921 research outputs found
Temperature variability of the Iberian Range since 1602 inferred from tree-ring records
Tree rings are an important proxy to understand the natural drivers of climate variability in the Mediterranean Basin and hence to improve future climate scenarios in a vulnerable region. Here, we compile 316 treering width series from 11 conifer sites in the western Iberian Range. We apply a new standardization method based on the trunk basal area instead of the tree cambial age to develop a regional chronology which preserves high to low-frequency variability. A new reconstruction for the 1602–2012 period correlates at ??0.78 with observational September temperatures with a cumulative mean of the 21 previous months over the 1945– 2012 calibration period. The new IR2Tmax reconstruction is spatially representative for the Iberian Peninsula and captures the full range of past Iberian Range temperature variability. Reconstructed longterm temperature variations match reasonably well with solar irradiance changes since warm and cold phases correspond with high and low solar activity, respectively. In addition, some annual temperature downturns coincide with volcanic eruptions with a 3-year lag
Temperature variability in the Iberian Range since 1602 inferred from tree-ring records
Tree rings are an important proxy to understand the natural drivers of climate variability in the Mediterranean Basin and hence to improve future climate scenarios in a vulnerable region. Here, we compile 316 tree-ring width series from 11 conifer sites in the western Iberian Range. We apply a new standardization method based on the trunk basal area instead of the tree cambial age to develop a regional chronology which preserves high- to low-frequency variability. A new reconstruction for the 1602-2012 period correlates at g''0.78 with observational September temperatures with a cumulative mean of the 21 previous months over the 1945-2012 calibration period. The new IR2Tmax reconstruction is spatially representative for the Iberian Peninsula and captures the full range of past Iberian Range temperature variability. Reconstructed long-term temperature variations match reasonably well with solar irradiance changes since warm and cold phases correspond with high and low solar activity, respectively. In addition, some annual temperature downturns coincide with volcanic eruptions with a 3-year lag
Tree-ring-based drought reconstruction in the Iberian Range (east of Spain) since 1694
Droughts are a recurrent phenomenon in the Mediterranean basin with negative consequences for society, economic activities, and natural systems. Nevertheless, the study of drought recurrence and severity in Spain has been limited so far due to the relatively short instrumental period. In this work, we present a reconstruction of the standardized precipitation index (SPI) for the Iberian Range. Growth variations and climatic signals within the network are assessed developing a correlation matrix and the data combined to a single chronology integrating 336 samples from 169 trees of five different pine species distributed throughout the province of Teruel. The new chronology, calibrated against regional instrumental climatic data, shows a high and stable correlation with the July SPI integrating moisture conditions over 12 months forming the basis for a 318-year drought reconstruction. The climate signal contained in this reconstruction is highly significant (p < 0.05) and spatially robust over the interior areas of Spain located above 1000 meters above sea level (masl). According to our SPI reconstruction, seven substantially dry and five wet periods are identified since the late seventeenth century considering =±1.76 standard deviations. Besides these, 36 drought and 28 pluvial years were identified. Some of these years, such as 1725, 1741, 1803, and 1879, are also revealed in other drought reconstructions in Romania and Turkey, suggesting that coherent larger-scale synoptic patterns drove these extreme deviations. Since regional drought deviations are also retained in historical documents, the tree-ring-based reconstruction presented here will allow us to cross-validate drought frequency and magnitude in a highly vulnerable region
Summer drought reconstruction in Northeastern Spain inferred from a tree-ring latewood network since 1734
Drought recurrence in the Mediterranean is regarded as a fundamental factor for socioeconomic development and the resilience of natural systems in context of global change. However, knowledge of past droughts has been hampered by the absence of high-resolution proxies. We present a drought reconstruction for the northeast of the Iberian Peninsula based on a new dendrochronology network considering the Standardized Evapotranspiration Precipitation Index (SPEI). A total of 774 latewood width series from 387 trees of P. sylvestris and P. uncinata was combined in an interregional chronology. The new chronology, calibrated against gridded climate data, reveals a robust relationship with the SPEI representing drought conditions of July and August. We developed a summer drought reconstruction for the period 1734– 2013 representative for the northeastern and central Iberian Peninsula. We identified 16 extremely dry and 17 extremely wet summers and four decadal scale dry and wet periods, including 2003–2013 as the driest episode of the reconstruction
A new archive of large volcanic events over the past millennium derived from reconstructed summer temperatures
