Implementasi Algoritma WASPAS pada Sistem Rekomendasi Pemilihan Anime Berbasis Web

Anime adalah sebuah kata serapan dalam bahasa Jepang dari kata "animasi", sebuah metode untuk memanipulasi gambar sehingga gambar tersebut tampak bergerak. Anime juga berkembang sangat pesat saat ini diberbagai belahan dunia termasuk juga Indonesia. Anime seperti film memiliki banyak judul anime, maka diperlukan sistem rekomendasi untuk membantu orang untuk memilah anime menjadi lebih sempit untuk memudah orang untuk memilih anime kesukaan mereka. Metode Weighted Aggregated Sum Product Assessment (WASPAS) dapat membantu orang dalam memilih anime dengan peringkat untuk memberitahu anime terbaik saat ini. Sistem ini yang diaplikasikan kedalam website dengan Bahasa pemrograman PHP dan framework Laravel untuk bisa divisualisasikan supaya user lebih tertarik menggunakan dan bisa diakses dimana saja. Hasil penelitian menunjukan kesuksesan aplikasi 82.91% sehingga menujukan bahwa aplikasi website "Rekomendasi Pemilihan Anime" reliable berdasarkan dari jawaban responden

Rancang Bangun Sistem Kehadiran Berbasis Web PT. Ekasaudara Jaya

Seiring dengan perkembangan teknologi, semakin banyak proses-proses dan kegiatan manual yang dikomputerisasikan, salah satunya adalah pengambilan presensi pegawai. Perubahan serupa juga dilakukan oleh perusahaan PT. Ekasaudara jaya dimana penulis melakukan kerja magang. Dalam laporan kerja magang ini dijelaskan pengerjaan sistem presensi pegawai sebagai bentuk kerja magang penulis pada PT. EKASUDARA JAYA. Sistem presensi yang dibangun ini berbasiskan web dengan menggunakan HTML, Xampp, beserta bahasa pemograman PHP dan database MySQL

Ultra-energy-efficient Silicon Photonic Modulators Driven by Transparent Conductive Oxides

Silicon photonics has become the most promising platform for future large-scale optical interconnect and optical computing systems due to its inherent CMOS compatibility, which brings exclusive advantages in bandwidth density, energy efficiency, and cost effectiveness. Parallel optical interconnects based on photonic integrated circuits (PICs) have the capacity to meet the high bandwidth density requirement of parallel computing systems, however, are facing the same challenge in energy efficiency and bandwidth limit as their electrical counterparts because the margin shrinks unfavorably for shorter distance optical interconnects. Unprecedented requirement in energy efficiency has been outlined, which poses tremendous challenges to existing PIC devices, even to the state-of-the-arts silicon photonics. In recent years, transparent conductive oxides (TCOs) have emerged as increasingly favorable tunable materials for active photonic devices. TCOs exhibit a large refractive index tunability on the order of unity, which enables unique epsilon-near-zero (ENZ) light confinement and significant enhancement in light-matter interaction. These intriguing optical properties offer us the potential to expand the functionality and improve the device performance of the silicon photonics platform. This dissertation presents design and demonstration of novel active photonic devices driven by TCOs on silicon photonics platform, with a focus on achieving ultra-energy-efficient silicon photonic modulator. Three types of photonic devices are investigated. Firstly, an electrically tunable plasmonic subwavelength grating based on a metallic subwavelength slit array coupled with a Si/SiO2/ITO MOS capacitor is designed and demonstrated. We show that large modulation depth can be achieved for both transmission and reflection modes through modifying the electron concentration within 0.5 nm thick TCO accumulation layer. In the second part, we develop a novel device platform of TCO-gated silicon micro-resonators. A Si-TCO photonic crystal (PC) nanocavity modulator is designed and demonstrated. We achieve extreme large wavelength tuning of 250 pm/V, single digit femto-joule per bit energy efficiency, and 2.2 GHz operation bandwidth with a deep sub-λ ultra-small modulation volume. We also propose a strategy to improve bandwidth to over 23GHz and reduce energy consumption to atto-joule per bit level. Besides, TCO-gated microring resonators are investigated for two applications. We design and demonstrate a tunable microring filter with an unprecedented wavelength tuning of 271 pm/V, a large electrical tuning range of 2 nm, and a negligible static energy consumption, which can be used for wavelength division multiplex (WDM) application. A TCO-gated microring modulator is also designed, which can potentially achieve a large operation bandwidth over 50GHz. Lastly, a sub-micron, sub-pico-second, femto-joule level all-optical switch (AOS) using hybrid plasmonic-silicon waveguides driven by high mobility TCOs is proposed. By defining a comprehensive metric using the product of device size, switching energy and switching time, the proposed device shows superior performance than any existing on-chip AOS device. In addition to the device research, we systematically analyze the energy efficiency and bandwidth limit of resonator-based silicon photonic modulators from three fundamental perspectives: free carrier dispersion strength of the active materials, Purcell factors of the resonators, and electrical configuration of the capacitors. The analysis lays the theoretical foundation and identifies possible routes for achieving atto-joule per bit energy efficiency and approaching the bandwidth limit of silicon photonic modulators. In summary, TCOs could play an important role in the development of future photonics technology, which provide a CMOS compatible solution to overcome the intrinsic weak E-O effect of the silicon photonics platform, lead to unprecedented reduction in energy consumption, increasing bandwidth, as well as enable novel functionalities. Future researches should include, but not limited to, optimizing the design and fabrication of TCO-driven modulators to reduce series resistance and increasing overlapping factor, integrating TCO-driven devices with photonics foundry fabricated PICs, and developing of high mobility TCOs

