Analysis of Risks Associated with Hazardous Materials Transportation in the French Chemical Industry

This article focuses on the risks associated with Hazardous Materials Transportation (HazMaT) events in the French chemical industry between 1981 and 2022. The study aims to analyze and assess the causes and consequences of past events using the ARIA database, which lists over 54,000 events that have taken place in France and abroad. The severity of events is classified into five categories, from near misses to catastrophic events. The study highlights the importance of risk analysis/assessment and lessons learned from past events in managing natural and technological risks

Hotspots of land use change in Europe

Die Zweitveröffentlichung der Publikation wurde durch Studierende des Projektseminars "Open Access Publizieren an der HU" im Sommersemester 2017 betreut. Nachgenutzt gemäß den CC-Bestimmungen des Lizenzgebers bzw. einer im Dokument selbst enthaltenen CC-Lizenz.Assessing changes in the extent and management intensity of land use is crucial to understanding land-system dynamics and their environmental and social outcomes. Yet, changes in the spatial patterns of land management intensity, and thus how they might relate to changes in the extent of land uses, remains unclear for many world regions.Wecompiled and analyzed high-resolution, spatiallyexplicit land-use change indicators capturing changes in both the extent and management intensity of cropland, grazing land, forests, and urban areas for all of Europe for the period 1990–2006. Based on these indicators, we identified hotspots of change and explored the spatial concordance of area versus intensity changes.Wefound a clear East–West divide with regard to agriculture, with stronger cropland declines and lower management intensity in the East compared to the West. Yet, these patterns were not uniform and diverging patterns of intensification in areas highly suitable for farming, and disintensification and cropland contraction in more marginal areas emerged. Despite the moderate overall rates of change, many regions in Europe fell into at least one land-use change hotspot during 1990–2006, often related to a spatial reorganization of land use (i.e., co-occurring area decline and intensification or co-occurring area increase and disintensification). Our analyses highlighted the diverse spatial patterns and heterogeneity of land-use changes in Europe, and the importance of jointly considering changes in the extent and management intensity of land use, as well as feedbacks among land-use sectors. Given this spatial differentiation of land-use change, and thus its environmental impacts, spatially-explicit assessments of land-use dynamics are important for context-specific, regionalized land-use policy making.Peer Reviewe

CYGNSS Ocean Altimetry: A Status Report

Comunicación expuesta online en el CYGNSS Science Team Summer Meeting celebrado del 27 al 29 de julio de 202

Ventilation of the Arabian Sea Oxygen Minimum Zone by Persian Gulf Water

Dense overflows from marginal seas are critical pathways of oxygen supply to the Arabian Sea oxygen minimum zone (OMZ), yet these remain inadequately understood. Climate models struggle to accurately reproduce the observed extent and intensity of the Arabian Sea OMZ due to their limited ability to capture processes smaller than their grid scale, such as dense overflows. Multi-month repeated sections by underwater gliders off the coast of Oman resolve the contribution of dense Persian Gulf Water (PGW) outflow to oxygen supply within the Arabian Sea OMZ. We characterize PGW properties, seasonality, transport and mixing mechanisms to explain local processes influencing water mass transformation and oxygen fluxes into the OMZ. Atmospheric forcing at the source region and eddy mesoscale activity in the Gulf of Oman control spatiotemporal variability of PGW as it flows along-shelf off the northern Omani coast. Subseasonally, it is modulated by stirring and shear-driven mixing driven by eddy-topography interactions. The oxygen transport from PGW to the OMZ is estimated to be 1.3 Tmol yr−1 over the observational period, with dramatic inter- and intra-annual variability (±1.6 Tmol yr−1). We show that this oxygen is supplied to the interior of the OMZ through the combined action of double-diffusive and shear-driven mixing. Intermittent shear-driven mixing enhances double-diffusive processes, with mechanical shear conditions (Ri < 0.25) prevailing 14% of the time at the oxycline. These findings enhance our understanding of fine-scale processes influencing oxygen dynamics within the OMZ that can provide insights for improved modeling and prediction efforts

Current status of the IAG working group 4.3.7 on geodetic GNSS-R

Presentación realizada online en el Scientific Assembly of the International Association of Geodesy (2021) celebrado del 28 de junio al 2 de julio en Beijing

