrasah Tsanawiyah private schools in Bandar Lampung City are not yet optimal and will be improved. The success of implementing the teacher’s example must be carried out in collaboration between the school and parents, because parents are the main figures in the formation of their children’s character, and children will therefore act according to the examples applied during the COVID-19 pandemic. Keywords: Madrasah Tsanawiyah, Pandemic COVID-19, Work Cultur

Strengthening Local Wisdom-Based Work Culture in Improving the Quality of Education in Madrasah

This study aimed to improve the quality of madrasah education by strengthening the work culture of Madrasah Aliyah teachers in the western region of the Central Lampung district. This research uses a qualitative case study approach. Data collection techniques used are observation, interviews, and documentation. The data analysis technique uses Miles and Huberman's interactive analysis, which includes; the process of data collection, data reduction, data presentation, and conclusion. The results showed that improving the quality of madrasah education through strengthening the work culture of Madrasah Aliyah teachers was carried out through the implementation of work culture in planning, work culture in organizing, work culture in performance, and work culture in supervision, work culture in evaluation. This research has implications for the importance of a work culture that must be managed in such a way as to achieve the desired goals

Mathematical Model as a Tool for the Control of Vector-Borne Diseases: Wolbachia Example

Dengue is a vector-borne disease that risks two-thirds of the world’s population particularly in tropical and subtropical regions. Strategies have been implemented, but they are only effective in the short term. A new innovative and promising strategy against dengue is by the use of Wolbachia bacterium. This requires that Wolbachia-carrying mosquitoes should persist in the population. To assess the persistence of Wolbachia-carrying mosquitoes and its effects on dengue, a number of mathematical models have been formulated and analysed. In this chapter, we review the existing mathematical models of Wolbachia-carrying mosquito population dynamics and dengue with Wolbachia intervention and provide examples of the mathematical models. Simulations of the models are presented to illustrate the model’s solutions

Saat Parasit Membasmi Parasit: Uji Efektivitas Ekstrak Benalu Sebagai Terapi Malaria Baru

Nowadays, the antimalarial drug used showed resistances. Scientists look for new drugs by research especially using herbal plans. The mistletoe(Dendrophthoe pentandra) is previously known having antimalarial activity. This study was conducted to determine in vitro antiplasmodial activity, mechanism of heme polymerase inhibition, and cytotoxicity of water and ethanol extracts of Dendrophthoe pentandra against Vero cells.The results showed that water and ethanol extract of Dendrophthoe pentandra has in vitro antiplasmodial activity, inhibition of polymerase heme, and cytotoxic effect on Vero cells with IC50 values.It can be concluded that Dendrophthoe pentandra has potency as an antiplasmodial.Keywords :Dendrophthoe pentandra, antiplasmodium, heme polymerase, cytotoxic, Vero cel

Uji Aktivitas Antiplasmodium Ekstrak Benalu Secara in Vivo Pada Mencit Galur Swiss

Malaria is one of the most prevalent tropical disease in the world. Until now, the use of antimalarials in malaria patients generated a lot of resistance so many scientists began the development of research using herbal plant ingredients, for example mistletoe (Dendrophthoe pentandra) This study was conducted to determine the effect of antiplasmodium in vivo. Antiplasmodium test conducted on P. berghei which were injected into mice suppression method. The results show that the Dendrophthoe pentandra extract has antiplasmodium activity with ED50 of 146,2 mg/kgBW. It can be concluded that Dendrophthoe pentandra has the potential as an antimalarial agent in vivo

Comprehensive Gene and microRNA Expression Profiling Reveals a Role for microRNAs in Human Liver Development

BACKGROUND AND AIMS: microRNAs (miRNAs) are small noncoding RNAs that regulate cognate mRNAs post-transcriptionally. miRNAs have been implicated in regulating gene expression in embryonic developmental processes, including proliferation and differentiation. The liver is a multifunctional organ, which undergoes rapid changes during the developmental period and relies on tightly-regulated gene expression. Little is known regarding the complex expression patterns of both mRNAs and miRNAs during the early stages of human liver development, and the role of miRNAs in the regulation of this process has not been studied. The aim of this work was to study the impact of miRNAs on gene expression during early human liver development. METHODS: Global gene and miRNA expression were profiled in adult and in 9-12w human embryonic livers, using high-density microarrays and quantitative RT-PCR. RESULTS: Embryonic liver samples exhibited a gene expression profile that differentiated upon progression in the developmental process, and revealed multiple regulated genes. miRNA expression profiling revealed four major expression patterns that correlated with the known function of regulated miRNAs. Comparison of the expression of the most regulated miRNAs to that of their putative targets using a novel algorithm revealed a significant anti-correlation for several miRNAs, and identified the most active miRNAs in embryonic and in adult liver. Furthermore, our algorithm facilitated the identification of TGFbeta-R1 as a novel target gene of let-7. CONCLUSIONS: Our results uncover multiple regulated miRNAs and genes throughout human liver development, and our algorithm assists in identification of novel miRNA targets with potential roles in liver development

What information and the extent of information research participants need in informed consent forms: a multi-country survey

Background: The use of lengthy, detailed, and complex informed consent forms (ICFs) is of paramount concern in biomedical research as it may not truly promote the rights and interests of research participants. The extent of information in ICFs has been the subject of debates for decades; however, no clear guidance is given. Thus, the objective of this study was to determine the perspectives of research participants about the type and extent of information they need when they are invited to participate in biomedical research. Methods: This multi-center, cross-sectional, descriptive survey was conducted at 54 study sites in seven Asia-Pacific countries. A modified Likert-scale questionnaire was used to determine the importance of each element in the ICF among research participants of a biomedical study, with an anchored rating scale from 1 (not important) to 5 (very important). Results: Of the 2484 questionnaires distributed, 2113 (85.1%) were returned. The majority of respondents considered most elements required in the ICF to be \u27moderately important\u27 to \u27very important\u27 for their decision making (mean score, ranging from 3.58 to 4.47). Major foreseeable risk, direct benefit, and common adverse effects of the intervention were considered to be of most concerned elements in the ICF (mean score = 4.47, 4.47, and 4.45, respectively). Conclusions: Research participants would like to be informed of the ICF elements required by ethical guidelines and regulations; however, the importance of each element varied, e.g., risk and benefit associated with research participants were considered to be more important than the general nature or technical details of research. Using a participant-oriented approach by providing more details of the participant-interested elements while avoiding unnecessarily lengthy details of other less important elements would enhance the quality of the ICF