New insight into the role of fibroblasts in the epithelial immune microenvironment in the single-cell era

The skin is exposed to environmental challenges and contains heterogeneous cell populations such as epithelial cells, stromal cells, and skin-resident immune cells. As the most abundant type of stromal cells, fibroblasts have been historically considered silent observers in the immune responses of the cutaneous epithelial immune microenvironment (EIME), with little research conducted on their heterogeneity and immune-related functions. Single-cell RNA sequencing (scRNA-seq) and spatial transcriptomics (ST) have overcome the limitations of bulk RNA sequencing and help recognize the functional and spatial heterogeneity of fibroblasts, as well as their crosstalk with other types of cells in the cutaneous EIME. Recently, emerging single-cell sequencing data have demonstrated that fibroblasts notably participate in the immune responses of the EIME and impact the initiation and progression of inflammatory skin diseases. Here, we summarize the latest advances in the role of fibroblasts in the cutaneous EIME of inflammatory skin diseases and discuss the distinct functions and molecular mechanisms of activated fibroblasts in fibrotic skin diseases and non-fibrotic inflammatory skin diseases. This review help unveil the multiple roles of fibroblasts in the cutaneous EIME and offer new promising therapeutic strategies for the management of inflammatory skin diseases by targeting fibroblasts or the fibroblast-centered EIME

On-chip near-infrared spectroscopy of CO₂ using high resolution plasmonic filter array

We report an ultra-compact, cost-effective on-chip near-infrared spectroscopy system for CO₂ sensing using narrow-band optical filter array based on plasmonic gratings with a waveguide layer. By varying the periodicity of the gratings, the transmission spectra of the filters can be continuously tuned to cover the 2.0 μm sensing window with high spectral resolution around 10 nm. Our experimental results show that the on-chip spectroscopy system can resolve the two symmetric vibrational bands of CO₂ at 2.0 μm wavelength, which proves its potential to replace the expensive commercial IR spectroscopy system for on-site gas sensing