An Introduction to the HydroGNSS GNSS Reflectometry Remote Sensing Mission

HydroGNSS (Hydrology using Global Navigation Satellite System reflections) has been selected as the second European Space Agency (ESA) Scout earth observation mission to demonstrate the capability of small satellites to deliver science. This article summarizes the case for HydroGNSS as developed during its system consolidation study. HydroGNSS is a high-value dual small satellite mission, which will prove new concepts and offer timely climate observations that supplement and complement the existing observations and are high in ESAs earth observation scientific priorities. The mission delivers the observations of four hydrological essential climate variables as defined by the global climate observing system using the new technique of GNSS reflectometry. These will cover the world&#x0027;s land mass to 25 km resolution, with a 15-day revisit. The variables are soil moisture, inundation or wetlands, freeze&#x002F;thaw state, and above-ground biomass

Caspase-activated DNase is necessary and sufficient for oligonucleosomal DNA breakdown, but not for chromatin disassembly during caspase-dependent apoptosis of LN-18 glioblastoma cells

Altres ajuts: FPU MICINN, MEC programa Ramón y CajalCaspase-dependent apoptosis is a controlled type of cell death characterized by oligonucleosomal DNA breakdown and major nuclear morphological alterations. Other kinds of cell death do not share these highly distinctive traits because caspase-activated DNase (DFF40/CAD) remains inactive. Here, we report that human glioblastoma multiforme-derived LN-18 cells do not hydrolyze DNA into oligonucleosomal fragments after apoptotic insult. Furthermore, their chromatin remains packaged into a single mass, with no signs of nuclear fragmentation. However, ultrastructural analysis reveals that nuclear disassembly occurs, although compacted chromatin does not localize into apoptotic nuclear bodies. Caspases become properly activated, and ICAD, the inhibitor of DFF40/CAD, is correctly processed. Using cell-free in vitro assays, we show that chromatin from isolated nuclei of LN-18 cells is suitable for hydrolysis into oligonuclesomal fragments by staurosporine-pretreated SH-SY5Y cytoplasms. However, staurosporine-pretreated LN-18 cytoplasms do not induce DNA laddering in isolated nuclei from either LN-18 or SH-SY5Y cells because LN-18 cells express lower amounts of DFF40/CAD. DFF40/CAD overexpression makes LN-18 cells fully competent to degrade their DNA into oligonucleosome-sized fragments, and yet they remain unable to arrange their chromatin into nuclear clumps after apoptotic insult. Indeed, isolated nuclei from LN-18 cells were resistant to undergoing apoptotic nuclear morphology in vitro. The use of LN-18 cells has uncovered a previously unsuspected cellular model, whereby a caspase-dependent chromatin package is DFF40/CAD-independent, and DFF40/CAD-mediated double-strand DNA fragmentation does not warrant the distribution of the chromatin into apoptotic nuclear bodies. The studies highlight a not-yet reported DFF40/CAD-independent mechanism driving conformational nuclear changes during caspase-dependent cell death

Innovative sea surface monitoring with GNSS-REflectometry aboard ISS: overview and recent results from GEROS-ISS

GEROS-ISS (GEROS hereafter) stands for GNSS REflectometry, Radio Occultation and Scatterometry onboard the International Space Station. It is a scientific experiment, proposed to the European Space Agency (ESA) in 2011 for installation aboard the ISS. The main focus of GEROS is the dedicated use of signals from the currently available Global Navigation Satellite Systems (GNSS) for remote sensing of the System Earth with focus to Climate Change characterisation. The GEROS mission idea and the current status are briefly reviewed.Peer ReviewedPostprint (author's final draft

IEEE 4003-2021

27 páginasThe scope of this effort is to develop a standard for data and metadata content arising from spaceborne global navigation satellite system-reflectometry (GNSS-R) missions, which uses GNSS signals as signals of opportunity, as described in “The IEEE SA Working Group on Spaceborne GNSS-R: Scene Study.” In particular, this standard would provide a means for describing: a) The terminology assigned to GNSS-R data and products, such as the product levels. b) The structure and content of the data. This includes, but is not limited to, units of measure, data organization, data description, data encoding, and data storage format. c) The metadata. This includes and is not limited to metadata, methods and algorithms applied to the data, parameters related to the algorithms, citation information, instrument calibration and characterization, and description of the input signals. The purpose of this standard is to provide a set of specifications and recommended practices that can be used to describe any known and future spaceborne GNSS-R data set, allowing users to work with different GNSS-R data sets at the same time. The definition of such standard would also allow any software that uses these data to fully operate and ingest any spaceborne GNSS-R input data as they will conform to the same standard