Information about past volcanic impact on climate is mostly derived from historic documentary data and sulfate depositions in polar ice sheets. Although these archives have provided important insights into the Earth's volcanic eruption history, the climate forcing and exact dating of many events is still vague. Here we apply a new method of break detection to the first millennium-length maximum latewood density reconstruction of Northern Hemisphere summer temperatures to develop an alternative record of large volcanic eruptions. The analysis returns fourteen outstanding cooling events, all of which agree well with recently developed volcanic forcing records from high-resolution bipolar ice cores. In some cases, however, the climatic impact detected with our new method peaks in neighboring years, likely due to either dating errors in the polar ice cores or uncertainty in the interpretation of atmospheric aerosol transport to polar ice core locations. The most apparent mismatches between forcing and cooling estimates occur in the 1450s and 1690s. Application of the algorithm to two additional and recently developed reconstructions that blend maximum latewood density and ring width data reproduces twelve of the detected events among which eight are retrieved in all three of the dendroclimatic reconstructions. Collectively, the new estimates of volcanic activity with precise age control provide independent evidence for forcing records during the last millennium. Evaluating the cooling magnitude in response to detected events yields an upper benchmark for the volcanic impact on climate. The average response to the ten major events in the density derived reconstruction is −0.60 °C ± 0.13 °C. Other last millennium temperature records from proxies and model simulations reveal higher cooling estimates, which is, to some degree, related to the very different high frequency variance in these timeseries
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High-resolution temperature variability reconstructed from black pine tree ring densities in Southern Spain
The presence of an ancient, high-elevation pine forest in the Natural Park of Sierras de Cazorla in southern Spain, including some trees reaching >700 years, stimulated efforts to develop high-resolution temperature reconstructions in an otherwise drought-dominated region. Here, we present a reconstruction of spring and fall temperature variability derived from black pine tree ring maximum densities reaching back to 1350 Coefficient of Efficiency (CE). The reconstruction is accompanied by large uncertainties resulting from low interseries correlations among the single trees and a limited number of reliable instrumental stations in the study region. The reconstructed temperature history reveals warm conditions during the early 16th and 19th centuries that were of similar magnitude to the warm temperatures recorded since the late 20th century. A sharp transition from cold conditions in the late 18th century (t1781–1810 = −1.15 °C ± 0.64 °C) to warm conditions in the early 19th century (t1818–1847 = −0.06 °C ± 0.49 °C) is centered around the 1815 Tambora eruption (t1816 = −2.1 °C ± 0.55 °C). The new reconstruction from southern Spain correlates significantly with high-resolution temperature histories from the Pyrenees located ~600 km north of the Cazorla Natural Park, an association that is temporally stable over the past 650 years (r1350–2005 > 0.3, p < 0.0001) and particularly strong in the high-frequency domain (rHF > 0.4). Yet, only a few of the reconstructed cold extremes (1453, 1601, 1816) coincide with large volcanic eruptions, suggesting that the severe cooling events in southern Spain are controlled by internal dynamics rather than external (volcanic) forcing.</jats:p
Because scientists are unable to explain the unexplained, screening for cardiovascular abnormalities is a good method to protect against sudden unexpected death in patients with epilepsy
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Universidade Federal de São Paulo (UNIFESP) Escola Paulista de MedicinaUniversidade Federal de São Paulo (UNIFESP) Departamento de FisiologiaUniversidade de São Paulo Faculdade de Medicina Hospital das ClínicasUNIFESP, EPMUNIFESP, Depto. de FisiologiaSciEL
Lactate Dehydrogenase-Elevating Virus Induces Systemic Lymphocyte Activation via TLR7-Dependent IFNα Responses by Plasmacytoid Dendritic Cells
BACKGROUND:Lactate dehydrogenase-elevating virus (LDV) is a natural infectious agent of mice. Like several other viruses, LDV causes widespread and very rapid but transient activation of both B cells and T cells in lymphoid tissues and the blood. The mechanism of this activation has not been fully described and is the focus of the current studies. PRINCIPAL FINDINGS:A known inducer of early lymphocyte activation is IFNalpha, a cytokine strongly induced by LDV infection. Neutralization of IFNalpha in the plasma from infected mice ablated its ability to activate lymphocytes in vitro. Since the primary source of virus-induced IFNalpha in vivo is often plasmacytoid dendritic cells (pDC's), we depleted these cells prior to LDV infection and tested for lymphocyte activation. Depletion of pDC's in vivo eradicated both the LDV-induced IFNalpha response and lymphocyte activation. A primary receptor in pDC's for single stranded RNA viruses such as LDV is the toll-like receptor 7 (TLR7) pattern recognition receptor. Infection of TLR7-knockout mice revealed that both the IFNalpha response and lymphocyte activation were dependent on TLR7 signaling in vivo. Interestingly, virus levels in both TLR7 knockout mice and pDC-depleted mice were indistinguishable from controls indicating that LDV is largely resistant to the systemic IFNalpha response. CONCLUSION:Results indicate that LDV-induced activation of lymphocytes is due to recognition of LDV nucleic acid by TLR7 pattern recognition receptors in pDC's that respond with a lymphocyte-inducing IFNalpha response
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