Ultrashort Near-Infrared Fiber-Optic Sensors for Carbon Dioxide Detection

In this paper, we report a fiber-optic carbon dioxide (CO₂) near-infrared (IR) absorption sensor with only 8-cm sensing length that is coated with nanoporous metalorganic framework material Cu-BTC (BTC = benzene-1,3, 5-tricarboxylate). The multimode optical fiber was etched by hydrofluoric acid to remove the cladding and part of the core, resulting in larger evanescent field to sense the near-IR absorption induced by the adsorbed CO₂. The Cu-BTC thin film with 100 nm thickness was then grown onto the ethced core through a stepwise layer-by-layer method. Our real-time measurement results show that the CO₂ detection limit is better than 500 ppm and the overall response time is 40 s for absorption and 75 s for desorption. To the best of our knowledge, this is the shortest near-IR fiber-optic sensor for CO₂ detection at 1.57-μm wavelength.This is the publisher’s final pdf. The published article is copyrighted by Institute of Electrical and Electronics Engineers and can be found at: http://ieeexplore.ieee.org/xpl/RecentIssue.jsp?punumber=7361 ©2015 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale or redistribution to servers or lists, or reuse of any copyrighted components of this work in other works.Keywords: Fiber optic sensor, metal-organic framework, near infrared absorption, gas senso

Effect of Clozapine on Anti-N-Methyl-D-Aspartate Receptor Encephalitis With Psychiatric Symptoms: A Series of Three Cases

The main clinical manifestations of anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis are acute or subacute seizures, cognition impairment, and psychiatric symptoms. Nowadays, the scheme of antipsychotic therapy for this disease has not been established. This study reports three cases of anti-NMDAR encephalitis with psychiatric symptoms. The anti-NMDAR antibodies in cerebrospinal fluid (CSF) and serum were positive. The psychiatric symptoms still existed after intravenous immunoglobulin (IVIG) treatment; thus, clozapine was used for antipsychotic therapy. Case 1 was a 37-year-old man who suffered from bad mood and suicide behaviors for 1 month. Hallucination and delusion still existed after IVIG treatment and hormone therapy, and the symptoms were relieved when given clozapine for 12 months. Case 2 was a 28-year-old man who was admitted to our hospital due to injuring other people and destructive behaviors for 2 days. He showed irritability, bad temper, declined cognition, and severe delusion of persecution after IVIG treatment and hormone therapy, but the psychiatric symptoms disappeared when given clozapine for 3 months. Case 3 was a 23-year-old man who suffered from headache and babbing for 7 days. Symptoms such as irritability, bad temper, babbing, and injuring other people still existed after IVIG treatment and hormone therapy, but they disappeared when given clozapine for 2 months. Therefore, we suggest that during the treatment of anti-NMDAR encephalitis with psychiatric symptoms, if the anti-NMDAR antibodies in CSF and serum were positive, and psychiatric symptoms could not be controlled after IVIG and hormone therapy, clozapine may work

Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome associated with COVID-19: An Emulated Target Trial Analysis.

RATIONALE: Whether COVID patients may benefit from extracorporeal membrane oxygenation (ECMO) compared with conventional invasive mechanical ventilation (IMV) remains unknown. OBJECTIVES: To estimate the effect of ECMO on 90-Day mortality vs IMV only Methods: Among 4,244 critically ill adult patients with COVID-19 included in a multicenter cohort study, we emulated a target trial comparing the treatment strategies of initiating ECMO vs. no ECMO within 7 days of IMV in patients with severe acute respiratory distress syndrome (PaO2/FiO2 <80 or PaCO2 ≥60 mmHg). We controlled for confounding using a multivariable Cox model based on predefined variables. MAIN RESULTS: 1,235 patients met the full eligibility criteria for the emulated trial, among whom 164 patients initiated ECMO. The ECMO strategy had a higher survival probability at Day-7 from the onset of eligibility criteria (87% vs 83%, risk difference: 4%, 95% CI 0;9%) which decreased during follow-up (survival at Day-90: 63% vs 65%, risk difference: -2%, 95% CI -10;5%). However, ECMO was associated with higher survival when performed in high-volume ECMO centers or in regions where a specific ECMO network organization was set up to handle high demand, and when initiated within the first 4 days of MV and in profoundly hypoxemic patients. CONCLUSIONS: In an emulated trial based on a nationwide COVID-19 cohort, we found differential survival over time of an ECMO compared with a no-ECMO strategy. However, ECMO was consistently associated with better outcomes when performed in high-volume centers and in regions with ECMO capacities specifically organized to handle high demand. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.0 (http://creativecommons.org/licenses/by-nc-nd/4.0/)